Clinical trials: stroke
Acute Ischemic Stroke
Adjunctive Use of Intra-Arterial TNK and Albumin Following Thrombectomy
The purpose of this study is to investigate the feasibility and efficacy of intra-arterial TNK and albumin for patients with acute ischemic stroke after successful thrombectomy and whether there is a synergistic effect between…
- Trial name
- NCT06113848
- Testing
- Intra-Arterial TNK and Albumin, Intra-Arterial TNK, Intra-Arterial Albumin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Tianjin Huanhu Hospital
Stroke, Acute
Bobath Approach for Trunk Control in Acute Stroke Patients
In stroke patients, the impairment of the trunk affects many functions negatively. For this reason training of the trunk is necessary in the early period.
- Trial name
- NCT03429855
- Testing
- trunk training, physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Hacettepe University
Cognitive Decline, Dementia, Vascular
Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients
To test the effects of a 2- to 3-year intervention of the MIND diet versus usual post-stroke care on cognitive decline, the characteristic feature of dementia, and on brain biomarkers of Alzheimer's Disease (AD) and vascular…
- Conditions
- Cognitive Decline, Dementia, Vascular, Alzheimer Disease, Dementia
- Trial name
- NCT04337255
- Testing
- Behavioral Dietary intervention ( MIND Diet), Behavioral Usual Care Diet Intervention
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- Rush University Medical Center
Cerebral Stroke
Patients Undergoing Strokes Admitted in Intensive Care Requiring Neurosurgical ICU Crossing: Patient Profile and Prognosis
The aim of this study is to describe the population of patients admitted to the ICU in neurosurgery for stroke requiring secondary care in intensive care and their future.
- Trial name
- NCT02827825
- Testing
- No intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Stroke, Aphasia
Links Between Motor Abilities and Language Ability Deficits in Patients With Post-stroke Aphasia
Aphasia is a language disorder that affects oral and written expression and/or comprehension. It's one of the most disabling consequence of stroke.
- Trial name
- MOTOLANG-AVC (NCT05776368)
- Testing
- Syntactic comprehension battery (BCS), Montreal Cognitive Assessment (MOCA), Purdue Pegboard Test
- Where
- 3 sites in France
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Stroke
Effect of Lifestyle Changes on BDNF Level After Stroke
This is a pilot study to determine whether a lifestyle medicine intervention following stroke may increase levels of Brain-Derived Neurotrophic Factor (BDNF).
- Trial name
- NCT03701815
- Testing
- Wellness in Rehabilitation program
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- VA Palo Alto Health Care System
Stroke, Spasticity, Muscle
Multiphasic Neuroplasticity Based Training Protocol With Shock Wave Therapy For Post Stroke Spasticity
this study will be conducted to f find the effects of multiphasic neuroplasticity based training protocol with Shock Wave Therapy on Neurophysiological, Morphological and Functional Parameters of Post Stroke Spasticity.
- Trial name
- NCT05405140
- Testing
- Shock wave therapy with multiphasic neuroplasticity based training protocol, Conventional physical therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Stroke
Eccentric Contraction-based Resistance Exercise for Chronic Stroke Patients
The purpose of this study is to develop an evidence-based rehabilitation treatment method suitable for recovery and improvement of physical function in chronic stroke patients using an eccentric overload flywheel device.
- Trial name
- NCT04600050
- Testing
- usual care and exercise education, Eccentric exercise
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Bundang Hospital
Cerebral Small Vessel Diseases, Stroke, Lacunar
LACunar Intervention (LACI-2) Trial-2
About 35,000 people each year in the UK have a type of stroke, called 'lacunar' or 'small vessel' stroke, which is different to other common types of stroke and for which there is no proven treatment.
- Trial name
- LACI-2 (NCT03451591)
- Testing
- Isosorbide Mononitrate XL (ISMN), Cilostazol, ISMN XL and Cilostazol
- Where
- United Kingdom
- Volunteers
- 363 people
- Sponsor
- University of Edinburgh
Stroke
Effects of Kinesio Taping for Upper Limb Function of Stroke Patients
Patients with stroke in the brain, due to central nervous system damage, lack of correct action patterns, limited joint movement of upper limbs, affecting the patient's performance.
