Clinical trials: no Conditions
No-Reflow, STEMI
No-Reflow in Patients With STEMI After Intracoronary Tirofiban After Opening of the Track
This study aims to assess the no-reflow in patients with STEMI after intracoronary glycoprotein IIb/IIIa inhibitors after opening of track in thrombus.
- Conditions
- No-Reflow, STEMI, Intracoronary, Tirofiban
- Trial name
- NCT06966674
- Testing
- Intracoronary tirofiban, Saline 0.9%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Metastatic or Recurrent Head and Neck Squamous Cell Cancer
Phase II Trial of Carboplatin, 5-FU and Cetuximab in Elderly Fit (no Frailty) Patients With Recurrent/Metastatic HNSCC
The aim of the trial is to evaluate the clinical benefit (efficacy, safety, preservation of autonomy) of cetuximab-carboplatin-5FU combination as first line treatment of recurrent or metastatic head and neck squamous cell…
- Trial name
- ELANFIT (NCT01864772)
- Testing
- Carbo, 5FU, Cetuximab
- Where
- 2 sites in France
- Volunteers
- 85 people
- Sponsor
- Groupe Oncologie Radiotherapie Tete et Cou
Musculoskeletal Injury
Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries
Musculoskeletal (MSK) injuries, including limb injuries, are the most common cause for Emergency Department (ED) visits for children with pain.
- Trial name
- No OUCH (NCT03767933)
- Testing
- Ibuprofen, Acetaminophen, Hydromorphone
- Where
- 6 sites in Canada
- Volunteers
- 710 people
- Sponsor
- University of Alberta
Hepatitis B, Chronic
A Study of the Safety and Efficacy of Pegylated Inferferon Alfa-2b (PEG-Intron™) Versus Pegylated Interferon Alfa-2a (PEGASYS™) in Participants With Chronic Hepatitis B (P08450)
This study is being done to compare the safety and efficacy of PEG-Intron™ to that of PEGASYS™ in participants with chronic hepatitis B (hepatitis B envelope antigen [HBeAg] positive or negative) who have not previously been…
- Trial name
- NCT01641926
- Testing
- PEG-Intron™, PEGASYS™
- Volunteers
- 402 people
- Sponsor
- Merck Sharp & Dohme LLC
There is no Disease the Study Focus on Facial Index in Relation to RED
Maxillary Anterior Teeth and Facial Index Parameters in Correlation With Recurring Esthetic Dental Proportion
The goal of this cross-sectional study is to state the inter relation between anthropometric parameters of pristine maxillary anterior teeth and facial index and their correlation with recurring esthetic dental proportion (RED)…
- Trial name
- RED (NCT06812468)
- Testing
- Bellus 3D smart application, Medit i-700 intraoral scanner
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Ventricular Assist Device
Low Psoas Index and Cardiac Assistance: No Excess Mortality at D28 Post Implantation
The frailty syndrome is important to consider in perioperative cardiac assistance. One of its components is the patient's sarcopenia. This can be assessed by measuring the size of the psoas muscle.
- Trial name
- VAD (NCT05612555)
- Where
- France
- Volunteers
- 65 people
- Sponsor
- University Hospital, Strasbourg, France
Infection, Bacterial Infection
Procalcitonin Level to Discontinue Antibiotics on ICU Patients With no Obvious Site of Infection
The purpose of this study is to test whether a U.S. Food and Drug Administration (FDA) approved laboratory test (PCT Kryptor) can help doctors make better decisions on the need for antibiotic therapy in ICU patients with…
- Conditions
- Infection, Bacterial Infection, Sepsis
- Trial name
- NCT00407147
- Testing
- Procalcitonin assay - B.R.A.H.M.S PCT sensitive Kryptor
- Where
- 3 sites in United States
- Volunteers
- 11 people
- Sponsor
- Brahms AG
Intermittent Claudication
Effect of NCX4016 on Walking Distance in Patients With Peripheral Arterial Occlusive Disease (PAOD)
Peripheral arterial disease (PAD) is almost invariably associated with a generalized atherosclerotic involvement of the arterial tree and endothelial dysfunction.
- Trial name
- NCT01256775
- Testing
- NCX-4016
- Where
- Italy
- Volunteers
- 442 people
- Sponsor
- NicOx Research Institute S.r.l.
Atrium; Fibrillation, Chronic Kidney Diseases
Vitamin K AntagonISt, Factor Xa Inhibitor or No Anticoagulation in Atrial Fibrillation and DIalytic End-stage Renal DiseasE (VISIONAIRE)
VISIONAIRE (Vitamin K AntagonISt, Factor Xa Inhibitor Or Nothing In Atrial Fibrillation And DIalytic End-stage Renal DiseasE) trial will be a prospective randomized open-label with blinded endpoint adjudication trial including…
- Trial name
- VISIONAIRE (NCT06402851)
- Testing
- Anticoagulant Oral
- Where
- 6 sites in Brazil
- Volunteers
- 1,500 people
- Sponsor
- Hospital Sirio-Libanes
Hepatitis C, Chronic
Interferon α 2b Pharmacovigilance Study
Multicenter prospective follow-up of a not controlled chronic hepatitis C genotypes 2/3 patients cohort with treatment indication with interferon α 2b and ribavirin for 24 weeks, and the verification of sustained virological…
- Trial name
- NCT01841775
- Testing
- interferon α 2b + ribavirin
- Where
- 2 sites in Brazil
- Volunteers
- 85 people
- Sponsor
- The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz)
No Condition, Brain GABA-B Function
GABA-B Receptor Function in Healthy Volunteers
There are several developing lines of evidence suggesting that brain receptors called GABA-B receptors play a significant role in addiction and its treatment.
- Trial name
- NCT01563224
- Testing
- Baclofen 10mg, Baclofen 60mg
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Imperial College London
STEMI
CHA2DS2-VASc Score as a Predictor of Thrombus Burden and Clinical Outcomes in Patients Undergoing PPCI.
Aim of the work is to evaluate the use CHA2DS2-VASc score in predicting no-reflow phenomenon and its impact on short term primary percutaneous coronary intervention outcomes (in-hospital mortality) and long term (6 months)…
- Trial name
- NCT04565808
- Testing
- primary percutaneous coronary intervention
- Volunteers
- 184 people
- Sponsor
- Assiut University
NO CONDITIONS
Improving Ultrasound Based Prediction of Delivery Mode
The progress of labour is traditionally determined by regular vaginal examinations (VEs) to assess the cervix (neck of the womb) and the baby's head position.
- Trial name
- NCT04635410
- Testing
- ULTRASOUND IMAGING
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Lymphoma
Interferon Alfa-2b Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Hodgkin's Disease or Non-Hodgkin's Lymphoma
RATIONALE: Interferon-alfa may interfere with the growth of cancer cells. Giving interferon-alfa following chemotherapy and peripheral stem cell transplantation may be an effective treatment for Hodgkin's disease or non-Hodgkin's…
- Trial name
- NCT00003924
- Testing
- recombinant interferon alfa
- Where
- 2 sites in France, United Kingdom
- Volunteers
- 360 people
- Sponsor
- Lymphoma Study Association
General Population (no Specific Condition or Disease)
Brain Function Messures of a Psychological Flexibility Skills Training Based on ACT Over Disordered Eating Behaviors
Overweight and obesity are an increasing tendencies worldwide. Disordered Eating Behaviors (DEBs) are feeding dynamics commonly present on them, as in Feeding Disorders (FD).
- Trial name
- FLEXEAT (NCT07492056)
- Testing
- A Psychological Flexibility Skills Training based on ACT.
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Postoperative Pain
0.15 mg Spinal Morphine vs. no Treatment for Morphine Requirement After VATs.
Postoperative pain after Video-assisted Thoracoscopic Surgery (VAT) is still debating. Therefore the investigators conduct a study comparing 0.15 mg spinal morphine and control group in term of analgesia.
- Trial name
- NCT01979354
- Testing
- Spinal morphine
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Critical Limb Ischemia
PROMISE International
The objective of this post-market study is to evaluate the safety and effectiveness of the LimFlow System in creating a below-the-knee arterio-venous fistula for venous arterialization in subjects with critical limb ischemia.
- Trial name
- NCT03321552
- Testing
- Percutaneous deep vein arterialization, LimFlow System
- Where
- 12 sites in Austria, Germany and 3 more
- Volunteers
- 34 people
- Sponsor
- LimFlow SA
No Condition : to Establish Reference Serum Serotonin Levels in a Control Cohort
Analysis of Peripheral Serotonin Levels in a Control Cohort
The goal of this observational study is to measure serotonin levels in in a control cohort. The main question aims to determine the mean serum serotonin level in a cohort of adult controls, based on age and sex.
- Trial name
- ASPECT (NCT06910774)
- Testing
- Dosage of serotonin and tryptophan metabolites levels in serum
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Sud Francilien
Peripheral Arterial Disease
Circulating Anti-Beta2-glycoprotein Antibodies and Endothelial Dysfunction
Circulating anti-beta2-glycoprotein antibodies have been associated with coronary artery disease and peripheral arterial disease.
- Trial name
- NCT01822990
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Getafe
Amputation, Blood Loss
Pneumatic Tourniquet Versus no Tourniquet in Transfemoral Amputation
Lower extremity amputation patients represent a frail group of patients with extensive comorbidity. The most common indication of amputation is ischemia, infection and concomitant ischemic pain due to underlying chronic disease…
- Trial name
- NCT05550623
- Testing
- Tourniquet
- Where
- Denmark
- Volunteers
- 124 people
- Sponsor
- University of Southern Denmark