Clinical trials: type1diabetes
Type1diabetes
Two Narrative Medicine Interventions in Type 1 Diabetes
a randomized prospective study aims at comparing the impact of a "living theater" session with a simple "writing workshop " on emotional distress (Problem Areas in Diabetes Questionnaire PAID) and illness perception ( Illness…
- Trial name
- NCT03365349
- Testing
- participating in a session of "living theatre", writing workshop
- Volunteers
- 87 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypoglycemia, Type1diabetes
Effect of Fasting on Hypoglycemic Counterregulation in Type 1 Diabetes
Iatrogenic hypoglycemia is still considered to be the number one barrier to effective glycemic control in patients with type 1 diabetes (T1D).
- Trial name
- NCT05973799
- Testing
- Fasting, Feeding
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Cincinnati
Type 1 Diabetes Mellitus With Hypoglycemia, type1diabetes
Intermediate and Long Acting Insulin Young Children Type 1 Diabetes.
Background: Achieving glycemic control without risking hypoglycemia imposes a major challenge in the management of toddlers and preschool children with Type 1 diabetes(T1D).
- Trial name
- NCT04664764
- Testing
- Degludec, Glargine, NPH insulin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Type1diabetes, Insulitis
Pancreas Ultrasound Imaging in type1 Diabetes
The overall goal of this study is to develop and test a novel method involving ultrasound imaging, in order to detect the development of type 1 diabetes.
- Conditions
- Type1diabetes, Insulitis, Pancreas Inflamed
- Trial name
- NCT05482321
- Testing
- Definity Suspension for Injection
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
type1diabetes
Resistance Exercise and Cognition in People With Type 1 Diabetes
The aim of the current study is to determine the effects of resistance exercise on performance of the Paced Auditory Serial Addition Test and the Colour Trails Test.
- Trial name
- NCT05963152
- Testing
- Habitual Physical Activity, Morning Exercise, Afternoon Exercise
- Where
- Kuwait
- Volunteers
- 54 people
- Sponsor
- Dasman Diabetes Institute
type1diabetes
The Impact of Macronutrient Composition on Glucose Dynamics in Persons With Type 1 Diabetes
A randomized, open-label, three-arm crossover study will be conducted. The aim of the study is to determine the effect of different isocaloric diet macronutrient compositions (High-carbohydrate-Low-fat-Low-protein (HCLFLP)…
- Trial name
- HiLo21 (NCT05268705)
- Testing
- 7-day diet
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Steno Diabetes Center Copenhagen
type1diabetes, Hunger
Postprandial Gut Hormone Responses in Patients With Type 1 Diabetes Mellitus
The study will compare the postprandial responses to a test meal between subjects with type 1 diabetes and healthy control subjects, in terms of gut hormone levels, meal induced thermogenesis, hunger and satiety perception, as…
- Conditions
- type1diabetes, Hunger, Obesity
- Trial name
- NCT04430946
- Testing
- Standardized test meal
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Type1diabetes
Crosstalk Between Mucosal-Associated Invariant T (MAIT) Cells and the Gut Microbiota and Mucosa in the Development of Type 1 Diabetes in Children
To investigate in a prospective way changes in Mucosal-Associated Invariant T (MAIT) cells frequency, phenotype and function in link with the gut microbiota, gut integrity and the presence of Coxsackie virus B in two cohorts of…
- Trial name
- MAIT-DT1 (NCT05054361)
- Testing
- MAIT cells analysis, MAIT cytokines production analysis, Lactulose/Mannitol Test
- Where
- 2 sites in France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Hemodialysis, Type1diabetes
Improved Glycemic Control in Diabetic Patients in Hemodialysis Using Continuous Glucose Monitoring (CGM)
The 16-week trial is an open-label cross-over trial which includes heamodialysis patients with T2D and T1D on insulin therapy. During one period, patients carry a non-blinded CGM.
- Conditions
- Hemodialysis, Type1diabetes, Type2Diabetes
- Trial name
- NCT05678712
- Testing
- Access to CGM data (Dexcom G6)
- Where
- Denmark
- Volunteers
- 23 people
- Sponsor
- Aalborg University Hospital
Type1diabetes
Thrive With Type 1 Diabetes 2026
This study aims to learn whether a cognitive behavioral intervention can improve lifestyle and glucose targets for adults with type 1 diabetes.
