Clinical trials: no Conditions
No Applicable Condition; Study of Physiologic Monitor Alarms
Quality Improvement - Monitoring Alarm Optimization Study
This project aims to reduce the frequency of duplicate, false and clinically insignificant alarms in hospital units, and subsequent alarm fatigue resulting from excessive alarm frequency.
- Trial name
- QI-MAOS (NCT02916212)
- Testing
- Optimized alarm profiles
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Pelvic Floor Disorders, Urinary Incontinence
Effects of Epi-no Device on Pelvic Floor Dysfunctions
Perineal injury is the most common maternal obstetric complication associated with vaginal delivery. Perineal traumas are associated with maternal morbidity, including pain, urinary and fecal incontinence, genital prolapses…
- Conditions
- Pelvic Floor Disorders, Urinary Incontinence, Dyspareunia, Lacerations Perineal
- Trial name
- NCT04955418
- Testing
- Epi-No®, Evaluation
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Healthy
ClearView Predicate Comparison Testing
This study serves as a comparison study between the EPIC ClearView and a predicate device.
- Trial name
- NCT01573559
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Healthy
Bioequivalence Study of Fluoxetine HCL 40 mg Capsules Under Fasting Conditions
The objective of this study is to compare the relative bioavailability of fluoxetine HCL 40 mg capsules (by Ranbaxy Laboratories Limited) with that of PROZAC® 40 mg capsules (by Dista Products Company) following a single oral…
- Trial name
- NCT00778024
- Testing
- fluoxetine HCL 40 mg capsules
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Obesity, Overweight
A Cafeteria Based Study of Weight Gain Prevention
The dramatic rise in overweight and obesity during the past several decades can be explained by environmental changes that foster increased energy intake and decreased energy expenditure.
- Trial name
- Cafeteria (NCT00573482)
- Testing
- REDE, control
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
The Study Focus on no Specific Condition
Interpretation of Health News Items Reporting Results of Phase I/II (Non-randomized) Trials With or Without Spin by English-speaking Population
The main objective of this study is to compare the interpretation of health news items reporting results of phase I/II (non-randomized) trials with or without spin (i.e., distortion of research results).
- Trial name
- NCT03094104
- Testing
- News items with spin, News items without spin
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
no Condition Being Studied; tDCS Only in Healthy Subjects
Using tDCS to Enhance Learning of a New Walking Pattern
The ability to change walking patterns is important for daily tasks such as stepping over an obstacle. This change of walking pattern can occur in a strategic manner, i.e., consciously making one step longer or shorter.
- Trial name
- NCT03582904
- Testing
- tDCS
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Delaware
No Condition, Assessment of Healthy Volunteers
Immunometabolism of Exercise
This study aims to examine the effects of acute aerobic exercise and cardiorespiratory fitness on cellular metabolism of CD8+ T cells and regulatory T cells (Tregs) found in the peripheral blood of humans.
- Trial name
- IMEX (NCT07188389)
- Testing
- Acute exercise-moderate intensity, Acute effects-heavy intensity
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Houston
Hypovolemia, Fluid Loss
Acetated Ringer´s Solution in Experimental Hypovolemia
Intravenous fluids are often given to increase stroke volume and thereby improve global oxygen delivery. The effect is however often transient, but the effect of a fluid bolus on stroke volume and other hemodynamic variables over…
- Conditions
- Hypovolemia, Fluid Loss, Hemodynamic Instability
- Trial name
- Volu-Flow (NCT05705115)
- Testing
- Ringer acetate, Lower body negative pressure
- Where
- Norway
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
No Disease or Condition is Being Studied, Stress Psychological
Supporting Secondary School Student Wellbeing Through a Mobile App and Wearable Biofeedback
This study aims to investigate the effects of an app and wearable device on the wellbeing of secondary school students. The app will offer support for stress management, sleep improvement, and time management.
- Conditions
- No Disease or Condition is Being Studied, Stress Psychological, Overall Wellness
- Trial name
- EWSSS (NCT06294210)
- Testing
- Mobile app and wrist-worn monitor
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
No Specific Conditions
Acceptance and Commitment Therapy for Informal Caregivers of People With Dementia
Dementia has a major impact on people with dementia and their family. Informal caregivers of people with dementia are at higher risk of developing depressive symptoms compared to informal caregivers of people with other chronic…
- Trial name
- ACT-IC (NCT05064969)
- Testing
- Blended intervention based in acceptance and commitment therapy
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Positive Emotions, Mental Health
Reducing Symptoms of Depression, Stress and Anxiety and Enhancing Positive Mental Health: a Randomized-controlled Study of the Positive Emotions Training
Based on the results of the previously published paper "Positive Emotions Training (PoET) as an online intervention to improve mental health: a feasibility study" (Niemann et al., 2023) the goal of this study was to examine the…
- Conditions
- Positive Emotions, Mental Health, Intervention (Training) Condition, Randomized Controlled Study
- Trial name
- NCT06851637
- Testing
- PoET
- Where
- Germany
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Atherosclerosis, Atheroscleroses, Coronary
Detection of Coronary Artery Calcifications by Whole Blood Transcriptome Analyzed by Artificial InTelligence Algorithms
The goal of this observational study is to determine the diagnostic accuracy of peripheral whole blood transcriptomes analyzed by an artificial intelligence algorithm to detect the presence and extent of coronary calcification in…
- Conditions
- Atherosclerosis, Atheroscleroses, Coronary, Atherosclerotic Plaque
- Trial name
- CAC-TRAIT (NCT05619042)
- Where
- Argentina
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Santiago Gabriel Miriuka
Gender, Postoperative Pain
Acute Postthoracotomy Pain - Impact of Gender
Adequate analgesia in thoracic surgery is essential to prevent severe postoperative complications, especially respiratory problems.
- Conditions
- Gender, Postoperative Pain, Thoracotomy, Analgesia
- Trial name
- NCT03281213
- Testing
- Thoracotomy
- Where
- Austria
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Anesthesia, Neuroinflammation
Neuroinflammatory Biomarkers After General Anesthesia: A Comparison Study
This prospective, observational study investigates the impact of repeated general anesthesia exposure on neuroinflammatory biomarkers and neurotrophic factors.
- Conditions
- Anesthesia, Neuroinflammation, Cognitive Disorders
- Trial name
- NCT07388160
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Hepatocellular Carcinoma, Cholangiocarcinoma
Hepatobiliary Tumors Tissue Samples Acquisition
Hepatobiliary tumors have a poor prognosis and high individual heterogeneity, so it is of great significance to find important prognostic markers and then screen out specific subgroups of people; meanwhile, chronic hepatitis…
- Conditions
- Hepatocellular Carcinoma, Cholangiocarcinoma, Gallbladder Cancer, Biliary Tract Cancer
- Trial name
- NCT04445532
- Testing
- Gene expression analysis, Genomic analysis, Protein expression analysis
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Healthy
Evaluate the Migration Potential of Xeomin® Compared to Two Other Botulinum Toxin Type A Products
Xeomin® is a Botulinum neurotoxin type A preparation free of complexing proteins, i.e. free of bacterial proteins other than the active toxin. Injected into the muscle, Xeomin® causes local weakening.
- Trial name
- NCT00515944
- Testing
- Botulinum neurotoxin type A, free of complexing proteins
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Merz Pharmaceuticals GmbH
Obesity and Overweight
Reduction in Consumption of Sweetened Beverages on Weight, Body Composition and Blood Pressure in Young Adults
The impact of reduction in consumption of caloric and no caloric sweetened beverages on: weight body composition blood pressure young adults
- Trial name
- NCT02347267
- Testing
- Caloric and non-caloric SSBS reduction, Caloric SSBS reduction
- Where
- Mexico
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Healthy
Bioequivalence Study of Fosinopril 40mg Tablets Under Fasting Conditions
The objective of this study is to compare the relative bioavailability of fosinopril sodium 40 mg tablets (Ranbaxy Laboratories Limited, Lot No. 1238312) with that of Monopril® in healthy adult subjects under fasting conditions.
- Trial name
- NCT00776334
- Testing
- Fosinopril 40mg Tablets
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Attention - no Condition is Being Assessed - Healthy Adults
Investigation of Locus Coeruleus Function in Sustained Attention
The norepinephrine-producing locus coeruleus (LC) is thought to be central to a wide array of cognitive functions, like attention and goal pursuit, and has been implicated in dysfunctions including attention deficit hyperactivity…
- Trial name
- LC (NCT06041048)
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Davis