Clinical trials: asthma
Asthma
Asthma in Central Texas Project
Asthma is the most common chronic childhood illness and disproportionately affects children who are ethnic minorities and poor. Few studies of childhood asthma have been conducted with children who live in rural areas or have…
- Trial name
- NCT01676896
- Testing
- Asthma in-school class, Asthma Day Camp, Health Promotion in-school class
- Where
- United States
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Asthma
Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma Exacerbation
The purpose of this study is to evaluate the effectiveness of nebulized magnesium sulfate as a vehicle for albuterol in children with moderate to severe asthma exacerbation.
- Trial name
- NCT01515995
- Testing
- Nebulized magnesium sulfate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas Southwestern Medical Center
Atopic Dermatitis, Eczema
Daily Use of Lipikar Balm AP From Birth in Infants at High Risk of Developing Atopic Dermatitis
There is a lack of prospective scientific data on the regular use of moisturizers in patients at risk of developing atopic dermatitis.
- Conditions
- Atopic Dermatitis, Eczema, Asthma, Food Allergies
- Trial name
- NCT01577628
- Testing
- Lipikar Balm AP
- Where
- 4 sites in United States, Canada
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Mild Persistent Asthma
Pharmacodynamic Bioequivalence of Metered Dose Inhalers of Albuterol Sulfate in Patients With Stable Mild Asthma
The purpose of this study is to demonstrate the pharmacodynamic bioequivalence of the test product to the reference product, using bronchoprovocation (methacholine challenge testing) in adult patients with stable mild asthma.
- Trial name
- NCT02584257
- Testing
- methacholine chloride, ProAir HFA, Lupin albuterol HFA MDI
- Where
- 17 sites in United States
- Volunteers
- 217 people
- Sponsor
- Lupin, Inc.
Asthma
p38 Mitogen-Activated Protein Kinase (MAPK) and Steroid Insensitivity in Asthma
This research aims to find out how the inflammation in patients suffering from severe asthma is different from that in non-severe asthma, and how it may prevent corticosteroids from working efficiently in severe asthma.
- Trial name
- NCT00676572
- Testing
- Fiberoptic bronchoscopy; blood test
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Imperial College London
Uncontrolled Asthma
A Phase 3 Study to Evaluate the Efficacy and Safety of Tralokinumab in Adults and Adolescents With Uncontrolled Asthma
A 52-Week, Multicentre, Randomized, Double-Blind, Parallel Group, Placebo Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Tralokinumab in Adults and Adolescents with Asthma Inadequately Controlled on Inhaled…
- Trial name
- STRATOS1 (NCT02161757)
- Testing
- Tralokinumab
- Where
- 243 sites in United States, Argentina and 13 more
- Volunteers
- 1,207 people
- Sponsor
- AstraZeneca
Asthma
Randomized Prospective Trial of a Mobile Health Application for Asthma Self-Management
The investigators aim to study the clinical efficacy of a mobile health application, AsthmaCare, and it's impact on long term health outcomes for asthma.
- Trial name
- AsthmaCare (NCT02333630)
- Testing
- AsthmaCare mobile health application, Asthma education
- Volunteers
- 200 people
- Sponsor
- David Stukus
Asthma
The Study is Enrolling Kids From 8 to 17 Years Old. The BreathSmart Device Attaches to the Inhaler to Measure Adherence.
Non-adherence to controller medication is a common problem in children with Asthma, resulting in overuse of reliever medication, increased asthma symptoms, more frequent Asthma attacks, and increased emergency room visits and…
- Trial name
- NCT03734861
- Testing
- BreatheSmart System, Standard of Care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Connecticut Children's Medical Center
Depression, Asthma
Antidepressant Treatment at an Inner City Asthma Clinic
Asthma is common with an increasing prevalence and mortality especially in low-income and minority populations. The course of asthma appears to be influenced by mood and emotions.
- Trial name
- NCT01324700
- Testing
- High severity group: Escitalopram, Low severity group: Escitalopram
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- University of Texas Southwestern Medical Center
Asthma
Improving Asthma Control in the Real World: A Systematic Approach to Improving Dulera Adherence
40 subjects with moderate-to-severe asthma will be randomly selected for study in which 20, will be monitored for medication use (Dulera 100/5, Dulera 200/5 and Proventil HFA) over 3 months.
- Trial name
- NCT02045875
- Testing
- Dulera
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Asthma Management Systems
Asthma
The Electronic Asthma Action Plan System for Implementation in Primary Care
Asthma is a common and potentially fatal chronic disease. An asthma action plan (AAP) is a written plan produced by a physician for a patient with asthma, to provide education and guidelines for self-management of worsening…
- Trial name
- eAAPS (NCT01070095)
- Testing
- Electronic Asthma Action Plan System
- Where
- 3 sites in Canada
- Volunteers
- 19 people
- Sponsor
- Unity Health Toronto
Asthma
A Study of 2 Doses of MAP0010 and Placebo in Asthmatic Children
The purpose of this study is to examine the safety and efficacy of two doses of MAP0010 versus placebo in asthmatic infants and children, 12 months to 8 years of age, over a 12-week treatment period.
- Trial name
- NCT00569192
- Testing
- 0.135mg MAP0010, 0.25mg MAP0010
- Volunteers
- 360 people
- Sponsor
- Allergan
Asthma
Efficacy and Safety of Different Doses of Indacaterol
This study compared the 14-day bronchodilator efficacy of indacaterol with that of placebo and salmeterol
- Trial name
- NCT01079130
- Testing
- Indacaterol, Salmeterol
- Where
- 71 sites in United States
- Volunteers
- 511 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
A Clinical Trial to Test a Study Drug in Volunteers Who Develop Asthma Following Exercise
This study is intended to determine the dose response and duration of action of GSK2190915 in mild asthmatic adult subjects who experience exercise-induced bronchoconstriction.
- Trial name
- NCT00812929
- Testing
- GSK2190915
- Where
- 6 sites in United States
- Volunteers
- 47 people
- Sponsor
- GlaxoSmithKline
Asthma
Evaluation of Triple Therapy Using Magnetic Resonance Imaging in Asthma
The purpose of this study is to evaluate the effectiveness of treatment with triple therapy an inhaler that contains three types of asthma medications, on participants with poorly controlled asthma.
- Trial name
- ETHA (NCT04651777)
- Testing
- FF/UMEC/VI
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Dr. Grace Parraga
Asthma, Inflammation
L-arginine in Severe Asthma Patients Grouped by Exhaled Nitric Oxide Levels
The major impact of this study will be to identify the adult severe asthma cohort that will benefit from supplemental L-arginine therapy.
- Trial name
- NCT01841281
- Testing
- L-Arginine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Nicholas Kenyon
Asthma
Study to Evaluate the Bronchoprotective Effects of a Single Dose of N6022 in Patients With Mild Asthma
The purpose of this study is to determine whether a single IV dose of N6022 will have a significant bronchoprotective effect, compared with placebo, during methacholine challenge.
- Trial name
- NCT01316315
- Testing
- Active
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Nivalis Therapeutics, Inc.
Asthma
A 3-period Crossover Study With GSK573719 as Monotherapy in Adult Subjects With Asthma
This is a multi-national, randomized, double-blind, 3-period crossover, incomplete block design to evaluate 5 once-daily and 2 twice-daily doses of GSK573719 in combination with placebo.
- Trial name
- NCT01641692
- Testing
- GSK573719 (Sub-group cohort), Salbutamol/Albuterol
- Where
- 43 sites in United States, Bulgaria and 4 more
- Volunteers
- 350 people
- Sponsor
- GlaxoSmithKline
Asthma
Responsiveness of Lower Airways in Adult Patients (18-60 Years) With Stable Asthma After Treatment With Ciclesonide and Fluticasone Propionate (BY9010/NL-101)
The aim of this study is to compare the responsiveness of lower airways in adult patients with stable asthma after treatment with ciclesonide and fluticasone propionate.
- Trial name
- NCT00306163
- Testing
- Ciclesonide, Fluticasone
- Where
- Netherlands
- Volunteers
- 37 people
- Sponsor
- AstraZeneca
Asthma
Drug Delivery Via Pressurized Metered-dose Inhaler and Valved Holding Chamber in Asthmatic Children: Determination of Delivered Dose Following Coordinated and Uncoordinated Use
The primary objective of this study is to determine ex vivo the amount of fluticasone deposited onto a filter (delivered dose) interposed between the OptiChamber Diamond Valved Holding Chamber (VHC) mouthpiece and the subject's…
- Trial name
- NCT01714063
- Testing
- Pressurized Metered-Dose Inhaler
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Philips Respironics
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