- Trial name
- NCT07522866
- Testing
- TranS-C Intervention Arm, Attention Control Enhanced Usual Care (EUC) Arm
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Emory University
Type1diabetes, Diabetes
China Diabetes Type 1 Study (CD1S) by China Alliance for Type 1 Diabetes
The aim of the China Diabetes Type 1 Study (CD1S) is to conduct a nationwide type 1 diabetes (T1D) registry study in patients with T1D and in pediatric adolescent patients with diabetes who had an age of onset <= 20 years.
- Trial name
- NCT05498974
- Testing
- Standard type 1 diabetes management model constructed by China Alliance for Type 1 Diabetes in each center
- Where
- 11 sites in China
- Volunteers
- 20,000 people
- Sponsor
- Second Xiangya Hospital of Central South University
Type1diabetes
Very Low Carbohydrate Diets and Glucagon Response in T1DM
Despite major technological advances, management of type one diabetes mellitus (T1D) remains suboptimal, putting millions of people at risk for immediate and long-term complications.
- Trial name
- NCT04200391
- Testing
- Very low carbohydrate diet
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Boston Children's Hospital
type1diabetes
Accuracy of a Continuous Ketone Monitoring (CKM) System in Individuals With Type 1 Diabetes on Insulin Pump Therapy.
The goal of this 14-day randomized pilot trial is to assess the accuracy of a continuous ketone monitoring (CKM) system when compared to standard point-of-care capillary ketone monitors in individuals with type 1 diabetes on…
- Trial name
- CKM 1 (NCT06420518)
- Testing
- Ketogenic diets, 8-hour insulin-suspension period
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- McGill University
Type1diabetes, Fasting Hypoglycemia
Sahoor Meal Regimen for Patients With Type1 Diabetes
To examine effects of two approaches to sahoor meal consumption during Ramadan on blood sugar control and incidence of early day hypoglycemic episodes requring the discontinuation of fasting.
- Trial name
- NCT04864483
- Testing
- Meal timing in relation to time of starting the fast
- Where
- Saudi Arabia
- Volunteers
- 44 people
- Sponsor
- King Abdullah International Medical Research Center
Type1diabetes
A Evaluation of Systematic Intensive Therapy Using CGM/FGM in Clinical Diabetes Care
This study aims to analyse if intensive systematic treatment via internet and telephone during 4 months improved HbA1c for persons with type 1 diabetes which are already treated with CGM or FGM, and if the effect continuous for…
- Trial name
- NCT03474393
- Testing
- systematic intensive therapy
- Where
- Sweden
- Volunteers
- 117 people
- Sponsor
- Vastra Gotaland Region
Type1diabetes
Metabolic Adaptation to High-frequent Hypoglycaemia in Type 1 Diabetes
An experimental mechanistic study. The overall objective is to gain new knowledge about mechanisms involved in adaptation to recurrent hypoglycaemia in diabetes by investigating patients with type 1 diabetes and healthy controls.
- Trial name
- HypoADAPT (NCT05095259)
- Testing
- insulin human, Epinephrin, Muscle biopsy
- Where
- 2 sites in Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Type1diabetes
CGMIS 48-hour Feasibility Study
This is a single center, single arm non-randomized study of 48-hour CGMIS wear duration incorporating two meal-challenge tests to explore the performance of a single insertion combined glucose-sensing insulin delivery cannula.
- Trial name
- NCT05562206
- Testing
- CGMIS (Continuous Glucose Monitoring Infusion Set)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pacific Diabetes Technologies
Type1diabetes
Health Behavior Intervention for Adults With Type 1 Diabetes
Type 1 diabetes (T1D) affects approximately 2 million Americans, and only 2 in 8 young adults ages 18-31 years achieve glycemic targets (glycated hemoglobin A1C <7.0%).
- Trial name
- NCT05823142
- Testing
- CB Sleep
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Emory University
Type1diabetes
Mesenchymal Stromal Cells to Treat Type 1 Diabetes in Children and Adolescents
This is a combined phase 1 and 2 study in 66 subjects, male or female, between 7-21 years of age that have recently (< 6 months) been diagnosed with type 1 diabetes.
- Trial name
- NCT05061030
- Testing
- the ATMP Protrans
- Where
- Sweden
- Volunteers
- 66 people
- Sponsor
- Uppsala University Hospital
Adult Subjects With Type1Diabetes and Insulin Microsecretion
Dulaglutide and Insulin MicrosecretiON in Type 1 Diabetes
Some patients with type 1 diabetes (T1D) can still have some remaining insulin-positive cells in the pancreas and secrete little amounts of insulin.
- Trial name
- DIAMOND GLP1 (NCT03668470)
- Testing
- Dulaglutide
- Where
- 7 sites in France
- Volunteers
- 45 people
- Sponsor
- Hospices Civils de Lyon