Clinical trials: stroke
Subacute Stroke
Rehabilitation Robotics After a Stroke
Upper limb motor control after a stroke may be improved with rehabilitation robotics at a subacute stage. The aim of this multicenter controled randomized single blind study is to define the place of rehabilitation robotics at…
- Trial name
- REM_AVC (NCT01383512)
- Testing
- ARMEO Spring, Self rehabilitation
- Where
- 23 sites in France
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Stroke
Influences of Cane Use on Voluntary Forward Stepping Movement and Associated Attentional Demands in Hemiplegic Patients
The purpose of this study was to examine the influence of cane use on the movement, kinetics, and associated attentional demands of performing a voluntary forward stepping movement in patients with stroke and age-matched healthy…
- Trial name
- NCT00172146
- Where
- Taiwan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke
SMARTCap Stroke Study: A Field Deployable Blood Test for Stroke
The hypothesis is that a stroke causes release of purines from brain into blood and that this is a very early biomarker of brain ischaemia.
- Trial name
- SMARTCAP (NCT02308605)
- Testing
- SMARTCap
- Where
- 2 sites in United Kingdom
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Carotid Artery Diseases, Carotid Artery Plaque
The Carotid Artery Multi-modality Imaging Prognostic (CAMP) Study
Carotid artery disease is a main cause of ischemic stroke and vascular dementia, and a highly prevalent disease. There is uncertainty about the optimal management of patients with serendipitously or systematically detected…
- Conditions
- Carotid Artery Diseases, Carotid Artery Plaque, Carotid Atherosclerosis
- Trial name
- NCT04679727
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Stroke, Problem of Aging
Modulation of Cerebral Blood Flow Using Iron Chelators
The purpose of this study is determine if the iron chelator, desferrioxamine can increase blood levels of hypoxia-inducible transcription factor 1 (HIF-1 protein) and to see if there is a corresponding increase in blood flow to…
- Trial name
- DFO (NCT01365104)
- Testing
- desferrioxamine
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Stroke
User Requirements of the Neurorehabilitation Ecosystem for Sustained Therapy
In this study the user requirements of the Neurorehabilitation Ecosystem for Sustained Treatment (NEST), a system containing: an exercise app, smartwatch and virtual coach designed for stroke survivors, will be investigated.
- Trial name
- NEST (NCT07572487)
- Where
- 3 sites in Italy, Netherlands and 1 more
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sint Maartenskliniek
Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke
RCT of HeartBot in Women
The goal of this clinical trial is to find out whether an app-based program called HeartBot II, which uses an artificial intelligence (AI) chatbot, can help improve women's awareness and knowledge of heart attacks in women.
- Conditions
- Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke, Participants Should Have no Terminal Illness or Diagnosed Cognitive Impairment, Including Alzheimer's Disease, Participants Should Not be a Healthcare Professionals or Healthcare Trainees
- Trial name
- HeartBot II (NCT07416734)
- Testing
- HeartBot II Program, Waitlist Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stroke, Ischemic, Stroke Syndrome
CUHK Brain Health Longitudinal Study
The goal of this study is to develop a large longitudinal cohort of individuals diagnosed with or at high risk for brain diseases (both neurological and psychiatric in nature), in order to identify risk factors that contribute to…
- Conditions
- Stroke, Ischemic, Stroke Syndrome, Stroke, Stroke, Acute
- Trial name
- BHS (NCT03592563)
- Testing
- Neuro-QoL questionnaire
- Where
- 2 sites in Hong Kong
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Stroke, Caregiving Burden
CaknaStrok Education Package for Stroke Caregivers
This study evaluated the feasibility and potential effectiveness of the CaknaStrok Education Package (CEP), a culturally tailored education package developed to support informal caregivers of stroke survivors.
- Conditions
- Stroke, Caregiving Burden, Caregiver, Caregiver Burden for Those Who Care for Adults With Impaired Functional Status
- Trial name
- CaknaStrok (NCT07807332)
- Testing
- CaknaStrok Education Package (CEP)
- Where
- Malaysia
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Clinical Research Centre, Malaysia
Stroke Sequelae, Gait, Hemiplegic
ACTive Exoskeleton for Unilaterally-Assisted Locomotion (ACTUAL)
Walking difficulties are common symptoms after stroke, significantly reducing quality of life. Walking recovery is therefore one of the main priorities of rehabilitation.
- Trial name
- ACTUAL (NCT06061601)
- Testing
- Exoskeleton stroke group
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke, Aphasia
Language Processing and TMS
This study will examine the effect of TMS on people with stroke and aphasia as well as healthy individuals.
- Conditions
- Stroke, Aphasia, Language
- Trial name
- NCT05425615
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Acute Ischemic Stroke
Buyang Huanwu Decoction With Wuling Powder for Acute Ischemic Stroke
Acute ischemic stroke is a common cause of disability. Standard Western medical treatment is widely used, but some patients continue to have neurological impairment and difficulty with daily activities after stroke.
- Trial name
- BYHW-WL (NCT07687043)
- Testing
- Standard Western Medical Treatment, Serum Sample Collection for Metabolomics Only, Buyang Huanwu Decoction Combined With Wuling Powder
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Liaoning University of Traditional Chinese Medicine
Central Apnoeas, Stroke Patients
Pathophysiology of Central Apnoeas in Stroke Patients
40% of patients with Sleep Disorder Breathing (SDB) appearing during the acute phase of stroke show a respiratory pattern characterized by central apnoeas and/or periodic breathing.
- Trial name
- NCT01723189
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MPons
Stroke-induced Aphasia
Overcoming Learned Non-Use in Chronic Aphasia
In this study the investigators are examining the effectiveness of intensive speech therapy in chronic moderate-to-severe stroke-induced aphasia under two conditions - responses "constrained" or unconstrained to speech.
- Trial name
- NCT02012374
- Testing
- Intensive Language Action Therapy
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Stroke
The Effect of Transitional Care Model-Based Interventions for Stroke Patients and Their Caregivers
Stroke affects both the patient's and the caregiver's whole life by creating permanent damages. Patients and their families need further information and support in the transition from hospital to home.
- Trial name
- TEMpEST (NCT03708835)
- Testing
- Transitional care model
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- The Scientific and Technological Research Council of Turkey
Neurologic Disorder, Parkinson Disease
High Intensity Functional Training for Individuals With Neurologic Diagnoses and Their Care Partners
Individuals with and without neurologic diagnoses greatly benefit from participation in regular exercise but the majority are physically inactive.
- Conditions
- Neurologic Disorder, Parkinson Disease, Spinal Cord Injuries, Spina Bifida
- Trial name
- SHIFT-AR (NCT05951985)
- Testing
- HIFT
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Cerebral Infarction
A Spinal Functional Magnetic Resonance Imagine (fMRI) Study of Resting-State, Motor Task and Acupoint Stimulation
The spinal cord is a very important part of the central nervous system. fMRI can be applied to observe functional status of the human spinal cord.
- Trial name
- NCT00629655
- Testing
- motor task, sensory stimulation
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- China Rehabilitation Research Center
Stable Angina, Myocardial Infarction
Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease
The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study.
- Conditions
- Stable Angina, Myocardial Infarction, Coronary Heart Disease, Heart Failure
- Trial name
- NCT02244853
- Where
- United Kingdom
- Volunteers
- 51,703 people, healthy volunteers welcome
- Sponsor
- University College, London
Cardiovascular Disease, Diabetes
Meta-Analyses of Low-risk Lifestyle Behaviours and Patient Important Outcomes
Public health policy is universal in recommending the adoption of low risk low-risk lifestyle behaviors for health promotion and prevention of chronic or non-communicable diseases (NCDs).These behaviors generally include…
- Conditions
- Cardiovascular Disease, Diabetes, Cancer, Mortality
- Trial name
- NCT03234101
- Testing
- Low-risk lifestyle behaviours
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Stroke, Ischemic
Using SystemCHANGE™ to Enhance Medication Adherence in Older Adult Stroke Survivors
This study evaluated the feasibility and acceptability of using a SystemCHANGE intervention in older adult stroke survivors to improve medication adherence.
- Trial name
- NCT03211130
- Testing
- SystemCHANGE™, Attention-Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
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