Clinical trials: in Colombia
Papillomavirus Infections
Efficacy Against Oral Persistent Infection, Immunogenicity and Safety of the 9-valent Human Papillomavirus Vaccine (9vHPV) in Men Aged 20-45 Years (V503-049)
The purpose of this study is to evaluate the efficacy, immunogenicity and safety of the 9vHPV vaccine in men 20 to 45 years of age.
- Trial name
- NCT04199689
- Testing
- 9vHPV Vaccine
- Where
- 103 sites in United States, Belgium and 14 more
- Volunteers
- 6,033 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Coronary Artery Stenosis
Breathing-Maneuver-Induced Myocardial Oxygenation Reserve Validated by FFR (B-MORE)
The study aims to determine a diagnostic marker for regionally impaired myocardial oxygenation response in patients with suspected coronary artery stenosis.
- Trial name
- B-MORE (NCT04126148)
- Where
- 8 sites in United States, Australia and 5 more
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Matthias Friedrich
Sports, Psychosocial
Brief Structured Team Reflection Embedded in Elite Underwater Rugby Training (BSTR-UWR)
This single-arm field evaluation examined whether a brief, structured team reflection routine embedded within usual elite underwater rugby training was associated with change in team cohesion, psychological safety, peer trust…
- Conditions
- Sports, Psychosocial, Cohesion, Social
- Trial name
- BSTR-UWR (NCT07448012)
- Testing
- Brief Structured Team Reflection (BSTR)
- Where
- Colombia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Édison Andrés Pérez Bedoya
Swimming Kinematics, Physical Fitness
Velocity-regulated Jump-squat Training and 15-m Swimming Start Performance in Youth Swimmers
This study aims to examine the effects of a structured swimming training intervention on sport performance-related outcomes in 14- to 15-year-old federated swimmers from Club Huracanes.
- Conditions
- Swimming Kinematics, Physical Fitness, Youth
- Trial name
- HUR-SWIM (NCT07571057)
- Testing
- Structured Swimming Training Intervention
- Where
- Colombia
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Federal University of Vicosa
Deficiencies Micronutrient, Nutrition Disorders
Effect of Consuming Vitamin A-fortified Sugar on Serum Retinol Levels in Children
The increase in vitamin A deficiency (<20 mcg/dL) among children under five in Colombia (2010-2015) is a public health problem (27.3%).
- Trial name
- NCT07860060
- Testing
- white sugar fortified with retinol, refined white sugar for culinary use
- Where
- Colombia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
HIV-1 Infection
DOR/ISL in HIV-1 Antiretroviral Treatment-naïve Participants (MK-8591A-053)
This is a randomized, active-controlled, double-blind clinical study designed to evaluate the antiretroviral activity, safety, and tolerability of doravirine/islatravir (DOR/ISL [MK-8591A]) in treatment-naïve participants with…
- Trial name
- NCT05705349
- Testing
- DOR/ISL, BIC/FTC/TAF
- Where
- 131 sites in United States, Argentina and 19 more
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Alzheimer's Disease
Dominantly Inherited Alzheimer Network (DIAN)
The purpose of this study is to identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.
- Trial name
- DIAN (NCT00869817)
- Where
- 26 sites in United States, Argentina and 11 more
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Wellbeing
Self-Help Plus Pilot Study, Colombia: Train2Care
This project will strengthen local capacity for mental health care in high-need settings in Colombia by culturally and linguistically adapting the Self-Help+ intervention and delivering participatory, supervised training.
- Trial name
- T2C (NCT07524309)
- Testing
- Self help plus
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- George Washington University
Respiratory Syncytial Virus
A Study to Evaluate the Safety and Efficacy of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) in Adults ≥60 Years of Age
The main purpose of Part A of this study is to evaluate the safety and tolerability of mRNA-1345 vaccine and to demonstrate the efficacy of a single dose of mRNA-1345 vaccine in the prevention of a first episode of RSV-associated…
- Trial name
- NCT05127434
- Testing
- mRNA-1345
- Where
- 269 sites in United States, Argentina and 21 more
- Volunteers
- 36,814 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Invasive Extraintestinal Pathogenic Escherichia Coli Disease (IED) Prevention
A Study of Vaccination With 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) in the Prevention of Invasive Extraintestinal Pathogenic Escherichia Coli Disease in Adults Aged 60 Years And Older With a History of Urinary Tract Infection in the Past 2 Years
The purpose of this study is to demonstrate the efficacy of 9-valent extraintestinal pathogenic Escherichia coli vaccine (ExPEC9V) compared to placebo in the prevention of the first invasive extraintestinal pathogenic Escherichia…
- Trial name
- NCT04899336
- Testing
- ExPEC9V
- Where
- 374 sites in United States, Australia and 19 more
- Volunteers
- 17,797 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Human Immunodeficiency Virus (HIV), HIV Pre-Exposure Prophylaxis
A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
Researchers are looking for new medicines to prevent HIV-1 (Human Immunodeficiency Virus Type 1) infection. The goals of this study are to learn: If taking MK-8527 once a month works to prevent HIV-1 infection as well as or…
- Trial name
- NCT07044297
- Testing
- MK-8527, FTC/TDF
- Where
- 81 sites in United States, Argentina and 14 more
- Volunteers
- 4,390 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Tactical Index, Sport
TPCT Underwater Rugby Women
This randomized controlled trial evaluates whether adding a short, structured team-reflection protocol (Tactical Programme for Critical Thinking, TPCT) to regular elite women's underwater rugby training improves tactical…
- Conditions
- Tactical Index, Sport, Sport Participation, Teamwork
- Trial name
- TPCT-UWRW (NCT07458581)
- Testing
- Matched Tactical Training Programme (MTT), Tactical Programme for Critical Thinking (TPCT) - Structured Reflective Questioning
- Where
- Colombia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Édison Andrés Pérez Bedoya
Motivation
Peer-Mentoring and Motivational Regulation in Colombian Youth Swimmers
This completed study examined whether young competitive swimmers' reasons for participating in sport changed after a peer-mentoring programme.
