Clinical trials: miRNAs
miRNAs, Carotid Plaque
Study of microRNAs in the Evolution of Carotid Plaque. Physiopathological and Therapeutic Interest
Carotid stenosis of atherosclerotic origin may be responsible for stroke, which is one of the most important causes of morbidity and mortality in the Western world
- Trial name
- NCT03149406
- Testing
- Comparing the expression of miRNAs
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Exercise Training, Microgreens
Microgreens and miRNAs
In this study, we investigated the impact of a comprehensive microgreen and wheatgrass juice protocol on the miRNA response following a standardized EIMD model and whether microgreen consumption could modulate key miRNA markers…
- Conditions
- Exercise Training, Microgreens, miRNAs
- Trial name
- GreenmiRNAs (NCT07540858)
- Testing
- Microgreens, not received any supplement
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Breast Cancer, Metastatic Breast Cancer
PTEN and Organ-Specific microRNAs in Metastatic Breast Cancer
This prospective observational study aims to evaluate serum levels of PTEN, a tumor suppressor gene, and organ-specific microRNAs (miRNAs) associated with metastatic patterns in breast cancer.
- Conditions
- Breast Cancer, Metastatic Breast Cancer, miRNAs, PTEN
- Trial name
- PTEN-miR-MBC (NCT07297134)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Atlas University
Degeneration Disc Intervertebral, miRNA
Investigation of miRNA Expression Profiles in Human Degenerated Intervertebral Disc Tissues
Aim of the Study: The aim of this study is to determine the expression levels of candidate microRNAs (miRNAs) expressed in human degenerated intervertebral disc tissues.
- Trial name
- MIRADISC (NCT07114497)
- Testing
- surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines, excised, Diagnostic work up
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
miRNA
Circulating microRNAs and Adverse Cardiovascular Outcomes in Patients With Coronary Artery Disease
Coronary artery disease (CAD) resulting from atherosclerotic obstruction of epicardial coronary arteries accounts for more than one-third of deaths in subjects over the age of 35 worldwide.
- Trial name
- NCT03635255
- Where
- Taiwan
- Volunteers
- 460 people
- Sponsor
- National Taiwan University Hospital
Glioma, miRNA
Monitoring of Patients With Low-grade Gliomas Using Circulating miRNA
With around 3,400 cases per year in France, diffuse gliomas are the most common primary tumours of the central nervous system. Their grade varies from 2 to 4.
- Conditions
- Glioma, miRNA, Low-grade Glioma, Biomarkers
- Trial name
- GLIBAMIR (NCT06610851)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Caen
Periodontal Therapy, miRNA-223
The Effects of Smoking on miRNA-223 Before-After Non-Surgical Periodontal Therapy
Periodontal diseases are one of the most common inflammatory diseases. Periodontal disease results from a complex interplay between the subgingival biofilm and the host immune-inflammatory events that develop in the gingival and…
- Conditions
- Periodontal Therapy, miRNA-223, Periodontitis, Biomarker
- Trial name
- NCT05372965
- Testing
- experimental-periodontitis-mirna-223-gingival tissue-saliva samples, control-clinical healthy mirna-223-gingival tissue-saliva samples
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Biruni University
Multiple Sclerosis, miRNA
miRNA Biomarkers in Multiple Sclerosis
Multiple Sclerosis (MS) characterized by demyelination and axonal degeneration is a chronic inflammatory disease of the central nervous system (CNS).
- Conditions
- Multiple Sclerosis, miRNA, Epigenetic, Biomarker
- Trial name
- NCT04772495
- Testing
- miRNA
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Chronic Periodontitis, Coronary Artery Disease
Interplay of miRNA-146a and miRNA-126 in Chronic Periodontitis Patients With Coronary Artery Disease
The role of micro-RNAs in chronic periodontitis associated with CAD is still in an incipient stage needs to be explored further.
- Conditions
- Chronic Periodontitis, Coronary Artery Disease, miRNA
- Trial name
- NCT04583085
- Where
- India
- Volunteers
- 75 people
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Dexamethasone Effect on miRNA Profile in Healthy Humans
Detection of miRNAs in HPA Axis Function in Healthy Subjects
The proposed study will test dexamethasone effect on miRNA profile in healthy humans. As our data indicate that miRNA levels change over time, the investigators will study the time course of miRNA response to 1 mg IV…
- Trial name
- NCT04066647
- Testing
- Dexamethasone 4mg
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
PRU, miRNA
The Relationship of Platelet Micro-RNA Expression and Platelet Reactivity in Patients Under Clopidogrel or Ticagrelor Treatment
For acute coronary syndrome patients undergoing cardiac catheterization after stenting, we will give dual antiplatelet drugs (dual antiplatelet agents) therapy, the choice of the basis of medical criteria (clinical guidelines)…
- Trial name
- NCT02101437
- Testing
- miRNA within 24hr, miRNA after 1 week, miRNA after 1 month
- Where
- Taiwan
- Volunteers
- 175 people
- Sponsor
- Taipei City Hospital
miRna in HCC
Study of microRNAs as a Diagnostic Tool for HCV-related Hepatocellular Carcinoma
The aim of this work is to study the role of circulating miRNAs in diagnosis of HCV related hepatocellular carcinoma.
- Trial name
- NCT03429530
- Volunteers
- 100 people
- Sponsor
- HMHamed