Clinical trials: in Bolivia
Chagas Disease, Trypanosomiasis, South American
Study to Evaluate Fexinidazole Dosing Regimens for the Treatment of Adult Patients With Chagas Disease
The hypothesis is to evaluate if the treatment with Fexinidazole will lead to a better sustained clearance of the parasites at 6 months of follow-up when in comparison to placebo in patients with chronic indeterminate CD.
- Conditions
- Chagas Disease, Trypanosomiasis, South American, South American Trypanosomiasis, Disease, Chagas
- Trial name
- NCT02498782
- Testing
- Fexinidazole
- Where
- 2 sites in Bolivia
- Volunteers
- 140 people
- Sponsor
- Drugs for Neglected Diseases
Sexual and Reproductive Health Problems
Community-embedded Reproductive Health Care for Adolescents in Latin America.
Adolescents in Latin America are at major risk for unwanted pregnancies leading to unsafe abortions and maternal health risks. Mostly, adolescent health programmes tend to focus on unidirectional interventions aiming at a single…
- Trial name
- CERCA (NCT01722084)
- Testing
- Theory of planned behaviour (TPB) and social cognitive theory (SCT).
- Where
- 4 sites in Bolivia, Ecuador and 1 more
- Volunteers
- 9,625 people, healthy volunteers welcome
- Sponsor
- University Ghent
Acute Diarrhea, Acute Gastroenteritis
Efficacy of Use of Zinc in the Treatment of Acute Diarrhea in Infants
The purpose of this study is to determine the effect of zinc in acute watery diarrhea in children. The investigators will evaluate the effect of product versus placebo.
- Trial name
- NCT01571856
- Testing
- Zinc Sulfate
- Where
- Bolivia
- Volunteers
- 52 people
- Sponsor
- Centro Pediatrico Albina de Patino
Traumatic Brain Injury, Brain Injuries
Study to Improve Outcomes for Survivors of Traumatic Brain Injury in Latin America
People who survive severe traumatic brain injury (TBI) live with profound cognitive impairments that alter their developmental course and define their future possibilities.
- Trial name
- NCT01068522
- Testing
- Parenchymal Intracranial pressure monitor, Treatment based on clinical and imaging observations
- Where
- 6 sites in Bolivia, Ecuador
- Volunteers
- 324 people
- Sponsor
- University of Washington
Congenital Heart Disease
Safety and Effectiveness of the Device "Nit-Occlud® PDA-R"
The purpose of this study is to evaluate the safety and the effectiveness of the device "Nit-Occlud® PDA-R" in the percutaneous closure of patent ductus.
- Trial name
- NCT01063712
- Testing
- Nit-Occlud® PDA-R
- Where
- Bolivia
- Volunteers
- 29 people
- Sponsor
- pfm S.R.L.
Acute Diarrhea, Acute Gastroenteritis
Efficacy of Racecadotril in Acute Watery Diarrhea in Children
The purpose of this study is to determine the effect of racecadotril in acute watery diarrhea in children. The investigators will evaluate the effect of product versus placebo.
- Trial name
- NCT01577043
- Testing
- Racecadotril
- Where
- Bolivia
- Volunteers
- 52 people
- Sponsor
- Centro Pediatrico Albina de Patino
Acute Diarrhea, Acute Gastroenteritis
Use of Probiotic Yogurt in the Treatment of Acute Diarrhea in Children
The purpose of this study is to determine the effect of probiotic yogurt in acute watery diarrhea in children. The investigators will compare the effect of two different probiotics products.
- Trial name
- NCT01564290
- Testing
- Probiotic yogurt
- Where
- Bolivia
- Volunteers
- 54 people
- Sponsor
- Centro Pediatrico Albina de Patino
Chronic Chagas Disease, Indeterminate
Proof-of-Concept Study of E1224 to Treat Adult Patients With Chagas Disease
This study will assess the safety and efficacy of E1224, a pro-drug of ravuconazole, in individuals with chronic indeterminate Chagas disease recruited in research centres in Tarija and Cochabamba, Bolivia.
- Trial name
- NCT01489228
- Testing
- E1224, Benznidazole
- Where
- 2 sites in Bolivia
- Volunteers
- 230 people
- Sponsor
- Drugs for Neglected Diseases
Cutaneous Leishmaniasis
Oral Miltefosine Plus Topical Imiquimod to Treat Cutaneous Leishmaniasis
Cutaneous leishmaniasis is endemic in the New World from approximately the US-Mexican border through Central America and the Northern part of South America down to the level of Rio de Janeiro.
- Trial name
- NCT01380314
- Testing
- Miltefosine + Imiquimod
- Where
- Bolivia
- Volunteers
- 60 people
- Sponsor
- Foundation Fader
Cutaneous Leishmaniasis
Treatment of Cutaneous Leishmaniasis With a Combination of Miltefosine and Antimony
Cutaneous leishmaniasis is endemic in the New World and, until recently, the standard treatment was pentavalent antimony. The cure rate for L panamensis in Colombia is 91%-93% and the cure rate in Bolivia is also 90%.
- Trial name
- NCT01380301
- Testing
- Miltefosine and antimony, Miltefosine alone
- Where
- Bolivia
- Volunteers
- 19 people
- Sponsor
- Foundation Fader
Cutaneous Leishmaniasis
Miltefosine to Treat Cutaneous Leishmaniasis in Bolivia
Cutaneous leishmaniasis is typically treated with the parenteral product pentavalent antimony. Miltefosine is an oral agent shown to be active for mucosal leishmaniasis due to L braziliensis in Bolivia and cutaneous leishmaniasis…
- Trial name
- NCT00233545
- Testing
- miltefosine, antimony
- Where
- Bolivia
- Volunteers
- 80 people
- Sponsor
- AB Foundation
Leishmaniasis
Miltefosine (Long Course) for Bolivian Mucosal Leishmaniasis
Miltefosine (longer course) will be used to try to improve the cure rate of mucosal leishmaniasis
- Trial name
- NCT00373568
- Testing
- miltefosine: 2.5 mg/kg/day for 42 days
- Where
- Bolivia
- Volunteers
- 25 people
- Sponsor
- AB Foundation
Diarrhea, Rotavirus Infection
Probiotics in the Management of Acute Rotavirus Diarrhea in Bolivian Children
The purpose of this study is to determine the effect of probiotics in rotavirus acute diarrhea in children. The investigators will compare the effect of two different probiotics products.
- Trial name
- NCT00981877
- Testing
- GB (Florestor), GRALB
- Where
- Bolivia
- Volunteers
- 76 people
- Sponsor
- Centro Pediatrico Albina de Patino
Diarrhea, Rotavirus Infection
Use of Nitazoxanide and Probiotics in Acute Diarrhea Secondary to Rotavirus
Nitazoxanide has proved an cytoprotective effect against rotavirus infection. How it could be clinically important in time of hospitalization and reduction of duration of diarrhea secondary to rotavirus?
- Trial name
- NCT00683982
- Testing
- Nitazoxanide, Probiotic mix preparation, Oral hydration solutions
- Where
- Bolivia
- Volunteers
- 75 people
- Sponsor
- Centro Pediatrico Albina de Patino
Cutaneous Leihmaniasis
Short Course of Miltefosine and Antimony to Treat Cutaneous Leishmaniasis in Bolivia
The combination of a half-course of miltefosine and a half-course of antimony will be evaluated for efficacy and tolerance. The combination of miltefosine and antimony is chosen because these are now the two standard agents in…
- Trial name
- NCT00537953
- Testing
- Miltefosine , meglumine antimoniate
- Where
- Bolivia
- Sponsor
- Centro de Investigaciones Bioclínicas de la Fundación Fader
Women's Health
Efficacy of the Standard Days Method of Family Planning
The Standard Days Method® is a fertility awareness-based method of family planning in which users avoid unprotected intercourse during cycle day 8 through 19.
- Trial name
- NCT00505609
- Testing
- Standard Days Method
- Where
- 3 sites in Bolivia, Peru and 1 more
- Volunteers
- 478 people
- Sponsor
- Georgetown University
Tuberculosis
Multicenter Trial for the Evaluation of a Fixed Dose Combined Tablet for the Treatment of Pulmonary Tuberculosis
The use of fixed-dose combined (FDC) drugs in the treatment of tuberculosis by National Tuberculosis Programmes has been recommended by both the International Union Against Tuberculosis and Lung Disease (The Union) and the World…
- Trial name
- NCT00216333
- Testing
- combined fixed dose combination
- Where
- 9 sites in Algeria, Bolivia and 7 more
- Volunteers
- 1,500 people
- Sponsor
- International Union Against Tuberculosis and Lung Diseases
Leishmaniasis
Miltefosine for Mucosal Leishmaniasis
This trial will study miltefosine as a treatment for mucosal leishmaniasis.
- Trial name
- NCT00373776
- Testing
- miltefosine 2.5 mg/kg/day for 28 days
- Where
- Bolivia
- Volunteers
- 75 people
- Sponsor
- AB Foundation