Clinical trials: asthma
Dysfunctional Breathing, Asthma in Children
The Prevalence of Dysfunctional Breathing in Children and Adolescents With Asthma
The purpose of the study is to investigate the prevalence of dysfunctional breathing in children and adolescents with asthma in a hospital outpatient clinic.
- Conditions
- Dysfunctional Breathing, Asthma in Children, Asthma
- Trial name
- NCT04734795
- Where
- Denmark
- Volunteers
- 363 people
- Sponsor
- Kolding Sygehus
Asthma
Orthomolecular Therapy and Asthma in Children
The purpose of this study is 1. To pilot the research methodology for a randomized trial on an orthomolecular treatment regime versus placebo as add-on therapy for children with asthma; 2.
- Trial name
- NCT00672529
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Canadian Institute of Natural and Integrative Medicine
Asthma
Measuring Exhaled Nitric Oxide (eNO) Using the Apieron INSIGHT System and the Aerocrine NIOX System
Collection of quantitative data to demonstrate the accuracy (bias) and precision (repeatability) of the Apieron INSIGHT(tm) eNO Breath System as compared to the FDA cleared NIOX eNO Breath System when testing is performed by…
- Trial name
- NCT00739531
- Testing
- Exhaled nitric oxide (eNO)
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Apieron
Asthma, Inflammation
Mucins and Toll-like Receptors in Asthma
This study raises two main hypotheses: 1) Asthmatics patients who present with bronchial hypersecretion differ phenotypically from asthmatic patients without hypersecretion and 2) mucins in asthmatic patients with hypersecretion…
- Trial name
- MUCITOLL (NCT02948153)
- Testing
- clinical study
- Where
- Spain
- Volunteers
- 43 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Allergies, Allergic Rhinitis
Sublingual Immunotherapy Studies for Grass and Dust Mite Allergies
This is a study for children and adults who are interested in a new therapy for their allergies to dust mite and timothy grass. The new therapy is called sublingual immunotherapy and the investigators are testing if it is safe…
- Conditions
- Allergies, Allergic Rhinitis, Asthma
- Trial name
- SLIT (NCT01529437)
- Testing
- sublingual immunotherapy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Stanford University
Asthma Patients
EFFECTIVENESS of PROBIOTICS in ADULTS with MODERATE to SEVERE PERSISTENT ASTHMA
The objective of this study is to compare the effectiveness of probiotic as an adjuvant to standard therapy versus standard therapy alone in adult with moderate to severe persistent asthma in terms of 1.
- Trial name
- NCT06657066
- Testing
- Beclomethasone 200mcg, salbutamol 100mcg , Beclomethasone 200 mcg/Formoterol 6 mcg, 250 mg of lyophilized saccharomyces boulardii, Control (Standard treatment)
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- King Edward Medical University
Asthma
Disclosure of Smoking in Adolescents With Asthma
This is an exploratory randomised matched cohort pilot study. It is hypothesised that adolescents (aged 13-16 years) with asthma attending a secondary care outpatient asthma clinic, will disclose their smoking status to a doctor…
- Trial name
- NCT03047902
- Testing
- Group 1 - Parents will be present for the Questionnaire., Group 2- Parents will not be present for the Questionnaire
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Mindfulness, Compassion
Wisconsin Center for the Neuroscience and Psychophysiology of Meditation
The Wisconsin Center for the Neuroscience and Psychophysiology of Meditation will be a highly focused center dedicated to novel and cutting edge research on the mechanisms by which meditation works.
- Conditions
- Mindfulness, Compassion, Meditation, Mental Health
- Trial name
- NCT02157766
- Testing
- Intensive Meditation Practice, Mindfulness Based Stress Reduction, Health Enhancement Program
- Where
- 4 sites in United States
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Asthma
Using Technology-Assisted Stepped Care Intervention to Improve Adherence in Adolescents With Asthma
To test the preliminary efficacy of the TASC adherence promotion intervention for adolescents with asthma in a feasibility randomized controlled trial compared to treatment as usual control arm.
- Trial name
- TASC (NCT04365556)
- Testing
- TASC Intervention
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Asthma
Long-Term Safety of Symbicort in Asthmatic Children - SAPLING
The purpose of this study is to assess the safety of Symbicort compared to Pulmicort in asthmatic children aged 6 to 11 years
- Trial name
- NCT00646529
- Testing
- budesonide/formoterol (Symbicort), budesonide (Pulmicort)
- Volunteers
- 175 people
- Sponsor
- AstraZeneca
Respiratory Tract Infections, Asthma
DO IT Trial: Vitamin D Outcomes and Interventions In Toddlers
Vitamin D can be made in the skin by exposure to sunlight and can be found in certain foods. Vitamin D levels are alarmingly low in many North American children. Several health issues have been linked with low vitamin D.
