Clinical trials: asthma
Allergic Asthma, Allergy to House Dust
Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Mite Allergic Subjects With Asthma
This is a randomized, double blind, cross-over study designed to determine the concentration of airborne house dust mite allergen inducing bronchial response in asthmatic subjects allergic to mite, during allergen exposures in…
- Conditions
- Allergic Asthma, Allergy to House Dust, Allergy
- Trial name
- NCT04663880
- Testing
- Exposure to three concentrations of HDM allergen in EEC, Exposure to a single concentration of HDM allergen in EEC
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Alyatec
Asthma
Indirect Cost of Illness Study of Moderate and Severe Asthma in Quebec
Rationale Asthma is a chronic inflammatory disorder of the airways affecting persons of all ages and is recognized as one of the most common chronic diseases.
- Trial name
- NCT02153346
- Testing
- Valuation of lost productivity questionnaire, Work productivity and activity impairment questionnaire
- Where
- Canada
- Volunteers
- 101 people
- Sponsor
- GlaxoSmithKline
Chronic Rhinosinusitis (Diagnosis), Chronic Rhinosinusitis With Nasal Polyps
Tissue Immune Interaction in Nasal Polyposis
This is a cross-sectional study of up to 100 subjects who are undergoing clinically indicated sinus procedures to treat chronic rhinosinusitis.
- Conditions
- Chronic Rhinosinusitis (Diagnosis), Chronic Rhinosinusitis With Nasal Polyps, Asthma
- Trial name
- TIP (NCT04628442)
- Testing
- Sinonasal Debridement Procedure, Nasal Polyp Removal, Biopsy
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of California, San Francisco
Asthma
Onset of Action of Advair Hydrofluoroalkane (HFA) 115/21 in Comparison to Symbicort Pressurised Metered-Dose Inhalers (pMDI) 160/4.5 Measured by Impulse Oscillometry (IOS)
The objectives of this study are to measure Impulse Oscillometry (IOS) in patients with asthma extensively at baseline in patients with mild-to-moderate asthma, treated with as-needed short acting beta agonist only, to measure…
- Trial name
- NCT00867737
- Testing
- Advair HFA MDI 115/21, Symbicort 160/4.5 pMDI
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Allergy and Asthma Center of El Paso
Asthma
Long-term Safety and Efficacy Evaluation of Lunsekimig (SAR443765) in Adult Participants With Asthma
This is a phase 2, open-label extension study to evaluate the long-term safety and efficacy of lunsekimig in adult participants with asthma who have previously completed the parent studies.
- Trial name
- AIRPHRODITE (NCT06609239)
- Testing
- Lunsekimig
- Where
- 150 sites in United States, Argentina and 18 more
- Volunteers
- 900 people
- Sponsor
- Sanofi
Chronic Obstructive Pulmoriary Disease (COPD), Asthma
Clinical Study on the Treatment of Chronic Airway Diseases (Asthma, Chronic Obstructive Pulmonary Disease) with Shu Fei Tie
Conduct a multi-center, large-sample, randomized controlled clinical study of "winter disease being cared in summer" with Shu Fei Tie prevent recurrence of Asthma and COPD, scientifically evaluate the clinical efficacy and safety…
- Trial name
- NCT06691802
- Testing
- Shu Fei Tie
- Where
- China
- Volunteers
- 2,312 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Asthma
Efficacy and Safety Study of QAW039 in Patients With Severe Asthma Inadequately Controlled With Standard of Care Asthma Treatment.
This study aimed to determine the efficacy and safety of QAW039 150 mg and QAW039 450 mg, compared with placebo, when added to GINA (Global Initiative for Asthma) steps 4 and 5 standard-of- care (SoC) asthma therapy (GINA 2016)…
- Trial name
- NCT02555683
- Testing
- QAW039
- Where
- 234 sites in United States, Argentina and 25 more
- Volunteers
- 894 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
Redox Determinants of Severe Asthma (a Substudy of the Severe Asthma Research Program)
Hypotheses: 1) Airway pH regulation is abnormal in severe asthma; 2) In severe asthma, there is formation of cytotoxic nitrogen oxides and loss of beneficial nitrogen oxides in the airways
- Trial name
- SARP (NCT00590005)
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Emory University
COPD, Asthma
Efficacy of Education Programs in Patients With Chronic Airway Diseases
The objective of this study is to determine whether the systematic education on air way disease and inhalers in outpatient settings contributes to improve the quality of life.
- Trial name
- NCT02827929
- Testing
- Education
- Where
- South Korea
- Volunteers
- 285 people
- Sponsor
- Konkuk University Medical Center
Bronchial Asthma
Effect of Montelukast in Asthma in Children
This is 9 month, placebo-controlled, double blind, randomised trial using the oral leucotrienes receptor antagonist montelukast (5 mg) in 160 children with mild and moderate asthma age 6-14 year old, sensitive to house dust mite.
- Trial name
- NCT01266772
- Testing
- Montelukast sodium.
- Where
- Poland
- Volunteers
- 160 people
- Sponsor
- Medical University of Lodz
Asthma, Exercise-Induced
Montelukast Compared With Placebo and Salmeterol in Exercise-Induced Bronchoconstriction (0476-316)
To determine the effect of an approved medication being studied in support of a new approach in the prevention of exercise-induced asthma (a worsening of asthma caused by exercise, also known as exercise-induced bronchospasm), in…
- Trial name
- NCT00245570
- Testing
- Comparator: Montelukast, Comparator: Salmeterol
- Volunteers
- 47 people
- Sponsor
- Organon and Co
Atopic Dermatitis, Food Hypersensitivity
Use of Probiotic Bacteria in Prevention of Allergic Disease in Children 1999-2008
The aim of the study is to find out if allergic diseases can be prevented buy giving probiotic bacteria to pregnant mothers and their newborn infants
- Conditions
- Atopic Dermatitis, Food Hypersensitivity, Allergic Rhinitis, Seasonal, Allergic Conjunctivitis
- Trial name
- NCT00298337
- Testing
- Mixture of probiotic bacteria and prebiotic oligosaccharide
- Where
- Finland
- Sponsor
- University of Helsinki
Diabetes, Hypertension
Exploring Folk Health Practices in Latinos With Chronic Medical Conditions
This study will explore how culture influences the use of folk healing practices and medical services in Latinos with chronic medical conditions.
- Conditions
- Diabetes, Hypertension, Asthma, Heart Disease
- Trial name
- NCT00224237
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Weill Medical College of Cornell University
Bronchiolitis
The Bronchiolitis in Hospitalized Infants Study
The goal of this clinical trial is to determine whether it is possible to identify, enroll, and deliver the study intervention (the corticosteroid dexamethasone) in hospitalized infants with bronchiolitis.
- Trial name
- BroncHI (NCT05994183)
- Testing
- Dexamethasone Oral
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- IDeA States Pediatric Clinical Trials Network
Asthma in Children
Pediatric Glittre ADL-test in Children With Asthma
The aim of the study is to investigate reliability, validity, of the Glittre ADL Test in children with Asthma.
- Trial name
- NCT03985956
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Gazi University
Asthma
The Breathe Well Program for Adults With Asthma
The Breathe Well Study is a pragmatic, controlled trial to assess the effectiveness, cost-effectiveness, and implementation of the Breathe Well intervention, which combines evidence-based EHR and interactive behavior-change…
- Trial name
- NCT02761837
- Testing
- IVR call/text, Email
- Where
- United States
- Volunteers
- 14,978 people
- Sponsor
- National Jewish Health
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Asthma
Chronic Asthma Study in 2- to 5-Year-Old Patients (MK0476-072 )
A study in 2-5 year old children to evaluate the safety and tolerability of montelukast and placebo administered once daily at bed time.
- Trial name
- NCT00968201
- Testing
- montelukast sodium
- Volunteers
- 689 people
- Sponsor
- Organon and Co
ASTHMA, ALLERGIC RHINITIS
Hair Cortisol in Asthma or Allergic Rhinitis Treated With Topical Corticosteroids
The purpose of this study is to prospectively examine the relation between topical corticosteroid use and hair cortisol concentration, among patients with moderate persistent asthma or allergic rhinitis.
- Trial name
- NCT01839851
- Testing
- Treatment with any inhaled corticosteroid, Treatment with any intranasal glucocorticoid
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Meir Medical Center
Severe Asthma
Characterization and Clinical Outcomes of Severe Asthma Patients in Israel Treated With Benralizumab (SAIL-B)
A retrospective, observational, one arm, single country study, using the computerized database of Maccabi Health Services (MHS).
- Trial name
- SAIL-B (NCT07218172)
- Where
- Israel
- Volunteers
- 197 people
- Sponsor
- AstraZeneca
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