Clinical trials: rTMS Stimulation
Stroke, Hemiplegia
Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) Over the Brain on the Neurotransmitter Binding
The purpose of this study is to determine whether repetitive transcranial magnetic stimulation (rTMS) over the brain can modulate the binding of neurotransmitter (GABA in this study) to its receptor using the special PET study.
- Trial name
- NCT01819675
- Testing
- Low frequency rTMS, High frequency rTMS
- Where
- South Korea
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Chronic Low Back Pain (CLBP)
Effects of Repetitive Transcranial Magnetic Stimulation on Pain Thresholds in Patients With Chronic Low Back Pain
Chronic low back pain (CLBP) is a common reason for which patients are treated with opioids. Because the misuse of prescription opioids has become a serious problem in the Uinted States, finding effective alternative…
- Trial name
- NCT03973788
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Schizophrenia
Repetitive Transcranial Magnetic Stimulation for First-episode Schizophrenia Patients
The aim of the study is to evaluate the effects of repetitive transcranial magnetic stimulation(rTMS)in the first-episode Schizophrenic patients: the clinical and MRI findings
- Trial name
- rTMSfMRI (NCT01370291)
- Testing
- active Risperidone and active rTMS
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Major Depressive Disorder
Using Electrophysiology to Index Non-invasive Brain Stimulation Effects on Reward System Functioning in Depression
Depression is a leading cause of morbidity and mortality, conferring substantial healthcare and societal costs. By studying methods to non-invasively target neural circuitry involved in reward responsivity, information generated…
- Trial name
- NCT05194098
- Testing
- TMS: single session intermittent theta burst stimulation (iTBS) to dorsomedial prefrontal target in individuals with major depressive disorder, via MagVenture MagPro R30 device / Cool-DB80 A/P coil
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- San Francisco Veterans Affairs Medical Center
Epilepsy
fMRI Guided TMS Enhancement of Associative Memory Networks
This is a randomized, single-blinded, controlled phase 1 study to demonstrate feasibility and explore the neurophysiologic and clinical effects of repetitive transcranial magnetic stimulation (TMS) interventions in epilepsy…
- Trial name
- NCT02749422
- Testing
- MagStim RapidStim2
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Schizophrenia
Effect of Repetitive Transcranial Magnetic Stimulation on Resting State Brain Activity in Schizophrenia
This study compares the efficacy of low and high frequency repetitive transcranial magnetic stimulation (rTMS) as a means of treating subjects with schizophrenia. Magnetic pulses delivered over the scalp cause brain activity.
- Trial name
- NCT01620086
- Testing
- Active Repetitive Transcranial Magnetic Stimulation 1 Hz, Active Repetitive Transcranial Magnetic Stimulation 10 Hz, Active control site Repetitive Transcranial Magnetic Stimulation at 1Hz
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Parkinson Disease
The Effect of Dual-site Repetitive Transcranial Magnetic Stimulation on Freezing of Gait in PD
This study is a double-blinded randomized study examining the effectiveness of the dual-site repetitive transcranial magnetic stimulation on Freezing of Gait (FOG) in patients with Parkinson's disease.
- Trial name
- NCT05925296
- Testing
- magnetic stimulation
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Dyspnea
Effect of Non-invasive Magnetic Stimulation of the Brain on Breathlessness in Healthy Individuals.
The purpose of this study is to see if the front part of the brain called the "Dorsolateral Prefrontal Cortex" (DLPFC) has a role in our ability to feel breathlessness.
- Trial name
- AHrTMS (NCT05623696)
- Testing
- rTMS-L-DLPFC, rTMS-R-DLPFC
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Non Fluent Aphasia in Subacute Stroke
Dual Hemisphere rTMS for Rehabilitation of Post Stroke Aphasia
To investigate the therapeutic effect of dual hemisphere repetitive transcranial magnetic stimulation (rTMS) on post-stroke non fluent aphasia.
