Clinical trials: bipolar
Bipolar Disorder Family Members
A Psychoeducation Intervention for Caregivers of Patients With Bipolar Disorder
Bipolar disorder is a debilitating chronic illness characterized by periods of elation and depression. Since deinstitutionalization of the mentally ill over 40 years ago, families have become major caregivers for patients with…
- Trial name
- NCT02446509
- Testing
- Psychoeducation, Psychoeducation - Delayed
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Bipolar Disorder
Study of Aripiprazole (Abilify) in Children With Symptoms of Mania
The purpose of this study is to look at the safety and effectiveness of aripiprazole (abilify) in children with bipolar disorder and to examine whether or not patients that respond to initial mood stabilization benefit from…
- Trial name
- NCT00194077
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Major Depressive Disorder, Mood Disorders
Psychobiological Markers to Improve Diagnosis and to Predict Affective Episodes in Bipolar Disorder
This trial has two studies. In study 1, the investigators will explore the relationships between three psychobiological factors (sleep patterns, motor activity, and decision-making ability).
- Conditions
- Major Depressive Disorder, Mood Disorders, Bipolar Disorder (BD)
- Trial name
- MoodCatcher (NCT07427966)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Depression, Bipolar Disorder
Neuro-computational Study of Thymic Fluctuations in Mood Disorders
Depression and bipolar disorder are frequent, debilitating conditions. Both are thought to be primarily caused by an impaired regulation of mood, which is why they are sometimes referred to as "mood disorders".
- Conditions
- Depression, Bipolar Disorder, Recurrent Depression, Mood Disorders
- Trial name
- MOODELING (NCT07033923)
- Testing
- Brain magnetic resonance imaging (MRI) with structural (anatomical) and functional sequences (optional), Computerized cognitive tests, Daily longitudinal monitoring by mobile MOODELING application
- Where
- 2 sites in France
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Bipolar Disorder, NOS
Brain Connectivity and Mindfulness Training in Youth With Bipolar Disorder Not Otherwise Specified (NOS)
The investigators propose to study 30 adolescents with bipolar disorder, not otherwise specified (BD NOS) and a family history of Bipolar I Disorder (BD) at baseline with rs-fMRI (functional magnetic resonance imaging) and…
- Trial name
- NCT02435225
- Testing
- Mindfulness Based Stress Reduction for Teens Group
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Stanford University
Educational Problems, Anxiety and Fear
Standard Patient Simulation in Nursing Students' Approach Toward Patients With Bipolar Disorder
The study was conducted to determine the effect of the simulation method with the participation of standardized patients towards the patients suffering from bipolar disorder to benefit the education of the psychiatry nursing…
- Conditions
- Educational Problems, Anxiety and Fear, Nurse-Patient Relations
- Trial name
- NCT04027933
- Testing
- Education Based on Standard Patient Simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Bipolar Disorder (BD), Bipolar Disorder (BPD)
Testing a New Gold Nanoparticle-Based Lithium Delivery Method for Bipolar Disorder in Laboratory Models
This preclinical translational study aims to evaluate a new method of delivering lithium using gold nanoparticles for the treatment of bipolar disorder.
- Trial name
- GLAD (NCT07732933)
- Testing
- Peripheral blood sampling for PBMC isolation
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Bipolar Disorder
Culturally Adapted Psychoeducation (CaPE) for Bipolar Disorders in Nigeria
Bipolar disorders are chronic mental health disorders that often result in functional impairment, constituting a significant disease burden.
- Trial name
- NCT05721196
- Testing
- Culturally adapted Psychoeducation (CaPE), Treatment as Usual (TaU)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Major Depressive Disorder, Bipolar Disorder, Mixed
Chinese Longitudinal and Systematic Study of Bioplar Disorder
Affective disorders (mainly including major depressive disorder and bipolar disorder) are common, chronic and highly disabling mental disorders, which lack of objective biological markers.
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Mixed, Affective; Disorder, Organic
- Trial name
- CLASS-BD (NCT05480150)
- Testing
- Escitalopram Oxalate Tablets, Quetiapine Fumarate Tablets, Lurasidone
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Bipolar Disorder Depression, Major Depression
AI-based Multi-center Research on Identification/Classification/Aided Diagnosis of Mood Disorder
At present, diagnosis and recognition of depression and bipolar disorder are mainly based on subjective evidence such as clinical interview and scale evaluation.
