Clinical trials: in Egypt
Septoplasty Surgeries
Cold Dissection vs Electrocautry on TCR in Septoplasty
This study aims to address these gaps by comparing the incidence of TCR during septoplasty performed using cold dissection versus electrocautery, while also incorporating a novel assessment of surgical force.
- Trial name
- TCR (NCT07425834)
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fatmaelzahraa Omar Mahmoud Bahr
Renal Stone
Comparison Between External Oblique Intercostal Block and Erector Spinae Plane Block in PCNL
The aim of the study is to compare the post-operative analgesic effect of USG unilateral External oblique intercostal (EOI) block with Erector spinae plane block (ESPB) for after percutaneous Nephrolithotomy with a hypothesis…
- Trial name
- NCT06131151
- Testing
- External Oblique Intercostal Block, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University
CHD - Congenital Heart Disease
Bilateral Ultrasound Guided Superficial Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block
Group (A): This group will receive fentanyl infusion at a dose of (0.5μg/kg/h) all through the whole operation plus ultrasound guided bilateral superficial parasternal intercostal Plane block which will be done by injecting…
- Trial name
- NCT06958120
- Testing
- superficial parasternal intercostal Plane block, Erecto spinea plane block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
HCC - Hepatocellular Carcinoma
Real-world Insight Into Systemic Therapies for HCC: Single-center Study
Real-world data from a single-center experience evaluating patients with hepatocellular carcinoma (HCC) receiving systemic therapies
- Trial name
- HCC (NCT07814014)
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- Mansoura University
Bacterial Keratitis, Recalcitrant Infectious Keratitis
Intrastromal Moxifloxacin as an Adjunctive Therapy in Recalcitrant Bacterial Keratitis
Bacterial keratitis is a potentially sight-threatening corneal infection that is commonly treated with intensive topical antibiotics.
- Conditions
- Bacterial Keratitis, Recalcitrant Infectious Keratitis, Corneal Ulcer
- Trial name
- NCT07394257
- Testing
- Intrastromal moxifloxacin injection plus standard topical moxifloxacin therapy, Standard topical moxifloxacin therapy alone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Sleep Apnea Syndromes
f Adding Ketamine to Propofol For Drug-induced Sleep Endoscopy in Adult Patients With Obstructive Sleep Apnea
The investigator compared the sedative effects of propofol alone and ketamine added to propofol in drug induced sleep endoscopy
- Trial name
- NCT04452383
- Testing
- Ketamine + propofol, propofol
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Zagazig University
Striae Rubra
Evaluating the Effectiveness and Safety of Microneedling With Topical Tranexamic Acid in Treatment of Striae Rubra
This study aims to evaluate the efficacy and safety of microneedling with topical tranexamic acid versus microneedling with placebo (normal saline) in the treatment of striae rubra.
- Trial name
- NCT07795515
- Testing
- Topical tranexamic acid, normal saline (0.9% NaCl)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Bariatric Sleeve Gastrectomy
Impact of Asprosin and Neuregulin 4 on Metabolic Parameters, Anthropometric Indices and Body Composition After Laparoscopic Sleeve Gastrectomy
Asprosin and neuregulin 4 (NRG4) sit on opposing arms of adipose endocrine physiology. Asprosin is a fasting-induced, white adipose-derived glucogenic and orexigenic hormone that rises with adiposity and insulin resistance.
- Trial name
- NCT07806448
- Testing
- sleeve gastrectomy
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Skeletal Muscle, Bariatric Surgery
Circulating Muscle-specific microRNAs and Renal, Nutritional and Inflammatory Biomarkers of Skeletal Muscle Loss During the First 18 Months After Laparoscopic Sleeve Gastrectomy
Metabolic and bariatric surgery produces substantial and durable weight loss, but a considerable proportion of that loss is not adipose tissue.
- Trial name
- NCT07806513
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Periodontal Diseases
Locally Delivered Melatonin Gel in Management of Stage II Grade B Periodontitis
Background: Periodontitis is a chronic inflammatory disease characterized by the destruction of tooth-supporting tissues, driven by an imbalance between bacterial pathogens and the host immune response.
- Trial name
- NCT07813936
- Testing
- 2% Melatonin gel
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Alexandria University
Gingival Hyperpigmentation
Licorice Extract Gel Versus Diode Laser for Physiologic Gingival Pigmentation
This randomized controlled clinical trial aims to compare the effectiveness of topical licorice extract gel and diode laser (445 nm) in the treatment of physiologic gingival pigmentation.