- Conditions
- Respiratory Tract Infections, Asthma, Avitaminosis
- Trial name
- DO IT (NCT01419262)
- Testing
- Vitamin D - Cholecalciferol 400 IU, Vitamin D3 - Cholecalciferol 2000 IU
- Where
- 2 sites in Canada
- Volunteers
- 703 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Asthma
Forced Oscillation and Breathing Pattern in Asthma
Asthma is a chronic respiratory disease characterised by airway inflammation, bronchoconstriction, and airway hyperresponsiveness. Accurate and reliable assessment of lung function is crucial in diagnosing and monitoring asthma.
- Trial name
- NCT06272773
- Testing
- Forced Oscillation Test
- Volunteers
- 65 people
- Sponsor
- Karl Sylvester
Mild Allergic Asthma
Safety, Tolerability and Clinical Activity of ASM-024 in Subjects With Mild Allergic Asthma
The study will assess the safety, tolerability and clinical activity of ASM-024 in subjects with mild allergic asthma.
- Trial name
- NCT01092403
- Testing
- ASM-024
- Where
- 3 sites in Canada
- Volunteers
- 24 people
- Sponsor
- Asmacure Ltée
Schizophrenia, Psychosis
Early Detection of Respiratory Disorders in Psychosis
This study aims to evaluate the presence of lung function impairment in a sample of patients diagnosed with non-affective psychosis.
- Conditions
- Schizophrenia, Psychosis, Chronic Respiratory Disease
- Trial name
- NCT03476473
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundación Marques de Valdecilla
Respiratory Disease, Respiratory Failure
Clinical Evaluation of FreeO2 (Version 4) in All Patients Receiving Oxygen
Evaluation of automatic titration of oxygen with a new version of FreeO2 (V4)
- Conditions
- Respiratory Disease, Respiratory Failure, COPD Exacerbation, Asthma
- Trial name
- FreeO24G (NCT03119727)
- Testing
- FreeO2
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Laval University
Asthma
A Study of GSK3511294 (Depemokimab) in Participants With Severe Asthma With an Eosinophilic Phenotype
This study will assess the efficacy and safety of GSK3511294 (Depemokimab) as an adjunctive therapy in participants with severe uncontrolled asthma with an eosinophilic phenotype.
- Trial name
- SWIFT-2 (NCT04718103)
- Testing
- GSK3511294
- Where
- 129 sites in United States, Australia and 9 more
- Volunteers
- 397 people
- Sponsor
- GlaxoSmithKline
Asthma
China Alair System Registry Study-CARE Study
The objective of this Registry is to collect real-world outcome data for bronchial thermoplasty (BT) procedures in patients with severe persistent asthma who remain symptomatic despite taking standard of care maintenance…
- Trial name
- CARE (NCT02206269)
- Testing
- Alair System
- Where
- China
- Volunteers
- 225 people
- Sponsor
- BSC International Medical Trading (Shanghai) Co., Ltd.
Asthma
A Placebo and Active Controlled Study of ONO-6950 in Asthmatic Patients
The primary objectives of this study are: i. to determine the effect of single oral doses (20 and 200 mg) of ONO-6950 versus placebo on exercise induced bronchoconstriction (EIB) as percent attenuation in the decrease of forced…
- Trial name
- NCT01536041
- Testing
- ONO-6950, Montelukast
- Where
- 9 sites in United States
- Volunteers
- 59 people
- Sponsor
- Ono Pharma USA Inc
Asthma, Hypersensitivity
Effect of Heredity and Environment on Asthma Development and Severity in Puerto Rican Children
Asthma is a major public health problem among Puerto Ricans. Little is known, however, about the effect of heredity and environment on the development and severity of asthma in this population.
- Trial name
- NCT00461227
- Where
- Puerto Rico
- Volunteers
- 1,127 people
- Sponsor
- University of Pittsburgh
Asthma in Children
Evaluation of the Asthma Management Program to Promote Activity for Students in Schools (Asthma-PASS)
Physical activity (PA) is an important component of asthma management in children. Studies show that PA is associated with decreased severity of asthma symptoms, as well as improved disease control and quality of life.
- Trial name
- NCT04576442
- Testing
- Asthma-PASS, Basic Asthma Management (AM), Child/Caregiver Education session
- Where
- United States
- Volunteers
- 452 people
- Sponsor
- Montefiore Medical Center
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