Clinical trials: completed, in Cameroon
HIV-1 and HSV-2 Coinfection, HIV Infections
Usage of Acyclovir for Suppression of HIV-1 and HSV-2 Coinfected Persons in Cameroon
The study proposed that both clinical and subclinical HSV reactivation is associated with increased HIV shedding from mucosal surfaces, which may increase the infectiousness of HIV-1/HSV-2 coinfected persons.
- Trial name
- NCT00209313
- Testing
- Acyclovir
- Where
- Cameroon
- Volunteers
- 40 people
- Sponsor
- Fred Hutchinson Cancer Center
Adherence, HIV
Cameroon Mobile Phone SMS Trial
The investigators hypothesize that sending weekly motivational text messages to people infected with HIV will encourage them to take their medication, compared to usual care.
- Trial name
- CAMPS (NCT01247181)
- Testing
- Mobile phone text message, Usual care
- Where
- Cameroon
- Volunteers
- 200 people
- Sponsor
- Yaounde Central Hospital
Infections With Soil-Transmitted Helminths (STH)
A Multinational Trial of the Efficacy of Albendazole Against Soil-transmitted Nematode Infections in Children
The three major Soil-Transmitted Helminths (STH), Ascaris lumbricoides, Necator americanus/Ancylostoma duodenal and Trichuris trichiura are among the most prevalent parasites worldwide.
- Trial name
- WORMCON (NCT01087099)
- Testing
- Albendazole
- Where
- 7 sites in Brazil, Cambodia and 5 more
- Volunteers
- 1,750 people
- Sponsor
- University Ghent
Insulin Resistance, HIV/AIDS
The Effects of Spirulina Platensis on Insulin Resistance in HIV-infected Patients
Spirulina, a widely used food supplement, improves the lipid profile and glycemic control in people living with diabetes, suggesting that it could have some effects on insulin sensitivity.
- Trial name
- NCT01141777
- Testing
- Spirulina platensis, Soya bean
- Where
- Cameroon
- Volunteers
- 33 people
- Sponsor
- Yaounde Central Hospital
Diabetes, Arterial Hypertension
Treat Arterial Hypertension and Diabetes in Rural Africa
The purpose of this study is to determine the efficacy of three different interventions to improve treatment adherence among patients with arterial hypertension or diabetes in rural Cameroon.
- Trial name
- TAHADIRA (NCT00744458)
- Testing
- Treatment contract, Tracing and recall at home by a community worker, Incentive
- Where
- Cameroon
- Volunteers
- 223 people
- Sponsor
- Cooperation Afrique
Obesity, Hyperlipidemia
Lepticore in Metabolic Syndrome and Weight Loss
Metabolic syndrome is directly related to obesity. This study investigated the use of a plant based formulation to improve on the condition of people with metabolic syndrome.
- Conditions
- Obesity, Hyperlipidemia, Hyperglycemia
- Trial name
- NCT01046968
- Testing
- Lepticore
- Where
- Cameroon
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Yaounde 1
Malaria
Safety and Efficacy Study of Artesunate and Mefloquin in Children With Uncomplicated Malaria
The present study aims to investigate and to assess possible neurological and neuropsychiatric events in young children in west Africa with uncomplicated P.
- Trial name
- NCT00978172
- Testing
- artesunate and mefloquine
- Where
- Cameroon
- Volunteers
- 220 people
- Sponsor
- Mepha Ltd.
Malaria
ATAQ EASY: Artesunate + Amodiaquine Fixed Dose Combination in the Treatment of Uncomplicated Plasmodium Falciparum Malaria
Primary Objective: To demonstrate the non-inferiority, in terms of clinical and parasitological efficacy on D28 of administration of Coarsucam™ (artesunate+amodiaquine fixed-dose combination), as a single daily dose, in…
- Trial name
- NCT00316329
- Testing
- Artesunate + Amodiaquine
- Where
- 5 sites in Cameroon, Madagascar and 2 more
- Volunteers
- 1,032 people
- Sponsor
- Sanofi
Malaria
Arsucam® (Artesunate + Amiodaquine) Efficacy and TOLerance
Primary Objective: To demonstrate the non-inferiority, in terms of clinical and parasitological efficacy on Day 14, of administration of Arsucam® as a single daily intake versus two daily intakes.
- Trial name
- ATOL (NCT00445796)
- Testing
- Artesunate, Amodiaquine
- Where
- 2 sites in Cameroon, Senegal
- Volunteers
- 300 people
- Sponsor
- Sanofi
Metabolic Syndrome, Obesity
Effect of Irvingia Gabonensis (Bush Mango)on Parameters Associated With Metabolic Syndrome
The study investigated the use and efficacy of the seeds of African bush mango (Irvingia gabonensis)to control body weight, blood lipids and hormones in overweight and obese people.
- Conditions
- Metabolic Syndrome, Obesity, Dyslipidemia
- Trial name
- NCT00645775
- Testing
- IGOB131
- Where
- Cameroon
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Gateway Health Alliance
Plasmodium Falciparum Malaria
Multi-Centre Trial Comparing Three Artemisinin-Based Combination Treatments on P. Falciparum Malaria
The purpose of this open randomised multi-centre clinical trial is to test the hypothesis that three pills of the fixed dose combination artesunate/sulfamethoxypyrazine/pyrimethamine, administered over 24 hours is not inferior in…
- Trial name
- NCT00484900
- Testing
- Co-Arinate FDC, Coartem
- Where
- 4 sites in Cameroon, Mali and 2 more
- Volunteers
- 1,390 people
- Sponsor
- Dafra Pharma
HIV Infections, Sexually Transmitted Diseases
Safety, Tolerance and Acceptability Trial of the Invisible Condom® in Healthy Women
The objectives of this clinical study are to evaluate the extended safety, tolerance and acceptability of a vaginal gel formulation when applied in 452 healthy women volunteers.
- Trial name
- NCT00136643
- Testing
- Invisible Condom®
- Where
- Cameroon
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Laval University
HIV Infections, Hepatitis B
ProAlgaZyme Novel Algae Infusion: Applications in Immunodeficiency
The purpose of this study is to determine the safety and effects in HIV patients of supplementation (4-20 fl. oz. daily) with ProAlgaZyme, a novel fermentation product of a freshwater algae ecosystem, on markers of immune status…
- Conditions
- HIV Infections, Hepatitis B, Dyslipidemia
- Trial name
- NCT00493506
- Testing
- ProAlgaZyme
- Where
- Cameroon
- Volunteers
- 59 people
- Sponsor
- Health Enhancement Products, Inc.
Metabolic Syndrome X
ProAlgaZyme Novel Algae Infusion: Applications in Metabolic Syndrome
The purpose of this study is to compare the effects of supplementation with ProAlgaZyme (a novel fermentation product of a freshwater algae ecosystem) vs.
- Trial name
- NCT00489333
- Testing
- ProAlgaZyme
- Where
- Cameroon
- Volunteers
- 52 people
- Sponsor
- Health Enhancement Products, Inc.
HIV Infections
Study of Tenofovir Disoproxil Fumarate (TDF) for Prevention of HIV
This Phase 2 study involving tenofovir disoproxil fumarate (TDF) will assess the extended safety of TDF 300 mg per day among young women who are not HIV-infected.
- Trial name
- NCT00122486
- Testing
- Tenofovir Disoproxil Fumarate
- Where
- 3 sites in Cameroon, Ghana and 1 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- FHI 360