Clinical trials: psoriasis
Plaque Psoriasis
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of ASC50 Tables in Healthy Participants and Participants With Plaque Psoriasis
This is a phase I, randomized, double-blind, placebo-controlled, single and multiple ascending dose study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, food effect of ASC50 tablets in healthy adult…
- Trial name
- NCT07024602
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Ascletis Pharma (China) Co., Limited
Psoriasis
A Study to Evaluate Efficacy and Safety of HS-10374 for Moderate to Severe Plaque Psoriasis
This study has been designed to explore the clinical efficacy and safety of HS-10374 in the treatment of moderate to severe plaque psoriasis.
- Trial name
- NCT06077331
- Testing
- HS-10374 tablets 1mg, HS-10374 tablets 5mg
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Hansoh BioMedical R&D Company
Plaque Psoriasis
A Observational Study to Evaluate Deucravacitinib in Patients With Moderate Plaque Psoriasis in China
The purpose of this study is to collect and evaluate real-world data on the effectiveness of deucravacitinib treatment in adults with moderate plaque psoriasis in China.
- Trial name
- ADMIRE (NCT06512337)
- Testing
- Deucravacitinib
- Where
- 5 sites in China
- Volunteers
- 153 people
- Sponsor
- Bristol-Myers Squibb
Ultrasound in Patients With Atypical Shape of Psoriasis
Ultrasound Study of Entheses and Small Joints of Hands and Feet in Patients With Atypical Form of Psoriasis
Systematic study of the ultrasound infringements of tendons chest expanders of entheses the most involved in spondylarthropathies and small joints of hands and feet in expanding patients of psoriasis to estimate if there is an…
- Trial name
- ECHOPSO (NCT02899429)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Brest
Plaque Psoriasis
Evaluate Safety/Efficacy of Two Treatment Regimens for Vectical™ Ointment & Clobex® Spray for Moderate Plaque Psoriasis
This clinical trial will evaluate the efficacy and safety of Clobex® (clobetasol propionate) Spray 0.05% and Vectical™ (calcitriol) Ointment 3 µg/g over a four week period of use in one of two different regimens: 1.
- Trial name
- NCT00988637
- Testing
- Vectical™ Ointment weekdays and Clobex® Spray weekends regimen, Clobex® Spray morning and Vectical™ Ointment evening regimen
- Where
- 6 sites in United States, Canada
- Volunteers
- 138 people
- Sponsor
- Galderma R&D
Chronic Plaque Psoriasis
A Study to Assess the Efficacy and Safety of Alefacept in Psoriasis Patients for Whom Conventional Treatment is Ineffective or Inappropriate
To assess the efficacy and safety of Alefacept compared to placebo for the treatment of Chronic Plaque Psoriasis in patients for whom conventional therapies are ineffective and inappropriate
- Trial name
- NCT00673556
- Testing
- alefacept
- Where
- 34 sites in United States, Austria and 3 more
- Volunteers
- 195 people
- Sponsor
- Astellas Pharma Inc
Psoriasis
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants
The purpose of this study is to evaluate the efficacy and safety of guselkumab in pediatric participants aged greater than or equal to 6 through less than 18 years with chronic plaque psoriasis.
- Trial name
- PROTOSTAR (NCT03451851)
- Testing
- Guselkumab, Etanercept
- Where
- 39 sites in United States, Australia and 7 more
- Volunteers
- 120 people
- Sponsor
- Janssen Research & Development, LLC
Healthy, Atopic Dermatitis Eczema
Development of a Method to Measure mRNA Levels in Skin Samples
The purpose of this study was to develop a non-invasive method to measure mRNA levels using tape stripping on the skin of patients with psoriasis and patients with atopic dermatitis.
- Conditions
- Healthy, Atopic Dermatitis Eczema, Psoriasis
- Trial name
- NCT04537468
- Testing
- Skin squame collection, Tape strip collection, Tape strip and skin biopsy collection
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Nail Psoriasis
Observational Study in Patients With Nail Psoriasis Treated With Enstilar® to Assess the Severity Change and the Quality of Life
Observational, prospective and multicentre study to evaluate the effectiveness of calcipotriene and betamethasone dipropionate aerosol foam (Cal / BD), prescribed according to clinical practice and following the Product Data…
- Trial name
- ENUPS (NCT04380597)
- Testing
- Calcipotriene and betamethasone dipropionate aerosol foam
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Angeles Florez
Psoriasis Vulgaris
Safety and Effectiveness of Combined LED Light for the Treatment of Mild to Moderate Plaque Type Psoriasis Vulgaris
The purpose of this study is to investigate whether light therapy can help improve plaque psoriasis. This is a study based on a new medical device. The device produces its light from light emitting diodes.