- Trial name
- NCT03935113
- Testing
- Kinesio taping
- Where
- Taiwan
- Volunteers
- 1 people
- Sponsor
- Taipei Medical University WanFang Hospital
Stroke
The Role of Peripheral Afferents in Modulating Post-stroke Central Pain
Central post-stroke pain (CPP) is extremely difficult to relieve and responds very poorly to analgesics targeting neuropathic pain, probably because the mechanisms underlying this pain remain poorly understood.
- Trial name
- APEDOC (NCT06446960)
- Testing
- Lidocaine 20mg/ml, Levobupivacaine Hydrochloride 1.25 MG/ML, Sodium Chloride 0.9% Inj
- Where
- 2 sites in France
- Volunteers
- 33 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Stroke
Compass 3: A Novel Transition Program to Reduce Disability After Stroke
This study evaluates a program designed to help individuals transition from inpatient rehabilitation to home following an ischemic or hemorrhagic stroke.
- Trial name
- COMPASS 3 (NCT07069660)
- Testing
- COMPASS, Education Program
- Where
- 2 sites in United States
- Volunteers
- 520 people
- Sponsor
- Washington University School of Medicine
Ischemic Heart Disease, Transient Ischemic Attack
TomVasc - Vascular Effects of Tomato Extract
Does tomato extract improve blood vessel function in healthy people and people with cardiovascular disease? Atherosclerosis ('furring' of the arteries) affects the functioning of blood vessels, narrowing and eventually blocking…
- Conditions
- Ischemic Heart Disease, Transient Ischemic Attack, Stroke, Peripheral Vascular Disease
- Trial name
- TomVasc (NCT01100385)
- Testing
- Ateronon
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Stroke
Transcranial Direct Current Stimulation to Improve Hand Movement in Stroke Patients
This study will examine whether hand movement in stroke patients can be improved by applying electrical stimulation to the side of the brain affected by the stroke.
- Trial name
- NCT00307385
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cardiac Output, Stroke Volume
Exercise Induced Plasma Volume Expansion Lowers Cardiovascular Strain
The goal of this observational study was to better understand the impact of increased plasma volume on later exercise in hypoxia. Investigators examined young, healthy, males who regularly participated in aerobic exercise.
- Trial name
- NCT05800808
- Testing
- High Intensity Intervals, Moderate Exercise
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- California Baptist University
Bulbar Palsy
Efficacy of Stellate Ganglion Block in Dysphagic Patients With Bulbar Palsy After Ischemic Stroke
This is a randomized controlled study, including dysphagic patients with bulbar palsy after ischemic stroke who were received in the department of rehabilitation medicine in 3 hospitals in China.
- Trial name
- NCT06225076
- Testing
- Comprehensive rehabilitation, Stellate ganglion block, Lidocaine Hydrochloride
- Where
- China
- Sponsor
- Zeng Changhao
Stroke
Cervical Proprioceptive Neuromuscular Facilitation and Stabilization Exercises in Stroke Patients
Randomization order tracking will be done with sequentially numbered containers. Patients participating in the study will be blinded as to which treatment group they will be included in.
- Trial name
- NCT06237140
- Testing
- PNF+ biofeedback exercise group
- Where
- Turkey (Türkiye)
- Sponsor
- Suleyman Demirel University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Stroke
A Pilot Clinical Trial Study to Determine the Safety of the Application of a Wearable Medical Electromagnetic Generator
To explore the safety of applying repetitive low-frequency transcranial magnetic stimulation using a wearable medical electromagnetic generator in stroke patients.
- Trial name
- NCT06543797
- Testing
- wearable rTMS
- Volunteers
- 10 people
- Sponsor
- Bundang CHA Hospital
Hemiparesis as Late Effect of Cerebrovascular Disease
Role of Functional Translation After Immersive Virtual Reality Exposure in Persons With Stroke
This is a single-blinded randomized control trial aiming to explore the use of immersive virtual reality (VR) training in conjunction with real-life tasks therapy in 75 first time stroke patients with upper limb weakness.
- Trial name
- NCT04360460
- Testing
- Immersive virtual reality + related functional translation into real-life, Immersive virtual reality + non-related translation into real-life
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Loma Linda University
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