Clinical trials: copd or chronic obstructive
Asthma
A Single Centre Study in Healthy Volunteers to Optimise the Rotacap Formulation and ROTAHALER Device for Delivery of Fluticasone Propionate/Salmeterol
The purpose of this study is to optimise the device and/or formulation of the Fluticasone propionate (FP)/salmeterol (SALM) unit dose powder inhaler (Rotahaler) to achieve drug delivery characteristics comparable to the…
- Trial name
- NCT01540708
- Testing
- SERETIDE Rotacaps, SERETIDE Diskus
- Where
- Australia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pulmonary Disease, Chronic Obstructive
Effect of GSK704838 In Healthy Volunteers
GSK704838C is a potent, pan-active mAChR antagonist, which is being developed for once-daily treatment of chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00539825
- Testing
- GSK704838
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Orthopedic Disorder, Neurologic Disorder
Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions
To determine the safety and efficacy of Amniotic and Umbilical Cord Tissue for the treatment of the following condition categories: Orthopedic, Neurologic, Urologic, Autoimmune, Renal, Cardiac and Pulmonary Conditions.
- Conditions
- Orthopedic Disorder, Neurologic Disorder, Urologic Diseases, Erectile Dysfunction
- Trial name
- NCT03899298
- Testing
- Amniotic and Umbilical Cord Tissue Procedure
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- R3 Stem Cell
COPD
Chronic Obstructive Pulmonary Disease (COPD) Biomarker Identification Study
Chronic obstructive pulmonary disease (COPD) is a common inflammatory disease of the airway affecting approximately 10% of individuals aged 40 years or more with a smoking history.
- Trial name
- NCT01780298
- Where
- United Kingdom
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Pulmonary Disease, Chronic Obstructive
A Study to Assess the Systemic Exposure, Systemic Pharmacodynamics and Safety and Tolerability of FluticasoneFuroate, Umeclidinium and Vilanterol in Healthy Subjects
This is a double-blind, single dose (four inhalations), four-way cross over study in healthy subjects that will assess the systemic pharmacokinetics (PK) and systemic pharmacodynamics (PD) of Fluticasone Furoate, (FF)…
- Trial name
- NCT01691547
- Testing
- UMEC /VI, UMEC, VI
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease (COPD)
Pulmonary Vascular Impairment in Chronic Obstructive Pulmonary Disease (COPD) Assessed by MRI
Chronic Obstructive Pulmonary Disease (COPD) is a highly prevalent pulmonary disease providing major morbidity and mortality. Bronchial obstruction is the cornerstone in assessment of the disease whereas associated pulmonary…
- Trial name
- PulmoVasc (NCT04126616)
- Testing
- chest Magnetic Resonance Imaging (MRI) using Gadolinium-based contrast agent
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Diabetes, Chronic Kidney Diseases
Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)
This research programme seeks to combine the resources of NHS primary care, with the leading spectroscopic work in low-magnetic fields of the Wilson Group (Nottingham Trent University) to demonstrate the potential for benchtop…
- Conditions
- Diabetes, Chronic Kidney Diseases, Cancer, Bowel Disease
- Trial name
- BRANCH-P (NCT05473325)
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Willows Health
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Canadian Consortium on Airway Mucus Occlusions in Asthma, COPD and Chronic Cough
Chronic lung diseases affect one in five Canadians, causing symptoms such as cough, breathlessness, and wheeze. Despite advancements in medical care, these conditions not only impact individuals and their close circles but also…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Chronic Cough (CC)
- Trial name
- CANMuc (NCT06858748)
- Testing
- Observational
- Where
- 7 sites in Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- McMaster University
Chronic Obstructive Pulmonary Disease, Lung Diseases
Supplemental Selenium and Vitamin E and Pulmonary Function
To test whether supplementation with selenium and/or vitamin E affects pulmonary function.
- Conditions
- Chronic Obstructive Pulmonary Disease, Lung Diseases, Lung Diseases, Obstructive
- Trial name
- NCT00063453
- Testing
- Vitamin E, Selenium
- Volunteers
- 2,920 people, healthy volunteers welcome
- Sponsor
- Cornell University
Atrophy, Muscular
31P MRS Ischaemic Exercise Optimisation and COPD
An MRI study to develop a reliable methodology for 31P MRS ischaemic exercise in order to obtain a consistent standard of measurement of muscle metabolism while maintaining an acceptable level of subject comfort and use optimised…
- Trial name
- NCT01476072
- Testing
- MRI scan
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Bronchiectasis Adult, Chronic Obstructive Pulmonary Disease
The Characteristic of Airway Microbiome Profiling of COPD-bronchiectasis Overlap Patients and Its Association With Acute Exacerbation
The overlap between chronic obstructive pulmonary disease (COPD) and bronchiectasis is a neglected area of research, and it is not covered by guidelines for clinical practice.
- Conditions
- Bronchiectasis Adult, Chronic Obstructive Pulmonary Disease, Overlap, Microbiome
- Trial name
- NCT04865861
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Guangzhou Medical University
COPD, Cystic Fibrosis
Hyperpolarized Noble Gas MR Imaging for Pulmonary Disorders
The purpose of this study is to test the efficacy of Hyperpolarized Helium-3 gas in MR imaging in COPD, asthmatics, CF and healthy volunteers.
- Conditions
- COPD, Cystic Fibrosis, Asthma, Healthy
- Trial name
- NCT00846573
- Testing
- Hyperpolarized Helium-3
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Chronic Obstructive Pulmonary Disease
USCOM For Assessing Patients With COPD
Objective The Ultrasonic Cardiac Output Monitor (USCOM) is a non-invasive, quantitative method for measuring and monitoring cardiovascular haemodynamic parameters in patients. The aims of this study are: 1.
- Trial name
- NCT02329522
- Testing
- Ultrasonic Cardiac Output Monitor, Spirometry
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
COPD
Complexity of the Airflow in COPD
Recently, there has been a growing interest in the study of nonlinear dynamics as a methodology for complementary analysis to characterize the respiratory pattern. These methods are well established in studies of heart rate.
- Trial name
- NCT01888705
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
COPD
The Prevalence of Chronic Pain in COPD and Its Clinical Implications
This study explores the prevalence of chronic pain in individuals with COPD compared to healthy controls and examines the clinical implications of pain on symptoms associated with COPD, psychological effect and physical activity.
- Trial name
- NCT05366946
- Testing
- Prevalence study
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- West Park Healthcare Centre
Pulmonary Disease, Chronic Obstructive
A Study to Assess the Effects of Repeat Doses of Fluticasone Furoate and GW642444M Combination in Healthy Subjects and in Subjects With Severe Impairment.
This study will assess the saftey of giving fluticasone furoate 200mcg/GW642444M 25mcg once daily for 7 days to patients with severe renal imparement.
- Trial name
- NCT01266980
- Testing
- Inhaled FF/ GW642444M (200/25mcg)
- Where
- Czechia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
COPD, Asthma
Assessment of Rheological Parameters of Human Sputum.
This is a proof of concept study. The aim of this study is to assess a device measuring rheological properties of human sputum of four populations : 10 patients with Broncho Chronic Obstructive Pulmonary Disease (COPD) 10…
- Conditions
- COPD, Asthma, Cystic Fibrosis
- Trial name
- RHEOMUCO (NCT02682290)
- Testing
- Expectoration and measurement of sputum rheological properties
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
COPD
Bronchial Obstruction in Dairy Farmers
Chronic Obstructive Pulmonary Disease (COPD) is a major public health problem and is expected to become the 3rd leading cause of death globally by 2020. The main risk factor is tobacco.
- Trial name
- BPCO Airbag (NCT03654469)
- Testing
- questionnaires and electronic mini-spirometry
- Where
- France
- Volunteers
- 1,247 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Salmeterol Effect Against an Acute Alveolar Fluid Clearance Challenge Secondary to Lung Fluid Overload in COPD Patients, Chronic Obstructive Pulmonary Disease
Effect of Salmeterol on Fluid Clearance From Alveolar-Capillary Membrane in COPD Patients
The cardiovascular component associated with COPD plays a major role in prognosis of the disease, being responsible of 25% of the deaths.
- Conditions
- Salmeterol Effect Against an Acute Alveolar Fluid Clearance Challenge Secondary to Lung Fluid Overload in COPD Patients, Chronic Obstructive Pulmonary Disease, Bronchodilator Agents, Salmeterol
- Trial name
- SALM1 (NCT01271556)
- Testing
- Salmeterol, saline infusion (0.9 per cent sodium chloride)
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Milan
Anesthesia
The Effect of Sevofluorane on Wash-out Time in COPD
COPD (Chronic obstructive disease ) is a condition of respiratory system failure seen occasionally in elderly patients of society. Sevofluorane is a safe, volatile anesthetic used considerably widely all over the world.
- Trial name
- washout (NCT02209883)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duzce University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.