Clinical trials: r-axSpA
Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA)
Biomarkers in Ankylosing Spondylitis
In this study, we aimed to compare serum PGRN(progranulin) and TNF-α levels in AS patients with healthy controls and to determine the relationship between TNF-α inhibitor use and PGRN levels in AS patients.
- Trial name
- NCT07117344
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Axial Spondyloarthritis (axSpA), Ankylosing Spondylitis (AS)
Evaluation of the Expression and Functions of the KIR3DL2 Receptor and the Anti-inflammatory Activity of IPH4102 in Blood Samples
the main objectives are 1. to study the pathophysiological role of KIR3DL2 in axSpA and its relationship with Th17 immunity in HLA-B27 + and HLA-B27- patients and 2.
- Trial name
- KIR3DL2 (NCT03322618)
- Testing
- blood samples
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Rheumatic Diseases, Rheumatoid Arthritis (RA)
Clinical Assessment for Rheumatologic Disease - Research and Advancement in Safety and Efficacy
The CARe RAiSE project represents a pioneering translational initiative aimed at advancing precision medicine in the treatment of autoimmune rheumatic diseases.
- Conditions
- Rheumatic Diseases, Rheumatoid Arthritis (RA), Giant Cell Arteritis (GCA), Psoriatic Arthritis (PsA)
- Trial name
- CARe RAiSE (NCT07150000)
- Testing
- Ex Vivo Assay
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Bonn
Axial Spondylarthritis (axSpA), Myofascial Trigger Point Pain (MTrP)
Ultrasonographic Assessment of Thoracolumbar Fascia in AxSpA and Controls With Trigger Point Evaluation
The goal of this observational study is to evaluate whether changes in the thoracolumbar fascia (TLF)-a connective tissue in the lower back-are related to pain and disease severity in patients with axial spondyloarthropathy…
- Conditions
- Axial Spondylarthritis (axSpA), Myofascial Trigger Point Pain (MTrP), Ultrasound Exams
- Trial name
- NCT06978374
- Testing
- Sonographic examination of thoracolumbar fascia, manual examination of MTrP
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Ankara University
Axial Spondyloarthritis (AxSpA)
Retrospective Case-Control Study for Developing an Artificial Intelligence (AI) Tool for Lesion Detection Using Magnetic Resonance Imaging (MRI) and Clinical Variables for Early Diagnosis of Axial Spondyloarthritis (axSpA)
The goal of this observational study is to develop and validate an Artificial Intelligence (AI) tool that allows the lesion detection and early diagnosis of axial spondyloarthritis (axSpA) based on Magnetic Resonance Imaging…
- Trial name
- InnovaDetect (NCT06591481)
- Where
- 7 sites in Jordan, Saudi Arabia and 2 more
- Volunteers
- 925 people, healthy volunteers welcome
- Sponsor
- Ángel Alberich Bayarri
Axial Spondyloarthritis, Ankylosing Spondylitis
axSEND: Exploring Immune and Microbiota Effects of a Partial Enteral Nutrition Diet in Axial Spondyloarthritis
People with axial spondyloarthritis (axSpA) often have intestinal inflammation and intestinal microbiome dysbiosis, with some similarities to Crohn's-like inflammatory bowel disease (IBD) gut inflammation.
- Conditions
- Axial Spondyloarthritis, Ankylosing Spondylitis, Inflammation, Dysbiosis
- Trial name
- axSEND (NCT06460805)
- Testing
- Partial enteral nutrition
- Where
- 2 sites in United Kingdom
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde