Clinical trials: rTMS
Bulimia Nervosa, Anorexia Nervosa
Repetitive Transcranial Magnetic Stimulation of the DMPFC for Anorexia and Bulimia: an Open-Label Case Series
This project proposes to perform a pilot study of fMRI targeted Dorsomedial Prefrontal Cortex repetitive transcranial magnetic stimulation (DMPFC-rTMS) on individuals diagnosed with Bulimia Nervosa (BN) and Anorexia Nervosa (AN).
- Trial name
- NCT04409704
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Chronic Pain
Mechanistic Study of Personalized rTMS in Chronic Pain
Previous research has demonstrated that repetitive magnetic brain stimulation can be an effective adjunctive treatment for several conditions, including chronic pain.
- Trial name
- PRECISE-Pain (NCT07266103)
- Testing
- Classical repetitive trancranial magnetic stimulation to M1, Personalized Target Arm
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Aalborg University
Depressive Syndrom
Real-World NeuroModulate: Investigating Non-Invasive Brain Stimulation for Neuropsychiatric Disorders at TUM
In this study, patients diagnosed with a depressive syndrome and with a clinical indication for treatment will receive an acute course of transcranial magnetic stimulation (TMS).
- Trial name
- NCT07420322
- Testing
- iTBS Treatment
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Recurrent Pregnancy Loss, Overweight , Obesity
Effects of High-frequency Left Dorsolateral Prefrontal rTMS on Heart-brain Coupling in Women With Recurrent Pregnancy Loss and Elevated BMI
This randomized, sham-controlled mechanistic trial will examine whether a single session of high-frequency repetitive transcranial magnetic stimulation, rTMS, applied to the left dorsolateral prefrontal cortex can modify…
- Conditions
- Recurrent Pregnancy Loss, Overweight , Obesity, Heart-Brain Coupling
- Trial name
- NEURO-CARD-BMI (NCT07561931)
- Testing
- Real repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shenyang Medical College
Depression, Depression - Major Depressive Disorder
Comparing Outcomes of Theta Burst Stimulation in Depression Using Advanced PET Imaging
The proposed project will investigate the neurobiological mechanisms of accelerated intermittent Theta Burst Stimulation (iTBS) in major depressive disorder (MDD) using an advanced multimodal imaging approach.
- Conditions
- Depression, Depression - Major Depressive Disorder, Depressive Episode, Major Depressive Disorder (MDD)
- Trial name
- NCT07620288
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Hallucinations, Schizophrenia
Multimodal MRI-guided rTMS to Treat Refractory Hallucinations
The efficacy of neuro-navigated rTMS for patients with schizophrenia suffering from drug-resistant multisensory hallucinations will be tested by the implementation of a double-blind randomized controlled trial (RCT) This study…
- Conditions
- Hallucinations, Schizophrenia, Perceptual Disorders
- Trial name
- MULTIMODHAL (NCT01373866)
- Testing
- MagPro X100 repetitive Transcranial Magnetic Stimulation
- Where
- 2 sites in France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Lille
Suspected Non-Alzheimer Disease Pathophysiology (SNAP)
Cognitive Effects of Theta-burst Stimulation (TBS) in Suspected Non-Alzheimer Disease Pathophysiology (SNAP)
This is a pilot study to identify a homogeneous cohort of pathologically specific dementia with SNAP for clinical trial of brain stimulation.
- Trial name
- SNAP (NCT05440110)
- Testing
- active and active TBS
- Where
- Taiwan
- Volunteers
- 17 people
- Sponsor
- Chang Gung Memorial Hospital
The Effects of Cerebellar rTMS on the Brain
The Effects of Cerebellar rTMS on Brain Activity
Swallowing function is controlled by two swallowing centres (one on each half of the brain). There is a dominant and non-dominant swallowing centre.
- Trial name
- NCT05736380
- Testing
- Cerebellar rTMS
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Depressive Disorder
The Antidepressant Effect of Repetitive Transcranial Magnetic Stimulation (rTMS)Compared to ECT
The aim of the present study is to compare the antidepressant effect of electroconvulsive therapy ( ECT) with that of low frequency repetitive transcranial magnetic stimulation of the right prefrontal cortex.
- Trial name
- NCT00299403
- Testing
- Right prefrontal lowfrequency ( 1 hz) rTMS., Electroconvulsive therapy (ECT)
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Major Depressive Disorder, Depression
rTMS for MDD: 5.5cm Rule vs. F3 Targeting
The purpose of this study is to examine the effects of different treatment locations using repetitive transcranial magnetic stimulation (rTMS) to treat major depressive disorder.
- Trial name
- NCT03378570
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Nicholas Trapp
Parkinson's Disease
Sequence Effect in Parkinson's Disease
This study will explore sequence effect, a fatigue or tiredness commonly seen in patients with Parkinson's disease after they have been doing the same thing for a while.
- Trial name
- NCT00431366
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Orthopaedic Trauma
rTMS for Orthopaedic Trauma Patients
This study evaluates an accelerated schedule of theta-burst stimulation using a transcranial magnetic stimulation device for orthopaedic trauma patients.
- Trial name
- NCT03924024
- Testing
- Accelerated intermittent theta burst treatment
- Where
- United States
- Sponsor
- Stanford University
Postpartum Depression (PPD)
SAINT in Postpartum Depression (PPD)
This study is a large, multi-site clinical trial testing whether Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT), a fast-acting form of repetitive transcranial magnetic stimulation (rTMS), can more effectively…
- Trial name
- NCT07210255
- Testing
- SAINT Neuromodulation System
- Where
- 4 sites in United States
- Volunteers
- 192 people
- Sponsor
- Magnus Medical
Healthy Adults
Efficacy and Safety of Repetitive Transcranial Magnetic Stimulation and Expressive Writing for Post-Traumatic Stress
The goal of this clinical trial is to learn if a combined treatment using repetitive transcranial magnetic stimulation (rTMS) and expressive writing works to reduce symptoms of post-traumatic stress in adults.
- Trial name
- NCT07567261
- Testing
- Repetitive Transcranial Magnetic Stimulation, Expressive writing
- Where
- 2 sites in Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Servicio Canario de Salud
Parkinson Disease, Motor Cortex
Effects of rTMS on Balance Performance and Functional Mobility in Parkinson's Disease
This study aimed to investigate the effects of rTMS on balance performance and functional mobility in people with PD. Additionally, it further examines the effects of single-session low-frequency and high-frequency repetitive…
- Conditions
- Parkinson Disease, Motor Cortex, Excitability, Balance
- Trial name
- NCT07195773
- Testing
- rTMS
- Where
- Taiwan
- Volunteers
- 21 people
- Sponsor
- Chung Shan Medical University
Autism
Therapeutic Intervention Effects of rTMS on Children With Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a common and complex neurodevelopmental disorder, which is characterized by impairments of social communication, social reciprocity, as well as restricted and repetitive behaviors (RRB).
- Trial name
- NCT05140356
- Testing
- Applied high amplitude repeated transcranial magnetic stimulation, Applied low amplitude repeated transcranial magnetic stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- University of Electronic Science and Technology of China
Healthy, Healthy Adult
Effects of Repetitive Transcranial Magnetic Stimulation on Two Cerebellar Targets
The purpose of this study is to understand how different areas of the cerebellum (a part of the brain) control different functions and how they can be influenced by non-invasive brain stimulation.
- Trial name
- StimCervelet (NCT07561229)
- Testing
- Active rTMS - Lobule VIII, Active rTMS - Crus I/II, Cognitive and Motor Assessment Battery
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Benign Essential Blepharospasm
rTMS and Botulinum Toxin in Benign Essential Blepharospasm
Benign essential blepharospasm (BEB) is a functionally disabling focal dystonia. Botulinum neurotoxin (BoNT) therapy is suboptimal in many BEB patients.
- Trial name
- NCT02370875
- Testing
- Magstim RapidStim2
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Mild Cognitive Impairment
Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Mild Cognitive Impairment
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of mild cognitive impairment (MCI) patients' cognitive function by altering the cortical…
- Trial name
- NCT03647345
- Testing
- High-frequency rTMS on left DLPFC+anodal tDCS on right DLPFC, High-frequency rTMS on left DLPFC+cathodal tDCS on right DLPFC
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Samsung Medical Center
Cancer Survivor, Invasive Breast Carcinoma
A Home-Based Walking Program and rTMS in Helping Breast Cancer Survivors Get More Physical Activity
This trial studies how well a home-based walking program, with or without repetitive transcranial magnetic stimulation, works in helping breast cancer survivors get more physical activity.
- Trial name
- NCT03789877
- Testing
- Physical Activity, Questionnaire Administration, Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Roswell Park Cancer Institute