Clinical trials: in Bangladesh
Body Composition Changes, Muscle Mass
Effects of Daily Magnesium Complex Supplementation on Body Composition in University Students
This study will investigate whether daily supplementation with 400 mg of magnesium from a triple magnesium complex containing magnesium glycinate, magnesium malate, and magnesium citrate can improve body composition in young…
- Conditions
- Body Composition Changes, Muscle Mass, Body Fat Percentage
- Trial name
- NCT07906678
- Testing
- Triple Magnesium Complex
- Where
- Bangladesh
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Noakhali Science and Technology University
Iron Deficiency Anaemia Due to Dietary Causes, Folic Acid Deficiency Anemia, Dietary
Prevalence and Impact of Micronutrient (Iron-Folic Acid) Deficiencies on the Health of Adolescent Girls in Coastal Areas of Bangladesh
Anemia and iron-folic acid (IFA) deficiencies are major nutritional concerns among adolescent girls in environmentally vulnerable coastal communities of Bangladesh.
- Conditions
- Iron Deficiency Anaemia Due to Dietary Causes, Folic Acid Deficiency Anemia, Dietary, Anemia
- Trial name
- IFA-AG-Coastal (NCT07903558)
- Testing
- Iron-Folic Acid and Zinc Supplementation, Vitamin C Supplementation
- Where
- Bangladesh
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Patuakhali Science and Technology University
Anterior Cruciate Ligament
Clinical Outcome of Intra-articular Injection of PRP in ACL Injury.
Brief Summary This study will evaluate whether an injection of platelet-rich plasma (PRP) improves pain and knee function in adults with MRI-confirmed partial tears of the anterior cruciate ligament (ACL), compared with…
- Trial name
- ACL (NCT07185802)
- Testing
- PRP injection, conventional conservative treatment (physical therapy, functional bracing, lifestyle modification)
- Where
- Bangladesh
- Volunteers
- 47 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Helicobacter Pylori Infection, Dyspepsia
Vonoprazan-based Versus Esomeprazole-based Triple Therapy for Helicobacter Pylori Eradication
The goal of this clinical trial is to compare the efficacy and safety of vonoprazan-based levofloxacin-containing triple therapy with esomeprazole-based levofloxacin-containing triple therapy for eradication of Helicobacter…
- Conditions
- Helicobacter Pylori Infection, Dyspepsia, Peptic Ulcer Disease, Helicobacter Pylori
- Trial name
- NCT07537634
- Testing
- vonoprazan-based triple therapy (VAL regimen), Esomeprazole-based triple therapy (EAL regimen)
- Where
- Bangladesh
- Volunteers
- 80 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Diabetes, Coronary Artery Disease
Randomized Comparison of Abluminus DES+ Sirolimus-Eluting Stents Versus Everolimus-Eluting Stents in Coronary Artery Disease Patients With Diabetes Mellitus Global
To compare in diabetic patients eligible for percutaneous coronary intervention (PCI) with minimal exclusion criteria, the efficacy and safety of Abluminus DES+ sirolimus- eluting stents (SES) versus XIENCE Everolimus-Eluting…
- Conditions
- Diabetes, Coronary Artery Disease, Acute Coronary Syndrome
- Trial name
- ABILITY (NCT04236609)
- Testing
- Abluminus DES+ Sirolimus Eluting Stent System (SES), XIENCE Everolimus Eluting Coronary Stent System (XIENCE family)
- Where
- 90 sites in Australia, Austria and 19 more
- Volunteers
- 3,050 people
- Sponsor
- Concept Medical Inc.
Melasma (Facial Melasma)
Efficacy and Safety of Triple-Combination Cream Plus Microneedling Along With Tranexamic Acid Versus Platelet-Rich Plasma in the Treatment of Moderate-to-Severe Melasma: A Randomized Comparative Study
Background Melasma is a chronic acquired pigmentary disorder characterized by symmetrical hyperpigmented macules and patches, predominantly affecting the face.
- Trial name
- NCT07893067
- Testing
- Group B (Triple Combination Cream + Microneedling + Platelet-Rich Plasma)
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Bangladesh Medical University
Hypertension, Cardiovascular Diseases
Efficacy of Counselling for the Prevention of Hypertension (ECoPH)
This study aims to evaluate the effectiveness of counseling interventions in promoting positive changes in hypertension markers among adult slum dwellers.
- Trial name
- ECoPH (NCT07012096)
- Testing
- counseling, leaflet and mhealth education for hypertension, Leaflets and mhealth education
- Where
- Bangladesh
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Bangladesh University of Health Sciences
Depression, Anxiety
Improving Women's Mental Health Through Tele-based Wellbeing Centres in Bangladesh.
1. Burden: Women in Bangladesh face a high mental health burden, with 22% experiencing mental disorders compared to 16% of men. Access to face to face psychological care is limited by stigma, financial barriers, restricted…
- Trial name
- NCT07890896
- Testing
- Tele-counselling, In-person counselling
- Where
- 2 sites in Bangladesh
- Volunteers
- 1,200 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Diabetes Mellitus, Diabetic Retinopathy (DR)
Improving Patient-centered Care for Diabetes in Bangladesh Through "Dynamic Integration" of Vision Care on the Demand Side
The goal of this clinical trial is to determine whether there is an increase in participant uptake of diabetes mellitus (DM) and diabetic retinopathy (DR) services and improved quality of patient-centered diabetic care resulting…
- Trial name
- NCT06968611
- Testing
- Education/information of risk, Free eye glasses
- Where
- 2 sites in Bangladesh
- Volunteers
- 640 people
- Sponsor
- Orbis
Diabetes Mellitus, Diabetic Retinopathy (DR)
Improving Patient-centered Care for Diabetes in Bangladesh Through "Dynamic Integration" of Vision Care on the Supply Side
The goal of this clinical trial is to determine whether integration of vision care into the DM treatment system, by providing specific recommendations to doctors for management of diabetes alongside feedback on positive eye exams…
- Trial name
- NCT06968637
- Testing
- care recommendations
- Where
- 2 sites in Bangladesh
- Volunteers
- 336 people
- Sponsor
- Orbis
Hypernatremia, Acute Watery Diarrhea
Hypernatremia Fluid Therapy in Childhood Diarrhoea
Hypernatremic dehydration is a life-threatening condition, particularly in children under two years of age, with mortality rates reaching up to as high as 19%.
- Trial name
- HOPE (NCT07884747)
- Testing
- Oral rehydration solution (ORS)
- Where
- Bangladesh
- Volunteers
- 268 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Pregnancy, Periodontal Diseases
Education-Based Oral Health Promotion Intervention During Pregnancy: Implementation Protocol in Bangladesh
In Bangladesh, over 95% of pregnant women suffer from gum disease (gingivitis or periodontitis), yet oral health is rarely included in standard pregnancy check-ups.
- Conditions
- Pregnancy, Periodontal Diseases, Oral Hygiene, Oral Health
- Trial name
- E-OHP (NCT07507045)
- Testing
- Integrated Oral Health Promotion Package (IOHPP)
- Where
- Bangladesh
- Volunteers
- 688 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Moderate Acute Malnutrition (MAM), Undernutrition
Effectiveness of Positive Deviance/Hearth in Treating Uncomplicated Moderate Acute Malnutrition in Children 6-59 Months in Mymensingh Division, Bangladesh
The goal of this clinical trial (cluster randomized controlled trial) is to learn whether a Positive Deviance/Hearth (PDH) intervention can effectively treat moderate acute malnutrition (MAM) and reduce relapse compared to…
- Conditions
- Moderate Acute Malnutrition (MAM), Undernutrition, Wasting
- Trial name
- PD/Hearth MAM (NCT07591064)
- Testing
- PD/Hearth is a behavioral change program that teaches caregivers how to cook and feed their children. A nutrient-dense meal using local ingredients will be fed to children during Hearth sessions., Standard of Care (Investigator Selected)
- Where
- Bangladesh
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- World Vision US
Gestational Weight Gain
Improving Maternal Nutrition in Matlab
Background: Maternal undernutrition and inadequate gestational weight gain (GWG) are prevalent in rural communities of low- and middle-income countries (LMICs).
