Clinical trials: i-PRF
Molar, Third, Postoperative Complications
The Use of Injectable-Platelet Rich Fibrin (i-PRF) in the Lower Third Molar Extraction
Lower third molar extraction is one of the most frequently performed surgical procedures in dentistry. Common sequelae, including pain, swelling and trismus, can severely affect patients' quality of life during the immediate…
- Trial name
- NCT06073535
- Testing
- Extraction of mandibular third molar, i-PRF
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Naples
Platelet-Rich Fibrin, Acceleration
The Effect of Multiple Injections of (PRF) on The Rate of Canine Retraction
this clinical trial aims to prove that multiple injections will produce a steady rate of acceleration of orthodontic tooth movement.
- Conditions
- Platelet-Rich Fibrin, Acceleration, Orthodontics
- Trial name
- NCT05766618
- Testing
- Injectable platelet rich fibrin (i-PRF): in acceleration of orthodontic tooth movement
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Intrabony Defect, Intrabony Defects in Chronic Periodontitis
Treatment of Intrabony Defect in Patient With Periodontitis Stage III by Using I-PRF and Xenograft
Evaluate of the injectable platelet rich fibrin (I-PRF) with xenograft in Intrabony defects of Periodontitis patient stage III versus Xenograft alone.
- Trial name
- NCT07261878
- Testing
- injectable platelet rich fibrin and xenograft, Xenograft alone
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Ridge Splitting, i-PRF
Ridge Splitting With Simultaneous Implant Placement Using i-PRF
Sohn introduced the concept of sticky bone in which i-PRF is mixed with the granules of bone graft, leading to fabrication of growth factors-enriched bone graft matrix using autologous fibrin glue.
- Conditions
- Ridge Splitting, i-PRF, Dental Implant
- Trial name
- NCT05010785
- Testing
- Immediate implant placement and alveolar ridge splitting with GBR and i-PRF, Immediate implant placement and alveolar ridge splitting with GBR
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Intrabony Periodontal Defect
Injectable Platelet Rich Fibrin With Demineralized Freeze-dried Bone Allograft in Treatment of Intraosseous Defects
Clinical and radiographic evaluation of injectable platelet rich fibrin (i-PRF) and demineralized freeze-dried bone allograft (DFDBA) compared to demineralized freeze-dried bone allograft (DFDBA) alone in management of…
- Trial name
- NCT03900013
- Testing
- Injectable platelet rich fibrin combined with DFDBA, Demineralized Freeze Dried Bone Allograft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpotomy
Assessment of I-PRF Versus Nano MTA Combined with I-PRF Scaffold in Vital Pulp Therapy in Mature Mandibular First Molars
Assessment of I-PRF versus Nano Mineral trioxide aggregate Combined with I-PRF in pulpotomy in mature Mandibular First Molars
- Trial name
- NCT06640205
- Testing
- pulpotomy
- Where
- Egypt
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Alveolar Bone Loss, Alveolar Ridge Abnormality
Repeated Injection of I PRF and Autogenous Bone Graft for Alveolar Ridge Augmentation
The current st udy's objective was to validate the repeated effect of i PRF with autogenous bone on the of gingival thickness , width a n d volumetric bone changes durig maxillary alveolar augmentation using cone beam computer…
- Trial name
- I-PRF (NCT06711250)
- Testing
- khoury technique, khoury technique with i-PRF injections
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Gingival Recession
Evaluation of Root Coverage After the Use of Coronally Advanced Flap Either With Advanced Paltelet Rich Fibrin or Subepithilial Connective Tissue Graft in Treatment of Miller Class I and II Gingival Recession.
patients with Miller class I , II gingival recession will be divided into 2 groups (control, intervention).the control one will receive coronally advanced flap with subepithililal connective tissue graft harvested from the palate…
- Trial name
- NCT03695549
- Testing
- CAF + (A-PRF), CAF+SCTG
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Esthetic Zone
Efficacy of i-PRF Usage in Vestibular Socket Therapy
This study aims for evaluation of A novel method for evaluating i-PRF usage in vestibular socket therapy for immediate implant in defective fresh extraction site.
- Trial name
- NCT07304986
- Testing
- Immediate implant with VST, Immediate implant with VST and i-prf
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Alveolar Osteitis, Pain
Investigation of the Effect of I-PRF Application on Pain in Alveolitis
Literature review showed that there are no studies on the use of i-PRF in alveolitis cases. The aim of this study was to investigate the effect of i-PRF on the treatment of alveolitis.
- Conditions
- Alveolar Osteitis, Pain, Dry Socket
- Trial name
- NCT06761001
- Testing
- I-PRF, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Periodontitis, Intrabony Periodontal Defect
Treatment of Intrabony Defects With Injectable Platelet-Rich Fibrin and Xenogenic Grafts
The use of injectable platelet-rich fibrin (i-PRF) in both surgical and non-surgical dental treatments has become increasingly widespread.
- Conditions
- Periodontitis, Intrabony Periodontal Defect, Periodontal Diseases, Periodontal Defect
- Trial name
- NCT07146776
- Testing
- open flap debridement with I-prf and xenogeneic graft, open flap debridement with saline and xenogenic graft
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Apical Lesion
The Effect of Injectable Platelet Rich Fibrin on Apical Lesion Healing
In recent years, the use of autologously obtained blood products that stimulate cell proliferation, such as platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), has become increasingly widespread.
- Trial name
- NCT07876427
- Testing
- i-PRF, root canal treatment and intracanal medicament
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hande Has Elçi
Periodontal Pocket, Periodontitis
PRF Therapy for Pocket Reduction
Periodontal regenerative therapy has focused on various non-surgical and surgical treatment methods. Platelet-rich fibrin (PRF) has shown to possess multiple uses, including properties that promote healing of both soft and hard…
- Trial name
- NCT05908929
- Testing
- SRP and concomitant insertion of PRF membrane, SRP
- Where
- 2 sites in Italy
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Federico II University
Root Resorption
Treatment of Internal Inflammatory Root Resorption Using Injectable PRF Revascularization Technque
Currently Endodontics looks forward for regeneration rather than repair. Regenerative endodontic therapy was limited to pulp revascularization of necrotic pulp in immature teeth , followed by mature teeth.
- Trial name
- NCT04410679
- Testing
- injectable PRF
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Pulpitis - Irreversible, Apical Periodontitis
Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp Treatments
With consideration of the previous studies regarding the properties of i-PRF, it will be used in combination with another bioactive material: (Nano-BAG) versus using of i-PRF only as a pulpotomy material with using a premixed…
- Trial name
- NCT05902936
- Testing
- Pulpotomy for mature permanent mandibular molars
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Socket Preservation
Evaluation of Dentin Graft and I-PRF With and Without Vitamin C for Post-extraction Socket Preservation
The aim of the study is to evaluate radiographic ridge width change following autogenous demineralized dentin graft (ADDG) and i-PRF addition with and without vitamin C (AA) for post extraction socket preservation.
- Trial name
- NCT06569264
- Testing
- Alveolar ridge preservation using autogenous demineralized dentin graft and i-PRF, Alveolar ridge preservation using vitamin C with dentin graft and i-PRF
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Intrabony Periodontal Defects
Minimally Invasive Non Surgical Treatment Using Injectable Platelet Concentrate in Treatment of Deep Pockets.
The purpose of this study is to evaluate change in pocket depth following using minimally invasive non surgical combined with injectable platelet concentrate .
- Trial name
- NCT07722390
- Testing
- Injectable PRF, MINST
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis
Effect of Injectable Platelet-Rich Fibrin (i-PRF) in Initial Treatment of Chronic Periodontitis
Current treatments of periodontitis have limited efficacy since they fail to suppress microorganisms satisfactorily over time. The aim of present study was to investigate whether there are differences between initial treatment of…
- Trial name
- EIPRFITCP (NCT04178590)
- Testing
- SRP + Injectable Platelet-Rich Fibrin
- Where
- Serbia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Periodontal Healing, Periodontitis
The Effectiveness of Root Planing and Injectable Platelet-Rich Fibrin in Smoking Patients With Periodontitis
Periodontitis is a chronic, multifactorial inflammatory disease characterized by the progressive destruction of the tissues supporting the teeth, associated with dysbiotic plaque biofilms.
- Conditions
- Periodontal Healing, Periodontitis, i-PRF
- Trial name
- NCT07049549
- Testing
- Injectable PRF, Plasebo (Sterile Saline)
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Gingival Recession
Biofunctionalization of a Volume-stable Collagen Matrix (VCMX) for the Treatment of Single Gingival Recession
The treatment of single gingival recessions comprises different well-established techniques, and the association between coronally advanced flap (CAF) and the subepithelial connective tissue graft is considered the gold standard.
- Trial name
- NCT05916742
- Testing
- CAF, i-PRF, VCMX
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho