Clinical trials: bipolar
Bipolar Disorder
Prophylactic Effect of Lamotrigine Compared With Lithium in Bipolar Disorder
The purpose of this study is to compare lamotrigine with lithium in the long term treatment of bipolar disorder in terms of new episode preventive potentials.
- Trial name
- NCT00226135
- Testing
- lithium or lamotrigine
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Aarhus
Bipolar Disorder
Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depression Episode
The purpose of this study is to evaluate flexible doses (5-30mg) of aripiprazole versus placebo in patients with bipolar depression.
- Trial name
- NCT00080314
- Testing
- Aripiprazole
- Where
- 28 sites in United States
- Volunteers
- 400 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Mental Illness, Schizophrenia
Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use
Severe mental illness (SMI) refers to the most burdensome psychiatric conditions. The need to pre-empt the onset of SMI is pressing because once SMI develops, quality of life is poor and available treatments have limited…
- Conditions
- Mental Illness, Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- IMAGINE (NCT03601026)
- Testing
- Genetic counselling
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Nova Scotia Health Authority
Depression; Bipolar Disorder
Comparing Different Patterns of rTMS in Major Depression
This trial will compare the trajectories of improvement for three different patterns of twice-daily rTMS in major depression: two daily sessions of dorsomedial prefrontal rTMS delivered at 0 min vs. 30 min vs. 60 min intervals.
- Trial name
- NCT02778035
- Testing
- Dorsomedial prefrontal rTMS
- Where
- 2 sites in Canada
- Volunteers
- 180 people
- Sponsor
- University Health Network, Toronto
Bipolar Disorder, Major Depressive Disorder
Early Intervention for Youth at Risk for Bipolar Disorder
Children or teens with mood swings or depression who have a parent with bipolar disorder are at high risk for developing bipolar disorder themselves.
- Trial name
- NCT01483391
- Testing
- Enhanced Care, Family-Focused Treatment
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of California, Los Angeles
Mood Disorders, Prodromal Symptoms
MBCT and CBT for Youth at High Risk for Mood and Psychotic Disorders: a Randomized Controlled Trial
The present study is a randomized controlled trial comparing the efficacy and acceptability of CBT and MBCT group-based interventions adapted for young people at elevated risk for mood or psychotic disorder onset or relapse.
- Conditions
- Mood Disorders, Prodromal Symptoms, Bipolar Disorder, Parents
- Trial name
- NCT05070052
- Testing
- cognitive behavioral therapy, mindfulness-based cognitive therapy
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of California, Los Angeles
Bipolar II Disorder
Seroquel in the Treatment of Dysphoric Hypomania in Bipolar II
1. The primary objective of this study is to examine the efficacy of quetiapine (Seroquel) in treatment of dysphoric hypomania in patients with Bipolar II disorder. 2.
- Trial name
- NCT00186043
- Testing
- Quetiapine/Seroquel
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Stanford University
Bipolar Spectrum Disorder
Client-led Online Therapy for People Diagnosed With Bipolar Disorder
The study aims to investigate the use of Method of Levels therapy (MOL) delivered online via videoconferencing for people who have received a diagnosis of a bipolar spectrum disorder.
- Trial name
- NCT04859647
- Testing
- Method of Levels Therapy
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Manchester
Major Depressive Disorder, Bipolar Disorder
Multi-factor Model Constraction for Early Warning and Diagnosis of MDD
Current research on the pathogenesis of depression shows that imbalanced inflammatory factors are closely related to Major Depressive Disorder(MDD).
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Omega-3 Fatty Acids
- Trial name
- NCT05529576
- Testing
- Omega 3 fatty acid
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Bipolar Depression
Exploring the Effects of Coenzyme Q10 on Bioenergetics Metabolism in Geriatric Bipolar Depression
The investigators propose to study and compare measures of brain energy metabolism in geriatric bipolar individuals and healthy older adults.
- Trial name
- NCT01390389
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Bipolar Disorder
Evaluation of Brain MRI and Clinical Characteristics of Adolescents With Bipolar Disorder and Children of Parents With Bipolar Disorder
Genetic transition is important in the etiology of bipolar disorder (BD). So, evaluation of children of BD parents and diagnosed with and BD children whether or not brain has affected zones.
