Clinical trials: in Egypt
Knee Arthroscopic Surgery, Nerve Block
TIPS Block vs. IV Analgesia for Postoperative Pain After Knee Arthroscopy
In this study participants are aiming to compare triple injection peri-sartorius (TIPS) block versus intravenous analgesia for postoperative analgesia after knee arthroscopy regarding efficacy of pain relief and early ambulation
- Trial name
- NCT07046390
- Testing
- nerve block with bupivacaine 0.25%, No intervention
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Viral Lung Infection and Acute Respiratory Failure
Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
The purpose of this study is to evaluate the effect of tozorakimab, as an add-on to SoC in patients with viral lung infection requiring supplemental oxygen, on the prevention of death or progression to IMV/ECMO.
- Trial name
- TILIA (NCT05624450)
- Testing
- Tozorakimab
- Where
- 473 sites in United States, Argentina and 37 more
- Volunteers
- 3,527 people
- Sponsor
- AstraZeneca
Inflammatory Bowel Diseases
Atorvastatin in Patients With Ulcerative Colitis
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease characterized by diffused inflammation of the colon and rectum mucosa; however, the exact underlying mechanisms of UC remain poorly understood.
- Trial name
- NCT05561062
- Testing
- Atorvastatin 80mg
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Iron Deficiency Anemia (IDA), ESRD (End Stage Renal Disease)
Management of Iron Deficiency Anemia in Hemodialysis Patients
The aim of this interventional study is to assess the effectiveness of oral lactoferrin in improving hemoglobin levels and correcting iron deficiency anemia in patients with end-stage renal disease (ESRD) on dialysis and also…
- Trial name
- NCT07706582
- Testing
- Lactoferrin, IV iron sucrose
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Beni-Suef University
Anaemia, Chronic Kidney Disease
Probiotics Against Erythropoietin Resistance in Chronic Kidney Disease Patients.
The goal of this clinical trial is to assess whether probiotic supplementation can improve the hematological response of CKD patients to erythropoietin therapy and prevent or reduce erythropoietin resistance.
- Conditions
- Anaemia, Chronic Kidney Disease, Regular Hemodialysis
- Trial name
- NCT07296146
- Testing
- Erythropoietin + Probiotic, EPO
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Badr University
Parkinson Disease
Clinical Study to Evaluate the Possible Efficacy of Metformin in Patients With Parkinson's Disease
Parkinson's disease (PD) is one of the most common neurodegenerative diseases characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra compacta (SNc) and aggregation of Lewy bodies in neurons.
- Trial name
- NCT05781711
- Testing
- levodopa-carbidopa, Metformin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Dermatologic Disease
A Comparative Clinical Trial Evaluating the Effect and Safety of Tacrolimus Versus Hydrocortisone
One of the most frequent skin conditions is atopic dermatitis (AD), characterized by its pruritic inflammation effect. Where the prevalence of AD increased in the last three decades by two or three folds worldwide, especially in…
- Trial name
- NCT05607901
- Testing
- Tacrolimus ointment, Hydrocortisone 1% cream
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Stress
Stress Modulation and Dynamic Balance
This three-arm, parallel-group, randomized controlled trial (RCT) investigates whether dual-task therapeutic exercises (dynamic balance + cognitive task) improve perceived stress and dynamic balance in 72 healthy university…
- Trial name
- NCT07571369
- Testing
- Dynamic balance exercises, Control group, Dual task exercises
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Scleroderma
Cross-cultural Adaptation and Validation of the Localised Scleroderma Quality of Life Instrument (LoSQI) in Juvenile Localised Scleroderma (JLS)
This international study adapts and validates the Localised Scleroderma Quality of Life Instrument (LoSQI) for children with JLS, a rare condition causing hardened skin and tissue.
- Trial name
- LoSQI (NCT07908108)
- Where
- 33 sites in Argentina, Brazil and 17 more
- Volunteers
- 272 people
- Sponsor
- Istituto Giannina Gaslini
Menstrual Cycle
Dynamic Knee Stability in Middle Aged Women Through Different Phases of Menstrual Cycle
The purpose of the study was to provide a data base about knee functional stability in normal adult female and to clarify the effect of monthly hormonal fluctuations during phases of normal female menstrual cycle on functional…
- Trial name
- NCT07907471
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hemiplegic Cerebral Palsy
EFFECT OF ROBOTIC GLOVES TRAINING ON UPPER LIMB COORDINATION, SELECTIVE MOTOR CONTROL AND ACTIVITIES OF DAILY LIVING IN CHILDREN WITH HEMIPARETIC CEREBRAL PALSY.
The purposes of the current study will be to assess the effect of robotic gloves training on upper limb coordination, selective motor control (Wrist Extension/Flexion, Finger Flexion/Extension, Thumb Opposition (tip to tip…
- Trial name
- UL/SMC/ADL/CP (NCT07907497)
- Testing
- Robotic Glove Therapy, Occupational Therapy Group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Post Herpetic Neuralgia (PHN)
Transcutaneous Auricular Vagus Nerve Stimulation on Post-Herpetic Neuralgia
The purpose of this study is to evaluate the therapeutic efficacy of transcutaneous auricular vagus nerve stimulation (taVNS) in the treatment of patients with post-herpetic neuralgia (PHN).
- Trial name
- NCT07123987
- Testing
- transcutaneous auricular vagus nerve stimulation (taVNS), traditional medical treatment for PHN
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Mohamed Hosny Ismail Easa
Breast Feeding, Maternal and Infant Bonding
Empowering First-Time Mothers
This randomized controlled trial aims to evaluate the effect of digital lactation nursing support on breastfeeding achievement and maternal-infant outcomes among first-time mothers.
- Trial name
- Empowering (NCT07900932)
- Testing
- digital lactation nursing support program
- Where
- 2 sites in Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tanta University
Normal Labor
Generative AI-Powered Intrapartum Clinical Decision Support Among Healthcare Providers
Pregnancy and childbirth are uniquely important events in women's lives because they are accompanied by major physical, emotional, and psychological changes.
- Trial name
- Smart labor (NCT07720531)
- Testing
- The intervention group
- Where
- Egypt
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Voice, Therapy
Voice Therapy in Reactive Benign Vocal Fold Polyp and Injection of Steroid
The aim of this study is to compare the efficacy between Voice Therapy and Injection of Steroid in Reactive Benign Vocal Fold polyp.
- Conditions
- Voice, Therapy, Vocal Fold Polyp, Steroid Injection
- Trial name
- NCT07904988
- Testing
- Group 1: Patients with reactive benign vocal fold polyp will be treated by Voice Therapy, Group 2: Patients with reactive benign vocal fold polyp will be treated by Injection of steroid
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Irreversible Pulpitis, Apical Periodontitis
Effect of Different Methods of Cryotherapy Applications on Postoperative Pain and Substance P Level in Patients With Acute Irreversible Pulpitis With Apical Periodontitis: A Randomized Controlled Trial
This randomized controlled clinical trial evaluates the effect of different methods of cryotherapy (extra-oral, intra-canal, and combination) on postoperative pain and periapical Substance P levels in patients with acute…
- Trial name
- NCT07904312
- Testing
- Extra-oral Cryotherapy, Intra-canal Cryotherapy, Combination (extra-oral and intra-canal)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ahmad badrah
Developmental Dysplasia of the Hip, Acetabular Bone Loss
3D-Printed Pelvic Models for Planning Complex Total Hip Arthroplasty
Total hip arthroplasty (THA) in patients with complex acetabular anatomy can be challenging because of abnormal bone structure, deformity, or bone loss.
- Conditions
- Developmental Dysplasia of the Hip, Acetabular Bone Loss, Acetabular Fracture
- Trial name
- NCT07904637
- Testing
- Conventional Imaging-Based Preoperative Planning, CT-Based 3D-Printed Pelvic Model-Assisted Planning
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Ain Shams University
Dental Caries in Children
Evaluation of the Antibacterial Effect of Probiotics on Cariogenic Bacteria in Children
This randomized controlled clinical trial aims to evaluate the effect of oral probiotic lozenges containing Streptococcus salivarius, Lactobacillus reuteri, and Lactobacillus paracasei on cariogenic bacteria (Streptococcus…
- Trial name
- NCT07904221
- Testing
- Probiotic lozenges containing Streptococcus salivarius, Lactobacillus reuteri, and Lactobacillus paracasei, Xylitol-based moisturizing lozenges
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Therapeutic Communication
Culturally-Tailored AI Chatbot Simulation for Therapeutic Communication and Empathy in Psychiatric Nursing Students
Therapeutic communication and empathy are core competencies in psychiatric nursing, yet students often have limited opportunities to practise them safely with culturally realistic patients and families.
- Trial name
- AI-CHAT-PSY (NCT07905469)
- Testing
- Culturally-Tailored AI Chatbot Simulation, Instructor-Facilitated Peer Role-Play
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Cervical Radiculopathy
Myo-Electrical and Nerve Root Function Response to Focused Extracorpeal Shock Wave in Cervical Radiculopathy
BACKGROUND: Upper limb nerve root dysfunction with increased active myofascial trigger point in upper trapezius is common problem in patients with cervical radiculopathy.
- Trial name
- NCT06102304
- Testing
- Focused Extracorpeal Shock wave
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University