Clinical trials: no Conditions
No Disease or Condition is Being Studied
Optimizing Operational Parameters for Diagnostic Vitrectomy
Single-center ex-vivo study using blood samples from healthy donors processed through a 25-gauge vitrectomy system. The study compares four combinations of operational parameters (vacuum pressure and cut rate) to evaluate their…
- Trial name
- CELLVIT (NCT07408466)
- Testing
- Simulated vitrectomy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Chronic Hepatitis C
Daily-Dose Consensus Interferon and Ribavirin: Efficacy of Combined Therapy
This Phase 3 clinical study is designed to evaluate the safety, tolerability, and efficacy of two dose levels of Infergen (interferon alfacon-1, CIFN) plus Ribavirin administered daily for 48 weeks and no treatment in patients…
- Trial name
- NCT00086541
- Testing
- Daily Infergen (Interferon Alfacon-1, CIFN) (9 or 15 µg) + Ribavirin (1000-1200 mg, based on body weight) PO Daily for up to 48 wks
- Volunteers
- 515 people
- Sponsor
- Bausch Health Americas, Inc.
no Specific Condition Targeted
Assessment of the Benefit of the Mobility Assistance System (SAM) on Transfer Independence for a Reimbursement Request
This is a randomized, cross-over, multi-center, intention-to-treat, open-label study to assess the impact of the SAM Ergonom light (SAM) device on independence when transferring from the supine to the sitting position at the edge…
- Trial name
- SAM-24 (NCT06698653)
- Testing
- SAM device (experimental): a removable structure, fixed to the horizontal frame of the medical bed, equipped with a handle to assist the sitting-up process, Over bed pole hoist (control device)
- Where
- 3 sites in France
- Volunteers
- 54 people
- Sponsor
- WINNCARE
Individual, Category, and No-label Conditions
Infant and Parent Shared Book Reading
This work is guided by two specific aims and is expected to result in a better understanding of the effectiveness of shared book reading as a tool for supporting parent-infant interactions and infant learning across the first…
- Trial name
- NCT04337372
- Testing
- Effects of shared book reading: Labels
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Florida
Solid Tumors, CNS Tumors
Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options
This is an open-label, Phase 1/2 multicenter dose escalation study in pediatric patients with relapsed or refractory extracranial solid tumors (Phase 1), with additional expansion cohorts (Phase 2) in patients with primary brain…
- Trial name
- STARTRK-NG (NCT02650401)
- Testing
- Entrectinib
- Where
- 26 sites in United States, Canada and 7 more
- Volunteers
- 69 people
- Sponsor
- Hoffmann-La Roche
Acute Myocardial Infarction
A Safety/Efficacy Study of Intra-coronary Tenecteplase During Balloon Angioplasty to Treat Heart Attacks
The primary objective of this study is to gather preliminary data regarding the angiographic efficacy of the administration of low-dose adjunctive intracoronary (IC) tenecteplase during balloon angioplasty for heart attacks.
- Trial name
- ICE T-TIMI 49 (NCT00604695)
- Testing
- Tenecteplase, Sterile Saline
- Where
- 8 sites in United States
- Volunteers
- 40 people
- Sponsor
- C. Michael Gibson, MS, MD
COPD
Dexmeditomedine Versus No Sedation in Management of Agitation in COPD Patients Receiving Noninvasive Ventilation
The aim is to compare sedation using dexmedetomidine to sedation -free approach in management of agitated COPD patients receiving NIV
- Trial name
- NCT05774145
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
No Condition Salivary Alpha Amylase
Salivary Alpha Amylase as a Biomarker of Transdermal Vagus Nerve Stimulation
The proposed project tests the hypothesis that salivary alpha amylase concentration is a reliable biomarker of the effect of transdermal vagus nerve stimulation (tVNS) in humans.
- Trial name
- NCT03854539
- Testing
- Transdermal Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Arkansas Tech University
Age-Related Macular Degeneration
Photodynamic Therapy in Occult-Only Lesions (POOL)
Age related macular degeneration is the leading cause of blindness for people over 50 in the western world. Blood vessels which start to grow form a lesion in the back of the eye.
- Trial name
- NCT00135837
- Testing
- Verteporfin for injection
- Where
- Switzerland
- Volunteers
- 202 people
- Sponsor
- Novartis
no Conditions
Speech Perception in Noise in Children With ADHD
We are going to assess an ability of speech perception in voice in children diagnosed with ADHD (Attention Deficit Hyperactivity Disorder), comparing to normal control group.
- Trial name
- ME (NCT05624372)
- Testing
- hearing and cognitive assessment
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Healthy, no Evidence of Disease, Hot Flashes
Evaluation of SAMe for Hot Flashes
RATIONALE: S-adenosyl-L-methionine may help relieve hot flashes in women based upon its ability to potentially modulate serotonin.
- Trial name
- SAMe (NCT01140646)
- Testing
- S-adenosyl-L-methionine disulfate p-toluene-sulfonate, questionnaire administration, quality-of-life assessment
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mayo Clinic
Chronic Rhinosinusitis (Diagnosis), Nasal Polyps
NO Measurements in Screening for Asthma and OSA, in Patients With CRSwNP
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a condition resulting in varying degrees of nasal congestion, nasal secretion, facial pain and reduced or absent sense of smell.
- Conditions
- Chronic Rhinosinusitis (Diagnosis), Nasal Polyps, Asthma, Obstructive Sleep Apnea
- Trial name
- NCT03963648
- Testing
- Fractioned Exhaled Nitrogen Oxide measurements
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Christian von Buchwald
Stroke, Ischemic, Atrial Fibrillation
Atrial CMR in Patients With CVA of Unknown Source and no Known AF
This research study will investigate a new method for identifying which patients should be offered blood thinners or therapies to reverse the underlying causes after stroke.
- Trial name
- CARM-AF (NCT04555538)
- Testing
- Cardiac MRI
- Where
- 3 sites in United Kingdom
- Volunteers
- 92 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cervical Intraepithelial Neoplasia 3
Safety and Efficacy of GX-188E DNA Therapeutic Vaccine Administered by Electroporation After Observation
This study is to follow up on the change of immune response by measuring HPV type 16/18 E6 and E7 specific T cell response and lesion condition in subjects who have administered in DNA-based therapeutic vaccine.
- Trial name
- NCT02100085
- Testing
- GX-188E
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- Genexine, Inc.
Sinus Node Disease
To Pace or Not to Pace in Sinus Node Disease
Optimal pacing strategy for patients with SND is still unknown, although several publications in the past years demonstrated a deleterious effect of ventricular pacing.
- Trial name
- OPTIMIST (NCT02485093)
- Testing
- Septal ventricular pacing, VIP
- Where
- France
- Volunteers
- 215 people
- Sponsor
- Abbott Medical Devices
Low Back Pain
Effectiveness of the SelfBack-App in Preventing and Treating Low Back Pain Versus no Intervention: a Non-randomized Clinical Trial
Low back pain (LBP) is the leading cause of disability worldwide and represents a major burden for both individuals and healthcare systems.
- Trial name
- NCT07785804
- Testing
- Selfback app, No Interventions
- Where
- Belgium
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Overweight and Obesity
Go/No-Go Intervention for Weight Loss
The purpose of this study is to assess the effect of a food-specific Go/No-Go (GNG) computerized training task on weight loss, food evaluation, and disinhibition in a population of overweight and obese individuals.
- Trial name
- NCT04624087
- Testing
- food-specific go/no-go computerized training, nonfood-specific go/no-go computerized training
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Minnesota
Low Back Pain
Graded Activity Versus Supervised Exercises in Patients With Chronic Non-specific Low Back Pain
The purpose of this study is to compare the efficacy of graded activity program and supervised exercise on pain, functional disability, quality of life, global perceived effect, return to work, physical activity, physical…
- Trial name
- NCT01719276
- Testing
- Graded Activity, Supervised Exercises
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- University of Sao Paulo
Cancer Survivor, Central Obesity
Physical Activity in Reducing Metabolic Dysregulation (MetD) in Obese Latina Breast Cancer Survivors
This randomized phase II trial studies how well physical activity works in reducing metabolic dysregulation in obese Latina breast cancer survivors.
- Conditions
- Cancer Survivor, Central Obesity, No Evidence of Disease
- Trial name
- NCT03120390
- Testing
- Best Practice, Exercise Intervention, Laboratory Biomarker Analysis
- Where
- United States
- Sponsor
- University of Southern California
Critical Lower Limb Ischemia, Type-2 Diabetes Mellitus
Safety and Efficacy Study of Autologous Bone Marrow Aspirate Concentrate for No-Option Critical Limb Ischemia
The aim of the presented clinical trial is to evaluate a hypothesis, that BMAC prepared from bone marrow aspirate and injected intramuscularly into ischemic areas of the lower extremity in patients with diabetes mellitus type…
- Trial name
- DIALEG (NCT01818310)
- Testing
- Group A: Intramuscular, Group B: Intraarterial, Group C: Intravenous
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- University Hospital Ostrava