Clinical trials: asthma
Asthma
Estimating Quality of Life in People With Asthma
The aim of this project is to estimate the quality of life for people with asthma and specifically the loss in quality of life associated with an asthma-related crisis event (accident and emergency (A\&E) attendance or admission).
- Trial name
- NCT02771678
- Where
- 3 sites in United Kingdom
- Volunteers
- 121 people
- Sponsor
- University of East Anglia
Asthma
A Comparison of SYMBICORT® pMDI With Budesonide HFA pMDI in African American Subjects With Asthma.
The purpose of this study is to determine the effectiveness and safety of SYMBICORT® pMDI (a medication approved by the Food and Drug Administration, FDA) in the African American population.
- Trial name
- NCT00419952
- Testing
- Budesonide/formoterol (SYMBICORT) pMDI, Budesonide HFA pMDI
- Where
- 122 sites in United States
- Volunteers
- 742 people
- Sponsor
- AstraZeneca
Asthma
US PRECISION Implementation Study
The primary objective of this community program intervention study is to assess the process and potential benefits of integrating the AIRQ®, Asthma Checklist, and educational resources (PRECISION program) into clinical practice…
- Trial name
- NCT04891978
- Testing
- AIRQ, Asthma Checklist, PRECISION Program (Educational Resources)
- Where
- 13 sites in United States
- Volunteers
- 857 people
- Sponsor
- AstraZeneca
Bronchial Asthma
House Dust Mites Sensitization and Level of Asthma Control and Severity in Children
In this study we aimed to assess the clinical and laboratory profile of some Egyptian asthmatic children who are sensitized to house dust mites and determine the association of HDM sensitization and severity of asthma according…
- Trial name
- NCT04958616
- Testing
- Skin prick test.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University Children Hospital
Asthma
A Study of JNJ-38518168 in Symptomatic Adult Participants With Uncontrolled, Persistent Asthma
The purpose of this study is to evaluate the efficacy, safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of JNJ-38518168 compared with placebo in participants with persistent asthma that is inadequately…
- Trial name
- NCT01823016
- Testing
- JNJ-38518168
- Where
- 54 sites in United States, Canada and 4 more
- Volunteers
- 166 people
- Sponsor
- Janssen Research & Development, LLC
Asthma
A Study to Compare the Efficacy of Fluticasone Furoate/Vilanterol Inhalation Powder With Usual Inhaled Corticosteroids (ICS)/Long Acting Beta Agonists (LABA) in Persistent Asthma
The combination of FF, an ICS and VI, an orally inhaled LABA has been developed as a once-daily combination therapy for the long-term maintenance treatment of asthma in adults and children >=12 years of age.
- Trial name
- NCT02446418
- Testing
- Fluticasone Furoate, Vilanterol, Fluticasone propionate
- Where
- 93 sites in France, Germany
- Volunteers
- 423 people
- Sponsor
- GlaxoSmithKline
Asthma
A Study to Evaluate the Effects of Indacaterol Maleate (QAB149) as a New Formulation in the EPIC Test Fixture
This study will assess the pharmacodynamics, safety, tolerability and pharmacokinetics of indacaterol maleate (QAB149), administered via the EPIC test fixture.
- Trial name
- NCT01845623
- Testing
- QAB149 75 mg Concept 1, QAB149 75 mg Epic Test Fixture
- Sponsor
- Novartis Pharmaceuticals
Asthma
Study to Evaluate the Safety, Tolerability,Immunogenicity, and Pharmacokinetics of MEDI-528 in Healthy Adult Volunteers
Phase I study to evaluate the safety and tolerability of escalating single IV doses of MEDI-528.
- Trial name
- NCT00192296
- Testing
- MEDI-528 0.3 mg/kg, MEDI-528 1 mg/kg, MEDI-528 3 mg/kg
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Asthma
Evaluation of a Shared Decision Making Portal for Pediatric Asthma
This pilot intervention study will test the feasibility and acceptability and explore the outcomes of a primary care-based shared decision making (SDM) electronic medical record (EMR)-based portal that provides education, elicits…
- Trial name
- NCT01715389
- Testing
- MyAsthma Patient Portal
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Children's Hospital of Philadelphia
Asthma (Diagnosis)
Sustained Asthma Remission and Reduced Relapse Using a Comprehensive Management Strategy (SARRE-COMS)
The goal of this pilot clinical trial is to learn whether it is feasible to conduct a future larger trial of a comprehensive management strategy for adults with severe asthma who are starting biologic therapy.