- Trial name
- NCT01678989
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Turkish Psychiatry Association
Depression, Stress Disorders, Post-traumatic
Cornerstone Program for Transition-Age Youth Study Protocol for a Randomized Controlled Trial
The purpose of this study is exploring a theoretically guided intervention, Cornerstone, which provides system 'boundary-spanning' services, including therapeutic services and mentorship, to transition-age youth with mental…
- Conditions
- Depression, Stress Disorders, Post-traumatic, Bipolar Disorder
- Trial name
- NCT02696109
- Testing
- Treatment As Usual, Cornerstone
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- New York University
Bipolar Disorder (BD), Organoids
Analysis of Early Neurodevelopmental Alterations in Bipolar Disorder Based on Cortical Organoid Models
Demonstrate the existence of neurodevelopmental alterations in organoids derived from samples of patients with bipolar disorder (BD) with a neurodevelopmental (ND) component, compared with patients with bipolar disorder (BD)…
- Conditions
- Bipolar Disorder (BD), Organoids, Neurodevelopmental Conditions
- Trial name
- BIPODEV (NCT06968598)
- Testing
- blood sample
- Volunteers
- 10 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Bipolar Disorder, Depression
Effectiveness of Cognitive Behavioral Therapy for Treating Depression in People With Bipolar I Disorder
This study will compare the effectiveness of cognitive behavioral therapy versus supportive psychotherapy in decreasing depression in people with bipolar disorder.
- Trial name
- NCT00595387
- Testing
- Supportive Psychotherapy, Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Bipolar Disorder, Type II
Internet-based Cognitive Behaviour Therapy (CBT) for Persons Diagnosed With Bipolar II
The aim of the study is to test the feasibility and acceptability of internet-based Cognitive Behaviour Therapy (CBT) for persons diagnosed with bipolar disorder, type II.
- Trial name
- NCT01742351
- Testing
- Guided internet-based cognitive behavior therapy
- Where
- Sweden
- Volunteers
- 7 people
- Sponsor
- Örebro County Council
Bipolar Disorder
Far Infrared Radiation Treatment for Bipolar Condition
A preliminary study to determine the possibility of using far infrared radiation for the treatment of the Bipolar Condition
- Trial name
- NCT00573196
- Testing
- Far infrared
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- GAAD Medical Research Institute Inc.
Bipolar Disorder
Valproic Acid Sodium Salt in Bipolar Disorder
To determine the total and local gray matter volumes, and N-acetyl aspartate (NAA) levels in patients with bipolar disorders who are within euthimic, depressive or manic/hypomanic period and who are not taking drug; To…
- Trial name
- NCT00431522
- Testing
- Valproic acid, sodium salt
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Sanofi
Major Depression, Schizophrenia
Proactive Psychiatry Consultation for Patients With Cancer and Severe Mental Illness
Individuals with severe mental illness (SMI) including schizophrenia and bipolar disorder are dying younger than the general population; cancer is a leading cause of death in this population.
- Conditions
- Major Depression, Schizophrenia, Bipolar Disorder, Lung Cancer
- Trial name
- NCT02594696
- Testing
- Proactive Psychiatry Consultation (PPC)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Schizophrenia, Bipolar Disorder
A Biological Signature for the Early Differential Diagnosis of Psychosis
Schizophrenia (SZ) and mood disorders (BD, MDD) are among the most disabling disorders worldwide, with a relevant social, functional, and economic burden.
- Conditions
- Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT06515522
- Testing
- differential diagnosis
- Volunteers
- 1,850 people
- Sponsor
- IRCCS San Raffaele
Bipolar Disorder
Effects of Psycho-education of Patients With Bipolar Disorder
The purpose for this study is to determine whether psycho-education in groups is more effective than individual psycho-education for patients with bipolar disorder.
- Trial name
- NCT00159562
- Testing
- individual education, Group education
- Where
- Norway
- Volunteers
- 85 people
- Sponsor
- Norwegian University of Science and Technology
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