- Trial name
- NCT03507946
- Testing
- Dermawrap - combined 460nm, 633nm and 830nm LED therapy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ismart
Atopic Dermatitis, Psoriasis
Disease Trajectories and Anti-cytokine Response Signatures in Atopic Dermatitis and Psoriasis
The clinical study investigates the long-term course of disease in patients with chronic inflammatory skin diseases (atopic eczema and psoriasis) and the impact of tarheted therapies on the clinical and molecular level.
- Conditions
- Atopic Dermatitis, Psoriasis, Healthy
- Trial name
- DiTrAP (NCT03361215)
- Testing
- Biosampling for molecular analysis
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Chronic Plaque Psoriasis
Safety and Tolerability of Repeat Courses of IM Alefacept
The purpose of this study is to determine whether repeat courses of alefacept, administered intramuscularly, are safe when given to chronic plaque psoriasis patients who are receiving standard dermatology treatments.
- Trial name
- NCT00233662
- Testing
- Alefacept
- Where
- 46 sites in United States, Austria and 7 more
- Volunteers
- 400 people
- Sponsor
- Biogen
Psoriasis
A Study on the Safety of Deucravacitinib Exposure in Pregnant Women and Their Offspring
This observational study aims to assess pregnancy and infant outcomes among pregnant women with psoriasis who have been exposed to deucravacitinib treatment in the USA.
- Trial name
- NCT06710470
- Testing
- Deucravacitinib, Systemic psoriasis medications, No systemic medications
- Where
- United States
- Volunteers
- 833 people
- Sponsor
- Bristol-Myers Squibb
Plaque Psoriasis
A Study to Assess Patient-Reported Wellbeing Using Tildrakizumab in a Live Setting
The main purpose of this study to investigate the relationship between clinical symptoms and quality of life (QoL) in participants who receive Tildrakizumab in the frame of clinical routine for the treatment of moderate to severe…
- Trial name
- NCT06488170
- Testing
- Tildrakizumab
- Where
- 7 sites in Czechia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Almirall, S.A.
Skin Lesions, Melanocytic Nevi
Evaluating an Artificial Intelligence Tool to Help Primary Care Doctors Diagnose Skin Conditions.
This study aims to determine if an artificial intelligence (AI) medical device can help primary care doctors more accurately identify and manage various skin conditions.
- Conditions
- Skin Lesions, Melanocytic Nevi, Melanoma (Skin Cancer), Basal Cell Carcinoma of Skin
- Trial name
- LegitHealth PH (NCT07428941)
- Testing
- AI-based medical device for aided diagnosis in dermatological conditions
- Where
- Spain
- Volunteers
- 9 people
- Sponsor
- AI Labs Group S.L
Psoriasis, Sleep Apnea, Obstructive
Efficacy and Safety of Adalimumab in Patients With Psoriasis and Obstructive Sleep Apnea
This study will evaluate the effect and safety of adalimumab in approximately 20 subjects with mild to moderate psoriasis and sleep apnea and will be conducted in one treatment center located in Montreal.
- Trial name
- NCT01181570
- Testing
- Adalimumab
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Innovaderm Research Inc.
Psoriasis
Effect of Long-term Psoriasis on Patients' Life - CORONATE
Psoriasis, is an inflammatory chronic skin disease which has a heavy physical and psychosocial impact on participant's life. This is a study to finalize and validate a questionnaire to assess the long-term effect of long-term…
- Trial name
- CORONATE (NCT05555953)
- Where
- 15 sites in Italy
- Volunteers
- 543 people
- Sponsor
- AbbVie
Plaque Psoriasis
A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants With Moderate to Severe Plaque Psoriasis
The purpose of this pediatric study is to evaluate the drug levels, efficacy and safety of Deucravacitinib in children and adolescent participants aged 4 to <18 years with moderate to severe plaque psoriasis.
- Trial name
- NCT04772079
- Testing
- Deucravacitinib
- Where
- 65 sites in Argentina, Australia and 11 more
- Volunteers
- 153 people
- Sponsor
- Bristol-Myers Squibb
Plaque Psoriasis
Evaluation of TWEAK in Plaque Psoriasis and Psoriatic Arthritis Patients
Psoriasis vulgaris is associated with significant comorbidity including depression, increased risk of cardiovascular events, diminished quality of life, as well as overall increased mortality.
- Trial name
- NCT06370156
- Testing
- Adalimumab
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Psoriasis
A Randomized, Open, Parallel, Controlled, Multi-center, Interventional, Cross-sectional Study to Evaluate the Detection Rate of Psoriatic Arthritis in Korean Moderate-to-severe Psoriasis Patients, With or Without Active Screening for Arthritis in Psoriasis (ASAP Study)
This was a randomized, open, parallel, controlled, multi-center, interventional, cross-sectional study to evaluate the detection rate of Psoriatic arthritis (PsA) in Korean moderate to severe Psoriasis (PsO) patients with or…
- Trial name
- ASAP (NCT05758402)
- Testing
- Routine practice group, EARP group
- Where
- 15 sites in South Korea
- Volunteers
- 368 people
- Sponsor
- Novartis Pharmaceuticals
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