Clinical trials: stroke
Stroke
The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Non-stroke Volunteers
This randomized controlled trial investigates the effect of a single dose of glucagon-like peptide-1 (GLP-1) receptor agonist on cerebral blood flow velocity and cortical oxygination in humans without cerebrovascular disease.
- Trial name
- EGRABINS1 (NCT02838589)
- Testing
- Byetta, Isotonic saline
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Christina Kruuse
Stroke
Efficacy of an Interactive Web-Based Home Therapy Program After Stroke
This is an online study that involves assessment and training of arm function at home. Stroke is the leading cause of disability worldwide.
- Trial name
- STRONG (NCT03484182)
- Testing
- Web-based Home Exercise Program, Standard Home Exercise Program
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Diabetes Mellitus, Type 2 Diabetes
The Hong Kong Diabetes Biobank
Asia is in the midst of an epidemic of diabetes. Epidemiological figures suggest that there are more than 110 million people affected by diabetes in China, with a significant proportion of young adults already affected.
- Conditions
- Diabetes Mellitus, Type 2 Diabetes, Type 1 Diabetes, Diabetic Nephropathies
- Trial name
- HKDB (NCT05282680)
- Testing
- prospective observational study
- Where
- Hong Kong
- Volunteers
- 48,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Acute Ischemic Stroke
Prospective Registry for Assessment of Acute Ischemic Stroke Patients Treated With Neurothrombectomy Devices in India
PRAAN is a post-market registry designed to collect real-world data associated with the use of Medtronic market release neurothrombectomy devices in acute ischemic stroke (AIS) patients from India.
- Trial name
- PRAAN (NCT05005962)
- Testing
- Neurothrombectomy
- Where
- 14 sites in India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Cardiovascular Diseases, Fatty Liver
Ultrasound Assessment of Atherosclerotic Plaque Burden and Cardiovascular Risk: A 10-Year Prospective Study
The P-SONAR study is a large, observational, prospective cohort study. The overall aim of the study is to investigate whether plaque burden estimation by 2D ultrasound of the carotid and femoral arteries may enhance…
- Conditions
- Cardiovascular Diseases, Fatty Liver, Atherosclerosis of Femoral Artery, Carotid Artery Plaque
- Trial name
- P-SONAR (NCT06933745)
- Where
- Norway
- Volunteers
- 21,029 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Healthy
GLP-1's Effect on Cardiac Parameters and Mesenteric Blood Flow
to investigate the effect of the human incretin hormone GLP-1 on mesenteric blood flow and cardiac parameters
- Trial name
- NCT01988545
- Testing
- 1,5 nmol/kg,GLP-1 sc injection, 1,5 nmol/kg GLP-1 9-36amide, sc injection, Exendin-4 ;10 ug,sc injection
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Stroke
Assessment of Robotic Assistance on Gait Parameters Among Healthy Subjects and Brain Damaged Patients
The main objective of this study is to quantitatively assess the robotic assistance given by an exoskeleton on patients gait parameters. Patients will be asked to walk with- and without the exoskeleton on a treadmill.
- Trial name
- MARAT (NCT05264103)
- Testing
- Exoskeleton for gait rehabilitation (Atalante)
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Stroke
Muscle Oxygenation in Stroke Patients
In addition to its many effects, physical movement is known to change both systemic blood circulation and muscle blood flow. In a study examining the effects of motor imagery, which produces effects similar to physical movement…
- Trial name
- NCT06106542
- Testing
- assessment
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Annexin A2, Stroke
Genetic Variants of Annexin A2 and Cryptogenic Stroke
Stroke is the third most common cause of death in developed countries. Various mechanisms of ischemic stroke exist. However, in young population, in a third of cases, the cause of a stroke cannot be determined despite an…
- Conditions
- Annexin A2, Stroke, Genetic Variants of Host, Fibrinolysis
- Trial name
- GENANXVA (NCT06880107)
- Testing
- blood withdrawal
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Acute Coronary Syndrome, Stroke
Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SP-8008
This is a single-centre, double-blind, randomised, placebo-controlled single oral-dose escalation study in healthy male subjects. It is planned to enrol approximately 48 subjects into up to 6 planned dose level cohorts.
- Trial name
- NCT04770194
- Testing
- SP-8008 Prototype Capsule A, SP-8008 Prototype Capsule B
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Stroke, Ischemic Stroke
Salicornia for Neurovascular Health Improve
The purpose of this study is evaluate the effect and safety of the administration of a food supplement based on halophyte plant extracts versus placebo in the neurovascular healthy.
- Conditions
- Stroke, Ischemic Stroke, Neurovascular Injury, Brain Ischemia
- Trial name
- NCT06076122
- Testing
- Food supplement based on Salicornia extracts
- Where
- Spain
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Acquired Brain Injury (Including Stroke), Caregivers
Nature in Harmony: Music and Nature-based Self-care for Individuals With Acquired Brain Injuries and Their Care Partners
The goal of this pilot study is to determine the initial impact on wellbeing for clients with acquired brain injury and their care partner after engaging in a nature \& music-based program facilitated by occupational therapy and…
- Trial name
- NCT07568301
- Testing
- Nature in Harmony
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Stroke
Influence of Assistive Device Use While Performing Dual Task in Patients With Stroke
The primary purposes of the this three-year research proposal are to investigate the influence of assistive device use on dynamic balance and the associated attentional demands during standing and walking in patients with stroke
- Trial name
- NCT00173719
- Testing
- Standard cane
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Atrial Fibrillation, Stroke
Systematic ECG Screening for Atrial Fibrillation Among 75 Year Old Subjects in the Region of Stockholm and Halland, Sweden
The purpose of this study is to determine whether screening for atrial fibrillation by intermittent ECG recording and initiation of anticoagulation treatment among high risk individuals is cost-effective and can lower the…
- Trial name
- NCT01593553
- Testing
- ECG screening for atrial fibrillation using intermittent ECG recorder
- Where
- Sweden
- Volunteers
- 7,173 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Stroke, Deficit in Manual Activities
Improving Bi-manual Activities in Stroke Patients With Application of Neuro-stimulation
Noninvasive brain stimulations (NIBS) will be used in healthy volunteers and in chronic stroke patients to improve bimanual activities and motor learning.
- Trial name
- NCT02308852
- Testing
- tDCS
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Traumatic Brain Injury, Stroke
Remote Neuropsychological Assessment of Patients With Neurological Disorders and Injuries
For the last decades, many aspects of human life have been altered by digital technology. For health care, this have opened a possibility for patients who have difficulties travelling a long distance to a hospital to meet with…
- Conditions
- Traumatic Brain Injury, Stroke, Multiple Sclerosis, Parkinson Disease
- Trial name
- NCT05819008
- Testing
- Neuropsychological Assessment
- Where
- Sweden
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Umeå University
Oropharyngeal Dysphagia, Stroke
The Utility of Cerebellar Transcranial Magnetic Stimulation in the Neurorehabilitation of Dysphagia After Stroke
The study is designed to explore the effectiveness of non-invasive cerebellar stimulation to enhance motor plasticity in the cortex after stroke.
- Trial name
- NCT03274947
- Testing
- Cerebellar TMS
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Heat Stroke
Study of Thermoregulation in Exercise Heat Stroke in the Military Environment
The EXPLO-MITO study is an ancillary study from the main EXPLO-CCE study (NCT04593316; IDRCB: 2020-A01967-32). The Heat Tolerance Test (HTT) is a physiological exploration that has several advantages for use in research and…
- Trial name
- EXPLO-MITO (NCT05847465)
- Testing
- Bike stress test, Heat Tolerance Test, Heat nociception test
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Acute Ischemic Stroke
The Effect and Mechanism of wCST-LL Based Precision Rehabilitation Nursing on Motor Dysfunction After Acute Stroke
Ischemic stroke is the main cause of disability in the world. More than 70% of stroke patients show various degrees of neural function impairment.
- Trial name
- NCT03702452
- Testing
- functional rehabilitation nursing program, control group
- Where
- China
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intracranial Aneurysm, Subarachnoid Hemorrhage
Familial Intracranial Aneurysm Study II
The purposes of this study are to identify possible genes that may increase the risk of aneurysm development in the brain, and to determine the effect of environmental factors such as cigarette smoking and high blood pressure on…
- Trial name
- NCT00071565
- Where
- 16 sites in United States
- Volunteers
- 5,875 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
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