Clinical trials: in Bolivia
Mucocutaneous Leishmaniasis
Spermiogram Assessment in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous Leishmaniasis
This study is a Phase 4, open-label, single group study in which at least 55 evaluable adult male patients undergoing miltefosine treatment for mucocutaneous leishmaniasis will provide semen samples for spermiogram analysis of…
- Trial name
- NCT02431429
- Testing
- Miltefosine
- Where
- Bolivia
- Volunteers
- 55 people
- Sponsor
- Knight Therapeutics (USA) Inc
Adolescent Pregnancy, Preeclampsia and Eclampsia
Blood Pressure in Adolescents With PReclampsia and Eclampsia.
Levels of blood pressure in adolescents with preeclampsia and eclampsia: Multicenter case-control study (Latin America). Maternities in Latin America: Two hospitals in Panama, one hospital in Mexico, one hospital in El Salvador…
- Trial name
- ADPRE (NCT03360240)
- Where
- 8 sites in Bolivia, Colombia and 4 more
- Volunteers
- 1,050 people
- Sponsor
- Complejo Hospitalario Dr. Arnulfo Arias Madrid
Copd
FEV1/FEV6 and FEV6 as an Alternative for FEV1/FVC and FVC in Bolivian Subjects
Comparison of FEV1/FEV6 and FEV6 as an alternative for FEV1/FVC and FCV in the detection of airway obstruction in a Bolivian population
- Trial name
- NCT03534557
- Testing
- FEV6 spirometry
- Where
- Bolivia
- Volunteers
- 70 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Chronic Disease
A Longitudinal Survey of Health in Bolivia
The purpose of the study is to gather baseline surveillance data about the current health status of adults with chronic health conditions in La Paz and El Alto, Bolivia and identify barriers to the management of NCDs during…
- Trial name
- NCT02384356
- Where
- 2 sites in Bolivia
- Volunteers
- 2,000 people
- Sponsor
- University of Michigan
Chagas Disease
Optimization of PCR Technique to Assess Parasitological Response for Patients With Chronic Chagas Disease
The purpose of this study is to estimate the gain in sensitivity of several multiple-sample strategies of PCR samples with respect to the current standard (single sample of 10 ml) to detect Chagas chronic stage at baseline and to…
- Trial name
- PCR (NCT01678599)
- Testing
- Benznidazole
- Where
- Bolivia
- Volunteers
- 220 people
- Sponsor
- Drugs for Neglected Diseases
Condylomata Acuminata, Papillomavirus Infections
Safety and Efficacy Study of Topical Ranpirnase to Treat Genital Warts (HPV)
Ranpirnase in topical formulation is an antiviral drug being evaluated for the topical treatment of anogenital warts. The aims of this study is to evaluate the efficacy and safety of a topical formulation of ranpirnase in…
- Conditions
- Condylomata Acuminata, Papillomavirus Infections, Sexually Transmitted Diseases
- Trial name
- NCT02535104
- Testing
- Ranpirnase, Vehicle
- Where
- Bolivia
- Volunteers
- 70 people
- Sponsor
- Tamir Biotechnology, Inc.
Chagas' Disease (Chronic) With Other Organ Involvement
Lower Urinary Tract Dysfunction in Chronic Chagas' Disease : Clinical and Urodynamic Presentation
Chagas disease is one of the most neglected vector-borne infectious disease worldwide. The first decades following the discovery of the pathology drove an international research enthusiasm, mainly concentrated on understanding…
- Trial name
- NCT03189056
- Testing
- Chagas serology, Creatinina, Urodynamic exploration
- Where
- Bolivia
- Volunteers
- 152 people
- Sponsor
- Institut de Recherche pour le Developpement
Acute Respiratory Failure
Third International Study on Mechanical Ventilation
The objective of this study is to obtain a better understanding of the spectrum of use of mechanical ventilation in intensive care units: 1.
- Trial name
- ISMV (NCT01093482)
- Where
- 477 sites in United States, Argentina and 36 more
- Volunteers
- 8,151 people
- Sponsor
- Hospital Universitario Getafe
Contraception
An Intervention Delivered by App Instant Messaging to Increase Use of Effective Contraception Among Young Women in Bolivia
This randomised controlled trial will establish the effect a contraceptive intervention delivered by mobile phone app instant messaging on use of effective contraception in Bolivia.
