Clinical trials: stroke
Stroke, Silent Cerebral Infarction
Intervention With Cerebral Embolic Protection in TEVAR: Gaseous Protection
Vascular brain infarction (VBI) occurs in 67% of patients undergoing TEVAR. Overt stroke occurs in 13% of these patients and 88% of patients suffer from neurocognitive impairment.
- Conditions
- Stroke, Silent Cerebral Infarction, Neurocognitive Dysfunction, Vascular Brain Injury
- Trial name
- INTERCEPT:GP (NCT03886675)
- Testing
- CO2 flushing, Saline flushing
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Stroke, Ischemic Stroke
Salicornia for Neurovascular Health Improve
The purpose of this study is evaluate the effect and safety of the administration of a food supplement based on halophyte plant extracts versus placebo in the neurovascular healthy.
- Conditions
- Stroke, Ischemic Stroke, Neurovascular Injury, Brain Ischemia
- Trial name
- NCT06076122
- Testing
- Food supplement based on Salicornia extracts
- Where
- Spain
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Cardiovascular Diseases, Heart Diseases
The North Kynouria Project
The North Kynouria Project was initiated to study cardiovascular/stroke risk factors by employing mass screening and long-term surveillance of an adult population in the municipality of North Kynouria, in the county of Arcadia…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Cerebrovascular Disease, Coronary Disease
- Trial name
- NCT06115213
- Testing
- Patient counselling
- Where
- Greece
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ioannina
Stroke
Muscle Oxygenation in Stroke Patients
In addition to its many effects, physical movement is known to change both systemic blood circulation and muscle blood flow. In a study examining the effects of motor imagery, which produces effects similar to physical movement…
- Trial name
- NCT06106542
- Testing
- assessment
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Stroke, Cognitive Disorders
Post-stroke Cognitive Impairment and Dementia
Projections from epidemiological studies suggest that, among the Western adult population, one in three will present a cerebrovascular accident (stroke), severe cognitive disorders, or both.
- Conditions
- Stroke, Cognitive Disorders, Behavioral Disorders
- Trial name
- GRECogVASC (NCT01339195)
- Testing
- French adaptation of NINDS-Canadian Stroke Network battery
- Where
- 7 sites in France
- Volunteers
- 1,635 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Chronic Stroke, Weakness, Muscle
Use of Hand-held Dynamometry to Obtain Objective Measures of Lower Extremity Force Production With Chronic Stroke
This study wants to know if using handheld dynamometry (HHD) to test leg strength in persons who have had a stroke, will reduce mistakes and give therapists better information to use for therapy.
- Trial name
- NCT05941962
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cerebrovascular Disease, Stroke
Genetic Studies to Identify Stroke Subtypes and Outcome
This study will characterize the gene response of the body's immune and inflammatory cells to stroke. There is a wide variation in stroke risk, stroke outcome, and response to clot-busting therapy for stroke.
- Trial name
- NCT00357513
- Where
- 3 sites in United States
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Diabetes Mellitus, Type 2, Hypertension
Study of the Relationship Between Blood Vessels and Insulin Response in Adolescents
This study is designed to determine whether there is a relationship between the way insulin and blood vessels work. The difference in the interaction between Caucasian and African American adolescents will also be examined.
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Heart Disease, Stroke
- Trial name
- NCT00374361
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Respiratory Muscles, Stroke
The Effect of Functional Inspiratory Muscle Training Versus Inspiratory Muscle Training
This study aims to compare the effectiveness of functional inspiratory muscle training (IMT) versus inspiratory muscle training on trunk control, respiratory parameters, activity, and participation in chronic stroke patients.
- Trial name
- NCT06454539
- Testing
- Functional Inspiratory Muscle Training, Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Istinye University
Stroke, Transcranial Direct Current Stimulation
Hemodynamic Response of Anodal Transcranial Direct Current Stimulation Over the Cerebellar Hemisphere in Healthy Subjects
Upper extremity motor impairment is one of the major sequelae of stroke, resulting in limitation of activities of daily livings.
- Conditions
- Stroke, Transcranial Direct Current Stimulation, Functional Near Infrared Spectroscopy
- Trial name
- NCT04101695
- Testing
- tDCS
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Aphasia
Based on the Spatio-temporal Coding Characteristics of Frontotemporal Network, This Paper Explores the Mechanism of Five-tone Speech Training in Reshaping Language Fluency Function.
To explore the mechanism of five-tone speech training in reshaping language fluency function and the clinical efficacy of aphasia language function, daily communication ability and communication efficiency based on the temporal…
- Trial name
- NCT07329751
- Testing
- Traditional Chinese Medicine Five-Tone Therapy, Melodic Intonation Training, Standard speech therapy; Routine medical treatment; Health education
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fujian University of Traditional Chinese Medicine
Acquired Brain Injury
SAFIR© : An Early Intervention for Supporting Families of Patients With Acquired Brain Injuries
The aim of the study is to evaluate the feasibility of a newly developed intervention to improve family support for patient with acquired brain injury (ABI) in early phase of hospitalization (SAFIR): the main components are the…
- Trial name
- SAFIR© (NCT04138524)
- Testing
- SAFIR©
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Gait, Thermography
Effects of Treadmill-Based Gait Training in Patients With Stroke
Hemiplegia is one of the most common sequelae after stroke. Most patients develop thermal asymmetry between the affected and contralateral sides of the body, as well as an asymmetric gait pattern characterized by differences in…
- Conditions
- Gait, Thermography, Walking Speed, Mesh id D000072797, Endurance
- Trial name
- TreadmillACV (NCT07127861)
- Testing
- Treadmill gait training, CONVENTIONAL PHYSIOTHERAPY
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Acquired Brain Injury Including Stroke, Epilepsy
Cognitive Rehabilitation Using Neurofeedback With Brain-computer Interface
The goal of this clinical trial is to determine whether a Brain-Computer Interface Neurofeedback Training (BCI-NFT) programme can improve cognitive outcomes, and whether electroencephalography (EEG)-based measures can serve as…
- Trial name
- NCT07828496
- Testing
- Brain-computer interface with neurofeedback with 3D game sessions
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Stroke, Ischemic
Dose-finding Study of Selective Serotonin Reuptake Inhibitors to Enhance Neuroplasticity
The brain is able to change throughout life in response to learning, or injury, or to adapt to changes in the environment, which is known as neuroplasticity.
- Trial name
- NCT04221256
- Testing
- Administration of SSRI escitalopram, Paired Associative stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Burke Medical Research Institute
Pusher Syndrome
Combining Physical Therapy With Vestibular Stimulation to Improve Postural Stability in Pusher's Syndrome
The study is evaluating the effect of combining Galvanic Vestibular Stimulation (GVS) with standard Physiotherapy treatment in patients admitted to a neurological rehabilitation unit with Pusher syndrome (PS).
- Trial name
- NCT03831594
- Testing
- Galvanic Vestibular Stimulation, Standard Physiotherapy
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Stroke
Stroke Rehabilitation Using Brain-Computer Interface (BCI) Technology
The purpose of this research is to determine if functional muscle stimulation, directed by electroencephalogram (EEG) output, can increase the extent of stroke recovery on behavioral measures and induce brain plasticity as…
- Trial name
- NCT04141774
- Testing
- Functional Electric Stimulation (FES), Behavioral Assessments, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cerebellar Stroke, Autoimmune Cerebellar Disorders
Brain Stimulation to Improvement After Cerebellar Damage
The work will examine the mechanisms and potential therapeutic effects of transcranial magnetic stimulation on upper-limb sensorimotor function in individuals with cerebellar dysfunction, including those with damage due to stroke…
- Trial name
- NCT07838961
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- George Wittenberg
Hemorrhage
Comparison of Compensatory Reserve Index to Intravascular Volume Change and Stroke Volume
This study is designed to validate implementation of the CRI algorithm in the CypherOx CRI system. Healthy human subjects will undergo progressive reduction in central blood volume to the point of hemodynamic instability (defined…
- Trial name
- NCT01935427
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Flashback Technologies
Stroke
Efficacy of an Interactive Web-Based Home Therapy Program After Stroke
This is an online study that involves assessment and training of arm function at home. Stroke is the leading cause of disability worldwide.
- Trial name
- STRONG (NCT03484182)
- Testing
- Web-based Home Exercise Program, Standard Home Exercise Program
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
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