- Trial name
- NCT01850836
- Testing
- repetitive transcranial magnetic stimulation
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Assiut University
Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea (IBS-D)
Efficacy of Repeated Transcranial Magnetic Stimulation Combined With a Live Probiotic Tablet (Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Tablets, Live) in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)
To evaluate the overall efficacy of repeated Transcranial Magnetic Stimulation(rTMS) combined with a Live Probiotic tablet (Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus cereus Tablets, Live) in…
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea (IBS-D), Repetitive Transcranial Magnetic Stimulation (rTMS), Probiotic
- Trial name
- NCT06960369
- Testing
- rTMS combined with Live Probiotic tablet
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Soochow University
Depression
An Evaluation of Safety and Feasibility Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Adolescents With Depression
The objective of this investigation is to examine the safety and feasibility of a series of repetitive transcranial magnetic stimulation (rTMS) treatments (10 Hertz [Hz]; Left Dorsolateral Prefrontal Cortex), with a Neuronetics…
- Trial name
- NCT00587639
- Testing
- rTMS Treatment
- Where
- 3 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Multiple Sclerosis
Repetitive Deep Transcranial Magnetic Stimulation in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic-inflammatory autoimmune central nervous system disorder and a leading cause of neurological disability in younger adults in Western countries.
- Trial name
- rTMS in MS (NCT01106365)
- Testing
- H-coil (Repetitive deep transcranial magnetic stimulation)
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Dystonia
Transcranial Magnetic Stimulation for Focal Hand Dystonia
Background: The brain has natural electrical rhythms of brain activities. These rhythms may be different in people with movement disorders, such as dystonia (involuntary muscle movement, cramps, or tremors).
- Trial name
- NCT01792336
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Sleep Disturbance, Interaction
Integration of Tai Chi and Repetitive Transcranial Magnetic Stimulation for Sleep Disturbance in Older Adults
This is a novel and the first study to investigate the impacts of the integrated treatment of Tai Chi (TC) and repetitive transcranial magnetic stimulation (rTMS) on sleep disturbances and the potential mechanisms of arousal…
- Trial name
- NCT06411509
- Testing
- TC plus active rTMS, TC-alone, Low intensity physical exercise
- Where
- Hong Kong
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Dystonia, Tremor
Repetitive Transcranial Magnetic Stimulation (rTMS) for Dystonia and Tremor
The study will include subjects diagnosed with Dystonic Tremor (DT), Essential Tremor (ET), and healthy controls in the age range of 21-80 years. Electroencephalography (EEG) will be used as the primary outcome measure.
- Trial name
- NCT04299087
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS), Control group
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Florida
Healthy Volunteers
Mechanism of Non-invasive Magnetic Stimulation
Background: Transcranial magnetic stimulation (TMS) is form of non-invasive brain stimulation. It is approved to treat depression. TMS may help decrease drug craving. It is important to understand how TMS affects the brain.
- Trial name
- NCT03394066
- Testing
- TMS (MagVenture MagPro 100 with MagOption)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Stroke, Motor Disorder
Effects of Brain Network by Simultaneous Dual-mode Stimulation in Subacute Stroke Patients
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of stroke patients' motor function by altering the cortical excitability.
- Trial name
- NCT03279640
- Testing
- rTMS on ipsilesional M1, tDCS on contralesional M1
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Cannabis Use, SCHIZOPHRENIA
Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia
The central hypothesis is this: Brain circuits most relevant to cannabis use in schizophrenia are distinct from pathways identified in healthy controls who use cannabis.
- Conditions
- Cannabis Use, SCHIZOPHRENIA, Psychosis, rTMS
- Trial name
- NCT07196462
- Testing
- 3 Minute iTBS to the L DLPFC, One-Minute, Personalized, DMN Targeted CTBS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Pain Relief
Repetitive Transcranial Magnetic Stimulation and the Development of Ongoing Muscle Pain
The main purpose of the study is to assess the mechanisms of repeated sessions of repetitive trancranial magnetic stimulation (rTMS) applied on left dorsolateral prefrontal cortex on the development of pain in a prolonged muscle…
- Trial name
- NCT03263884
- Testing
- Repetitive trancranial magnetic stimulation (rTMS) group
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Verticality Perception, Self-motion Perception
Altered Vestibular Perception and Transcranial Magnetic Stimulation
The long-term goal of this research is to advance our knowledge of how information from the labyrinth is brought to perception and how adaptation to vestibular imbalance influences motion sensation.
- Trial name
- NCT02184130
- Testing
- transcranial magnetic stimulation and motion stimuli
- Where
- Switzerland
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Zurich