Clinical trials: multiple sclerosis
Traumatic Brain Injury, Stroke
Remote Neuropsychological Assessment of Patients With Neurological Disorders and Injuries
For the last decades, many aspects of human life have been altered by digital technology. For health care, this have opened a possibility for patients who have difficulties travelling a long distance to a hospital to meet with…
- Conditions
- Traumatic Brain Injury, Stroke, Multiple Sclerosis, Parkinson Disease
- Trial name
- NCT05819008
- Testing
- Neuropsychological Assessment
- Where
- Sweden
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Umeå University
Multiple Sclerosis
Disability Level and Trunk Control in Individuals With Multiple Sclerosis
Trunk control disorders are frequently encountered in individuals with MS. Trunk control is very important for safe and quality movement.
- Trial name
- NCT05634993
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Multiple Sclerosis
Intermediate Expanded Access Protocol CNMAu8.EAP03
This is a single-center intermediate expanded access program to provide access to the investigational product, CNM-Au8, up to 25 participants diagnosed with Multiple Sclerosis.
- Trial name
- NCT04081714
- Testing
- CNM-Au8
- Where
- United States
- Sponsor
- Clene Nanomedicine
Multiple Sclerosis
The Reliability and Validity of the L-test in Patients With Multiple Sclerosis
Walking safely inside or outside is an important function in patients with Multiple Sclerosis (PwMS) that affects their daily life activity and participation.
- Trial name
- NCT05641714
- Testing
- L test, Timed Up and Go test, 10 meter walk test
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Gazi University
Multiple Sclerosis, Pain
Effects of Telerehabilitation-Based Motor Imagery Training on Pain in People With Multiple Sclerosis
In this studly, the effects of an 8-week telerehabilitation-based motor imagery training on pain and related factors in persons with multiple sclerosis will be investigated.
- Trial name
- NCT05326711
- Testing
- Telerehabilitation-based motor imagery training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Dokuz Eylul University
Multiple Sclerosis
Open Label Study to Evaluate Effect, Safety and Tolerability of Betaferon Standard Dose of 250µg in Patients of Chinese Origin With Multiple Sclerosis
The purpose of this study is to determine if the study drug is effective and safe in the treatment of Multiple Sclerosis (MS) in patients of Chinese origin.
- Trial name
- NCT00370071
- Testing
- Interferon beta-1b (Betaseron, BAY86-5046)
- Where
- 3 sites in China
- Volunteers
- 39 people
- Sponsor
- Bayer
Multiple Sclerosis
Reducing Sedentary Behaviour: A Novel Opportunity for Managing Comorbidity in MS?
Activity recommendations for the general population and those with multiple sclerosis (MS) focus on the promotion of activity that has a moderate intensity - in other words, activity intense enough to breathe heavily and sweat.
- Trial name
- NCT03136744
- Testing
- Sit Less with MS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Multiple Sclerosis
Correlation Between the 'Nine Holes Peg Test' Performance and the Triple Stimulation Technique Within a Group a Patients With Multiple Sclerosis
The main goal of this study is to determine if the Triple Stimulation Technique (TST) can be correlated to performance in the manual dexterity 'nine holes peg' test, within a control group and a group of patients with multiple…
- Trial name
- NCT02805634
- Testing
- Nine Hole Test, Triple Stimulation Technique
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Multiple Sclerosis
A Phase 1 Study of ARN-6039
This Phase 1 study intends to determine the safety and tolerability of ARN-6039 in healthy subjects.
- Trial name
- ARN-6039 (NCT03237832)
- Testing
- ARN-6039
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Arrien Pharmaceuticals
Urinary Bladder, Neurogenic
Urodynamic and Clinical Efficacy of Mirabegron for Neurogenic Bladder Patients
The proposed study is a randomized, double blind placebo controlled multicenter study to determine the effectiveness of mirabegron in the treatment of neurogenic bladder dysfunction.
- Trial name
- NCT02044510
- Testing
- Mirabegron
- Where
- 5 sites in Canada
- Volunteers
- 32 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Autoimmune Encephalitis (AE), Acute Disseminated Encephalomyelitis
OPM- MEG in Non-immune And iMmune-medIated Neurological Disease
Over the past 20 years, doctors have gotten much better at spotting and treating brain conditions caused by the immune system attacking the body. These include illnesses like autoimmune encephalitis, ADEM, and multiple sclerosis.
- Conditions
- Autoimmune Encephalitis (AE), Acute Disseminated Encephalomyelitis, Multiple Sclerosis
- Trial name
- O-MEG-A-MIND (NCT07689682)
- Testing
- OPM- Magnetoencephalography
- Where
- 2 sites in United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aston University
Spinal Cord Injuries, Multiple Sclerosis
Validity and Reliability of Turkish Version Leg Activity Measure
Patient-filled scales minimize the burden of data collection for clinicians in a clinical setting. Therefore, Leg activity measure, a new self-report measure of active and passive function in the leg, has been developed.
- Conditions
- Spinal Cord Injuries, Multiple Sclerosis, Stroke
- Trial name
- NCT05182411
- Testing
- assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Multiple Sclerosis, Relapsing-Remitting
Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation
The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., presupplementary motor area) thought to aid in memory will improve…
- Trial name
- MS-HDtDCS (NCT05958381)
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas at Dallas
Multiple Sclerosis
Famciclovir in Multiple Sclerosis
This is a proof-of-concept study in 30 patients with established Relapsing Remitting Multiple Sclerosis (RRMS). IMP is Famciclovir. It is a phase II type A open label study.
- Trial name
- NCT05283551
- Testing
- Famciclovir
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Queen Mary University of London
Multiple Sclerosis, COVID-19
COVID-19 on Disease Activity in Radiologically Isolated Syndrome Cohort
The Radiologically Isolated Syndrome (RIS) is defined as incidental Magnetic Resonance Imaging (MRI) abnormalities fulfil the criteria for dissemination in space, suggestive of multiple sclerosis.
- Trial name
- VaxiRIS (NCT05387395)
- Testing
- NO intervention
- Where
- France
- Volunteers
- 217 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Multiple Sclerosis, Physical Disability
Measuring Consequences of Disability for Patients With Multiple Sclerosis and Caregivers on Economic Burden
The objective of this study is to measure economic burden of Multiple Sclerosis (MS) from a new point of view that includes consequences of disability on Quality Of Life (QOL), social participation and capabilities of patients…
- Conditions
- Multiple Sclerosis, Physical Disability, Economic Burden, Social Interaction
- Trial name
- ECOPASEP (NCT02592265)
- Volunteers
- 233 people
- Sponsor
- Lille Catholic University
Patients With Multiple Sclerosis
Clinical Correlates of Psychiatric Comorbidities in Patients With Multiple Sclerosis
Many neuropsychiatric abnormalities associated with multiple sclerosis (MS). These may be broadly divided into 2 categories: disorders of mood, affect,and behavior and abnormalities affecting cognition.
- Trial name
- NCT05382195
- Testing
- hospital anxiety and depression scale
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Multiple Sclerosis
Safety and Efficacy of Intrathecal Rituximab in Patients With Multiple Sclerosis
Considering the accumulated data on the pathogenesis of multiple sclerosis, indicating a significant role of B cells in the progression of the disease, the use of monoclonal antibodies to CD20 antigen, administered intrathecally…
- Trial name
- NCT05078177
- Testing
- Rituximab
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Multiple Sclerosis
LoveYourBrain Yoga for Multiple Sclerosis
The purpose of the study is to assess the feasibility of a 6-week yoga and meditation intervention for people with multiple sclerosis (MS).
- Trial name
- NCT03827928
- Testing
- Yoga/meditation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Multiple Sclerosis
Phase III Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Immune Globulin for Multiple Sclerosis
OBJECTIVES: I. Determine whether high-dose intravenous immune globulin (IVIG) is more effective than placebo in restoring neurologic function (muscle strength) in patients with multiple sclerosis. II.
- Trial name
- NCT00004744
- Testing
- immune globulin
- Volunteers
- 76 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
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