Clinical trials: asthma
Allergic Asthma
Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled O3 Exposure
To study the effects of 1200mg gamma tocopherol, a form of vitamin E, given daily on the response of the airway in mild asthmatics after exposure to ozone (O3)
- Trial name
- Gammoz (NCT02911688)
- Testing
- gamma tocopherol
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of North Carolina, Chapel Hill
Asthma
The Impact of Dosimeter on Measurement of Airway Responsiveness to Methacholine
To determine whether there is a difference in two different breathing tests used to detect asthma. Hypothesis: The Digidoser delivers less methacholine to the airways and will result in a higher PC20 than the value determined by…
- Trial name
- NCT00145990
- Testing
- methacholine, KoKo Digidoser, Rosethal Dosimeter
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Asthma
A Study of ARRY-502 in Patients With Persistent Asthma
This is a Phase 2 study, involving a 6-week treatment period, designed to evaluate the effectiveness of investigational study drug ARRY-502 in treating mild to moderate persistent asthma, and to further evaluate the safety of the…
- Trial name
- NCT01561690
- Testing
- ARRY-502, CRTh2 antagonist; oral
- Where
- 43 sites in United States
- Volunteers
- 184 people
- Sponsor
- Pfizer
Bronchial Asthma, Adherence, Medication
Cognitive and Emotional Factors Relation to Treatment Adherence in Asthmatic Patients in Upper Egypt
Non-adherence to controller therapy is one of the main reasons of poor asthma control. Adherence to medication in different studies range between 30 and 70% .
- Trial name
- NCT06200623
- Volunteers
- 138 people
- Sponsor
- Entsar Hsanen
Asthma
Longitudinal Assessment of Children With Severe Asthma and Severe Pre-school Wheeze
Cross-sectional study to characterize cohorts of children with asthma and healthy controls in terms of clinical features, physiological measurements and non-invasive measurement of biomarkers and develop phenotype handprints for…
- Trial name
- NCT01982162
- Volunteers
- 300 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Asthma; Eosinophilic
The Influence of Inhaled CorticoSteroids Adherence on Treatment Response to Mepolizumab in Severe Eosinophilic Asthma
The study aim is to look at the effect of the regular use of inhaled corticosteroids on the response and received from mepolizumab treatment which you are receiving or had received before.
- Trial name
- CSAREA (NCT05241769)
- Volunteers
- 250 people
- Sponsor
- University Hospital Birmingham
Bronchial Asthma
Additive Effects of Alternative Nostril Breathing with Pharmacological Management on Dyspnea and Control Pause in Patients with Bronchial Asthma
Bronchial asthma is a widespread chronic condition charactrized by inflammation and narrowing of airways, leading to repeateted episodes of breathlessness, wheezing and labored breathing.Breathing exercises help to manage…
- Trial name
- NCT06609941
- Testing
- Alternative nostril breathing, Pharmacological therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Foundation University Islamabad
Severe Asthma, COPD
K-HEALTH in AIR - Barcelona Pilot - Cohort
The study protocol is part of the European (EU) project "Knowledge for improving indoor AIR quality and HEALTH" (K-HEALTHinAIR, 2022-2026 - registry 101057693), which focuses on enhancing our understanding of how poor indoor air…
- Trial name
- NCT06421402
- Testing
- Air quality monitoring at patient's home, Questionnaires: Baseline & every six months, Lung function Testing: Baseline & every six months & during exacerbations
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
Asthma
Pulmicort Respules(Budesonide Inhalation Suspension) vs Singulair, Children
A one year study comparing the safety and effectiveness of Pulmicort (0.5mg strength given once a day in the evening) with either 4 or 5mg strength SINGULAR (given once a day in the evening) in children with asthma aged 2 to 8.
