Clinical trials: in Ghana
Improving Young Child Nutrition
Integrated Education Intervention to Improve Infant and Young Child Nutrition and Growth in Ghana
In Ghana the level of malnutrition is high among children below five years of age, particularly in rural areas. The objective of the study was to investigate the effects of an education intervention aimed at addressing poor…
- Trial name
- NCT01612442
- Testing
- nutrition and agricultural education, nutrition education
- Where
- Ghana
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- McGill University
Malaria, Pneumonia
Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs
This study is to assess the value of incorporating a malaria RDT based strategy in HMM. The primary activity of the study wil be a two armed cluster randomised trial in two study sites in Uganda, one in Ghana and one in Burkina…
- Trial name
- NCT00720811
- Testing
- Artemether-lumefantrine combination, amoxycillin, paracetamol
- Where
- 4 sites in Burkina Faso, Ghana and 1 more
- Volunteers
- 6,456 people
- Sponsor
- Mbarara University of Science and Technology
Cataract Surgery
Proficiency of Eye Drop Instillation in Postoperative Cataract Patients in Ghana
Eye drops must be proficiently instilled to prevent infections following cataract surgery. Proficiency is defined as placing a drop on the ocular surface without touching the applicator's tip.
- Trial name
- NCT01181752
- Where
- Ghana
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Malaria, Schistosomiasis
Artemisinin-based Combination Therapy-Intermittent Preventive Treatment (ACT-IPT) Trial Among Schoolchildren in Kassena-Nankana, Ghana
The purpose of this study is to determine if Artemisinin-based Combination Therapy, ACT,(artemether-lumefantrine) used as intermittent preventive treatment (IPT) alone or in combination with praziquantel, will have any effects on…
- Conditions
- Malaria, Schistosomiasis, Helminthiasis, Anemia
- Trial name
- ACTIPT (NCT01459146)
- Testing
- Artemether-lumefantrine combination plus albendazole, Artemether-lumefantrine plus Praziquantel plus Albendazole, Albendazole plus Praziquantel
- Where
- Ghana
- Volunteers
- 345 people
- Sponsor
- Navrongo Health Research Centre, Ghana
Breast Cancer
Resource-sparing Post-mastectomy Radiotherapy in Breast Cancer
This study compares two different field set-ups in patients with breast cancer following a breast resection (mastectomy). These two set-ups are as follows: arm a - radiotherapy to the chest-wall only, and arm b - radiotherapy to…
- Trial name
- NCT01452672
- Testing
- Radiotherapy, Irradiation of the chest-wall and supraclavicular fossa
- Where
- 9 sites in Cuba, Egypt and 6 more
- Volunteers
- 600 people
- Sponsor
- International Atomic Energy Agency
Anemia, Low Iron Stores
Improving Iron Status Through Consumption Of Iron Fortified Cowpea: An Intervention Study
Rationale: Iron deficiency and zinc deficiency, are of public health significance in sub-Saharan Africa. An estimated 50% of children (5-14 years) in developing countries suffer from anaemia, half of which is estimated iron…
- Trial name
- NCT01208363
- Testing
- Cowpea fortified with NaFeEDTA, in form of Toubani.
- Where
- Ghana
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Malaria, Falciparum
Azithromycin Plus Chloroquine Versus Mefloquine for the Treatment of Uncomplicated Malaria in Africa
The primary objective is to confirm the hypothesis that azithromycin plus chloroquine is non-inferior to mefloquine for the treatment of symptomatic, uncomplicated malaria due to P. falciparum.
- Trial name
- NCT00082576
- Testing
- Azithromycin/Chloroquine, Mefloquine
- Where
- 6 sites in Ghana, Mali and 2 more
- Volunteers
- 238 people
- Sponsor
- Pfizer
Malaria
Correlates of Protection in Ghana
Malaria is a sickness passed from one person to the other by the bite of a mosquito. In areas of frequent malaria infection, children may develop natural protection against malaria and they are less likely to become sick or die…
- Trial name
- NCT00138307
- Where
- 2 sites in Ghana
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Buruli Ulcer, Mycobacterium Ulcerans
BURULICO Drug Trial Study Protocol: RCT SR8/SR4+CR4, GHANA
The standard for treatment Buruli ulcer disease (BUD) used to be surgery but the WHO now advises streptomycin (S, 15 mg/kg daily, intramuscularly) and rifampicin (R,10 mg/kg daily) along with surgery.
- Trial name
- BURULICO (NCT00321178)
- Testing
- SR4 - switch to CR4
- Where
- 2 sites in Ghana
- Volunteers
- 151 people
- Sponsor
- University Medical Center Groningen
Malaria
Compliance to Artesunate-Amodiaquine Therapy for Uncomplicated Malaria in Rural Ghana
With a change in malaria treatment policy to use combination antimalaria therapy, it is envisaged that compliance to combination therapy would be less than that of monotherapy that was being used for case management in Ghana.
