Clinical trials: suspended, in France
Alzheimer Disease
A Study of Sodium Oligomannate (GV-971) in Participants With Mild to Moderate Alzheimer's Disease
The purpose of this study is to evaluate the safety, tolerability and efficacy of GV-971 in mild to moderate Alzheimer's disease.
- Trial name
- GREEN MEMORY (NCT04520412)
- Testing
- GV-971
- Where
- 171 sites in United States, Australia and 8 more
- Volunteers
- 2,046 people
- Sponsor
- Green Valley (Shanghai) Pharmaceuticals Co., Ltd.
Schizophrenia, Episodic Memory Deficits
Retrieval Practice and Schizophrenia
When people are tested on a previously learned material, they will later remember it better even when compared to a condition where they can re-study it.
- Trial name
- NCT02108899
- Testing
- Retrieval practice effect using descriptive stories and free-call tests without feedback
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Pain, Postoperative
Study Comparing Two Methods of TransversusAbdominis Plane
Interventional, randomised, prospective, multicentric study
- Trial name
- CHIRTAP (NCT04108221)
- Testing
- laparoscopy or laparotomy withTransversusAbdominis Plane Block
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Institut Jean-Godinot
Pregnancy, Unwanted
Factors Associated With the Absence of Contraception at Women Seeking a Voluntary Termination of Pregnancy
The study will be offered to all women who are consultant for an abortion plan are seen in consultation at the orthogeny center where the study will be conducted.
- Trial name
- NCT04830007
- Where
- France
- Volunteers
- 560 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Parkinson Disease
A Training of the Rhythmic Skills With a Serious Game to Improve Gait and Cognitive Abilities in Parkinson's Disease
This project aims at assessing the opposite relation, namely the effect of a training of the general timing abilities on gait in Parkinson's disease. Timing rehabilitation will be done by the means of a serious game.
- Trial name
- RGP (NCT02855710)
- Testing
- Rhythm workers training Perceptive timing, Rhythm workers training sensorimotor timing, No Rhythm workers training
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Atherosclerosis of Artery
PROGENitors, TELomeres and ARTerial Aging
The prevailing view in telomere epidemiology is that leukocyte telomere length (LTL) is associated with atherosclerotic cardiovascular disease (ACVD) since it serves as a biomarker of the cumulative burden of inflammation and…
- Trial name
- PROGENTELART (NCT03928769)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Acute-On-Chronic Liver Failure
TRimetazidine for acUte on Chronic Liver Failure STudy
The study will assess the pharmacokinetics (PK), tolerability, and safety of oral trimetazidine administered to subjects with AD (ACLF Grade 0) or with ACLF Grade 1 or 2.
- Trial name
- TRUST (NCT03737448)
- Testing
- Trimetazidine
- Where
- 24 sites in Austria, Belgium and 3 more
- Volunteers
- 30 people
- Sponsor
- Martin Pharmaceuticals
COVID19, SARS-CoV-2 Infection
Study of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients: Sarilumab, Azithromycin, Hydroxychloroquine Trial - CORIMUNO-19 - VIRO
The overall objective of the study is to determine the therapeutic effect and tolerance of Sarilumab in combination with Azithromycin and Hydroxychloroquine, compared to Sarilumab only, patients with moderate, severe pneumonia…
- Trial name
- CORIMUNO-VIRO (NCT04341870)
- Testing
- Sarilumab, Azithromycin, Hydroxychloroquine
- Where
- 5 sites in France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility
Uterine Allotransplantations Using Uterine Grafts From Brain-dead Female Donors
Uterus transplantation may enable women with uterine factor infertility to become pregnant and give birth. This study will explore the feasibility of a uterine transplant and eight subjects will undergo deceased donor uterine…
- Trial name
- ATU (NCT02637674)
- Testing
- Uterus Transplant
- Where
- 4 sites in France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Limoges
Ovarian Cancer
Pelvic and Aortic-cava Lymphadenectomy Randomized for Ovarian Cancer
It is a multicenter randomized trial of superior cleaning compared the absence of dissection in stage III patients with optimal surgical resection without retroperitoneal lymph node palpable.
