Clinical trials: fMRI
Vision Disorders
Modification in Cortical Activation in Pseudophakic Patients With Visual Difficulties After a Multifocal Implantation
This study will highlight differences in cortical activation between asymptomatic and symptomatic patients.
- Trial name
- PlainteIMF (NCT02529098)
- Testing
- fMRI
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Major Injury
Perioperative Research Into Memory: Cognitive Outcome Following Major Burns
The long term survival of patients who require admission to critical care (CC) following a major burn injury (MBI) continues to improve with advanced clinical management.
- Trial name
- PRiMe (NCT03470844)
- Testing
- Face-to-face neurocognitive tests, Psychological screening, fMRI
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Functional Movement Disorders
Brain Activity in People With Functional Movement Disorders
This study will use functional MRI (fMRI, a technique that shows what areas of the brain are active when performing different mental tasks), to examine how the brain in people with functional movement disorders (FMD) may differ…
- Trial name
- NCT00448084
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Muscle Oxygenation
Evaluation of Muscle Oxygen With MRI
Demonstration of soft tissue hypoxia on MRI using external compression and muscle contraction.
- Trial name
- NCT07638384
- Testing
- Compression and Contraction
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Healthy Volunteers
Physiology of Volition Studied With Nerve Block
Background: The experience of volition that accompanies voluntary movement can be divided into the sense of will, or deciding to move, and the sense of agency, or feeling that the movement just made was self-generated.
- Trial name
- NCT01143506
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cannabis Dependence
Social and Emotional Brain Function in Cannabis Users
The aim of this functional magnetic resonance imaging (fMRI) study is to find out whether and how social and emotional brain function are altered in dependent cannabis users relative to healthy non-using control subjects after a…
- Trial name
- NCT02711371
- Testing
- fMRI
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Mild Cognitive Impairment
Using fMRI-guided TMS to Increase Central Executive Function in Older Adults (MCI_Sub)
This is an administrative supplement to an existing project "Using fMRI-guided TMS to increase central executive function in older adults: NCT02767323" This award allows extending our existing fMRI-TMS paradigm to patients with a…
- Trial name
- MCI_Sub (NCT04176406)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Duke University
Parkinson Disease
Individualized Precise Localization of rTMS on Primary Motor Area
Parkinson's disease (PD) patients have some problem with self-initiated movement task. Compared with health controls, task meta-analysis found that PD patients showed abnormal activation in pre-supplementary motor area (pre-SMA)…
- Trial name
- NCT03497884
- Testing
- rTMS
- Where
- 2 sites in China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hangzhou Normal University
Tourette Syndrome
The Pathophysiology of Tourette Syndrome: a Multimodal Study
The purpose of this study is to characterize the functional and anatomical connectivity changes in Tourette syndrome and its relation with iron deficiency.
- Trial name
- PTS (NCT02497807)
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Healthy
Chatbot Intervention Effects on Belief Updating in Anhedonia
The main aim of the present study is to investigate the effects of a Motivational Interviewing-based artificial intelligence chatbot on belief updating in college students with elevated levels of depression and anhedonia by…
- Trial name
- NCT07663019
- Testing
- MI Chatbot Interaction, Active Control Chatbot Interaction
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Obesity
Brain Activation in Response to Appetitive Cues Pre- and Post- Bariatric Surgery
Utilizing fMRI, this study will examine changes in BOLD signal as a proxy measure of brain activation in response to highly palatable (high energy density [kcal/g]), less palatable and non-food stimuli in severely obese women…
- Trial name
- NCT01590914
- Testing
- Fed Condition, Fasted Condition
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- New York Obesity and Nutrition Research Center
Alcohol Use Disorder
Neural and Mobile Assessment OF Behavior Change Among Problem Drinkers
This study will examine the neural mechanisms underlying both spontaneous behavior change and behavior change in response to a brief intervention among problem drinkers.
- Trial name
- NCT03457077
- Testing
- Brief intervention
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Anorexia Nervosa, Bulimia Nervosa
Study on the Mechanism of Eating Disorder
Eating disorders (EDs) are severe chronic psychiatric disorders with a not fully understood etiopathogenesis. Previous studies have revealed some biological mechanisms of EDs.
- Trial name
- NCT05862389
- Where
- China
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Peking University
Changes in Brain Network Connectivity
Anesthesia and Functional Connectivity: An Analysis of fMRI Changes
Functional connectivity is defined as a correlation in neural activity between distinct regions of the brain. Several recent studies have demonstrated areas of low-frequency functional connectivity inherent to brain tissue at…
- Trial name
- NCT02196259
- Testing
- Anesthetics, Dissociative
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Schizophrenia, Schizoaffective Disorder
Quantifying Abnormalities in Cortical Activation Associated With Auditory Hallucinations Using Functional Magnetic Resonance Imaging
The goal of the project is to characterize abnormalities in brain structure and function related to schizophrenia. The investigators will use advanced magnetic resonance imaging (MRI) techniques to measure the degree and…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Hallucinations
- Trial name
- NCT00288340
- Testing
- functional magnetic resonance imaging
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Stroke
A Longitudinal Study of Multimodal Resonance Imaging in Stroke Patients
Imaging of the ischaemic penumbra with a particular diffusion-weighted imaging (DWI)/ perfusion-weighted imaging (PWI) mismatch is a promising approach to the selection of patients with acute ischaemic stroke for trials of…
- Trial name
- NCT02024503
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Zhongda Hospital
Obesity, Brain Function
Food Intake-Related Brain and Metabolic Responses in Obesity
This study is a prospective, single-center, randomized, controlled, crossover intervention trial. A total of 60 participants, including 30 patients with obesity and 30 healthy controls, will be enrolled.
- Conditions
- Obesity, Brain Function, Metabolomics, Feeding Behavior
- Trial name
- NCT07392905
- Testing
- Glucose Liquid Meal, Fat Liquid Meal, Protein Liquid Meal
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
ASD, Functional Magnetic Resonance Imaging
MRI-Eye Tracking Pairing, a Tool for Assessing Social Cognition in Children With ASD
Most studies use static visual percepts that are less representative of joint attention versus an ecological environment. This has the consequence of decreasing the perception of an interaction with a social partner, which is an…
- Conditions
- ASD, Functional Magnetic Resonance Imaging, Eye Tracking, Social Cognition
- Trial name
- IRM-ET (NCT05194254)
- Testing
- MRI-ET
- Where
- France
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Healthy
Chatbot Intervention Effects on Social and Monetary Incentive Processing in Anhedonia
The main aim of the present study is to investigate the effects of a Motivational Interviewing-based artificial intelligence chatbot on social incentive processing in college students with elevated levels of depression and…
- Trial name
- NCT07665242
- Testing
- MI Chatbot Interaction, Active Control Chatbot Interaction
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Schizophrenia
Atypical Antipsychotic Treatment Effect On Brain Function In Schizophrenia Measured By FMRI
The general aim is to compare the effects of typical and atypical antipsychotic medication on brain structure and function. A parallel group treatment trial will be utilized to compare the effects of the typical antipsychotic…
- Trial name
- NCT01234454
- Testing
- Risperidone, Olanzapine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
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