Clinical trials: active, in Bangladesh
Iron Deficiency Anemia, Parenting Intervention
Long-term Impacts of Psychosocial Stimulation and Iron Supplementation
The goal of this observational follow-up study is to learn about the long-term effects of early childhood parenting interventions and iron supplementation on young adults in rural Bangladesh.
- Trial name
- NCT07919327
- Where
- Bangladesh
- Volunteers
- 379 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Decompensated Cirrhosis and Ascites
Low Dose Versus Standard Dose Albumin
Background: Liver cirrhosis with ascites is a major health problem, and large-volume paracentesis (LVP) is commonly performed for management of tense or refractory ascites.
- Trial name
- NCT07917819
- Testing
- Low dose Albumin, standard dose albumin
- Where
- Bangladesh
- Volunteers
- 25 people
- Sponsor
- Bangladesh Medical University
Isolation, Identification
Isolation of Probiotic Lactic Acid Bacteria From Bangladeshi Fermented Foods
Brief Summary This study focus on the presence of probiotic LAB in traditional Bangladeshi fermented foods such as Modhubhat, pickles, and yogurt.
- Conditions
- Isolation, Identification, Probiotic Characterization
- Trial name
- ProLab-BD (NCT07917065)
- Where
- Bangladesh
- Volunteers
- 45 people
- Sponsor
- Bangladesh Bioscience Research Group
Safety and Tolerability in Healthy Volunteers
Safety and Tolerability Evaluation of BP-LT
This study evaluates the safety and tolerability of the food ingredient BP-LT when added to a daily diet. BP-LT is a stable protein ingredient being functional in the gastrointestinal tract and without systemic absorption.
- Trial name
- NCT07819695
- Testing
- BP-LT
- Where
- Bangladesh
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bactolife A/S
Psoriasis
Comparison of Efficacy and Safety of Deucravacitinib Versus Methotrexate in the Treatment of Moderate-to-Severe Plaque Psoriasis .
Background: Psoriasis is a chronic , immune-mediated inflammatory skin disorder affecting millions globally, the disease presents a major challenge to the physicians.
- Trial name
- NCT07915492
- Testing
- Participants in group B will receive Methotrexate ,10mg tablets , once weekly for 28 weeks
- Where
- Bangladesh
- Volunteers
- 106 people
- Sponsor
- Bangladesh Medical University
Chronic Kidney Disease (Stage 3-4)
Effect of Synbiotic Therapy on Renal Function Outcomes in Patients With Chronic Kidney Disease Stage III-IV: A Double-blind Randomized Placebo-controlled Trial.
Background: Chronic kidney disease (CKD) represents a growing global public health challenge, with rising prevalence in low and middle-income countries, including Bangladesh.
- Trial name
- NCT07912359
- Testing
- Experimental arm will get synbiotic therapy containing Lactobacillus acidophilus (15 billion CFU), Bifidobacterium longum (15 billion CFU), Streptococcus thermophilus(15 billion CFU), along with xylo
- Where
- Bangladesh
- Volunteers
- 96 people
- Sponsor
- Chittagong Medical College
Body Composition Changes, Muscle Mass
Effects of Daily Magnesium Complex Supplementation on Body Composition in University Students
This study will investigate whether daily supplementation with 400 mg of magnesium from a triple magnesium complex containing magnesium glycinate, magnesium malate, and magnesium citrate can improve body composition in young…
- Conditions
- Body Composition Changes, Muscle Mass, Body Fat Percentage
- Trial name
- NCT07906678
- Testing
- Triple Magnesium Complex
- Where
- Bangladesh
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Noakhali Science and Technology University
Small Intestine Bacterial Overgrowth
Comparative Efficacy of Antibiotics for Small Intestine Bacterial Overgrowth in Bangladeshi Children
The purpose of this Phase IIa study is to identify the most effective antibiotic regimen to treat small intestine bacterial overgrowth (SIBO) in impoverished Bangladeshi children.
- Trial name
- NCT07451171
- Testing
- Trimethoprim-sulfamethoxazole (TMP/SMX), Metronidazole, Amoxicillin-Clavulanate (4:1 formulation)
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- University of Virginia
Melasma (Facial Melasma)
Efficacy and Safety of Triple-Combination Cream Plus Microneedling Along With Tranexamic Acid Versus Platelet-Rich Plasma in the Treatment of Moderate-to-Severe Melasma: A Randomized Comparative Study
Background Melasma is a chronic acquired pigmentary disorder characterized by symmetrical hyperpigmented macules and patches, predominantly affecting the face.
- Trial name
- NCT07893067
- Testing
- Group B (Triple Combination Cream + Microneedling + Platelet-Rich Plasma)
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Bangladesh Medical University
Hypertension, Cardiovascular Diseases
Efficacy of Counselling for the Prevention of Hypertension (ECoPH)
This study aims to evaluate the effectiveness of counseling interventions in promoting positive changes in hypertension markers among adult slum dwellers.
- Trial name
- ECoPH (NCT07012096)
- Testing
- counseling, leaflet and mhealth education for hypertension, Leaflets and mhealth education
- Where
- Bangladesh
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Bangladesh University of Health Sciences
Depression, Anxiety
Improving Women's Mental Health Through Tele-based Wellbeing Centres in Bangladesh.
1. Burden: Women in Bangladesh face a high mental health burden, with 22% experiencing mental disorders compared to 16% of men. Access to face to face psychological care is limited by stigma, financial barriers, restricted…
- Trial name
- NCT07890896
- Testing
- Tele-counselling, In-person counselling
- Where
- 2 sites in Bangladesh
- Volunteers
- 1,200 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Diabetes Mellitus, Diabetic Retinopathy (DR)
Improving Patient-centered Care for Diabetes in Bangladesh Through "Dynamic Integration" of Vision Care on the Demand Side
The goal of this clinical trial is to determine whether there is an increase in participant uptake of diabetes mellitus (DM) and diabetic retinopathy (DR) services and improved quality of patient-centered diabetic care resulting…
- Trial name
- NCT06968611
- Testing
- Education/information of risk, Free eye glasses
- Where
- 2 sites in Bangladesh
- Volunteers
- 640 people
- Sponsor
- Orbis
Diabetes Mellitus, Diabetic Retinopathy (DR)
Improving Patient-centered Care for Diabetes in Bangladesh Through "Dynamic Integration" of Vision Care on the Supply Side
The goal of this clinical trial is to determine whether integration of vision care into the DM treatment system, by providing specific recommendations to doctors for management of diabetes alongside feedback on positive eye exams…
- Trial name
- NCT06968637
- Testing
- care recommendations
- Where
- 2 sites in Bangladesh
- Volunteers
- 336 people
- Sponsor
- Orbis
Hypernatremia, Acute Watery Diarrhea
Hypernatremia Fluid Therapy in Childhood Diarrhoea
Hypernatremic dehydration is a life-threatening condition, particularly in children under two years of age, with mortality rates reaching up to as high as 19%.
- Trial name
- HOPE (NCT07884747)
- Testing
- Oral rehydration solution (ORS)
- Where
- Bangladesh
- Volunteers
- 268 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Pregnancy, Periodontal Diseases
Education-Based Oral Health Promotion Intervention During Pregnancy: Implementation Protocol in Bangladesh
In Bangladesh, over 95% of pregnant women suffer from gum disease (gingivitis or periodontitis), yet oral health is rarely included in standard pregnancy check-ups.
- Conditions
- Pregnancy, Periodontal Diseases, Oral Hygiene, Oral Health
- Trial name
- E-OHP (NCT07507045)
- Testing
- Integrated Oral Health Promotion Package (IOHPP)
- Where
- Bangladesh
- Volunteers
- 688 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Moderate Acute Malnutrition (MAM), Undernutrition
Effectiveness of Positive Deviance/Hearth in Treating Uncomplicated Moderate Acute Malnutrition in Children 6-59 Months in Mymensingh Division, Bangladesh
The goal of this clinical trial (cluster randomized controlled trial) is to learn whether a Positive Deviance/Hearth (PDH) intervention can effectively treat moderate acute malnutrition (MAM) and reduce relapse compared to…
- Conditions
- Moderate Acute Malnutrition (MAM), Undernutrition, Wasting
- Trial name
- PD/Hearth MAM (NCT07591064)
- Testing
- PD/Hearth is a behavioral change program that teaches caregivers how to cook and feed their children. A nutrient-dense meal using local ingredients will be fed to children during Hearth sessions., Standard of Care (Investigator Selected)
- Where
- Bangladesh
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- World Vision US
Heat Cramps, Heat Rash
Testing Interventions to Mitigate the Health Impact of Heatwaves on Primary School Children in Climate-vulnerable Districts of Bangladesh.
The goal of this clinical trial is to assess the impact of implementing a combination of heat education and school-based physical infrastructure interventions in reducing heat related illnesses and improving educational outcomes…
- Conditions
- Heat Cramps, Heat Rash, Heat Exhaustion, Heat Stress
- Trial name
- NCT07877935
- Testing
- Solar reflective paint, Bamboo ceiling with polyethylene foam, Heat education toolkit
- Where
- 2 sites in Bangladesh
- Volunteers
- 2,875 people, healthy volunteers welcome
- Sponsor
- BRAC University
Malocclusion, Corticotomy
Evaluation of Corticotomy-Assisted Canine Retraction Rate
The goal of this split-mouth randomized clinical trial is to evaluate the effectiveness of corticotomy on maxillary canine retraction rate compared to conventional orthodontic techniques.
- Conditions
- Malocclusion, Corticotomy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- BMU/2026/8506 (NCT07879066)
- Testing
- Experimental: Corticotomy¬-Assisted Canine Retraction, Active Comparator / Control: Conventional Canine Retraction
- Where
- Bangladesh
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Neurodevelopment Outcome, Linear Growth
Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA Study
MEDHA is a randomized controlled trial among 10-18 year old girls to examine the use-case of the United Nations International Multiple Micronutrient Antenatal Preparation (UNIMMAP) multiple micronutrient supplement (MMS)…
- Conditions
- Neurodevelopment Outcome, Linear Growth, Micronutrient Status, Bone Mineral Density
- Trial name
- MEDHA (NCT07695883)
- Testing
- Iron (60 mg)- folic acid (400 ug) [IFA], Multiple micronutrient supplement [MMS], Multiple micronutrient supplement Plus [MMS+]
- Where
- Bangladesh
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Polycystic Ovary Syndrome, Metformin
Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS
The aim of this study is to see the associations of metabolic responses of metformin with single nucleotide polymorphisms (SNPs) (rs628031 and rs2282143) of solute carrier family 22 member 1 (SLC22A1) gene in women with…
- Trial name
- NCT05680805
- Testing
- Metformin Hydrochloride
- Where
- Bangladesh
- Volunteers
- 150 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh