Clinical trials: stroke
Stroke
A Longitudinal Study of Function and Participation in Patients With Stroke
A longitudinal study of function and participation in patients with stroke: An integrated brain imaging and biomechanical analysis
- Trial name
- NCT02377453
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Surgery, Cardiac Death
Endothelial Dysfunction and Non-cardiac Surgery
Endothelial dysfunction is a cardiovascular disease hallmark. After non-cardiac surgery, cardiovascular events correlate with surgical outcomes. Understanding the role of endothelial function in these events is crucial.
- Conditions
- Surgery, Cardiac Death, Stroke, Myocardial Injury
- Trial name
- NCT05778981
- Testing
- FMD - Troponin measurement
- Where
- Chile
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Chile
Stroke, Cerebrovascular Accident
Spinal Plasticity to Enhance Motor Retraining After Stroke
The objective of this project is to study the effects of an emerging noninvasive neuromodulation strategy in human stroke survivors with movement-related disability.
- Conditions
- Stroke, Cerebrovascular Accident, Hemiparesis
- Trial name
- NCT03645122
- Testing
- Paired corticospinal-motoneuronal stimulation (PCMS)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Diabetes
Sustainable Culturally Adapted Nutrition (SCAN) Program
The purpose of the study is to determine the impact of an enhanced, food incentive program [called the sustainable culturally adapted nutrition (SCAN) program], which is integrated with the Diabetes Prevention Program (DPP) and a…
- Trial name
- NCT07220057
- Testing
- Live instructional video sessions, Links to educational videos, Diabetes Prevention Program (DPP)
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke, Spasticity
Effects of Low-level Laser Therapy on Spasticity and Gait Parameters in Chronic Stroke Patients With Spastic Plantar Flexors
Stroke is one of the leading causes of long-term disability worldwide. Many patients who survive a stroke experience muscle stiffness (called spasticity), especially in the ankle and foot muscles, which makes walking difficult…
- Conditions
- Stroke, Spasticity, Plantar Flexors
- Trial name
- LLLT-STROKE (NCT07273591)
- Testing
- Low Level Laser Therapy, conventional physical therapy
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Montiha Azeem
Safety, Tolerability
A Phase 1 Study of Y-3 in US Healthy Volunteers.
The goal of this clinical trial is to assess the safety, tolerability, and pharmacokinetic profiles of Y-3 in healthy adult volunteers in the United States.
- Conditions
- Safety, Tolerability, Pharmacokinetic Study in Healthy Volunteers
- Trial name
- NCT06770491
- Testing
- Y-3 for injection
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Neurodawn Pharmaceutical Co., Ltd.
Simulation, Dizziness
Virtual Patient Education From Real Cases
Misdiagnosis of neurological conditions is common in healthcare settings, sometimes with devastating consequences. Most diagnostic errors result from failures in bedside diagnostic reasoning.
- Conditions
- Simulation, Dizziness, Vertigo, Stroke
- Trial name
- ViPER (NCT04553640)
- Testing
- Group A/Intervention Curriculum, Group B/Control Curriculum
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
CVA (Cerebrovascular Accident)
Incline Training to Personalize Motor Control Interventions After Stroke
This study will evaluate the use of incline and decline treadmill training to address specific motor control deficits identified within different post-stroke walking patterns.
- Trial name
- NCT03561246
- Testing
- Incline treadmill walking, Decline treadmill walking, Level Treadmill (Control)
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Spatial Neglect, Stroke
Transcranial Stimulation (tDCS) and Prism Adaptation in Spatial Neglect Rehabilitation
The present study aims to compare the relative therapeutic efficacy of prism adaptation therapy combined with real versus sham tDCS.
- Conditions
- Spatial Neglect, Stroke, Cerebrovascular Disorders, Cerebral Infarction
- Trial name
- NCT02080286
- Testing
- Prism Adaptation, Anodal tDCS
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Stroke
Genetic and Environmental Risk Factors for Hemorrhagic Stroke-GERFHS III
The purpose of this study is to find risk factors for hemorrhagic stroke, specifically intracerebral hemorrhage (ICH). ICH, a type of bleeding into brain tissue, is a type of stroke that can result in death or disability in a…
- Trial name
- GERFHS-III (NCT00930280)
- Where
- United States
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Stroke
The Effects of Whole Body Vibration in People With Chronic Stroke
Whole body vibration (WBV) has been found to be useful in promoting bone health and muscle performance in older adults. To date, no study has examined the effects of different WBV frequencies on the properties of the muscle-bone…
- Trial name
- NCT03982251
- Testing
- High frequency whole body vibration, Low frequency whole body vibration
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Stroke
Fast Stepping in Stroke Patients for Fall Prediction and Prevention:Control Mechanisms and Clinical Implications
The purpose of this study was to compare the balance strategy, as well as center of pressure (COP) trajectory and parameters between healthy adults and patients with hemiplegia in response to slow- and fast-speed waist- pulling…
- Trial name
- NCT00167037
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke
Non-Invasive Brain Stimulation
The study focusses on utilizing neuroimaging modalities, including Electroencephalography (EEG) and Functional Magnetic Resonance Imaging (fMRI) to study the impact of non-invasive brain stimulation on the prefrontal cortex…
- Trial name
- NCT04318522
- Testing
- Transcranial Direct Current Stimulator
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Poststroke/CVA Hemiparesis, Paralytic Stroke
BCI Post-stroke Neurorehabilitation
The goal is to evaluate the potential of a EEG based BCI (Brain-Computer-Interface) connected to a non-invasive pneumatic glove for rehabilitation of hand-movements post-stroke.
- Conditions
- Poststroke/CVA Hemiparesis, Paralytic Stroke, Hand Flaccid Paralysis
- Trial name
- BCI-stroke (NCT02404857)
- Testing
- EEG based Brain Computer Interface
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Dysphagia, Oropharyngeal, Stroke
Screening of Dysphagia Via Ultrasonography in Patients With Stroke
Oropharyngeal dysphagia is commonly seen in patients with stroke. Clinical assessment may be used to evaluate dysphagia in patients with stroke however reliability of this method is controversial and videofluoroscopic study is…
- Trial name
- NCT04344392
- Testing
- Ultrasonographic study, Videofluoroscopic study temporal parameters, Videofluoroscopic study distance parameters
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Stroke
Importance of Core Stability for Coordinated Movement of the Human Body in Stroke Rehabilitation
This is an observational study. Measurements were made during two different motor tasks: trunk tilts without and with the tension of the abdominal muscles in the sitting position and walking in a place with high knee lifting.
- Trial name
- NCT04886466
- Testing
- core stability in a sitting position and while walking in one place
- Where
- Poland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Anna Olczak
Type 2 Diabetes, Coronary Heart Disease
NMR Metabolomics-Based Risk Assessment and Stratified Digital Health Interventions in Middle-Aged Adults (PREMAP)
PREMAP invites residents of the Eloisa region (South Savo, Finland) turning 45, 50, or 55 years of age in 2026 to undergo a blood-based NMR metabolomics risk assessment for five interlinked cardio-renal-metabolic conditions (type…
- Conditions
- Type 2 Diabetes, Coronary Heart Disease, Myocardial Infarction, Cerebrovascular Disease
- Trial name
- PREMAP (NCT07820800)
- Testing
- Digital health interventions
- Where
- Finland
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Post-stroke Depression
SCED - Wisdom Enhancement for Post-Stroke Depression
One-third of stroke survivors experience post-stroke depression, but there are currently no official guidelines for supporting them.
- Trial name
- WE-PSD (NCT06451965)
- Testing
- Timeline Intervention
- Where
- United Kingdom
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Chronic Stroke Patient, Motor Impairment
Multifocal Theta-Burst Stimulation to Enhance Upper Limb Motor Recovery After Stroke (INSPIRE)
Stroke is one of the leading causes of long-term disability worldwide. Many individuals who survive a stroke continue to experience weakness and reduced control of one arm, even months or years after the event.
- Conditions
- Chronic Stroke Patient, Motor Impairment, Neurorehabilitation, Theta Burst Stimulation
- Trial name
- INSPIRE (NCT07439367)
- Testing
- Active iTBS, Tablet-based upper limb training
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva
Deglutition Disorders, Dysphagia
Development of a Web-Based Course to Maintain Skills in Nurses Trained to Screen for Dysphagia
This research aims to facilitate the successful implementation of the new Heart and Stroke Foundation of Ontario dysphagia screening model for acute stroke patients.
- Conditions
- Deglutition Disorders, Dysphagia, Stroke
- Trial name
- NCT00570557
- Testing
- TOR-BSST© Refresher Training
- Where
- 5 sites in United States, Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
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