Clinical trials: in Vitro Fertilisation
Poor Ovarian Response
Effect of Recombinant Human Growth Hormone Injection on the Clinical Outcome of POR in Patients Undergoing IVF/ET
Observe the clinical efficacy and safety of Recombinant Human Growth Hormone Injection assisted in the treatment of the patients with poor ovarian response in vitro fertilization and embryo transfer.
- Trial name
- NCT02801591
- Testing
- Conventional ovarian stimulation proctol without rhGH
- Where
- 2 sites in China
- Volunteers
- 240 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Fertility Disorders
Evaluating the Usability of the Product Kinder System Trial, Home Based Hormone for In-Vitro Fertilization (IVF) Monitoring System.
In-vitro fertilisation (IVF) treatment involves women undergoing hormone stimulation (drug dosing) to produce more oocytes (eggs) to increase their chances of fertilisation.
- Trial name
- NCT05634850
- Testing
- Kinder
- Where
- Singapore
- Volunteers
- 25 people
- Sponsor
- Planet Innovation
Infertility
US Eeva™ Pregnancy Investigational Clinical Study (US EPIC)
The purpose of this clinical investigation is to gather data to evaluate the impact of using Eeva with traditional morphology grading on implantation rates.
- Trial name
- US EPIC (NCT01671657)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Progyny, Inc.
Controlled Ovarian Stimulation
A Study to Assess the Efficacy and Safety of Ganirelix (Orgalutran®) Treatment in Chinese Women Undergoing Controlled Ovarian Stimulation for in Vitro Fertilization (IVF) or Intra Cytoplasmatic Sperm Injection (ICSI) (Study 38651)(P05703)
The primary purpose of this study is to assess that ganirelix is safe and well-tolerated in Chinese women and that a controlled ovarian stimulation (COS) protocol combining recombinant follicle stimulating hormone (recFSH) with…
- Trial name
- NCT00725491
- Testing
- ganirelix, triptorelin
- Volunteers
- 259 people
- Sponsor
- Organon and Co
Infertility
A Phase IV, Prospective, Observational, Open Label, Single Centre Cohort Trial to be Conducted in Norway During One Year to Assess the Cumulative Pregnancy Rate in a New Series of In-vitro Fertilization (IVF) Treatment Cycles Following Three or More Previous IVF Treatment Cycles Without Live Birth
The primary objective of this observational study is to assess the cumulative rate of ongoing pregnancy at 10 ±2 weeks after hCG administration in a new series of IVF-treatment cycles in a total of 176 subjects, who have…
- Trial name
- NCT01071148
- Where
- Norway
- Volunteers
- 166 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Fertilization in Vitro
Post-Marketing Surveillance of the Safety and Efficacy of Orgalutran (Ganirelix)®
The purpose of this post-marketing surveillance is to identify problems and questions regarding the safety and efficacy of Orgalutran (Ganirelix)® when used for the prevention of premature luteinizing hormone (LH) surges in women…
- Trial name
- NCT01304511
- Testing
- Orgalutran
- Volunteers
- 711 people
- Sponsor
- Organon and Co
Female Infertility
Phase IV Study to Evaluate the Efficacy and Safety of Fang Le Shu Compared to Guo Na Fen for Controlled Ovarian Stimulation in Infertile Women Undergoing in Vitro Fertilization-embryo Transfer (IVF-ET).
The aim of this randomized, open-label, active-controlled, parallel-group, multicenter, phase IV study is to assess the efficacy and safety of Fang Le Shu versus Guo Na Fen used for controlled ovarian stimulation in infertile…
- Trial name
- NCT06921395
- Testing
- Fang Le Shu (Follitrope), Guo Na Fen (Gonal-F)
- Where
- China
- Volunteers
- 248 people
- Sponsor
- LG Chem
Infertility
A Dose-response Trial Using FE 999049 in Japanese Women Undergoing in Vitro Fertilisation (IVF) / Intracytoplasmic Sperm Injection (ICSI) Treatment
This trial investigates the effects of several doses of FE 999049 in Japanese women undergoing IVF/ICSI treatment.
- Trial name
- NCT02309671
- Testing
- FE 999049, follitropin beta
- Where
- Japan
- Volunteers
- 159 people
- Sponsor
- Ferring Pharmaceuticals
In Vitro Fertilization
Follow-up Protocol on the Outcome of Frozen-thawed Embryo Transfer Cycles From Clinical Trial P05690 (P05711)
Clinical trial objective is to collect the outcome of Frozen-Thawed Embryo Transfer (FTET) cycles performed after the embryos are cryopreserved in the base study P05690 in order to estimate the cumulative pregnancy rate for each…
- Trial name
- NCT00702546
- Testing
- corifollitropin alfa, recFSH (follitropin alfa), gonadatropin releasing hormone (GnRH) antagonist ganirelix
- Volunteers
- 102 people
- Sponsor
- Organon and Co
Infertility
Experience of Pain During Oocyte Retrieval- a Comparison Between Two Aspiration Needles
The purpose of the study is to compare the pain experience between the patients that have had their transvaginal oocytes retrieval with ultrasound guidance performed with reduced single lumen needle (Vitrolife Sweden AB…
- Trial name
- NCT00924885
- Testing
- Swemed Follicle Aspiration Set Reduced Single Lumen, Swemed Follicle Aspiration Set Single Lumen (1.4 mm)
- Where
- 4 sites in Sweden
- Volunteers
- 257 people
- Sponsor
- Vitrolife
Fertility Disorders
Menopur And Rekovelle Combination Study
This study proposes to evaluate the effect of adding HP-hMG (Menopur) to follitropin delta in a "mixed protocol" regimen, using an individualized, fixed dose of follitropin delta based on the established algorithm, combined with…
- Trial name
- MARCS (NCT03483545)
- Testing
- Follitropin delta and HP-hMG
- Where
- 4 sites in Canada
- Volunteers
- 160 people
- Sponsor
- Dr François Bissonnette
Ovulation Induction, Infertility
An Open Label, Canadian Phase IIIb Study With Ovidrel in Ovulation Induction (OI) and Assisted Reproductive Technique (ART)
With the development of the recombinant gonadotrophins, the use of human source proteins for the production of hormones has become unnecessary.
- Trial name
- NCT01152866
- Testing
- Choriogonadotropin alpha (r-hCG)
- Volunteers
- 3 people
- Sponsor
- EMD Serono
Infertility (IVF Patients)
Study of Abnormally Fertilized Embryos
The goal of this observational study is to determine the diploidy rate of haploid and triploid embryos from in vitro fertilization (IVF) cycles.
- Trial name
- SAFE (NCT06940973)
- Testing
- Parental samples, PGT-A, TE rebiopsies and spent blastocyst media collection
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Igenomix
Luteal Hormone Supplementation
A Phase III Study of FE 999913 in Japanese Female Patients Undergoing Fertility Treatment
The purposes of the study are to verify sufficient supplementation of luteal hormone after administrating FE999913 Vaginal Tablet twice a day (BID) or three times a day (TID) and to determine the efficacy and safety of FE999913…
- Trial name
- NCT01710514
- Testing
- FE 999913 vaginal tablet
- Where
- 6 sites in Japan
- Volunteers
- 108 people
- Sponsor
- Ferring Pharmaceuticals
Infertility
Adjuvant Growth Therapy in in Vitro Fertilization
In an In Vitro Fertilization (IVF) cycle super ovulating drugs (gonadotropins) are usually taken to stimulate the ovaries to produce more than one egg.
- Trial name
- NCT01715324
- Testing
- Adjuvant Growth Hormon
- Where
- Canada
- Volunteers
- 288 people
- Sponsor
- Clinique Ovo
In Vitro Maturation of Oocytes
Fertilo In Vitro Research Study and Trial
The goal of this clinical trial is to evaluate the safety and efficacy of using Fertilo for In vitro maturation (IVM) in participants 18-35 years of age.
- Trial name
- FIRST (NCT06858111)
- Testing
- Fertilo, Medicult IVM
- Where
- 16 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Gameto, Inc.
Infertility
AMH and Pregnancy Rate by Age During Stimulate In-Vitro Fertilization Protocol
The woman fertility decrease with the age and there is a closely link with the ovarian reserve, the number of available eggs in the ovaries.
- Trial name
- NCT01762111
- Where
- Canada
- Sponsor
- Clinique Ovo
Pregnancy, Neonates
Pregnancy and Neonatal Follow-up of Ongoing Pregnancies Established in Clinical Trial P05787 (P05712)
The objective of this trial was to evaluate whether Corifollitropin Alfa treatment for the induction of multifollicular growth in women undergoing controlled ovarian stimulation (COS) prior to in vitro fertilization (IVF) or…
- Trial name
- NCT00703014
- Testing
- Corifollitropin Alfa 150 μg, 200 IU RecFSH/Follitropin beta (Days 1 to 7), 200 IU RecFSH/Follitropin beta (Days 8 to hCG)
- Volunteers
- 541 people
- Sponsor
- Organon and Co
Infertility
Eeva™ Pregnancy Investigational Clinical Study: A Postmarket Follow-Up Study
The purpose of this postmarket study is to gather data to evaluate the impact of using Eeva with traditional morphology grading on clinical pregnancy rates.
- Trial name
- EPIC (NCT01671644)
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 104 people
- Sponsor
- Progyny, Inc.
Women With Fertility Disorder
Effect of Glucagon on Uterine Contractility at the Time of Embryo Transfer in in Vitro Fertilization
The success of in vitro fertilization is based mainly on uterine implantation embryo. An excessive uterine contractility may interfere with implantation by a movement of the embryo in the uterus.
- Trial name
- NCT01674283
- Testing
- Glucagon
- Where
- Canada
- Sponsor
- Clinique Ovo