Clinical trials: hsCRP
hsCRP
RIR and the Impact on Clinical Outcomes in Patients Undergoing PCI
Coronary heart disease (CAD) is caused by myocardial ischemia, hypoxia or necrosis due to coronary artery stenosis, spasm or obstruction.
- Trial name
- NCT05131750
- Where
- China
- Volunteers
- 1,408 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Obesity, Elevated High-sensitivity C-reactive Protein (hsCRP)
A Study to See How Safe a New Medicine (NNC6022-0004) is in Healthy People and People Living With Obesity
This study is being done to look at the efficacy single and multiple ascending dose study investigating safety, tolerability, pharmacokinetics, food effect and target engagement in healthy adults including a single cohort in…
- Trial name
- NCT07693868
- Testing
- NNC6022-0004
- Where
- Netherlands
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Chronic Kidney Diseases, Chronic Kidney Insufficiency
A Study to Evaluate TOUR006 in Patients With Chronic Kidney Disease and Elevated Hs-CRP
This study will evaluate the safety, tolerability, pharmacokinetics, and CRP-lowering effect of quarterly and monthly subcutaneous administration of TOUR006 (also known as pacibekitug) in participants with chronic kidney disease…
- Conditions
- Chronic Kidney Diseases, Chronic Kidney Insufficiency, Chronic Renal Diseases, Chronic Renal Insufficiency
- Trial name
- TRANQUILITY (NCT06362759)
- Testing
- TOUR006 - 50 MG, TOUR006 - 25 MG, TOUR006 - 15 MG
- Where
- 38 sites in United States
- Volunteers
- 143 people
- Sponsor
- Tourmaline Bio, Inc., a Novartis Company
Systemic Inflammation (hsCRP), Healthy Aging
Evaluation of AppleX™ Apple Extract on Anti-Inflammatory and Healthy Aging Effects
The goal of this clinical trial is to learn if AppleX™ Apple Extract can help lower systemic inflammation in adults aged 45-70 with signs of low-grade inflammation.
- Conditions
- Systemic Inflammation (hsCRP), Healthy Aging, Vitality, Healthy Adult Participants
- Trial name
- NCT07678346
- Testing
- Apple Extract
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nutraland USA, Inc.
Systemic Inflammation (hsCRP)
Levels of Inflammation in Middle East People With Cardiovascular Disease With/Without Kidney Disease
This study will collect medical and background information from participants with diseases that affect the heart and blood vessels (cardiovascular disease) with/without kidney disease.
- Trial name
- INFLAMEAST (NCT06655493)
- Testing
- No treatment given
- Where
- 20 sites in Saudi Arabia, United Arab Emirates
- Volunteers
- 756 people
- Sponsor
- Novo Nordisk A/S
hsCRP
Association Between Grade(B/C)of Stage III and IV Periodontitis and High Sensitivity C Reactive Protein Level in Serum and Oral Rinse Sample
According to 2017 World Workshop of Periodontology , the level of high sensitivity C reactive protein has been assumed to increase according to the grade of periodontitis, however, specific evidence regarding this is lacking at…
- Trial name
- NCT06997770
- Where
- India
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
NLRP3, hsCRP
Effect of Inflammasome Inhibitor on hsCRP in Patients After PCI
Coronary artery disease (CAD) comprises the major contributor to a global epidemic of cardiovascular disease. Patients with CAD undergoing percutaneous coronary intervention (PCI) have a high-risk for adverse clinical outcomes.
- Conditions
- NLRP3, hsCRP, Percutaneous Coronary Intervention
- Trial name
- NCT05130892
- Testing
- Colchicine, Tranilast, Oridonin
- Where
- 2 sites in China
- Volunteers
- 132 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Erectile Dysfunction, Periodontitis
Periodontal Disease as a Risk Indicator for Erectile Dysfunction - A Cross-sectional Study on 100 Patients
Background Increased levels of C reactive protein (CRP) can be found not only within individuals with periodontal diseases and those with atherosclerotic alterations but also have been proved in men with erectile dysfunction…
- Conditions
- Erectile Dysfunction, Periodontitis, hsCRP
- Trial name
- NCT01852240
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Elevated High-sensitivity C-Reactive Protein (hsCRP)
JUPITER - Crestor 20mg Versus Placebo in Prevention of Cardiovascular (CV) Events
The purpose of this study is to determine the safety and effectiveness of long-term therapy with rosuvastatin compared with a placebo, and to evaluate whether treatment with rosuvastatin might be effective in reducing the risk of…
- Trial name
- NCT00239681
- Testing
- Rosuvastatin
- Where
- 856 sites in United States, Argentina and 25 more
- Volunteers
- 17,802 people
- Sponsor
- AstraZeneca
Dyslipaemia, Atherosclerosis Risk
Dyslipaemia, Atherosclerosis Risk and Increased hsCRP and Inflammatory and Oxidative Status in the Spanish Population. Database Analysis of Previous Studies Performed in Spain
The present project is aimed at determining the prevalence of LDL-C <130 mg/dl with hsCRP ≥2mg/l, and of HDL-C < 40 mg/dl in Spain together with the estimation of cardiovascular risk, to analyze the contribution of measuring…
- Conditions
- Dyslipaemia, Atherosclerosis Risk, Increased hsCRP, Inflammatory and Oxidative Status in the Spanish Population
- Trial name
- DARIOS (NCT00998062)
- Where
- 11 sites in Spain
- Volunteers
- 30,181 people
- Sponsor
- AstraZeneca
COPD Patients, Healthy Subjects
Pulmonary Arterial Pressure Response During Exercise
Background: The extent of increase in systolic pulmonary arterial pressure (PAPs) during exercise in patients with COPD is unpredictable from lung function data.
- Conditions
- COPD Patients, Healthy Subjects, Semi-supine Echo (SSE), Flow-mediated Vasodilatation (FMD)
- Trial name
- PAPCOPDHS (NCT00949195)
- Testing
- Measure pulmonary artery pressure change during exercise, Pulmonary pressure response during exercise
- Where
- Hungary
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Szeged University
hsCRP
Investigation Into the Correlation of Plasma Hs-CRP Concentrations and Cardiovascular Risk in Korean Population
An observational, non-interventional, multi-centre study to provide further information on the utility of test for a predictive marker by investigating the current prevalence of high sensitivity CRP (hs-CRP) testing and…
- Trial name
- CALLISTO (NCT00819273)
- Where
- 10 sites in South Korea
- Volunteers
- 1,700 people
- Sponsor
- AstraZeneca