Clinical trials: stroke
Neurosciences, MRI
OPTIMIZATION of ADVANCED MR SEQUENCES
This monocentric methodological study aims at optimizing advanced MR sequences for image quality (reduced artefacts, signal to noise ratio, acquisition time, stability of quantitative measurements) on a new MR unit dedicated to…
- Conditions
- Neurosciences, MRI, Brain Tumor, Mental Disorders
- Trial name
- OPT-IRM (NCT05618990)
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Stroke Sequelae, Movement Disorders
Programmed Flexor-extensor Alternating Electrical Acupiont Stimulation on Limb Functional Reconstruction After Stroke
The purpose of this study is to study the effect mechanism of programmed flexor-extensor alternating electrical acupiont stimulation on upper limb functional reconstruction after stroke.
- Trial name
- NCT05333497
- Testing
- the fourth programmed generation of low-frequency acupoint electric stimulation therapy instrument, the fourth generation of low-frequency acupoint electric stimulation therapy instrument
- Where
- China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Yang Liu
Cerebral Vascular Accident
New Protocols in the Treatment of Upper Limb Dysfunctions of Patients With Stroke.
The fundamental goals of early rehabilitation for patients with stroke are: optimizing motor function within each patient's prognostic potential, preventing the development of secondary conditions that impact life-long health…
- Trial name
- NCT01947413
- Testing
- intermittent theta burst stimulation, continuous theta burst stimulation
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Acquired Brain Injury, Traumatic Brain Injury
Using Virtual Technologies to Prevent Injuries in Adolescents With Acquired Brain Injury
The objective of this study is to identify home safety hazards for adolescents with acquired brain injury and to identify adaptations to the home healthcare virtual simulation training system (HH-VSTS) to improve the user…
- Conditions
- Acquired Brain Injury, Traumatic Brain Injury, Stroke
- Trial name
- NCT04768946
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Stroke Patients, Chronic Stroke Patients
The Effect of Task-oriented Training on Upper Extremity Motor Functions in Chronic Stroke Patients
The aim of our study was to investigate the effects of task-oriented training added to conventional rehabilitation on upper extremity muscle thickness and upper extremity motor functions.
- Trial name
- NCT06701370
- Testing
- Task Oriented Training, Conventional Rehabilitation, Upper arm ergometer
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Biruni University
Lipodystrophy
Intraoperative Fluid Management of Liposuction , Cardiometry Versus Rohrich Formula
The aim of the study is to compare the hemodynamic parameters of fluid resuscitation using Rohrich formula to cardiometry guided stroke volume variation in patients undergoing large volume liposuction surgery .
- Trial name
- NCT05402982
- Testing
- Electrical Cardiometry (EC) ICON, Rohrich formula
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ahmed Abdel Wahed Ali
Stable Angina, Unstable Angina
Serum Uric Acid Levels and Onset of Cardiovascular Diseases: a CALIBER Study
Serum uric acid level is a commonly measured biomarker. The association between serum uric acid level and the risk of developing cardiovascular diseases has been observed in some studies, while others showed controversial…
- Conditions
- Stable Angina, Unstable Angina, Myocardial Infarction, Unheralded Coronary Heart Disease Death
- Trial name
- NCT03425305
- Volunteers
- 180,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Hemiplegia, Cerebral Palsy
Bimanual Training in Children With Hemiplegia
A randomized control trial of bimanual training in children with hemiplegia. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement…
- Conditions
- Hemiplegia, Cerebral Palsy, Children
- Trial name
- HABIT (NCT01413594)
- Testing
- HABIT
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Post-stroke Depression
To Explore the Neural Processing Mechanism of Cerebellum Involved in Facial Expression Recognition Based on Transcranial Magnetic Stimulation
Experiment 1: Utilizing a transcranial magnetic stimulation-electroencephalography/functional near-infrared spectroscopy system, the investigators aim to determine whether transcranial magnetic stimulation of the cerebellum can…
- Trial name
- NCT06860451
- Testing
- TMS
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Ischemic Stroke
Safety, Tolerability and Pharmacokinetics of SP-8203
Phase I study in health volunteers to assess the safety, tolerability and pharmacokinetics of escalating single doses and multiple doses of SP-8203
- Trial name
- NCT01757795
- Testing
- SP-8203
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Functional Disability, Dementia
Aspirin in Reducing Events in the Elderly
ASPREE-XT is a post-treatment, longitudinal observational follow-up study of ASPREE participants [ASPREE Investigator Group, 2013; www.aspree.org; McNeil et al 2017].
- Conditions
- Functional Disability, Dementia, Heart Disease, Stroke
- Trial name
- ASPREE (NCT01038583)
- Testing
- 100 mg enteric-coated aspirin
- Where
- 47 sites in United States, Australia
- Volunteers
- 19,114 people, healthy volunteers welcome
- Sponsor
- Hennepin Healthcare Research Institute
Cerebrovascular Accident
Validity and Reliability of an Activity Monitor in Persons With a Cerebrovascular Accident
Background:Accelerometry has only recently been introduced in clinical stroke research. However, whether accelerometry is a valid and reliable tool in stroke needs to be established.
- Trial name
- NCT00849446
- Testing
- Activity monitor (SenseWear Pro armband)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University College of Antwerp
Stroke, Acute
Tele-Stroke: Prehospital Identification of Patients With Suspected Stroke Using Onsite Mobile Telemedicine - Feasibility
Observational Study to investigate the technical feasibility, implementation into current diagnostic and treatment pathways and the diagnostic accuracy of the remote patient assessment by using mobile telecommunication ahead of…
- Trial name
- Tele-Stroke (NCT03370094)
- Testing
- Audio-video-streaming of suspected stroke symptoms and signs
- Where
- Switzerland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Cardiovascular Diseases, Heart Diseases
The North Kynouria Project
The North Kynouria Project was initiated to study cardiovascular/stroke risk factors by employing mass screening and long-term surveillance of an adult population in the municipality of North Kynouria, in the county of Arcadia…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Cerebrovascular Disease, Coronary Disease
- Trial name
- NCT06115213
- Testing
- Patient counselling
- Where
- Greece
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ioannina
Ischemic Stroke
Curative Efficacy of Secondary Prevention for Patients With Ischemic Stroke Through Syndrome Differentiation of TCM
The purpose of this study is to assess the efficacy and safety of Naoxintong Capsule in the secondary prevention of ischemic stroke by the multi-center, randomized,double-blind，placebo-controlled trial design project.
- Trial name
- NCT02334969
- Testing
- Naoxintong Capsule
- Where
- 24 sites in China
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Xiaofei Yu
Stroke
Exploring the Effect of Interactive Board Game Health Education on Improving Stroke Knowledge and Health Literacy in Community-Dwelling Adults
The purpose of this study is to explore the effectiveness between interactive board game health education and conventional health education in improving community-dwelling adults' stroke knowledge and self-reported stroke health…
- Trial name
- NCT05110105
- Testing
- Interactive board game health education, Conventional health education
- Where
- Taiwan
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Non Fluent Aphasia in Subacute Stroke
Dual Hemisphere rTMS for Rehabilitation of Post Stroke Aphasia
To investigate the therapeutic effect of dual hemisphere repetitive transcranial magnetic stimulation (rTMS) on post-stroke non fluent aphasia.
- Trial name
- NCT01850836
- Testing
- repetitive transcranial magnetic stimulation
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Assiut University
Stroke, Peripheral Sensory Neuropathy
Robot-aided Proprioceptive Rehabilitation Training
This study investigates the effect of a robot-aided 2-day proprioceptive training of the wrist on the proprioceptive and motor function of the wrist/hand complex in patients with proprioceptive impairment.
- Trial name
- NCT02565407
- Testing
- Proprioceptive training, Usual care
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Stroke, Cognitive Decline
Biomarkers Related to PSCI: An fNIRS Study
This is an fNIRS study performed to identify biomarkers related to post-stroke cognitive impairment.
- Trial name
- NCT06703307
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dingqun Bai
Stroke, Muscle Spasticity
The Effectiveness of Early Botulinum Toxin A Injection for Lower Limbs Spasticity in Subacute Stroke Adults
Botulinum toxin A (BoNT-A) injections are widely used to treat spasticity after stroke. Although this treatment is effective on muscle tone improvement, its effect on gait and ability of daily living on early stage of stroke…
- Trial name
- NCT02505802
- Testing
- BoNT-A injection
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
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