- Trial name
- NCT07769541
- Testing
- Eight-Session Peer-Mentoring Programme
- Where
- Colombia
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Édison Andrés Pérez Bedoya
Obesity
Ultraprocessed Foods in Colombia
The study seeks to examine how characters on packaging and warning labels affect purchase intentions and risk perception among children aged 12 to 17 in Colombia and, examine whether characters' presence weakens or reduces the…
- Trial name
- NCT07528443
- Testing
- Warning label, Barcode control label, Character
- Where
- Colombia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Autosomal Dominant Alzheimers Disease, Early Onset Alzheimer Disease
A Study of Donanemab, RG6289, or the Combination of Donanemab and RG6289 in Presenilin 1 (PSEN1) E280A Mutation Carriers for the Treatment of Autosomal-Dominant Alzheimer's Disease
The study will be conducted in 2 blinded parts (Part 1 and Part 2). In Part 1, study participants who are mutation carriers will receive active donanemab and non-mutation carriers will receive placebo-donanemab for up to 18…
- Conditions
- Autosomal Dominant Alzheimers Disease, Early Onset Alzheimer Disease, Alzheimers Disease
- Trial name
- NCT06996730
- Testing
- Donanemab, RG6289
- Where
- Colombia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Banner Health
Athletic Performance, Decision Making
Critical Thinking Tactical Training in University Futsal Players
This study examined the effects of a tactical training program based on critical thinking (TPCT) on the tactical efficiency and decision-making performance of university futsal players.
- Trial name
- TPCT-FUTSAL (NCT07279753)
- Testing
- Tactical Program Critical Thinking
- Where
- Colombia
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Federal University of Vicosa
Mental Health, Physical Activity
Classroom Exercise Frequency and Mental Health in Medical Students
This 16-week, three-group, nonrandomized interventional study evaluated whether the weekly frequency of a brief classroom-based physical exercise program was associated with changes in mental health and physical activity among…
- Trial name
- NCT07756879
- Testing
- Brief Classroom-Based Physical Exercise Program
- Where
- Colombia
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Dynamical Business and Science Society - DBSS International SAS
Pneumonia, Radiography
Change in the Proportion of Correct Interpretations of Pulmonary Opacities
This randomized crossover clinical trial will evaluate whether an artificial intelligence-based expert system improves the interpretation of chest radiographs by final-year medical students, rural physicians, and general…
- Trial name
- INTERPRET (NCT07744555)
- Testing
- Artificial intelligence expert system
- Where
- Colombia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de la Sabana
Pain, Pain Intervention
Impact on Patients With Neuromuscular and Musculoskeletal Conditions Associated With Benign Chronic Pain Using Atlas Profilapxis
AtlasPROfilax®is a method performed in 2 authorized centers in Colombia focused on patients with chronic non-malignant pain. The study seeks to see the effectiveness of the method in different pathologies through a randomized…
- Trial name
- Atlasprofilax (NCT07745088)
- Testing
- Atlasprofilax Therapy
- Where
- Colombia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fundacion Nacional Somos
Neoplasms, Solid Tumor
Methylation Profile Test (Methylscape) in Body Fluids for Multi-Cancer Detection and Monitoring in Colombia
DNA methylation changes occur early and broadly during carcinogenesis. Methylscape is a rapid assay that detects global DNA methylation patterns in body fluids (blood, urine, and saliva) and may detect a cancer signal and predict…
- Conditions
- Neoplasms, Solid Tumor, Breast Neoplasms, Lung Neoplasms
- Trial name
- METHYLSCAPE-CO (NCT07741435)
- Testing
- Methylscape DNA methylation assay
- Where
- Colombia
- Volunteers
- 3,250 people, healthy volunteers welcome
- Sponsor
- Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo