Clinical trials: stroke
Cerebral Stroke, Diabetes Mellitus
MRI Study of the Structural and Functional Rehabilitation in the Cerebral Infarction Patients With Diabetes
Diabetes mellitus (DM) plays an important role in the occurrence of the cerebral infarction (CI). Clinical studies have demonstrated that the CI patients with DM had a poor prognosis compared with those without DM.
- Trial name
- NCT02540733
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Stroke
Correlation Analysis Between Brain Lesions and Sensorimotor Impairments in Individuals With Stroke (Preliminary Study)
The objective of the preliminary study is: 1. To identify correlations between brain lesions and sensorimotor impairments in stroke. 2.
- Trial name
- NCT02465281
- Testing
- Device: 3T scanner with MRI-compatible robot
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Post-stroke Dementia, Vascular Mild Cognitive Impairment
The Influence of Sequential Tau Protein and Amyloid Plaque Imaging Changes on Stroke Prognosis and Cognitive Outcome
Amyloid plaques and tau protein are the landmarks of neurodegeneration in Alzheimer's disease (AD). On the other hand, it is reported that cerebral ischemia may induce amyloid plaques and tau protein accumulation.
- Trial name
- NCT04572477
- Testing
- [18F]THK-5351, [18F]AV-45
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Ischemic Stroke
Stepper Aerobic Training on Fitness, Disability, Inflammation and Thrombosis in Stroke Patients
Stroke rehabilitation of hemiplegics primarily lies in motor control and training of activities of daily life. Whole body aerobics is much less emphasized.
- Trial name
- NCT02923765
- Testing
- Aerobic training by a stepper
- Where
- Taiwan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Healthy
Neuromodulation and Language Acquisition (Stage Ib)
The purpose of this study is to determine whether rivastigmine or pramipexol are effective in boosting semantic language acquisition in healthy subjects.
- Trial name
- NCT00102856
- Testing
- Pramipexole, Rivastigmine
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Stroke, Transcranial Direct Current Stimulation
Hemodynamic Response of Anodal Transcranial Direct Current Stimulation Over the Cerebellar Hemisphere in Healthy Subjects
Upper extremity motor impairment is one of the major sequelae of stroke, resulting in limitation of activities of daily livings.
- Conditions
- Stroke, Transcranial Direct Current Stimulation, Functional Near Infrared Spectroscopy
- Trial name
- NCT04101695
- Testing
- tDCS
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Perinatal Arterial Ischemic Stroke, Neonatal Stroke
Perinatal Arterial Stroke Treated With Stromal Cells Intranasally
This study will assess safety and feasibility of bone marrow-derived allogeneic MSCs, administered by the nasal route, in neonates who suffered from PAIS.
- Trial name
- PASSIoN (NCT03356821)
- Testing
- Mesenchymal Stem Cells
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Stroke
Piloting GETCare: A Remote Goal-based Education and Skills Training Program for Caregivers Poststroke
The purpose of this study was to evaluate the GETCare program, a Goal-based Education and skills Training program for Caregivers poststroke.
- Trial name
- GETCare (NCT05403021)
- Testing
- GETCare Intervention
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Utah
Cerebrovascular Disorders
Identification of microRNAs Involved in Cerebral Collateral Regulation
Patients >18 years of age presenting to Ohio State Wexner Medical Center Emergency department with stroke symptoms, within 6 hours of last know well and found to have acute anterior circulation large vessel occlusion (LVO) will…
- Trial name
- microRNA (NCT03905434)
- Testing
- miRNA sampling
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Cerebral Infarction
The Effect of Erigeron Injection on Acute Cerebral Infarction Serum VEGF, MMP-9 and EPC Levels
To study the effects of Erigeron Injection on human serum VEGF, MMP-9 and EPC levels after acute cerebral infarction,test is made by random double-blind controlled.patients with acute cerebral infarction were divided randomly…
- Trial name
- NCT01926834
- Testing
- Erigeron Injection
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Hemiparesis;Poststroke/CVA
Strengthening in Sub-acute Stroke Survivors: A Randomized Controlled Trial
The goal of this study is to compare between Eccentric training and conventional therapy in sub-acute stroke survivors. The primary objective of this study is to evaluate improvements in gait speed after four months of ET in…
- Trial name
- NCT06140381
- Testing
- Eccentric training, Conventional therapy
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clinique Du Parc de Belleville
Healthy
Rowing Biomechanics - Effects of (In)Stability and Fatigue
Rowing simulators are frequently used by rowers, when on-water training is impossible or limited. While such devices are highly valuable to maintain rowers' fitness, a concern was raised about extensive simulator usage.
- Trial name
- RowBio (NCT03253900)
- Testing
- Stable rowing simulator, Slides based rowing simulator, Tilt board based rowing simulator
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Pelvic Floor Muscle Weakness, Stroke
Multimodal Pelvic Floor Rehabilitation in Chronic Stroke Survivors: Long-Term Efficacy, Optimal Protocols, and Adjunctive Therapies for Comprehensive Pelvic Floor Dysfunction.
Evaluate long-term efficacy of multimodal PFMT in chronic stroke survivors with PFD.
- Trial name
- RCT (NCT07420569)
- Testing
- Core PFMT: 8-12 contractions (6-10s hold), 3 sets/day, progressed over 16 weeks. • Group A (Standard PFMT): 3 supervised/week (weeks 1-8), 1/week (9-16) + home. • Group B (Intensified PFMT): 5/week, Core PFMT: 8-12 contractions (6-10s hold), 3 sets/day, progressed over 16 weeks.
- Where
- Uganda
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Iqra National University
Stroke
Thrombolytic Care During Inter-hospital Transfer
Evaluation of ischemic stroke patients receiving tissue plasminogen activator (rtPA) during air ambulance transfer
- Trial name
- NCT02752256
- Testing
- Tissue Plasminogen Activator
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Stroke
Effectiveness of Perturbations Exercises in Improving Balance, Function and Mobility in Stroke Patients
Following stroke, patients loses functions of the motor, sensory and higher brain cognitive faculties to various degrees which lead to diminished balance.
- Trial name
- perturbation (NCT03234426)
- Testing
- Perturbation, Conventional Physiotherapy Treatment
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mahatma Gandhi Institute of Medical Sciences
Stroke Volume, Cardiovascular System
Passive Leg Raise Induced Stroke Volume Changes in Elderly Prior to Elective Surgery Measured by LiDCOplusTM
This is a pilot study to investigate whether patients at advanced age are fluid responders via a reversible fluid challenge, the passive leg raise test.
- Conditions
- Stroke Volume, Cardiovascular System, Fluid Therapy
- Trial name
- NCT02977390
- Testing
- Passive leg raise
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Stroke
First in Human Clinical Trial of ApTOLL in Healthy Volunteers
This is a Phase I, first-in-human, dose ascending, randomized, placebo-controlled clinical study to assess the tolerability and pharmacokinetics of ApTOLL in healthy volunteers.
- Trial name
- NCT04742062
- Testing
- ApTOLL
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- aptaTargets S.L.
Ischemic Stroke
Microclots and Neutrophil Activation as Potential Indicators for Stroke Risk and Reperfusion Failure
Stroke remains a major health burden worldwide. Many patients are severely disabled and stay in need of care. Mechanical thrombectomy has dramatically improved outcomes for stroke patients with large vessel occlusions, yet 40-50%…
- Trial name
- CLOTSAFE (NCT06530927)
- Testing
- 3D rotational digital tomography, Atomic Force Microscopy, Micro-Computertomography
- Where
- Switzerland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Stroke
Turning Performance in Stroke
Turning is a challenging task for stroke patient. Previous studies showed that turning is one of the activities which resulting in falling frequently in stroke.
- Trial name
- NCT05020886
- Testing
- turning task
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Aphasia
Effect of Communication Partner Training Program for the Management of Persons With Aphasia
Communication Partner Training (CPT) is an evidence-based intervention that teaches communication partners (e.g., family members, friends, healthcare workers) how to best support conversation and interaction for a person with…
- Trial name
- NCT05225922
- Testing
- Communication Partner Training, Usual Speech and language Therapy
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Riphah International University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.