- Trial name
- NCT05608135
- Where
- China
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Mental Illness Persistent, Cardiovascular Prevention
Cardiac Rehabilitation for Cardiovascular Risk Reduction in People With Severe and Persistent Mental Illness
The goal of this prospective, randomized trial is to explore the link between cardiovascular disease and mortality in individuals with severe and persistent mental illness (SPMI).
- Trial name
- NCT05659498
- Testing
- Cardiac Rehabilitation Program
- Where
- Canada
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Bipolar Disorder
Study of the Genetic and Environmental Factors of Vulnerability in Bipolar Disorders
Bipolar disorder is a complex, multifactorial disorder with the intervention of genetic vulnerability factors. To help the identification of these genetic factors and to improve genotype-phenotype correlation, the identification…
- Trial name
- GAN (NCT02627404)
- Testing
- Blood sample, actometer
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Psychosis
Immune Mechanisms of Antipsychotic Treatment Response
The aim of this study is to investigate the role of the immune system in psychotic symptoms and their response to treatment. The investigators will collect blood and cerebrospinal fluid samples from participants with psychosis…
- Trial name
- IMAT (NCT06687694)
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- King's College London
Bipolar Disorder and Major Depressive Disorder
Social Cognition, Memory, and Executive Functions in Bipolar Disorder and Major Depressive Disorder
Bipolar disorder (BD) are common psychiatric disorders often misdiagnosed, leading to delayed treatment. Even during stable phases, individuals with bipolar disorder experience residual cognitive impairments that affect their…
- Trial name
- COMET (NCT06740331)
- Testing
- Analysis of social cognition, memory functioning, and executive functioning processes
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Schizophrenia, Bipolar Disorder
Time,Self and Spontaneous Mental Activities in Patients With Psychotic Disorders
The main purpose of the study is to examine to which extent abnormalities in the dynamics of neural activities observed in patients with psychosis is related to difficulties at ordering simple visual stimuli and/or personal…
- Trial name
- Self and Time (NCT02765880)
- Testing
- fMRI, EEG
- Where
- France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Schizophrenia, Bipolar Disorder
CSP #572 - Genetics of Functional Disability in Schizophrenia and Bipolar Illness
The purpose of this study is to detect genetic associations for the development of schizophrenia (SZ) and bipolar illness (BP) by comparing Veterans with these diseases to "psychiatrically healthy" Veterans from Veterans Health…
- Trial name
- NCT01149551
- Where
- 25 sites in United States
- Volunteers
- 9,356 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Healthy Volunteers, Generalized Anxiety Disorder (GAD)
A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of ABBV-932 in Healthy Adult Participants, Participants With Generalized Anxiety Disorder (GAD) and Participants With Bipolar Disorder (BPD)
The purpose of this study is to assess the pharmacokinetics, safety, and tolerability following multiple ascending oral doses of ABBV-932 or placebo in healthy adult participants, participants with Generalized Anxiety Disorder…
- Conditions
- Healthy Volunteers, Generalized Anxiety Disorder (GAD), Bipolar Disorder (BPD)
- Trial name
- MAD (NCT06024239)
- Testing
- ABBV-932
- Where
- 3 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AbbVie
Bipolar TURP , Laser Enucleation in Management of Enlarged Prostate
Bipolar Versus Laser Enaculation of Prostate for >80gram Prostate .
Transurethral resection of the prostate (TURP ) still the gold standerad for surgical management of enlarged prostate .However , many minimally invasive procedures are now in the comparative track with Bipolar resection as Laser…
- Trial name
- NCT05784181
- Testing
- bipolar transurethral resection and Laser enaculation by holmium: YAG laser
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Bipolar Disorder, Bipolar I Disorder
Using Neuroplasticity-Based Computerized Training to Improve Emotion Regulation in Bipolar Disorder (BRAINS)
The goal of this study is to evaluate the feasibility and potential benefit of a behavioral intervention designed to improve emotion regulation in individuals with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar I Disorder, Bipolar Affective Disorder, Bipolar Disorder I
- Trial name
- BRAINS (NCT05683431)
- Testing
- Cognitive Control of Emotion (CCE) Training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Bipolar Disorder
A Study of LY2979165 in Healthy Subjects
This is a two part study. Part A is a multiple-ascending dose study in up to 6 different groups of healthy subjects, with approximately 12 subjects in each of the groups.
- Trial name
- NCT01383967
- Testing
- LY2979165
- Where
- Singapore
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company