- Trial name
- IMNiM (NCT04868669)
- Testing
- In-home, intensive nutrition counseling
- Where
- Bangladesh
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Head and Neck Squamous Cell Carcinoma
An Experimental Study to Compare Treatment Response and Toxicities of Concurrent Chemoradiation With Weekly Cisplatin and Three Weekly Cisplatin in Locally Advanced Head and Neck Cancer.
The aim of this study is to compare treatment responses and toxicities of concurrent chemo-radiation with weekly and three weekly Cisplatin in locally advanced Head \& Neck Cancer.
- Trial name
- HNC (NCT03998696)
- Testing
- Cisplatin 40 mg/m2, Cisplatin 100 mg/m2
- Where
- Bangladesh
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Heat Cramps, Heat Rash
Testing Interventions to Mitigate the Health Impact of Heatwaves on Primary School Children in Climate-vulnerable Districts of Bangladesh.
The goal of this clinical trial is to assess the impact of implementing a combination of heat education and school-based physical infrastructure interventions in reducing heat related illnesses and improving educational outcomes…
- Conditions
- Heat Cramps, Heat Rash, Heat Exhaustion, Heat Stress
- Trial name
- NCT07877935
- Testing
- Solar reflective paint, Bamboo ceiling with polyethylene foam, Heat education toolkit
- Where
- 2 sites in Bangladesh
- Volunteers
- 2,875 people, healthy volunteers welcome
- Sponsor
- BRAC University
Stroke, Spinal Cord Injuries (SCI)
ZEPU-AI1 Gait Robot Training Study (ZEPUAI1RCT)
Walking problems caused by stroke, spinal cord injury, or orthopedic surgery are common and can seriously limit a person's independence.
- Conditions
- Stroke, Spinal Cord Injuries (SCI), Gait Disorders, Neurologic
- Trial name
- NCT07735676
- Testing
- ZEPU-AI1 Gait Training and Evaluation System, Standard-of-Care Rehabilitation (Individualized Rehabilitation and Exercise)
- Where
- Bangladesh
- Volunteers
- 51 people
- Sponsor
- Bangladesh Medical University
Malocclusion, Corticotomy
Evaluation of Corticotomy-Assisted Canine Retraction Rate
The goal of this split-mouth randomized clinical trial is to evaluate the effectiveness of corticotomy on maxillary canine retraction rate compared to conventional orthodontic techniques.
- Conditions
- Malocclusion, Corticotomy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- BMU/2026/8506 (NCT07879066)
- Testing
- Experimental: Corticotomy¬-Assisted Canine Retraction, Active Comparator / Control: Conventional Canine Retraction
- Where
- Bangladesh
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Neurodevelopment Outcome, Linear Growth
Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA Study
MEDHA is a randomized controlled trial among 10-18 year old girls to examine the use-case of the United Nations International Multiple Micronutrient Antenatal Preparation (UNIMMAP) multiple micronutrient supplement (MMS)…
- Conditions
- Neurodevelopment Outcome, Linear Growth, Micronutrient Status, Bone Mineral Density
- Trial name
- MEDHA (NCT07695883)
- Testing
- Iron (60 mg)- folic acid (400 ug) [IFA], Multiple micronutrient supplement [MMS], Multiple micronutrient supplement Plus [MMS+]
- Where
- Bangladesh
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diarrhea Infectious, Algorithms
The Utility and Feasibility of Accessible Diarrhea Etiology Prediction Tool (ADEPT) in an Informal Healthcare Setting
Diarrheal disease remains a leading cause of morbidity and mortality for children under 5 globally. Accepted best practice for managing diarrhea in the absence of blood or suspicion of cholera is rehydration, however in resource…
- Conditions
- Diarrhea Infectious, Algorithms, Decision Support Systems, Clinical, Clinical Decision-making
- Trial name
- NCT07538531
- Testing
- Diagnostic test: Accessible Diarrhea Etiology Prediction Tool (ADEPT)
- Where
- Bangladesh
- Volunteers
- 30 people
- Sponsor
- Daniel Leung