Clinical trials: in Ghana
Monkey Pox, Monkeypox
Mpox Paediatric and Adolescent Clinical Study
The goal of this multicentre, observational study on mpox in infants, children and adolescents is to increase knowledge about mpox infection and its associated disease in infants, children and adolescents.
- Trial name
- NCT05947786
- Where
- 6 sites in United States, Democratic Republic of the Congo and 4 more
- Volunteers
- 1,108 people
- Sponsor
- PENTA Foundation
Snakebite, Snake Envenomation
Mapping Snakebite Risk in Ghana and Rwanda
Snakebite causes approximately 138,000 deaths each year and non-fatal bites lead to considerable health burden, particularly in low-income tropical countries. Data on snakebite burden are lacking.
- Trial name
- NCT06808789
- Where
- Ghana
- Volunteers
- 32,000 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
SARS-CoV-2 Infection
A Study to Compare S-217622 With Placebo in Non-Hospitalized Participants With COVID-19
The main aim of this study is to evaluate the efficacy of S-217622 versus placebo among outpatient adults with mild and moderate COVID-19 starting intervention within 3 days of symptom onset.
- Trial name
- SCORPIO-HR (NCT05305547)
- Testing
- S-217622
- Where
- 196 sites in United States, Argentina and 15 more
- Volunteers
- 2,093 people
- Sponsor
- Shionogi
Medical Education
An Agentic Co-educator System for Personalized Medical Education
With the rise of generative artificial intelligence and large language models, medical education is undergoing a significant transformation.
- Trial name
- CERES (NCT06759012)
- Testing
- EyeTeacher
- Where
- 7 sites in Australia, China and 4 more
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Tsinghua University
School Attendance, School Dropouts
Peanut-based School Meals in Rural Ghana to Improve Attendance and Retention
The goal of this clinical trial is to test daily provision of peanut paste-based milk-containing ready-to-use school food (PM-RUF) in children 5-17 years of age in Ghana .
- Conditions
- School Attendance, School Dropouts, School Enrollment, School Feeding Programs
- Trial name
- Peanut-SMART (NCT06397989)
- Testing
- Ready-to-use school food, Standard meal
- Where
- 20 sites in Ghana
- Volunteers
- 5,731 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Breast Cancer Screening
Evaluating Interventions for Breast Cancer Screening in Ghana
This study aims to implement two interventions to determine the most effective one that can improve Ghanaian women's decision to get their breasts examined by a healthcare professional.
- Trial name
- NCT07745517
- Testing
- Community Health Nurse-Led Breast Cancer Screening Education, Text Messaging Breast Cancer Screening Educational Intervention, Control Arm - standard of care
- Where
- Ghana
- Volunteers
- 828 people
- Sponsor
- University of Huddersfield
Hypertensive Disorders of Pregnancy, Postpartum Hypertension
Cardiometabolic Risk in Pregnancy and Postpartum
The goal of this study is to evaluate changes in blood pressure and early cardiovascular risk markers and to determine whether a postpartum education intervention can improve cardiovascular risk monitoring among pregnant women in…
- Conditions
- Hypertensive Disorders of Pregnancy, Postpartum Hypertension, Cardiovascular Disease Risk, High Blood Pressure
- Trial name
- NCT07420465
- Testing
- Postpartum Cardiovascular Disease (CVD) Risk Reduction Program, Enhanced Postpartum Care
- Where
- Ghana
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Forgive Avorgbedor
Obstetric Fistula, Fistula
Effectiveness and Acceptability of Insertable Devices for Obstetric Fistula Management
The investigators propose a clinical trial and nested qualitative study to 1) quantify the effectiveness of an insertable vaginal cup to manage fistula urinary incontinence, 2) examine user and implementer acceptability, and 3)…
- Conditions
- Obstetric Fistula, Fistula, Fistula, Urinary, Fistula, Vaginal
- Trial name
- COPE (NCT05444504)
- Testing
- Cup, Cup+
- Where
- 3 sites in Ghana, Kenya
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Upper Resp Tract Infection
Community Interventions for Tackling Antimicrobial Resistance in Ghana
This research project aims to test the effect of two interventions targeted to community pharmacies in the Greater Accra region, Ghana, on antibiotics dispensing rates.
- Trial name
- CITAR-Ghana (NCT07284914)
- Testing
- Individualized Feedback, Legal Reminder
- Where
- Ghana
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Penn State University
HIV
Pediatric HIV Disclosure Benefits Study (PhD-BS) - Sankofa 2
The purpose of this study is to conduct a pragmatic, stepped wedge cluster randomized trial in 12 HIV pediatric clinics in Ghana to determine effectiveness, health benefits, cost and implementation to inform scale-up and…
- Trial name
- NCT04791865
- Testing
- Disclosure intervention, Usual Care
- Where
- Ghana
- Volunteers
- 748 people
- Sponsor
- Boston University
Stroke, Medication Adherence
Stroke Minimization Through Additive Anti-atherosclerotic Agents in Routine Treatment II Study (SMAART II)
The overall objective of the Stroke Minimization through Additive Anti-atherosclerotic Agents in Routine Treatment II (SMAART-II) is to deploy a hybrid study design to firstly, demonstrate the efficacy of a polypill (Polycap ®)…
- Trial name
- NCT05963568
- Testing
- Polycap
- Where
- 4 sites in Benin, Ghana and 2 more
- Volunteers
- 1,000 people
- Sponsor
- Northern California Institute of Research and Education
Cervical Cancer Screening, HIV
Home-based Self-sampling for Cervical Cancer Prevention Education Intervention in Ghana
The investigators propose to develop and/or adapt implementation strategies and a structured implementation plan to translate the HOPE intervention into existing healthcare practice in Ghana.
- Conditions
- Cervical Cancer Screening, HIV, Self-sampling, Implementation Science
- Trial name
- HOPE-inG (NCT06800664)
- Testing
- Health providers and management at IG sites will receive ISS (i.e., management support, capacity-building, and social network support) and training on the HOPE implementation plan, Control Group
- Where
- Ghana
- Volunteers
- 1,500 people
- Sponsor
- Baylor University
Preeclampsia
Optimizing the Use of Aspirin for the Prevention of Preeclampsia
Pregnant women at higher risk for preeclampsia (PE) are currently recommended to take low-dose aspirin (acetylsalicylic acid, ASA) daily from the first trimester until 36 weeks of gestation.
- Trial name
- Optim-PRE (NCT07665853)
- Testing
- Discontinuation of Acetylsalicilic acid 150 mg/day at 24-28 weeks of gestation
- Where
- 38 sites in Austria, Bulgaria and 5 more
- Volunteers
- 15,160 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Stroke
CiLostAzol for pReventIon of Recurrent sTroke in Africa
Global estimates suggest that sub-Saharan Africa (SSA) now has the highest incidence, prevalence, and worst survival outcomes of stroke.
- Trial name
- CLARITY-Africa (NCT06919835)
- Testing
- Cilostazol 100 mg
- Where
- Ghana
- Volunteers
- 1,100 people
- Sponsor
- Northern California Institute of Research and Education
Colorectal Cancer, Precancerous Polyp
A Study of a Urine Test to Detect Colorectal Cancer
The purpose of this study is to find out whether a urine test can detect colorectal cancer (CRC) and precancerous polyps in participants living in Ghana, Tanzania, and South Africa.
- Conditions
- Colorectal Cancer, Precancerous Polyp, Rectal Bleeding, CRC
- Trial name
- NCT07649057
- Testing
- 3-metabolite biosensor
- Where
- 4 sites in United States, Ghana and 2 more
- Volunteers
- 210 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
HIV Prevention and Care
Lafiya HIV-status Neutral Study - Protocol
The primary objective of this study is to adapt and evaluate the feasibility of "Lafiya," which means "Wellness" in Hausa, a multilevel intersectional stigma \& discrimination (ISD) and HIV testing intervention, to a…
- Trial name
- NCT06312514
- Testing
- LAFIYA
- Where
- Ghana
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester
Pregnancy, High Risk
PRISMA Maternal and Newborn Health Study
Access to quality antenatal care (ANC) and postnatal care (PNC), including maternal, newborn, and infant services, is integral to reducing adverse pregnancy-related health outcomes and promoting positive birth experiences.
- Trial name
- PRiSMA-MNH (NCT05904145)
- Where
- 5 sites in Ghana, India and 3 more
- Volunteers
- 267,897 people, healthy volunteers welcome
- Sponsor
- George Washington University
HIV Prevention and Care
Lafiya HIV Self-testing Study Protocol
The study aims to address low testing and related issues such as stigma, low-risk perception, and concerns about confidentiality affecting testing.
- Trial name
- NCT06238323
- Testing
- LAFIYA
- Where
- Ghana
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Rochester
COVID-19
Study of Monovalent and Bivalent Recombinant Protein Vaccines Against COVID-19 in Adults 18 Years of Age and Older
The purpose of this Phase III study is to assess the efficacy, safety, and immunogenicity of two CoV2 preS dTM-AS03 vaccines (monovalent and bivalent) as part of primary series vaccinations in a multi-stage approach, as well as a…
- Trial name
- VAT00008 (NCT04904549)
- Testing
- SARS-CoV-2 adjuvanted recombinant protein vaccine (monovalent D614) (primary series), SARS-CoV-2 adjuvanted recombinant protein vaccine (bivalent D614 + B.1.351) (primary series), SARS-CoV-2 adjuvanted recombinant protein vaccine (monovalent B.1.351) (booster dose) >= 4 months after last vaccination
- Where
- 86 sites in United States, Colombia and 9 more
- Volunteers
- 23,670 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
HIV, HIV - Human Immunodeficiency Virus
Intervention to Reduce HIV Related Stigma Among Pregnant and Postpartum Women
Purpose of this Study: The main purpose of this study is to adapt an existing evidence-based intervention, Project Accept Post-Test Support Services (PTSS) Module 3, specifically for pregnant and postpartum women living with HIV…
- Conditions
- HIV, HIV - Human Immunodeficiency Virus, Postpartum, Pregnancy
- Trial name
- WAT (NCT07064928)
- Testing
- Adapted Project Accept's Post-Test Support Services (PTSS) Module 3
- Where
- Ghana
- Volunteers
- 175 people
- Sponsor
- University of California, San Francisco