Clinical trials: asthma
Asthma
A Long-term Safety Study of Fluticasone Furoate (FF)/GW642444 and FF in Japanese Subjects With Asthma
The primary purpose of the study is to assess the safety and tolerability of 52-week teatment with fluticasone furoate/GW642444 inhalation powder once-daily and FF inhalation powder once-daily in Japanese adult subjects with…
- Trial name
- NCT01244984
- Testing
- Fluticasone Furoate/GW642444 Inhalation Powder, Fluticasone Furoate Inhalation Powder
- Where
- 30 sites in Japan
- Volunteers
- 243 people
- Sponsor
- GlaxoSmithKline
Asthma, Obesity
Pilot Study of Pioglitazone for the Treatment of Moderate to Severe Asthma in Obese Asthmatics (Glitz Asthma)
Asthmatics who are significantly overweight tend to have more severe symptoms, more flare ups, and are more likely to have poorly-controlled asthma when compared to other asthmatics.
- Trial name
- GLITZ (NCT00787644)
- Testing
- Pioglitazone
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Vermont
Rhinitis, Allergic, Perennial, Asthma
Biomarker-based Cockroach Sublingual Immunotherapy Study (BioCSI)
There is currently no effective way to prevent development of allergic rhinitis (nasal allergies) and asthma and no cure. Sublingual immunotherapy (SLIT), a type of therapy in which allergens are placed under the tongue, may be a…
- Trial name
- NCT00829985
- Testing
- Glycerinated German Cockroach Allergenic Extract
- Where
- 4 sites in United States
- Volunteers
- 54 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma
Non-Interventional Study to Describe the Clinical Management in Asthmatic Patients (NICMA)
Asthma is a heterogenic chronic disease that affects more than 300 million people worldwide, which it's characterized by acute symptomatic episodes of varying severity, including intermittently inflammation and narrowing of the…
- Trial name
- (NICMA) (NCT06811155)
- Where
- Spain
- Volunteers
- 288 people
- Sponsor
- Hospital Universitario Virgen de la Victoria
Asthma
Safety and Efficacy Study of Budesonide (Pulmicort®) Turbuhaler® in Japanese Children With Bronchial Asthma
This study will include the patients who are Japanese children with bronchial asthma aged 5 years to 15 years old and have completed the Phase III study (Study code: D5254C00769) at about 29 centres.
- Trial name
- NCT00509028
- Testing
- Budesonide, Conventional Asthma Therapy
- Where
- Japan
- Volunteers
- 241 people
- Sponsor
- AstraZeneca
Asthma
A Randomized Trial Examining the Effectiveness of Mobile-Based Asthma Action Plans vs. Paper Asthma Action Plans
The purpose of this study is to see if using a mobile phone application asthma action plan will help improve asthma management.
- Trial name
- PEAK2 (NCT02091869)
- Testing
- Paper Asthma Action Plan, Mobile Phone
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Asthma
Montelukast in Pediatric Patients Aged 6 to 24 Months With Asthma--Safety Study (0476-176)
A study of Montelukast compared to placebo in asthmatic children aged 6-24 months.
- Trial name
- NCT00943683
- Testing
- montelukast sodium
- Volunteers
- 256 people
- Sponsor
- Organon and Co
Asthma
Efficacy and Safety Study in Subjects With Asthma
The study is a multi-center, double-blind, placebo-controlled, cross-over study to evaluate the efficacy and safety of selected doses and dose intervals of the novel long acting beta agonist (LABA), GW642444 in asthmatic subjects…
- Trial name
- NCT00980200
- Testing
- Dose 4 QD, Dose 3 QD, Dose 2 QD
- Where
- 9 sites in United States
- Volunteers
- 75 people
- Sponsor
- GlaxoSmithKline
Asthma
Azithromycin for Children Hospitalized With Asthma
Asthma is a chronic lung condition in children, and often requires hospitalization for acute exacerbations. Azithromycin has been used successfully in other chronic lung diseases, including cystic fibrosis.
- Trial name
- NCT02003911
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Montefiore Medical Center
Sickle Cell Disease, Vitamin D Deficiency
Vitamin D for Sickle-cell Respiratory Complications
This study aims to answer the question whether oral vitamin D supplementation can decrease lung complications in children and adolescents with sickle cell disease.