- Trial name
- NCT02905526
- Testing
- Contraceptive instant messages, Mobile phone app
- Where
- Bolivia
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Chagas Disease
BENDITA BEnznidazole New Doses Improved Treatment and Associations
Recent scientific advances have provided further impetus to develop new therapeutic approaches for Chagas Disease (CD) using different doses and duration of BZN, as well as combinations directed at multiple therapeutic targets to…
- Trial name
- BENDITA (NCT03378661)
- Testing
- Benznidazole, E1224
- Where
- 3 sites in Bolivia
- Volunteers
- 210 people
- Sponsor
- Drugs for Neglected Diseases
Diarrhea
Solar Water Disinfection Intervention Trial in Bolivia
The importance of waterborne gastrointestinal illness throughout the developing world, the existence of a cheap and effective intervention (SODIS), the concurrent limited dissemination program for SODIS, the need for a controlled…
- Trial name
- SODIS_Bolivia (NCT00731497)
- Testing
- Solar Water Disinfection (SODIS)
- Where
- 2 sites in Bolivia
- Volunteers
- 1,163 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Traumatic Brain Injury
Managing Severe Traumatic Brain Injury (TBI) Without Intracranial Pressure Monitoring (ICP) Monitoring Guidelines
Management of intracranial hypertension (ICH) in patients with severe traumatic brain injury (sTBI) is crucial to their survival and optimal recovery.
- Trial name
- NCT02059941
- Where
- 13 sites in Bolivia, Colombia and 2 more
- Volunteers
- 780 people
- Sponsor
- University of Washington
Pregnancy
Effectiveness of Two Regimens of Misoprostol Alone for Early Pregnancy Termination and Use of SQPT for At-Home Follow-Up
This randomized trial will compare the rates of ongoing pregnancy, safety/side effects and acceptability of two medical abortion regimens that are commonly used in Latin America.
- Trial name
- NCT02299401
- Testing
- Misoprostol, Semi-quantitative pregnancy test
- Where
- 2 sites in Bolivia, Ecuador
- Volunteers
- 401 people
- Sponsor
- Gynuity Health Projects
Parkinson's Disease
Mucuna Pruriens Therapy in Parkinson's Disease
In low-income areas worldwide, most patients with Parkinson's disease (PD) cannot afford long-term Levodopa therapy. A potential therapeutic option for them is the use of a legume called Mucuna Pruriens var.
- Trial name
- NCT02680977
- Testing
- MP-Equivalent, MP-Low, MP+DDCI
- Where
- Bolivia
- Volunteers
- 18 people
- Sponsor
- ASST Gaetano Pini-CTO
Depression
Developing Accessible mHealth Programs for Depression Management in Bolivia
The purpose of the study is to evaluate the feasibility and potential impact of an automated phone system in monitoring and improving self-care and health outcomes among patients with depression in Bolivia.
- Trial name
- NCT02765542
- Testing
- Automated disease assessment & self-care support phone calls
- Where
- Bolivia
- Volunteers
- 32 people
- Sponsor
- University of Michigan
Hypertension, Diabetes
Developing Accessible Telehealth Programs for Diabetes and Hypertension Management in Bolivia
The purpose of the study is to evaluate the feasibility and impact of an automated phone system in monitoring and improving self-care and health outcomes among patients with diabetes and/or hypertension in Bolivia, in addition to…
- Trial name
- NCT02429297
- Testing
- HITCM-only, HITCM+CP
- Where
- Bolivia
- Volunteers
- 110 people
- Sponsor
- University of Michigan
Acute Kidney Injury, Adverse Drug Reaction
The Drug Induced Renal Injury Consortium
Some medications are known to cause kidney damage because the person is allergic to the medication while others cause direct damage to the kidney because they are toxic at certain concentrations.
- Conditions
- Acute Kidney Injury, Adverse Drug Reaction, Acute Kidney Failure, Kidney Failure
- Trial name
- DIRECT (NCT02159209)
- Where
- 18 sites in United States, Bolivia and 4 more
- Volunteers
- 634 people
- Sponsor
- Ravindra Mehta
Obesity, Overweight
Effect of Physical Activity Through Interactive Video Games in Overweight Children
The purpose of this study is to determine the effect of interactive video game in management of overweight in children. The investigators will evaluate the effect of product versus standard physical activity.
- Trial name
- NCT02214108
- Testing
- Nintendo Wii
- Where
- Bolivia
- Volunteers
- 60 people
- Sponsor
- Centro Pediatrico Albina de Patino
Infectious Diseases
Sensitivity Study of Diagnostic for Detection of Chagas Infection
This study is a multi-site trial assessing the sensitivity of Chagas Detect™ Plus rapid test versus standard reference tests (e.g. IFA, IHA, RIPA) for Chagas diagnosis.
- Trial name
- NCT02134548
- Where
- 2 sites in Bolivia, Chile
- Volunteers
- 1,601 people
- Sponsor
- InBios International, Inc.
Incidence of VAT
International Multicenter Study of Ventilator Associated Tracheobronchitis.
Justification and background Ventilator-associated complications (VACs) are those complications that develop during a period of intubation of a patient .
- Trial name
- TAVeM (NCT01791530)
- Where
- 8 sites in Argentina, Bolivia and 6 more
- Volunteers
- 3,000 people
- Sponsor
- Corporacion Parc Tauli