- Trial name
- SARRE-COMS (NCT07816718)
- Testing
- Comprehensive Biomarker-Guided Management Strategy, Standard of Care
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Hana Serajeddini
Rhinovirus Infection in Asthma
Mechanisms of Interplay Between Allergy and Viruses in Asthma
The aim of this study is to investigate the mechanisms of interplay between allergy (IgE and Th2 mediated inflammation) and virus infection in the development of asthma, as well as the risk and severity of acute exacerbations of…
- Trial name
- NCT01773590
- Testing
- Rhinovirus Infection
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Vitamin D Deficiency
Effects of Vitamin D3 Supplementation on Antioxidant Enzymes Status in Vitamin D3 Deficient Asthma COPD Overlap (ACO) Patients
Asthma-COPD overlap (ACO) is a new entity in the world of respiratory ailments. The respiratory tract of these patients are continuously exposed to oxidants (due to cigarette smoking) causing oxidative stress.
- Trial name
- NCT03931889
- Testing
- Vitamin D3
- Where
- Bangladesh
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Allergic Asthma, Airway Remodelling
Eosinophil Induced Remodelling in Asthma
Asthma is a chronic, inflammatory disease of the lung characterized by intermittent airway obstruction, airway hyperresponsiveness, presence of activated inflammatory cells, inflammatory mediators, and airway structural changes.
- Trial name
- ERA (NCT02648074)
- Testing
- Bronchial challenge with allergen, Co-culture formation
- Where
- Lithuania
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Bronchial Asthma
Effects on Small Airways of Two Long-term Extrafine Treatments in Asthma
New formulations of extrafine particles of long acting beta-2 agonists+inhaled corticosteroids (LABA+ICS) are able to reach more peripheral regions of the lung.
- Trial name
- FORTINO (NCT01255579)
- Testing
- Salmeterol Fluticasone, formoterol - beclometasone
- Volunteers
- 10 people
- Sponsor
- Università degli Studi di Brescia
Severe Persistent Asthma
A National Program for Severe Asthma: The Canadian Severe Asthma Network
The Canadian Severe Asthma Network (CSAN) was developed to gain a better understanding of the clinical, environmental, socio-economic, work-related, and biological characteristics of severe asthmatics (SA) that may account for…
- Trial name
- CSAN (NCT00954850)
- Where
- Canada
- Sponsor
- University of Alberta
Rhinoconjunctivitis With or Without Allergic Asthma
Study to Assess the Safety and Effectiveness of Beltavac® Polymerized With Cat Dander
Non-interventional Study to Assess the Safety and Effectiveness Profile of a SCIT Therapy With Beltavac® Polymerized With Cat Dander in allergic patients
- Trial name
- NCT04207697
- Testing
- Beltavac® Polymerized with cat dander
- Where
- 7 sites in Spain
- Volunteers
- 34 people
- Sponsor
- Probelte Pharma S.L.U.
Asthma
Remote Use of the Asthma Control Test (ACT) to Improve Care of Children With Asthma
This study will assess whether adaption of the Asthma Control Test (ACT) and childhood Asthma Control Test (cACT) for mobile devices improves rate of completion and improves control of asthma in children and adolescents
- Trial name
- NCT03036982
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- Boston Children's Hospital
Allergic Rhinitis
Immunological Mechanisms of Oralair® in Patients With Seasonal Allergic Rhinitis
Allergic diseases represent a major health issue worldwide and epidemiological studies in Melbourne, Australia, have reported a high prevalence of rhinitis (hayfever) and atopy (genetic tendency to make allergy antibody) in Asian…
- Trial name
- NCT02014623
- Testing
- Grass pollen sublingual immunotherapy tablet, Control
- Where
- Australia
- Volunteers
- 51 people
- Sponsor
- Bayside Health
Asthma
Efficacy of Ciclesonide Versus Fluticasone Propionate in Patients With Mild to Moderate Asthma (12 to 75 y) (BY9010/M1-142)
The aim of the study is to compare the efficacy of ciclesonide versus fluticasone propionate on lung function, time to first asthma exacerbation, asthma symptoms, use of rescue medication, and quality of life in patients with…
- Trial name
- NCT00163423
- Testing
- Ciclesonide
- Where
- 51 sites in Austria, Canada and 3 more
- Volunteers
- 480 people
- Sponsor
- AstraZeneca
Asthma in Children
Traditional Chinese Medicine in Management of Childhood Asthma
Bronchial Asthma is a common childhood chronic disease characterized by chronic inflammation of the airways. Frequent relapse of asthma has serious impacts on the child's growth, impairs quality of life (QoL) and mortality…
- Trial name
- TraCMAst (NCT03645889)
- Testing
- PLTG
- Where
- Singapore
- Volunteers
- 130 people
- Sponsor
- KK Women's and Children's Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.