Clinical trials: asthma
Asthma in Children
The Long-term Effect of RSV Infection
Respiratory Syncytial Virus (RSV) is a leading cause of childhood illness and hospitalization across the world. In addition to acute mortality and morbidity, RSV infection is associated with developing recurrent wheeze in…
- Trial name
- NCT03876249
- Testing
- exposure to RSV
- Volunteers
- 2,000 people
- Sponsor
- Child Health Research Foundation, Bangladesh
Severe Asthma
"SEVERE ASTHMA" in the COMMUNITY
SEVERE ASTHMA IN THE COMMUNITY- BACKGROUND Severe asthma is a common problem. In the world approximately 300 million people have asthma but it is estimated that only 5% of these patients have severe asthma.
- Trial name
- NCT01961258
- Testing
- Computerized data base analysis and sampling of patients for outpatient clinic evaluation
- Volunteers
- 250 people
- Sponsor
- Meir Medical Center
Asthma
A Study To Assess The Effect Of PF-03893787 On Lung Function Following An Allergen Challenge In Asthmatic Subjects
PF-03893787, a novel anti-inflammatory agent should attenuate the effect of a bronchial allergen challenge on lung function and hence provide proof of mechanism for this agent.
- Trial name
- NCT00856687
- Testing
- PF-03893787, Montelukast
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Pfizer
Asthma in Children, Implementation
Y of Central Maryland Head Start Asthma Implementation
Despite a strong evidence-base for the efficacy of multilevel programs in reducing asthma symptoms among low-income preschool minority children, gaps remain in our understanding of how to best translate and scale up these…
- Conditions
- Asthma in Children, Implementation, Preschool Children
- Trial name
- NCT05004714
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Johns Hopkins University
Asthma
Study in Patients With Asthma
The purpose of this study is to determine which dose of the investigational drug is safest and most effective compared to the control drug.
- Trial name
- NCT00215358
- Testing
- Formoterol Fumarate
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Dey
Asthma, Bronchial Hyperreactivity
Early Antiinflammatory Treatment of Asthma
The inflammatory process that leads to the development of asthma may be present before the onset of asthma symptoms and cause a certain degree of airway hyperresponsiveness.
- Trial name
- EATA (NCT00567463)
- Testing
- Fluticasone
- Where
- Canada
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Laval University
Copd, COPD Exacerbation
Telehealth and Onsite Maintenance Exercise in Chronic Lung Disease
The goal of this pilot clinical trial is to compare telehealth and onsite supervised maintenance exercise program for adults with Chronic Lung Disease.
- Conditions
- Copd, COPD Exacerbation, COPD Bronchitis, Emphysema or COPD
- Trial name
- CLD (NCT06304207)
- Testing
- Onsite Maintenance Exercise Training, Telehealth Maintenance Exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- MGH Institute of Health Professions
Asthma
Efficacy and Safety Study to Compare Formoterol Fumerate in the Pressair DPI to the Foradil Aerolizer in Patient With Mild to Moderate Asthma
The purpose of this Phase II study is to evaluate efficacy and safety of inhaled formoterol fumarate in the Pressair DPI compared to the Foradil Aerolizer in patients with mild to moderate asthma.
- Trial name
- NCT01641081
- Testing
- Formoterol Fumarate in the Pressair DPI, Low Dose, Formoterol Fumarate in the Pressair DPI, High Dose, Foradil Aerolizer, Low Dose
- Where
- 29 sites in United States
- Volunteers
- 174 people
- Sponsor
- AstraZeneca
Asthma
Improving Asthma Care for Very Low Birth Weight Infants
Children born less than 1500 grams are being enrolled into a study to test the effectiveness of a parental educational intervention in reducing the risk of future breathing problems.
- Trial name
- NCT00156507
- Testing
- Asthma education for parents of very low birth weight infants
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- University of Rochester
Asthma
Efficacy and Safety of Levalbuterol Versus Racemic Albuterol in Asthma
To investigate the Efficacy and Safety of Levalbuterol versus Racemic Albuterol in the Treatment of Acute Asthma.
- Trial name
- NCT00667407
- Testing
- Levalbuterol 1.25 mg, Racemic Albuterol Sulfate
- Where
- 28 sites in United States
- Volunteers
- 627 people
- Sponsor
- Sumitomo Pharma America, Inc.
Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
Quantitative Chest CT and Multi-Omics to Distinguish Asthma From COPD and Predict Treatment Response
This study aims to improve the diagnosis and treatment prediction of asthma and chronic obstructive pulmonary disease (COPD) by combining quantitative chest computed tomography (CT) imaging with multi-omics data.
- Trial name
- CTOMICS (NCT07602192)
- Where
- 2 sites in South Korea
- Volunteers
- 200 people
- Sponsor
- Korea University Guro Hospital
Asthma, Lung Diseases
Self Management Education Asthma
To evaluate the effects of a new statewide program to enhance identification, referral and provision of care to rural families of Hispanic children with moderately severe to severe asthma.
- Trial name
- NCT00005712
- Sponsor
- University of New Mexico
Bronchial Asthma
Study on the Safety and Efficacy of PA9159 Inhalation Aerosol for the Treatment of Adult Bronchial Asthma
PA9159 is a highly potent novel corticosteroid. The purpose of this study is to evaluate the safety, efficacy and characteristics of population pharmacokinetics of multiple dosing of PA9159 Inhaler in patients with bronchial…
- Trial name
- NCT07324707
- Testing
- PA9159 Metered-Dose Inhaler, 120 μg per day for 28 days, Fluticasone Propionate Inhaled Aerosol 200 μg per day for 28 days
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Anhui Palo Alto Pharmaceuticals, Inc.
Asthma, Pertussis
Prevalence and Impact of Pertussis and RSV on Asthma Severity and Control
The main objective is to estimate the annual symptomatic incidence of Bordetella pertussis and RSV infections in patients aged 18 years and over with asthma, which will be identified by PCR, for Bordetella pertussis and by PCR…
- Conditions
- Asthma, Pertussis, RSV Infection
- Trial name
- PRIPASCO (NCT06286007)
- Testing
- PCR
- Where
- Spain
- Volunteers
- 784 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Diagnosing Obstructive Lung Disease With Point of Care Ultrasound
The objective of this study is to evaluate the diagnostic accuracy of Point of Care Ultrasound (POCUS) in identifying obstructive lung diseases (OLDs), using pulmonary function tests (PFTs) as the gold standard for comparison.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive, Asthma, COPD
- Trial name
- NCT06251271
- Testing
- Point-of-Care Ultrasound
- Where
- Israel
- Volunteers
- 301 people
- Sponsor
- Soroka University Medical Center
Emphysema, Acute Respiratory Distress Syndrome
Use of the Hattler Respiratory Assist Catheter in Severe Respiratory Failure
A new artificial lung device has been developed that potentially provides added support to mechanical ventilation for severely damaged lungs.
- Conditions
- Emphysema, Acute Respiratory Distress Syndrome, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT00288964
- Testing
- Hattler Respiratory Assist Catheter
- Where
- United Kingdom
- Sponsor
- Alung Technologies
Atopic Asthma
Airway Response to Repeat Allergen Challenge and the Effect of Ibuprofen in Mild Atopic Asthma
The study will assess airway responses in mild atopic asthmatics undergoing repeat allergen challenge testing and will investigate whether ibuprofen changes the response.
- Trial name
- NCT02327234
- Testing
- ibuprofen
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- University of Saskatchewan
Asthma
Aerosol Delivery in Different Types of Nebulizers
Background: Nebulizers design influences efficiency of aerosol delivery. Performance of nebulizers is commonly tested by breathing simulators with static parameters. However, breathing patterns vary in adults.
- Trial name
- NCT02764307
- Testing
- Constant jet nebulizer, Breath enhanced nebulizer, Manual-actuated nebulizer
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Asthma
Ultra-long Acting Bronchodilator Therapy in Asthmatics
Asthma is a common condition which produces a significant workload for general practice, hospital outpatient clinics and inpatient admissions.
- Trial name
- MAN02 (NCT02039011)
- Testing
- Indacaterol, Indacaterol and tiotropium
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- University of Dundee
Respiratory Function Tests
Exercise Induced Asthma and Airway Reactivity in Athletes
The overall aim is to explore pathophysiological factors related to airway hyperresponsiveness to direct and indirect provocation stimuli in athletes with different sport activities, with special focus on epithelial reaction…
- Trial name
- NCT00798564
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
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