Clinical trials: stroke
Stroke
The Effect of rPMS on Motor Skill Performance in Persons With a Stroke.
In the past two decades, even as stroke cases increase around the world, advances in motor rehabilitation have been limited. Clinical trials of stroke rehabilitation have examined the therapeutic utility of several…
- Trial name
- NCT05833490
- Testing
- Repetitive Peripheral Magnetic Stimulation (rPMS)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Stroke
Neurofeedback for Upper-limb Recovery After Stroke
Interventional study with minimal risks and constraints, prospective, monocentric.
- Trial name
- NeuroFB-AVC (NCT03766113)
- Testing
- Neurofeedback coupling electroencephalogram and functional MRI in time actual, Electroencephalogram-neurofeedback program or Neurofeedback-free mental imaging program with electroencephalogram recording, Neurofeedback coupling electroencephalogram and functional MRI in time actual or a neurofeedback-free mental imaging program with electroencephalogram recording
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Safety, Tolerability
A Phase 1 Study of Y-3 in US Healthy Volunteers.
The goal of this clinical trial is to assess the safety, tolerability, and pharmacokinetic profiles of Y-3 in healthy adult volunteers in the United States.
- Conditions
- Safety, Tolerability, Pharmacokinetic Study in Healthy Volunteers
- Trial name
- NCT06770491
- Testing
- Y-3 for injection
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Neurodawn Pharmaceutical Co., Ltd.
Stroke, Ischemic, Stroke Hemorrhagic
Identification of Biomarkers in Ischemic Stroke - Clinical Trial
The objective of the study is to determine RNA blood biomarker based on 9 genes already identified in experimental studies, whose expression would be significantly increased in patient with ischemic stroke compared to controls.
- Trial name
- IBIS-CT (NCT04253275)
- Testing
- blood samples, MRI without injection
- Where
- France
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Abdominal Aortic Aneurysm, Coronary Heart Disease NOS
Social Deprivation and Initial Presentation of 12 Cardiovascular Diseases: a CALIBER Study
Study of heterogeneity in associations between social deprivation and the initial presentation of 12 cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease NOS, Unheralded Corronary Death, Intracerebral Haemorrhage
- Trial name
- IP4 (NCT01937065)
- Testing
- No treatment
- Where
- United Kingdom
- Volunteers
- 1,937,360 people, healthy volunteers welcome
- Sponsor
- University College, London
Gait Re-training in Healthy Subjects, Gait Re-training in Stroke Survivors
Pelvic Obliquity Rehabilitation in Stroke Patients Using Robotically Generated Force Fields
To test the usability and effectiveness of a robotic device, called the Robotic Gait Rehabilitation (RGR) Trainer, in (1) healthy subjects with no gait impairment and (2) patients with stroke with gait abnormalities secondary to…
- Trial name
- NCT01684267
- Testing
- Robotic Gait Rehabilitation (RGR) Trainer
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Stroke, Parkinson Disease
Exploratory Study About the Implementation of Technology in the Rehabilitation
This qualitative study aims to identify the needs and recommendations of both patients and healthcare professionals in terms of rehabilitation technology, more specific three pre-defined user scenarios.
- Conditions
- Stroke, Parkinson Disease, Covid19, Neglect, Hemispatial
- Trial name
- NCT04833088
- Testing
- Focus group discussions
- Where
- Belgium
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Spasticity, Multiple Sclerosis, Stroke, Trauma
Antispastic Effect of Transcranial Magnetic Stimulation in Patients With Cerebral and Spinal Spasticity
Spasticity - movement disorder, which is part of the syndrome of defeat top motor-neuron, characterized by the rate-dependent increase in muscle tone and increased dry-core reflections from hyperexcitability of stretch receptors…
- Trial name
- ANTMS (NCT01786005)
- Testing
- Transcranial magnetic stimulation
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Russian Academy of Medical Sciences
Blindness, Cerebrovascular Accident
Mechanisms of Human Plasticity in the Human System
The purpose of this study is to investigate the physiology associated with plasticity of the motor system. Plasticity refers to the process by which neighboring brain cells assume the responsibilities of damaged or diseased brain…
- Conditions
- Blindness, Cerebrovascular Accident, Spinal Cord Injury
- Trial name
- NCT00001661
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Assistance Delivery and Muscle Coordination
The experiment will be conducted with 15 chronic stroke survivors and 15 control subjects. Subjects will perform extension movements of the index finger of their more-impaired (stroke) or nondominant (control) hand under two…
- Trial name
- NCT07011173
- Testing
- Exotendon assistance, End-effector assistance
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Catholic University of America
Post-stroke Gait Assessments
Supraspinal Contributions to the Control of Human Locomotion: Clinical and Fundamental Aspects
Many neurological patients express enhanced deficits while walking in a dark room (or during the night): the supraspinal structures involved in this navigational deficit have not been identified yet.
- Trial name
- SUPLOCO (NCT02263560)
- Testing
- Kinematic measurements
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Cerebrovascular Stroke, Body Composition
Assessment of Body Composition, Fatigue, Mobility and Functional Status in Post-Stroke Individuals
The goal of this randomized controlled trial is to evaluate body composition, fatigue, mobility level, functional status in with stroke individuals.
- Trial name
- NCT06255145
- Testing
- Bioelectrical Impedance Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Stroke
Reproducibility Study of Transcranial Doppler
Hardening of the neck vessels (carotid arteries) caused by fatty deposits called 'plaques' is a common cause of strokes. Over time plaques can burst or may lead to a severe narrowing (stenosis) of the neck artery.
- Trial name
- NCT03050567
- Testing
- Transcranial Doppler Ultrasound
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Stroke
Post-stroke Psychosocial Recovery
Stroke is a neurological injury that adversely impacts psychosocial functioning and quality of life. This may occur due to direct insult to the brain circuits integral to adaptive psychosocial functioning, and/or indirectly via…
- Trial name
- NCT05380037
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Acute Stroke
Multi-"Omics" Research of Danhong Injection to Treat Acute Ischemic Stroke
The purpose of this study is to explore the pharmacological mechanism of Danhong injection in the treatment of acute ischemic stroke.
- Trial name
- NCT02176395
- Testing
- Danhong injection, Standard medical care
- Where
- 4 sites in China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- China Academy of Chinese Medical Sciences
Stroke, Healthy Adult
Effects of a Robot-based Sensorimotor Upper Limb Rehabilitation Paradigm in Chronic Stroke
Sensorimotor function of the upper limb is commonly impaired after stroke, even in the chronic phase (>6 months post-stroke). Nevertheless, good sensorimotor function is needed for daily life functioning.
- Trial name
- RCT ROBUST (NCT07547800)
- Testing
- ROBUST, Kinarm therapy
- Where
- Belgium
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke
RCT of HeartBot in Women
The goal of this clinical trial is to find out whether an app-based program called HeartBot II, which uses an artificial intelligence (AI) chatbot, can help improve women's awareness and knowledge of heart attacks in women.
- Conditions
- Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke, Participants Should Have no Terminal Illness or Diagnosed Cognitive Impairment, Including Alzheimer's Disease, Participants Should Not be a Healthcare Professionals or Healthcare Trainees
- Trial name
- HeartBot II (NCT07416734)
- Testing
- HeartBot II Program, Waitlist Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stroke
SMARTCap Stroke Study: A Field Deployable Blood Test for Stroke
The hypothesis is that a stroke causes release of purines from brain into blood and that this is a very early biomarker of brain ischaemia.
- Trial name
- SMARTCAP (NCT02308605)
- Testing
- SMARTCap
- Where
- 2 sites in United Kingdom
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Acute Effect of Local Vibration Application in Stroke Patients
Acute Effect of Local Vibration in Stroke Patients
The aim of the research is to examine the acute effect of local vibration application on gait and balance in stroke patients.
- Trial name
- NCT06610994
- Testing
- local vibration apply
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Brain Diseases, Central Nervous System Diseases
Digital Diagnostics and Intervention Services for Parkinson's Disease
People with Parkinson's have infrequent clinical consultation (once every 12-18 months) and limited rehabilitation. Assessment play an important role in these consultations to help clinicians understand patients' health status…
- Conditions
- Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Joint Diseases
- Trial name
- NCT06534177
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Exeter
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