- Trial name
- CARACO (NCT01218490)
- Testing
- ovarian cancer surgery
- Where
- 19 sites in France
- Volunteers
- 450 people
- Sponsor
- Institut Cancerologie de l'Ouest
GERD, Gastro Esophageal Reflux
Endoscopic Resection in Gastro-Esophageal Reflux Disease
Currently patients with gastroesophageal reflux disease (GERD) are treated with proton pump inhibitors (PPIs). This long-term PPI treatment would likely increase the risk of pulmonary and digestive infections and would not…
- Trial name
- RESECT-RGO (NCT03357809)
- Testing
- Endoscopic mucosal resection
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Cirrhosis
Impact on Morbidity and Mortality of Prophylactic Dosing of Low Molecular Heparin in Child-Pugh B Cirrhotic Patients
Thrombosis occurring in the small intrahepatic, as well as in the large vessels is involved in the progression of cirrhosis. Anticoagulation could reduce morbidity and mortality in cirrhotic patients
- Trial name
- Childbenox (NCT02271295)
- Testing
- Enoxaparine
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Uveitis
Treatment of the Bilateral Severe Uveitis by IVT of Regulator T-cells: Study of Tolerance of Dose
Uveitis is a leading cause of blindness in the children and young adult's populations. One third of etiology are idiopathic. The reference treatments are corticosteroids and immunosuppressive agents.
- Trial name
- UVEREG (NCT02494492)
- Testing
- intravitreous administration of regulator T-cells
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chondrosarcoma
A Phase II Study of EVEROLIMUS in Patients With Primary or Relapsed Chondrosarcomas
The mainstay of chondrosarcoma treatment is a wide surgical resection. Unfortunately, this is a rare occurrence, and patients with incomplete resection have very poor therapeutic options.
- Trial name
- CHONRAD (NCT02008019)
- Testing
- Everolimus 2.5 mg/day, Everolimus 10 mg/day
- Where
- 12 sites in France
- Volunteers
- 57 people
- Sponsor
- Centre Leon Berard
Fecal Incontinence, Anal Incontinence
Medical and Economic Evaluation of a Magnetic Anal Sphincter for Patients With Severe Anal Incontinence
The purpose of this study is to compare 2 surgical treatments of severe fecal incontinence (defined as more than a major leak per week).
- Trial name
- MOS STIC (NCT01920607)
- Testing
- magnetic anal sphincter, sacral nerve stimulation
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Nantes University Hospital
Coronary Disease, Heart Transplant
Mesenchymal Stem Cell Administration in the Treatment of Coronary Graft Disease in Heart Transplant Patients
MES-HT is a pilot multicenter prospective study conducted in transplant patients who developed severe coronary vasculopathy. A preparation of autologous mesenchymal cells of bone marrow is administered by endomyocardial…
- Trial name
- MESHT (NCT02472002)
- Testing
- Mesenchymal cell therapy
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hepatitis B Virus Infection; Pregnant Women
Validity of Elastography During Pregnancy
Non invasive methods are the only available methods to stage liver fibrosis during pregnancy. The safety of elastometry - ultrasound based - is obvious, as medical supervision of pregnancy is based on ultrasonography, both…
- Trial name
- NCT02391467
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Hopital Lariboisière
Pain
Procedures of Locoregional Analgesia and Quality of Life in Palliative Care Units
Number of patients in mobile palliative care units have pain of both nociceptive and neuropathic origin. In certain cases, procedures of locoregional analgesia can be helpful.
- Trial name
- TALViSoP (NCT01094912)
- Testing
- opioids
- Where
- 6 sites in France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Limoges
Amyotrophic Lateral Sclerosis
Dysfunctions and Plasticity Mechanisms of Motor System Assessed by Cortico-cortical and Cortico-muscular Coherence Analysis in Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is characterized clinically by abnormalities of both upper motor neurons (UMN) and lower motor neurons (LMN). The presence of UMN signs is not always easy to establish.
- Trial name
- NCT01959373
- Testing
- electroencephalograms (EEG), electro-myography (EMG)
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Chemotherapeutic Agent Toxicity, Renal Toxicity
Kidney Damage in Patients Receiving Cisplatin and Ifosfamide for Solid Tumors
RATIONALE: Studying samples of blood and urine from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Conditions
- Chemotherapeutic Agent Toxicity, Renal Toxicity, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00695032
- Testing
- cisplatin, ifosfamide, laboratory biomarker analysis
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Institut Claudius Regaud