Clinical trials: stroke
Stroke
Efficacy of Robot-Assisted Rehabilitation of Hand Paralysis After Stroke
Among robotic devices, Gloreha, with its compliant mechanical transmission, may represent an easily applied innovative solution to rehabilitation, because the hand can perform grasp and release activities wearing the device by…
- Trial name
- NCT02711787
- Testing
- Experimental group, Control group, traditional rehabilitation
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Myocardial Infarction, Ischemic Stroke
Understanding the Role of Autoimmune Disorders on the Initial Presentation of Cardiovascular Disease
Autoimmune diseases are diseases in which inappropriate immune responses that have the capability of harming host cells play an important role.
- Conditions
- Myocardial Infarction, Ischemic Stroke, Stroke, Subarachnoid Haemorrhage
- Trial name
- NCT02062021
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Chronic Kidney Diseases, Heart Attack
Chronic Kidney Disease (CKD) Platelet Study
This study evaluates how aspirin, clopidogrel and ticagrelor work in people with chronic kidney disease (CKD) compared to people with normal kidneys.
- Conditions
- Chronic Kidney Diseases, Heart Attack, Stroke, Ischemic
- Trial name
- NCT03649711
- Testing
- Ticagrelor 90mg, Clopidogrel 75mg, Aspirin 81 mg
- Where
- 2 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Healthy, Stroke
Physiology of Interregional Connectivity in the Human Brain
The purpose of this study is to understand the physiology of connectivity between cortical regions in the human brain in healthy participants and in patients with white matter lesions.
- Conditions
- Healthy, Stroke, Traumatic Brain Injury, Multiple Sclerosis
- Trial name
- NCT03723434
- Testing
- Single-pulse transcranial magnetic stimulation (spTMS), Paired associative stimulation (PAS), Repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Traumatic and/or Non-traumatic Brain Injury
Assessing Special Features of Impaired Gait After Acquired Brain Injury With an Instrumented Treadmill
Hemiparetic gait following acquired brain injury (ABI) is grossly characterized by decreased speed of walking, increased stance time on the unaffected side, and decreased stance time on the affected side.These abnormalities are…
- Trial name
- NCT01413321
- Where
- Israel
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Stroke, Sympathetic Disorder
Contrast Bath and Sympathetic Skin Response
This study evaluates the effects of contrast bath on sympathetic skin response in stroke patients with complex regional pain syndrome .
- Trial name
- NCT04198532
- Testing
- Contrast bath
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Brain Health
Brain Health in the Time of COVID-19
This is a nationwide research program to study the neurological effects of COVID-19. It is open to the public. Healthy individuals and individuals who are or have been infected with COVID-19 are encouraged to join the effort.
- Trial name
- NCT04438967
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Miro Health
Type 2 Diabetes, Coronary Heart Disease
NMR Metabolomics-Based Risk Assessment and Stratified Digital Health Interventions in Middle-Aged Adults (PREMAP)
PREMAP invites residents of the Eloisa region (South Savo, Finland) turning 45, 50, or 55 years of age in 2026 to undergo a blood-based NMR metabolomics risk assessment for five interlinked cardio-renal-metabolic conditions (type…
- Conditions
- Type 2 Diabetes, Coronary Heart Disease, Myocardial Infarction, Cerebrovascular Disease
- Trial name
- PREMAP (NCT07820800)
- Testing
- Digital health interventions
- Where
- Finland
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Chronic Stroke-related Upper-extremity Motor Impairment, Motor Module-guided Rehabilitation Targeting Impaired Intermuscular Coordination and Motor Recovery
Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction in Chronic Stroke
The objective of this study is to develop Neuro-Intermuscular Coordination Enhancement (NICE) rehabilitation, a novel neuromuscular control signal-guided strategy that visually guides stroke patients to individually activate…
- Trial name
- NICE (NCT07531264)
- Testing
- Neuromuscular coordination enhancement (NICE) intervention, EMG Amplitude Biofeedback Exercise
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Houston
Stroke
Exoskeletal Support in Stroke
This interventional study will measure motor performance, including 3D movement analysis and muscle activity, in response to exoskeleton assistance. The cohort design will compare stroke patients to healthy controls.
