Clinical trials: copd or chronic obstructive
Lung Diseases, Obstructive
Costs and Effects of Three Modes for Disease Management of Chronic Obstructive Pulmonary Disease in General Practice
In this randomized controlled trial, three contemporary modes for chronic obstructive pulmonary disease (COPD) management in Dutch general practices are compared for costs and effects: usual general practitioner (GP) care (at…
- Trial name
- NCT00128765
- Testing
- an integrated self-management education program, regular practice nurse review (monitoring controls), care at initiative of the patient (usual GP care)
- Where
- Netherlands
- Volunteers
- 165 people
- Sponsor
- Radboud University Medical Center
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
A Thorough QT (TQT) Study of CHF5993 pMDI in Healthy Volunteers (HV)
The purpose of this study is to evaluate the potential for cardiac repolarization, according to electrocardiographic monitoring (including QT and QTc intervals), of two dose levels of CHF5993 pMDI (beclomethasone…
- Trial name
- NCT05830071
- Testing
- CHF5993, CHF5259, Moxifloxacin 400mg
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Pulmonary Disease, Chronic Obstructive
Ease of Use and Correct Use Study of Placebo ELLIPTA® Inhaler in COPD Subjects
Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease characterized by airflow limitation that is not fully reversible.
- Trial name
- NCT02586493
- Testing
- Questionnaire
- Where
- 16 sites in United States
- Volunteers
- 278 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Diseases
Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal
Chronic Obstructive Pulmonary Disease [COPD] is a major cause of chronic morbidity and mortality worldwide. COPD is characterized by persistent progressive airflow limitation that adversely affects the ventilation/perfusion (V/Q)…
- Trial name
- COPD (NCT03461328)
- Testing
- Magnesium Sulphate
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Pulmonary Disease, Chronic Obstructive
Study to Assess GW642444 in Asthma Patients
This is a study of GW642444M, a long-acting beta 2 specific agonist. This study will examine GW642444M via the inhaled route and will assess the efficacy, safety, tolerability, pharmacodynamics and pharmacokinetics of a single…
- Trial name
- NCT00381667
- Testing
- GW642444M, GW642444H
- Where
- 2 sites in Australia, New Zealand
- Volunteers
- 14 people
- Sponsor
- GlaxoSmithKline
COPD
Interest of Performing Two 6-minute Walk Tests at the End of a Pulmonary Rehabilitation Program, in COPD Patients.
In pulmonary rehabilitation, the 6-Minute Walk Test (6MWT) is essential to assess the effects of the program on patients' health. Current guidelines don't recommend to perform two 6MWT at the end of pulmonary rehabilitation.
- Trial name
- 2-TM6 (NCT05850299)
- Where
- France
- Volunteers
- 176 people
- Sponsor
- University Hospital, Brest
Pulmonary Disease, Chronic Obstructive
Tiotropium Bromide Alone vs Tiotropium Bromide and Formoterol Fumarate in Subjects With COPD (Study P04272)
This study is being conducted to determine if the co-administration of formoterol fumarate and tiotropium bromide is more effective than the use of tiotropium bromide alone in patients with COPD.
- Trial name
- NCT00139932
- Testing
- formoterol fumarate
- Volunteers
- 255 people
- Sponsor
- Merck Sharp & Dohme LLC
Chronic Obstructive Pulmonary Disease (COPD)
Changes in Cardiac Function in COPD Patients After Administration of Budesonide/Formoterol (Symbicort®) Versus Placebo
To investigate whether Budesonide/Formoterol (Symbicort ®) therapy can improve heart function at rest by decreasing lung hyperinflation in patients with COPD (Chronic Obstructive Pulmonary Disease).
- Trial name
- AZCO (NCT01760304)
- Testing
- Budesonide / Formoterol
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Brigham and Women's Hospital
Chronic Obstructive Pulmonary Disease (COPD), Preserved Ratio Impaired Spirometry (PRISM)
Comparison of Clinical Status of Individuals With COPD and Preserved Ratio Impaired Spirometry
Despite the globally varying high prevalence rate of the PRISm phenotype, there are no guidelines for its diagnostic evaluation and management.
- Trial name
- NCT06682832
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Pulmonary Disease, Chronic Obstructive, Asthma COPD
Impact of a Mobile Phone and Educational Intervention
The purpose of this pilot study was to: 1. partner with African American churches to increase awareness of COPD. 2. use a community-based approach to facilitate early detection of COPD in the church setting.
- Trial name
- NCT06878898
- Testing
- Education and mobile phone text-messaging, Education only
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Kent State University
Chronic Obstructive Pulmonary Disease (COPD)
Chronic Effect of Whole-body Electrical Stimulation in COPD Patients
Randomized clinical trial. Patients with chronic obstructive pulmonary disease (COPD) GOLD III or IV will undergo 16 sessions of Whole-body Electrical Stimulation (WB-EMS) or pulmonary rehabilitation (PR), twice a week.
- Trial name
- NCT06761963
- Testing
- Whole-body electrical stimulation, Rehabilitation
- Volunteers
- 16 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Respiratory Disease
Manual Diaphragm Release on Stepping Reaction Time in Chronic Obstructive Pulmonary Disease
Finding the effect of diaphragm release exercises on stepping reaction time and balance in patients with chronic obstructive pulmonary disease patients.
- Trial name
- NCT06455033
- Testing
- Manual Diaphragm Release Technique, Breathing Exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
COPD
Physiotherapy in Patients With Stable Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is a lung disease that is characterized by incompletely reversible airflow obstruction. It is projected to be the fifth leading burden of disease worldwide by the year 2020.
- Trial name
- NCT02517411
- Testing
- Standard care, Physiotherapy added to standard care
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Granada
Chronic Obstructive Pulmonary Disease, Dyspnea
Muscle Training Effectiveness in the Degree of Dyspnea and Aerobic Capacity in COPD
Objective: To estimate the effectiveness of muscle training, the degree of dyspnea and aerobic capacity in patients over 50 with COPD, in a health care institution provider in Antioquia.
- Trial name
- NCT01452932
- Testing
- Physiotherapy, Yoga
- Volunteers
- 44 people
- Sponsor
- CES University
Lung Transplant
Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients
The purpose of this study is to see if taking the study drug, Belumosudil, for 52 weeks in addition to your usual care and medication, will prevent Chronic Lung Allograft Dysfunction (CLAD) in participants who have a lung biopsy…
- Trial name
- CLAD (NCT06476132)
- Testing
- Belumosudil
- Where
- 12 sites in United States, Canada
- Volunteers
- 234 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pulmonary Disease, Chronic Obstructive
Venovenous CO2 Removal (VVCO2R) in Patients With COPD and Acute Respiratory Failure
The purpose of this study to determine the safety and effectiveness of a mechanical device to remove carbon dioxide from the blood of patients with chronic obstructive pulmonary disease (COPD)when they are hospitalized in the…
- Trial name
- VVCO2R (NCT00594009)
- Testing
- Venovenous CO2 Removal (VVCO2R) in COPD
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Chronic Obstructive Pulmonary Disease (COPD), Obesity With a BMI Greater Than 30
Interest of Hypnosis When Setting up Non-invasive Ventilation in a Conscious Patient With COPD and/or Obesity With a BMI Greater Than 30, Suffering Fromacute Respiratory Distress in Adult Intensive Care
Discomfort during respiratory decompensation of a patient with chronic obstructive pulmonary disease (COPD) and/or obesity with a BMI greater than 30, in intensive care and the establishment of non-invasive ventilation (NIV) is…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Obesity With a BMI Greater Than 30, Acute Respiratory Distress in Adult Intensive Care
- Trial name
- HYVIR (NCT04220463)
- Testing
- Hypnosis + NIV, NIV
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Healthy, COPD
Effects of BFR Interventions in Healthy Individuals and Individuals With COPD
The purpose of the study is to investigate the effect of different blood flow restriction (BFR) interventions on muscle function and adaptations both in healthy well-trained individuals and individuals diagnosed with COPD.
- Trial name
- NCT05734534
- Testing
- BFR during training, BFR during rest
- Where
- Denmark
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Asthma, COPD
Repeat Emergency Department Visits Among Patients With Asthma and COPD
The purpose of the proposed study is to determine whether the addition of inhaled corticosteroids to treatment with oral corticosteroids and albuterol would reduce repeat emergency department (ED) visits among patients treated…
- Trial name
- NCT02499887
- Testing
- beclamethasone dipropionate, albuterol, Prednisone
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- State University of New York at Buffalo
Chronic Obstructive Pulmonary Disease
A Clinical Trial Comparing TQC3927 Inhaled Powder With Glycopyrronium Bromide and Formoterol Inhaled Aerosol (Biovoping® Lingchang®) for the Treatment of Chronic Obstructive Pulmonary Disease
This is a multicenter, randomized, open-label, positive-drug controlled study designed to evaluate the preliminary efficacy and safety of different doses of TQC3927 inhaled powder for short-term treatment of patients with chronic…
- Trial name
- NCT07633314
- Testing
- TQC3927 inhalation aerosol, Glyceryl bromide/formoterol inhalation aerosol
- Where
- 16 sites in China
- Volunteers
- 90 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
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