Clinical trials: stroke
Cerebrovascular Disorders, Spasticity, Muscle
The Effect of Ultrasound-Guided Botulinum Toxin Injections on Pain, Functionality, Spasticity, and Range of Motion in Patients With Post-Stroke Upper Extremity Spasticity
The patients between the ages of 35-80 who developed spasticity in the upper extremity after stroke will be included.. Botulinum toxin(BT-A) injection will be applied to the study group(n=16) and placebo injection to the control…
- Conditions
- Cerebrovascular Disorders, Spasticity, Muscle, Botulinum Toxin
- Trial name
- NCT05887479
- Testing
- Botulinum toxin type A, %0,9 NaCl
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Stroke
The Effects of Fresnel Prism Glasses on Visual Perception, Balance, Gait and Functional Independence in Post-Stroke Patients
This randomized controlled trial aims to evaluate the effects of Fresnel prism glasses on visual perception, balance, gait, and functional independence in post-stroke patients.
- Trial name
- NCT07308054
- Testing
- Fresnel Prism Glasse, Convetional physical therapy
- Volunteers
- 50 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Brain Damage, Hypoxic, Stroke
ESWT for Shoulder Pain in Patients With Brain Damage
This study aimed to investigate the efficacy and safety of extracorporeal shockwave therapy (ESWT) for upper extremity pain related to spasticity in patients with spinal cord injury.
- Conditions
- Brain Damage, Hypoxic, Stroke, Brain Tumor, ICH
- Trial name
- NCT04320108
- Testing
- Extracorporeal shockwave therapy
- Where
- South Korea
- Volunteers
- 6 people
- Sponsor
- Bundang CHA Hospital
Acute Ischemic Stroke AIS
The STem Cell-derived Extracellular Vesicle Therapy In Acute Ischemic Stroke (STEVIA)
This is a multicenter open-label, single-arm, dose escalation phase I clinical trial to evaluate the safety and tolerability of SNE-101 in patients with acute ischemic stroke
- Trial name
- STEVIA (NCT06995625)
- Testing
- SNE-101
- Where
- 3 sites in South Korea
- Volunteers
- 18 people
- Sponsor
- S&Ebio Co. Ltd.
Cerebral Infarction, G6PD Deficiency
G6PD Deficiency in Infarction Patients in Shaanxi Province
Cerebral infarction brings heavy burden to patients and families with high morbidity, mortality, disability and recurrence rate.
- Trial name
- GPS-IP (NCT05026489)
- Testing
- G6PD gene deficiency
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Atrial Fibrillation, Stroke
Assessing the Neurological Outcomes After Atrial Fibrillation Ablation for Rhythm Control
A prospective, non-blinded, multi-center study to assess the impact of early Catheter Ablation (CA) in patients with a new diagnosis of Atrial Fibrillation(AF) at the time of stroke. 100 patients will be enrolled.
- Trial name
- SAVE STROKE II (NCT06783868)
- Testing
- Catheter Ablation, Market-approved AVNB, OAC and AAD
- Where
- 7 sites in United States
- Volunteers
- 100 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Sedation of Cerebrovascular Ventilated Critical Care Patients
Sedation Depth in Neurocritical Care
Background: Sedation of the intensive care unit (ICU) patient is necessary to relieve the patient from pain, anxiety and agitation and to enable mechanical ventilation, diagnostic investigations and invasive procedures.
- Trial name
- MODERNISE (NCT02317497)
- Testing
- Intensive Care Sedation (depth, level), Vasopressors to maintain normal blood pressure values, if needed, Osmotherapeutics to lowr intracranial pressure, if needed
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Heidelberg University
SARS-CoV-2, Post-stroke Depression
Depression, Anxiety and SARS-CoV-2 (Covid-19) Phobia in Post-stroke Patients
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has begun, first in Wuhan, China, and then became a pandemic. The first SARS-CoV-2 case in Turkey was reported on March 11, 2020.
- Conditions
- SARS-CoV-2, Post-stroke Depression, Anxiety and Fear
- Trial name
- NCT04560413
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Healthy, Stroke, Acute
Study of Cerebral Activation by fNIRS During Vibration-induced Illusion of Movement in Healthy and Stroke Participants.