- Trial name
- Compliance (NCT00873938)
- Where
- Ghana
- Volunteers
- 411 people
- Sponsor
- Kintampo Health Research Centre, Ghana
Malaria, Anemia
Intermittent Treatment With Sulfadoxine-pyrimethamine for Malaria Control in Infants
The purpose of this study is to assess the effectiveness of Intermittent Preventive Treatment in Infants (IPTi) with Sulfadoxine-Pyrimethamine to reduce the numbers of malaria attacks, episodes of anemia, and the overall…
- Trial name
- NCT00206739
- Testing
- Sulfadoxine (12.5 mg)/Pyrimethamine (250 mg)
- Where
- Ghana
- Volunteers
- 1,070 people, healthy volunteers welcome
- Sponsor
- Bernhard Nocht Institute for Tropical Medicine
Vitamin A Deficiency, Maternal Mortality
Trial of the Impact of Vitamin A on Maternal Mortality
Main objectives: To evaluate the impact of weekly vitamin A supplementation (VAS) to women of reproductive age (15-45 years) on maternal mortality in rural Ghana, and to compare this with the impact on overall mortality.
- Conditions
- Vitamin A Deficiency, Maternal Mortality, Maternal Morbidity
- Trial name
- ObaapaVitA (NCT00211341)
- Testing
- Vitamin A
- Where
- Ghana
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Ulcer, Herpes Genitalis
Anti-Herpetic Treatment of Genital Ulcer : Effect on HIV & Herpes Shedding (ANRS 1212)
Herpes virus type 2 (HSV-2) infection - as a cofactor of human immunodeficiency virus (HIV) transmission - can be targeted by anti-herpetic specific drugs, either as a continuous prophylactic treatment during its asymptomatic…
- Trial name
- NCT00158483
- Testing
- Acyclovir (ACV)
- Where
- 3 sites in Central African Republic, Ghana
- Volunteers
- 449 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Contraception
A Trial of Group Versus Individual Family Planning Counseling in Ghana
This study uses a randomized, noninferiority design to determine whether group family planning counseling is as effective as individual family planning counseling among gynecological patients with unmet need at two teaching…
- Trial name
- GCFP (NCT00814411)
- Testing
- group family planning counseling, Individual family planning counseling
- Where
- 3 sites in United States, Ghana
- Volunteers
- 648 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Malaria
Azithromycin Plus Chloroquine Versus Mefloquine In the Treatment of Uncomplicated P. Falciparum Malaria.
To compare Azithromycin plus Chloroquine versus Mefloquine to treat uncomplicated plasmodium falciparum malaria.
- Trial name
- NCT00367653
- Testing
- Azithromycin plus Chloroquine, Mefloquine
- Where
- 8 sites in Burkina Faso, Ghana and 4 more
- Volunteers
- 397 people
- Sponsor
- Pfizer
To Better Understand How Epicenter's (Which House Education, Health and Finance Centers in Ghana) Increase Individual's Sense of Empowerment.
Evaluating the Hunger Project in Ghana
The Hunger Project/Epicenter strategy is a community based development strategy that will positively affect health, education, empowerment, and consumption.
- Trial name
- NCT00532753
- Testing
- Community Empowerment
- Where
- Ghana
- Volunteers
- 20,000 people
- Sponsor
- University of California, Berkeley
Anaemia, Malaria
Control of Pregnancy Associated Malaria With Intermittent Preventive Treatment
Malaria is one of the major causes of illness and mortality in Sub-Saharan Africa. In Ghana, malaria is the most important cause of morbidity and accounts for about 40% of outpatient contacts.
- Trial name
- NCT00258024
- Testing
- IPT-sulphadoxinepyrimethamine
- Where
- Ghana
- Volunteers
- 420 people
- Sponsor
- DBL -Institute for Health Research and Development
Malaria, Falciparum
Randomized Trial on Effectiveness of ACTs in Ghana
The purpose of this study is to compare the effectiveness and safety of two Artemisinin Combination Therapies (ACTs) for the treatment of children with uncomplicated Plasmodium falciparum malaria
- Trial name
- NCT00374205
- Testing
- Artesunate plus Amodiaquine, Artemether-Lumefantrine
- Where
- Ghana
- Volunteers
- 245 people
- Sponsor
- Bernhard Nocht Institute for Tropical Medicine
Diarrhea
Health Impact Study of Aquatabs in Tamale, Ghana
The purpose of this study to determine whether Aquatabs, a water treatment tablet, reduces diarrheal diseases in a peri-urban population of Tamale, Ghana.
- Trial name
- NCT00252928
- Testing
- Sodium dichloroisocyanurate (NaDCC) tablets
- Where
- 3 sites in United States, Ghana
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Schistosomiasis, Soil-Transmitted Helminthiasis
Using Community-Based Volunteers to Reach Non-Enrolled School Aged Children Through Community-Directed Treatment of Schistosomiasis in School-Aged Children in Rural Northern Ghana
Schistosomiasis and soil-transmitted helminhtiasis occur throughout the developing world and are most prevalent in the poorest communitites.
- Trial name
- NCT00463931
- Where
- Ghana
- Volunteers
- 916 people
- Sponsor
- DBL -Institute for Health Research and Development