- Trial name
- NCT05996198
- Testing
- Oculus Rift headset, Exoskeleton Device
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Stroke
The SMARTChip Stroke Study
Stroke is one of the leading causes of death and disability in the UK and currently costs the country £7bn per year. There is an overwhelming need to accurately and rapidly triage patients to allow best use of finite NHS…
- Trial name
- NCT02795481
- Where
- United Kingdom
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Stroke
Effects of Voluntary Adjustments During Walking in Participants Post-stroke
People post-stroke retain the capacity to modify walking patterns explicitly using biofeedback and implicitly when encountering changes in the walking environment.
- Trial name
- NCT06034119
- Testing
- Split belt treadmill, Biofeedback
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chapman University
Ulcerative Colitis, Myocardial Infarction
Estimation of Cardiovascular Risk in Patients With Crohn's Disease and Ulcerative Colitis (PROVACI)
Inflammatory bowel diseases (IBD) are progressively increasing their prevalence worldwide. Up to half of patients may also have extraintestinal manifestation and cardiovascular diseases (CVDs) is one of the most relevant, being…
- Conditions
- Ulcerative Colitis, Myocardial Infarction, Stroke, Ischemic Heart Disease
- Trial name
- PROVACI (NCT07095634)
- Where
- Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Amyotrophic Lateral Sclerosis, Brainstem Stroke
Optimizing BCI-FIT: Brain Computer Interface - Functional Implementation Toolkit
This project adds to non-invasive BCIs for communication for adults with severe speech and physical impairments due to neurodegenerative diseases.
- Conditions
- Amyotrophic Lateral Sclerosis, Brainstem Stroke, Muscular Dystrophies, Parkinson's Disease and Parkinsonism
- Trial name
- BCI-FIT (NCT04468919)
- Testing
- BCI-FIT multi-modal access, BCI-FIT adaptive signal modeling, BCI-FIT active querying
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Stroke
Noninvasive Brain Stimulation for Stroke
Noninvasive brain stimulations will be used in acute and chronic stroke patients to improve a variety of functions.
- Trial name
- NIBSstroke (NCT01503073)
- Testing
- tdcs (ELDITH, Neuroconn, Ilmenau, Germany)
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Stroke Patients
Feasibility and Reliability of Using BeCureTM Virtual Reality in Patients With Stroke
The aim of this study is to demonstrate the feasibility and reliability of using virtual reality-based BeCureTM in the assessment of upper extremity motor functions in stroke patients.It is necessary to define the appropriate…
- Trial name
- cros-sectional (NCT06696469)
- Testing
- Feasibility and reliability of using BeCureTM Virtual Reality in the evaluation of upper extremity motor functions in stroke patients
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ankara University
Stroke, Vascular Diseases
Passive Limb Movement Study
Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance.
- Conditions
- Stroke, Vascular Diseases, Ischemic
- Trial name
- PLM (NCT05935670)
- Testing
- Ischemic Conditioning
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Cerebral Amyloid Angiopathy, Intracranial Hemorrhages
Application of Amyloid PET in Cerebral Amyloid Angiopathy
In this project, we will try to enhance the diagnostic potentials of amyloid PET in CAA by combination of dynamic amyloid PET with MRI SWI and MR perfusion images.
- Conditions
- Cerebral Amyloid Angiopathy, Intracranial Hemorrhages, Alzheimer Disease
- Trial name
- CAA (NCT03542656)
- Testing
- amyloid PET
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healthy, Blindness
Multisensory Body and Space Representations (BASES-EXTINCTION)
To accurately control body movements to interact with objects, our brain needs representations of the body and the nearby space.
- Trial name
- NCT03201341
- Testing
- Electrooculogram (EOG), Surface Electromyography (EMG), Electrodermal response
- Where
- France
- Volunteers
- 1,540 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Stroke, Stroke, Acute
Looking Glass: Bimanual Balanced Reaching With Visual Biofeedback
The goal of this research study is to increase understanding of error augmentation by applying it to visual feedback during motion tracking with a Leap Motion device - a recently developed optical hand tracking tool - and the…
- Conditions
- Stroke, Stroke, Acute, Healthy
- Trial name
- NCT03300141
- Testing
- Veridical Visual Feedback, Augmented Visual Feedback, Healthy Comparative Reaching Task
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
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