- Conditions
- Sickle Cell Disease, Vitamin D Deficiency, Acute Chest Syndrome, Asthma
- Trial name
- NCT01443728
- Testing
- Experimental: Vitamin D3 100,000 IU, Active Comparator: Vitamin D3 12,000 IU
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Gary M Brittenham, MD
Asthma, Allergic Sensitization
Promoting Tolerance to Common Allergens in High-Risk Children: Global Prevention of Asthma in Children (GPAC) Study
The purpose of this study is to determine whether early childhood exposure to common allergens (substances that can trigger allergies and asthma) can prevent the development of asthma in children at high risk for developing the…
- Trial name
- GPAC (NCT00346398)
- Testing
- Oral mucosal immunoprophylaxis (OMIP)
- Where
- 3 sites in United States, Australia
- Volunteers
- 51 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma, Obesity
MitoQ for the Treatment of Metabolic Dysfunction in Asthma
A 14-week, randomized, placebo-controlled, double-masked clinical trial in 40 obese patients with poorly controlled asthma. The intervention is Mitoquinol (MitoQ) versus placebo.
- Trial name
- MIMDA (NCT04026711)
- Testing
- Mitoquinol
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- University of Vermont
Exercise Induced Asthma
Trial on the Effect of Budesonide/Formoterol and Inhaled Budesonide Alone on Exercise-Induced Asthma
The purpose of this study is to find out if Symbicort® (budesonide/formoterol), a new combination asthma medication, is more effective than budesonide alone in controlling exercise induced asthma.
- Trial name
- NCT01070888
- Testing
- Budesonide/Formoterol, Budesonide
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Boston Children's Hospital
Asthma
Feasibility and Acceptability of the Propeller Monitoring System in Children With Persistent Asthma
The main hypothesis of this study is to see if children and adolescents with poorly controlled asthma will find the Propeller electronic monitoring device is feasible and acceptable, and will result in improved medication…
- Trial name
- NCT03648450
- Testing
- Propeller EMD
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Connecticut Children's Medical Center
Lung Diseases, Asthma
Montelukast for Early Life Wheezing
This study will determine the effects of montelukast on the duration of wheezing in children 12 months to 3 years of age who visit a physician for care of a wheezing illness.
- Trial name
- NCT00115297
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Massachusetts, Worcester
Asthma
Phase IV Study in Asthma Subjects for Dry Powder Inhaler (DPI) Versus (vs) Metered Dose Inhaler (MDI) Correct Use
The study is conducted to evaluate the potentially improved patient handling of the ELLIPTA Dry Powder Inhaler (DPI). Therefore, the study aims to evaluate errors encountered by subject with asthma during handling ELLIPTA DPI…
- Trial name
- NCT02794480
- Testing
- ELLIPTA DPI, GSK MDI, AZ MDI
- Where
- 20 sites in United States
- Volunteers
- 324 people
- Sponsor
- GlaxoSmithKline
Asthma
To Compare the Pharmacokinetics of Budesonide Delivered by BDA MDI to Budesonide Delivered by Pulmicort Respules in Children With Asthma Aged 4 to 8 Years.
To compare the pharmacokinetics of budesonide delivered by BDA MDI to budesonide delivered by Pulmicort Respules in children with Asthma aged 4 to 8 years.
- Trial name
- BLANC (NCT04848662)
- Testing
- BDA MDI (PT027) 160/180 μg, Pulmicort Respules 0.5 MG/ML Inhalation Suspension
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Bond Avillion 2 Development LP
Asthma
The Effects of Different Long-acting Bronchodilator Medications on Asthma Patients With Different Genetic Variations
This study is looking at the effects of certain long-acting bronchodilators on patients with asthma who have specific genetic variations.
- Trial name
- GABLE (NCT00706446)
- Testing
- tiotropium bromide, Salmeterol, Formoterol
- Where
- 2 sites in United States
- Volunteers
- 255 people
- Sponsor
- Brigham and Women's Hospital
Asthma
Clinical Study Evaluating Safety and Efficacy of Fluticasone Furoate and Fluticasone Propionate in People With Asthma
A randomised, double-blind, double-dummy, placebo controlled multi-centre study to evaluate the efficacy and safety of fluticasone furoate inhalation powder and fluticasone propionate inhalation powder in the treatment of asthma…
- Trial name
- NCT01436110
- Testing
- Fluticasone furoate 50mcg, Fluticasone propionate 100mcg
- Where
- 42 sites in United States, Mexico and 4 more
- Volunteers
- 351 people
- Sponsor
- GlaxoSmithKline
Severe Asthma
Long-term Safety of Tezepelumab in Japanese Subjects With Inadequately Controlled Severe Asthma
This is an open-label, single arm study designed to evaluate the safety of tezepelumab administered subcutaneously every 4 weeks in Japanese adult and adolescent subjects with inadequately controlled severe asthma.
- Trial name
- NOZOMI (NCT04048343)
- Testing
- Biological: Experimental: Tezepelumab
- Where
- 5 sites in Japan
- Volunteers
- 65 people
- Sponsor
- AstraZeneca
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