- Trial name
- NCT07325825
- Testing
- Diode Laser 445 nm, Licorice Extract Gel
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Neonatal Hyperbilirubinemia
Efficacy & Safety of Oral Adjuvants to Phototherapy in Neonatal Hyperbilirubinemia
Neonatal jaundice, or neonatal hyperbilirubinemia, is a common medical issue in the first two weeks of life, causing prolonged hospitalization and readmissions.
- Trial name
- NCT06517862
- Testing
- Zinc sulfate, Ursodeoxycholic acid
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Amira Adel Fouly
Truness of Impression Techniques in All on x Cases, Trueness of Full Arch Implant Prosthesis Impression
Truness of Full Arch Impressions in All on x Cases
This study aims to compare the trueness and precision of three impression methodologies photogrammetry, digital intraoral scanning with splinted scan bodies, and conventional open tray impressions in the context of the All-on-X…
- Trial name
- NCT07550725
- Testing
- photogrammetry based full arch impression, Digital Impression Using Splinted Scan Bodies, Conventional Open-Tray Implant Impression
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- October 6 University
Type 2 Diabetes
Adding SGLt2 Inhibitors to Patients With Type 2 Diabetes
To detect the efficacy of SGLT2i in improving the metabolic parameters in patients with type 2 diabetes. To detect the side-effects of SGLT2i
- Trial name
- NCT06268977
- Testing
- SGLT2 inhibitor
- Where
- Egypt
- Volunteers
- 482 people
- Sponsor
- Assiut University
Pre-Eclampsia, Preeclampsia
Internal Jugular Vein Collapsibility Index for Volume Status Assessment in Preeclampsia in Correlation With Normotensive Parturients
This study aims to assess and analyze volume status in preeclamptic patients and compare these parameters with those of normotensive pregnant ones based on the change in internal jugular vein ultrasound-based indices.
- Trial name
- NCT07786246
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tanta University
Physiological Gingival Pigmentation
Laser Treatment With Methylene Blue vs. Nanoparticle-Assisted Photodynamic Therapy for Gingival Pigmentation: A Randomized Clinical Trial
This prospective, randomized, controlled, single-blinded, three-arm clinical trial compared the clinical effectiveness of conventional methylene blue-mediated photodynamic therapy (MB-PDT) and methylene blue nanoparticle-mediated…
- Trial name
- MB-Laser-GP (NCT06834087)
- Testing
- Laser-Assisted Gingival Depigmentation, Drug: Conventional Methylene Blue-Mediated Photodynamic Therapy, Drug: Methylene Blue Nanoparticle-Mediated Photodynamic Therapy
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Roaa Hadi Hussein Jasem
Cross-cultural Adaptation, Validity
Cross-Cultural Adaptation, Validity and Reliability Test of the Arabic Version of the Maine-Seattle Back Questionnaire
The purpose of this study is to translate and test face validity, content validity, construct validity, internal consistency reliability, and test-retest reliability of adapted Arabic-language version of MSBQ in patients with low…
- Conditions
- Cross-cultural Adaptation, Validity, Reliability
- Trial name
- NCT07811414
- Testing
- No intervention
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
GERD
Endoscopic Band Ligation for Treating Reflux Disease
GERD is a chronic disease the require different treatment modalities; non have proven long term efficacy with concerns about their safety. The use of band ligation in endoscopy appears safe, repeatable with short learning curve.
- Trial name
- NCT06126055
- Testing
- Band Ligation
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- El Katib Hospital
Cesarean Section
Health Education to Reduce Unnecessary Cesarean Section Among Primigravida Women
This study aims to evaluate the Effectiveness of Health Educational Program for Primigravida Women in Reducing the Rate of Unnecessary Cesarean Section. Specific objectives: 1.
- Trial name
- CS (NCT07810751)
- Testing
- Health Educational Program on Modes of Delivery.
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Neonatal Respiratory Distress, Lung Ultrasound Score
Predictive Value of Lung Ultrasound Combined With Serum ANGPL4 Levels for NICU Admission Needs in Late Preterm and Term Neonates With Respiratory Distress In The Transion Period
The aim of this study is to evaluate the validity of point-of-care lung ultrasound (POC-LUS) and serum ANGPL4 levels for predicting NICU admission needs in late preterm and full-term neonates with respiratory distress shortly…
- Trial name
- NCT07809971
- Testing
- Point of care lung ultrasound (POC-LUS), Serum ANGPTL4
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
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