Clinical trials: mTBI - Mild Traumatic Brain Injury
Concussion, MTBI - Mild Traumatic Brain Injury
Online Treatment Recovery Assistance for Concussion in Kids
The investigators propose to develop a software platform, OnTRACK (Online Treatment Recovery Assistance for Concussion in Kids), for children and adolescents recovering from concussion or mild traumatic brain injury (mTBI).
- Trial name
- OnTRACK (NCT05065099)
- Testing
- Online Treatment Recovery Assistance for Concussion in Kids (OnTRACK)
- Where
- United States
- Volunteers
- 408 people
- Sponsor
- Children's National Research Institute
Traumatic Brain Injury, Dementia
Amyloid Accumulation After Mild Traumatic Brain Injury
We are extending the researches of Taiwan neurosurgery traumatic brain injury (TBI) database which is led by Professor WT Chiu in Taipei Medical University and will recruit mild TBI (mTBI) participants who have ever been…
- Conditions
- Traumatic Brain Injury, Dementia, Alzheimer Disease
- Trial name
- TBI (NCT02134041)
- Testing
- traumatic brain injury
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Brain Concussion, Mild Traumatic Brain Injury
Get Going After concussIonN Lite
Background: Concussion affects around 25 000 people each year in Denmark. A large research initiative (GAIN 2.0) has been established, and the current study is a part of this initiative. Aims: 1.
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Commotio Cerebri
- Trial name
- GAIN Lite (NCT05233475)
- Testing
- Enhanced usual care (EUC), Get Going after concussIoN Lite
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Vestibular Rehabilitation
Vestibular Rehabilitation Exercise in Mild Traumatic Brain Injury
Traumatic brain injury (TBI) is a leading cause of long-term disability and mortality. The costs associated with hospitalization, rehabilitation, and productivity losses after injury impose a significant socioeconomic and…
- Trial name
- NCT06118541
- Testing
- Vestibular Rehabilitation therapy
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Adult Growth Hormone Deficiency, Mild Traumatic Brain Injury
Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)
The purpose of this study is to determine whether growth hormone replacement therapy (GHRT) is effective versus placebo in the improvement of Quality of Life in patients with adult growth hormone deficiency (AGHD) and mild…
- Trial name
- GRIT (NCT04867317)
- Testing
- Somatropin
- Where
- 16 sites in United States
- Volunteers
- 172 people
- Sponsor
- VA Office of Research and Development
Mild Traumatic Brain Injury, Gait
Objective Dual-task Turning Measures for Return-to-duty Assessments
The overall objective is to evaluate objective dual-task turning measures for use as rehabilitative outcomes and as tools for return-to-duty assessments in individuals with mild traumatic brain injury (mTBI).This project consists…
- Conditions
- Mild Traumatic Brain Injury, Gait, Balance, Veterans
- Trial name
- reTURN (NCT03892291)
- Where
- 6 sites in United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Brain Concussion, Mild Traumatic Brain Injury
Rehabilitation, Education, and SElf-management for Adolescents After Mild Traumatic Brain Injury
Concussion or mild traumatic brain injury (mTBI) is a major public health concern. Most adolescents will recover from mTBI without complication; however, a sizeable minority experience symptoms that last more than one most…
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Concussion
- Trial name
- RESET (NCT07698015)
- Testing
- Mindfulness-based intervention, Health Education
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Molly Cairncross
Trauma, Head, Headaches Posttraumatic
Frequency Specific Microcurrent Therapy for Mild Traumatic Brain Injury
Patients with mild traumatic brain injury (mTBI) may experience spontaneous recovery within 7-10 days, but some continue to exhibit symptoms such as headache, dizziness, vertigo, poor concentration, and cognitive dysfunction.
- Conditions
- Trauma, Head, Headaches Posttraumatic, Dizziness, Brain Concussion
- Trial name
- NCT06245967
- Testing
- Frequency specific microcurrent therapy
- Volunteers
- 52 people
- Sponsor
- China Medical University Hospital
Traumatic Brain Injury, Trauma
The Effect of Mild Traumatic Brain Injury on Recovery From Injury
Mild traumatic brain injury (TBI) is a common injury that can produce significant functional sequelae and ongoing disabling symptoms.
- Conditions
- Traumatic Brain Injury, Trauma, Head Injury, Brain Concussion
- Trial name
- NCT00295074
- Testing
- neuropsychologic testing
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Pittsburgh
Persistent Post-concussive Syndrome, Concussion Post Syndrome
Hyperbaric Oxygen Effects on Persistent Post-concussive Symptoms
Persistent post-concussive symptoms (PPCS) are a source of significant burden among a subset of patients with concussion with prevalence rates previously reported between 11 - 82% based on timing of assessment, diagnostic…
- Trial name
- HOINPCS (NCT05173818)
- Testing
- Hyperbaric oxygen at 1.5 ATA
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Essentia Health
Mild Traumatic Brain Injury, Concussion, Mild
Facilitating Access to Specialty Treatment
The goal of this hybrid implementation-effectiveness study is to evaluate the effectiveness (hastened recovery times) and feasibility (fidelity in connecting to concussion specialty care) of a novel mobile health intervention…
- Conditions
- Mild Traumatic Brain Injury, Concussion, Mild, Concussion, Severe, Concussion, Intermediate
- Trial name
- NCT05741411
- Testing
- RPM-assisted specialist access
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Children's Hospital of Philadelphia
MTBI - Mild Traumatic Brain Injury, Concussion, Mild
Evaluation of Helmet Technology and Head Impact Exposure
The purpose of the study is to monitor longitudinal changes in brain structure and function between the preseason and postseason, in a population of football playing athletes grouped by helmet make and model.
- Trial name
- NCT03883451
- Testing
- Helmet Model
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Mild Traumatic Brain Injury, Cognitive Impairment
Brief Telehealth Cognitive Rehabilitation Following Mild TBI
In the United States, more than a million people sustain a mild traumatic brain injury (mTBI) every year. Although many recover fully, emerging literature suggests a high number of individuals report chronic, and functionally…
- Trial name
- On-TRACC (NCT05315453)
- Testing
- Brief Cognitive Rehabilitation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Washington
Post-Concussion Syndrome
Rehabilitation in Post Concussion Syndrome
This project evaluates and quantifies the effects of an individually tailored exercise program applied to patients with long-lasting symptoms after concussion, minor traumatic brain injury, so-called Post-Concussion Syndrome…
- Trial name
- REPCon (NCT05785000)
- Testing
- Physical exercise programme as an add-on, Control patients receiving usual care
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Orthopaedic Injuries, Concussion (Diagnosis)
The TCU Division I Collegiate Athlete Study
The overall objective of this study is to identify risk factors for two of the most common types of injuries in collegiate athletics - orthopedic injuries and concussion injuries.
- Trial name
- NCT07006051
- Testing
- Exposed group
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Traumatic Brain Injury
Effects of LEDs on Memory in TBI Patients
The purpose of the study is to investigate whether transcranial, high-intensity LED placed on the scalp can improve working memory in people who have sustained a concussion with lingering effects or a mild brain injury.
- Trial name
- LED (NCT01598532)
- Testing
- MedX Health Phototherapy (light therapy)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Spaulding Rehabilitation Hospital
Brain Concussion
Telephone Follow-Up on Outcome After Mild Traumatic Brain Injury
The purpose of this study is to see whether providing education and counseling after a mild traumatic brain injury will help in preventing symptoms from becoming chronic over the first six months after injury.
- Trial name
- TBI (NCT00483444)
- Testing
- Scheduled telephone follow-up
- Where
- United States
- Volunteers
- 366 people
- Sponsor
- University of Washington
Brain Injuries, Traumatic, Concussion, Mild
Validation of Brain Function Assessment Algorithm for mTBI/Concussion
This study is Part 2 of data collection from 13-25 years old subject population for validation of previously derived algorithms.
- Conditions
- Brain Injuries, Traumatic, Concussion, Mild, Concussion, Severe, Concussion, Intermediate
- Trial name
- CAS13-25V (NCT03671083)
- Testing
- BrainScope Ahead 300iP
- Where
- 5 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- BrainScope Company, Inc.
Traumatic Brain Injury
Assessing Eye Tracking Features Following Sports-Related Concussion
This proposal aims to describe the oculometric features present during King-Devick (K-D) testing for subjects who experienced sports-related concussion.
- Trial name
- NCT02103803
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Mayo Clinic
Brain Concussion
Microstructural Changes in the Brain During Recovery After Mild Traumatic Brain Injury
This study examines the possible microstructural changes in the brain during recovery after mTBI using diffusion MRI.
- Trial name
- NCT02350894
- Testing
- Graded and behavevial theraphy
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- University of Aarhus