- Trial name
- NCT00641472
- Testing
- Budesonide inhalation suspension, Montelukast Sodium
- Volunteers
- 380 people
- Sponsor
- AstraZeneca
Food Allergy Suspected, Food Allergy Proved
Association Between Asthma and Food Allergy
Prevalences of food allergies and asthma increased in the population during the last decades. These two pathologies, responsible for a real burden, are often associated and are to be considered as comorbidities; this aspect is…
- Trial name
- AAAli (NCT02884583)
- Testing
- Pulmonary function test
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Asthma
CIVETTA: Correlating Inflammatory Values of FEno, SympToms, SpuTum and Lung Function in Asthma
Single-center, interventional, open-label, randomized phase II study aimed at describing the changes in airway inflammation at the onset of asthma symptoms that lead to the use of rapid acting bronchodilator (RABD) as a rescue…
- Trial name
- NCT06482294
- Testing
- Salbutamol, Fluticason either Beclometasone or Budesonide
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Ferrara
Healthy
Preventive Medicine Study of Childhood Atopic Diseases
Under environmental intervention programs, to explore the associations between Environmental Tobacco Smoke (ETS) and changes of pulmonary function, cytokines and new-onset asthma between different groups.
- Trial name
- NCT00960596
- Testing
- Health promotion and health education for smoking habits
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Asthma
NIS for Patients Using Symbicort Turbuhaler for Maintenance and Reliever Therapy in a Single Inhaler
The aim of this non-interventional study is to ensure that patients in routine clinical practice follow given treatment instructions and to evaluate the number of reliever inhalations as well as the number of patient/days with…
- Trial name
- SYMCO (NCT00557297)
- Where
- 22 sites in Latvia
- Volunteers
- 250 people
- Sponsor
- AstraZeneca
Asthma Chronic, Adherence, Medication
Pictograms to Facilitate Comprehension of Medical Indications
SIMAP is a triple-masked randomised trial aimed at assessing whether an automated system of pictograms associated to medical indications results in better comprehension and adherence of said indications.
- Conditions
- Asthma Chronic, Adherence, Medication, Primary Health Care
- Trial name
- SIMAP (NCT05609760)
- Testing
- SIMAP, Usual Care
- Where
- 4 sites in Chile
- Volunteers
- 22 people
- Sponsor
- Universidad de Concepcion
Asthma
Prospective Study on Asthma Control
Accordingly, the new update of the Global Initiative for Asthma (GINA) guidelines 2006 is based on the control of the disease and attempts to quantify and graduate the level of control by using a classification of asthmatic…
- Trial name
- PRISMA (NCT01110460)
- Volunteers
- 2,875 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Asthma, Lung Diseases
Home Based Environmental Adherence Trial
To conduct a randomized trial in asthmatic children to compare the effectiveness of a home-based allergen control program with a customary educational program delivered in offices
- Trial name
- NCT00005523
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma, Adherence, Medication
Evaluating Efficacy of Smart Device in Assisting With Inhaler Technique and Adherence
Asthma affects over 10 million children in the U.S., and poses a significant health and cost burden. Metered dose inhaler (MDI) is the most common method of treatment.
- Conditions
- Asthma, Adherence, Medication, Childhood Asthma
- Trial name
- MOMMIASTHMA1 (NCT04250779)
- Testing
- CapMedic smart inhaler device, Video-based guidance
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Landon Pediatric Foundation
Asthma
Biomarkers of Irritant-Induced and Allergic Asthma
Asthma is a heterogeneous disease, and although much is understood about mechanisms of inflammation in allergic asthma, less is known about mechanisms of irritant-induced asthma (IA).
- Trial name
- NCT02740543
- Testing
- Fluticasone propionate HFA 220
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Asthma
Study Evaluating Etanercept in Moderate to Severe Asthma
The primary objective of the study is to assess the efficacy and safety of etanercept 25 mg given twice weekly in subjects with moderate to severe persistent asthma.
- Trial name
- NCT00141791
- Testing
- Etanercept
- Where
- 13 sites in United States
- Volunteers
- 120 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Asthma, Anxiety
Efficacy of the Combination of Mindfulness and Buteyko Techniques for the Improvement of Poorly Controlled Asthma.
Administration of a combined program for general (Mindfulness) and respiratory (Buteyko technique) relationship in patients with poorly controlled asthma and anxiety/stress to determine if it provides an improvement in current…
- Conditions
- Asthma, Anxiety, Stress
- Trial name
- NCT05593315
- Testing
- Mindfulness and Buteyko techniques
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
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