The purpose of this study is to investigate the cerebral activation of healthy and stroke participants in 4 or 2 different conditions (repeated 2 times) of vibration-induced illusion of movement respectively, resulting in 8 or 4…
- Trial name
- VIBRANIRS (NCT06218563)
- Testing
- vibration-induced illusion of movement
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Stroke
Comparison of Exergaming Training With Visual Feedback Training on Upper Limb Functions in Post Stroke Patients
Stroke is classically characterized as a neurological deficit attributed to an acute focal injury of the central nervous system (CNS) by a vascular cause, including transient ischemic attack, cerebral infarction, intracerebral…
- Trial name
- NCT05673421
- Testing
- Exergaming Training, Visual Feedback Training
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Stroke, Brain Injuries
Efficacy of an Attentional Process Training Using Competitive Versus Non Competitive Strategies
Within a prospective, randomised, controlled study 60, selected patients with chronic (> 6 months) stroke or traumatic brain injury will be randomised to 30 1-hour sessions of competitive versus non-competitive attentional…
- Trial name
- NCT02220816
- Testing
- Competitive training, Non-Competitive Training
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospitales Nisa
Cerebral Infarction, Brain Ischemia
Penumbral Based Novel Thrombolytic Therapy in Acute Ischemic Stroke
Rationale The only proven therapy for acute stroke is tPA within 4.5 hours of symptom onset. This is the standard of care for patients presenting to our hospital within that time frame.
- Conditions
- Cerebral Infarction, Brain Ischemia, Stroke
- Trial name
- TIAS (NCT02101606)
- Testing
- Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Stroke, Ischemic, Aphasia
Individualized Precision rTMS for Language Recovery in Patients After Ischemic Stroke: a Multi-center RCT
The current multi-center study aims to evaluate the efficacy and safety of pBFS-guided rTMS Neuromodulation Treatment for the rehabilitation of language functions in ischemic stroke aphasic patients.
- Trial name
- NCT05842304
- Testing
- active cTBS
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Changping Laboratory
Stroke, Ischemic, Intravascular Thrombosis
Intra-arterial Neuroprotective Strategy for Ischemic STroke Patients With Endovascular Therapy (INSIST-ET)
To explore the safety and feasibility of intra-arterial neuroprotective strategy in acute ischemic stroke patients who received recanalization operation.
- Conditions
- Stroke, Ischemic, Intravascular Thrombosis, Mechanical Thrombectomy
- Trial name
- NCT04664933
- Testing
- Intra-arterial administration of neuroprotective agents
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Hui-Sheng Chen
Aphasia Following Cerebral Infarction
Intensive Comprehensive Aphasia Programme for People With Post-Stroke Aphasia
Research question Does participation in an Intensive Comprehensive Aphasia Programme produce a meaningful change in the communication of people with aphasia, their quality of life and that of their carers? Background Aphasia is a…
- Trial name
- RCT of an ICAP (NCT07386652)
- Testing
- ICAP, Standard Care (in control arm)
- Where
- United Kingdom
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- University College, London
Stroke
The Effect of Hand Massage on Pain, Anxiety, and Comfort Levels of Intensive Care Patients
This study titled "Evaluation of the Effect of Hand Massage on Patients' Pain, Anxiety and Comfort Levels" aims to determine the effect of hand massage on patients in intensive care units.
- Trial name
- NCT06808906
- Testing
- Hand Massage Application
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sakarya University
Ischemic Stroke
Brain-Machine Interface With Virtual Reality and Neuromuscular Electrical Stimulation for Upper Limb Rehabilitation After Stroke
Stroke is a major cause of long-term disability, and many stroke survivors experience persistent difficulties moving and using their affected arm and hand.
- Trial name
- NCT07911384
- Testing
- Brain-Machine Interface Training With Virtual Reality and NMES, Neuromuscular Electrical Stimulation
- Where
- Portugal
- Volunteers
- 68 people
- Sponsor
- Marta Sofia Ramos Torres
Peri-operative Stroke, Perioperative Adverse Events
Incidence and Risk Factors of Peri-operative Stroke in Non-cardiac,Non-neurosurgical Surgeries
Stroke is an important cause of perioperative morbidity and mortality, particularly in patients > 60 years. In cardiac, neurological and carotid surgery the incidence is known to be high (2.2-5.2%).
- Conditions
- Peri-operative Stroke, Perioperative Adverse Events, Non-cardiac Surgery, Non-neurosurgical Surgery
- Trial name
- POSIC (NCT01758952)
- Where
- 6 sites in China
- Volunteers
- 10,000 people
- Sponsor
- Chinese Medical Association
Stroke
External Validation of Two Prediction Models for Independent Gait After Stroke
Regaining independent gait is one of the main goals in stroke rehabilitation and early prediction of gait outcome is important to guide discharge planning at acute stroke units, design rehabilitation and inform patients and…
- Trial name
- REPEAT (NCT05039047)
- Testing
- Standard stroke acute care and rehabilitation
- Where
- Switzerland
- Volunteers
- 149 people
- Sponsor
- Janne Veerbeek
Stroke
Determine the Effect of Targeted High-definition Transcranial Direct Current Stimulation (tDCS) on Reducing Post-stroke Upper Limb Motor Impairments
Significant motor impairments occur in 80% of individuals after moderate to severe stroke and impact the body side to the lesioned hemisphere.
- Trial name
- NCT05479006
- Testing
- Transcranial direct current stimulation (high- definition)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Carle Foundation Hospital
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