Clinical trials: in Kazakhstan
Infections, Respiratory
PA Tolerability, Safety and Pharmacokinetics in Healthy Volunteers
This is a first-in-human (FIH) study to explore the safety, tolerability and pharmacokinetics of PA after oral ascending dose administration to healthy male volunteers.
- Trial name
- PA (NCT04174937)
- Testing
- Potentiator of antibiotics (PA)
- Where
- Kazakhstan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Scientific Center for Anti-infectious Drugs, Kazakhstan
Hypertension
International Multicenter, Observational, Non-Interventional Prospective Study of Azilsartan Medoxomil in Participants With Arterial Hypertension Who Are Overweight or Obese in the Russian Federation and The Republic of Kazakhstan
The purpose of this study is to estimate antihypertensive effect of azilsartan medoxomil (Edarbi®) therapy on blood pressure in participants with overweight or obesity in routine clinical practice of hypertension (HTN) treatment…
- Trial name
- NCT02756819
- Testing
- Azilsartan Medoxomil
- Where
- 66 sites in Kazakhstan, Russia
- Volunteers
- 1,945 people
- Sponsor
- Takeda
Coronary Artery Disease
Prospective, Single-arm, Multi Centre Observations Ultimaster Des Registry
The e-Ultimaster will further validate the safety and efficacy of Ultimaster DES system in unselected patients representing everyday clinical practice.
- Trial name
- e-Ultimaster (NCT02188355)
- Where
- 462 sites in Argentina, Armenia and 48 more
- Volunteers
- 37,000 people
- Sponsor
- Terumo Europe N.V.
Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE)
Treatment of Venous Thromboembolism (VTE) With Either Rivaroxaban or Current Standard of Care Therapy
Following the findings of the clinical trials in drug development, this global non-interventional cohort field study will investigate rivaroxaban under clinical practice conditions in comparison with current standard of care for…
- Trial name
- XALIA LEA (NCT02210819)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Recommended VTE pharmacological treatments according to international guidelines
- Where
- 21 sites in Algeria, Egypt and 19 more
- Volunteers
- 1,987 people
- Sponsor
- Bayer
Breast Cancer
A Study to Investigate the Tolerability of Subcutaneous (SC) Trastuzumab Administration in Participants With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Early Breast Cancer (eBC) Using Either a Single-Use Injection Device or Manual Administration
This multicenter study in participants with HER2-positive eBC will investigate participants' pain and discomfort of SC trastuzumab (Herceptin) administered either via a single-use injection device (SID) or via vial for manual…
- Trial name
- ESCAPE (NCT02194166)
- Testing
- Trastuzumab, Paclitaxel, Docetaxel
- Where
- 7 sites in Belarus, Kazakhstan
- Volunteers
- 90 people
- Sponsor
- Hoffmann-La Roche
Gastric Cancer Stage II, Non-small Cell Lung Cancer Stage II
Oncoxin® and Quality of Life in Cancer Patients
It is expected that additional support with certain micronutrients may improve prognosis, decrease the frequency of side effects and complications and maintain high relative dose intensity of anticancer treatments.
- Conditions
- Gastric Cancer Stage II, Non-small Cell Lung Cancer Stage II, Non-small Cell Lung Cancer Stage III, Gastric Cancer Stage III
- Trial name
- NCT03550482
- Testing
- ONCOXIN®
- Where
- 9 sites in Kazakhstan, Russia
- Volunteers
- 133 people
- Sponsor
- Catalysis SL
Alcohol Dependence
Efficacy and Safety Evaluating Study of Odelepran for the Use in Patient With Alcohol Dependence
The purpose of this study was to assess efficacy and safety of the study drug Odelepran, 125 mg as compared to placebo in the treatment of alcohol dependence in adult outpatients.
- Trial name
- NCT03663374
- Testing
- Odelepan
- Where
- 22 sites in Kazakhstan, Russia
- Volunteers
- 644 people
- Sponsor
- R-Pharm
Carcinoma, Hepatocellular
Outcomes of HCC (Hepatocellular Carcinoma) Patients Treated With TACE (Transarterial Chemoembolization) and Early, Not Early or Not at All Followed by Sorafenib
This study will collect data of patients who are treated with TACE followed by sorafenib for hepatocellular carcinoma (HCC) or patients without Sorafenib after TACE.
- Trial name
- OPTIMIS (NCT01933945)
- Testing
- TACE (transarterial chemoembolization), Sorafenib (Nexavar, BAY43-9006)
- Where
- 31 sites in Austria, Brazil and 29 more
- Volunteers
- 1,676 people
- Sponsor
- Bayer
Multiple Sclerosis
Noninterventional Study Assessing Cognitive Function and Physical Activity in People With Multiple Sclerosis
Study assessing cognitive function and physical activity in people with relapsing remitting multiple sclerosis.
- Trial name
- CogniPlus (NCT01491100)
- Testing
- Interferon beta-1b (Betaseron, BAY86-5046)
- Where
- 17 sites in Albania, Algeria and 15 more
- Volunteers
- 1,085 people
- Sponsor
- Bayer
Headache Disorders, Primary, Migraine With Aura
IndoProCaf Effervescent Tablets Effectiveness in Acute Treatment of Migraine and/or Episodic Tension-type Headache and Patients' Satisfaction With the Treatment in Routine Clinical Practice
Headaches are a common medical problem that physicians frequently encounter in their practice. One of key findings of The Atlas of Headache Disorders prepared by World Health Organization (WHO) is: headache disorders, including…
- Conditions
- Headache Disorders, Primary, Migraine With Aura, Migraine Without Aura, Tension-Type Headache
- Trial name
- PRESTO (NCT02115269)
- Where
- 30 sites in Kazakhstan, Ukraine
- Volunteers
- 759 people
- Sponsor
- Abbott
Atrial Fibrillation
Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Latinamerica and EMEA Region
This international study is a prospective noninterventional observational cohort study of patients with non-valvular atrial fibrillation who are prescribed rivaroxaban under routine treatment conditions to prevent stroke or…
- Trial name
- XANTUS-EL (NCT01800006)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- 17 sites in Argentina, Azerbaijan and 15 more
- Volunteers
- 2,101 people
- Sponsor
- Bayer
Urinary Tract Infection
Levofloxacin as an Empirical Therapy in Patients With Complicated Urinary Tract Infections
Study is planned to evaluate safety and efficacy of Levolet in patients with complicated UTI
- Trial name
- Levolet-KZ16 (NCT03160807)
- Testing
- Levofloxacin
- Where
- Kazakhstan
- Volunteers
- 214 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Carcinoma, Hepatocellular
Global Investigation of Therapeutic Decisions in Hepatocellular Carcinoma and of Its Treatment With Sorafenib
In this international non-interventional study safety and clinical data concerning the treatment of patients suffering from Hepatocellular Carcinoma (HCC) will be collected.
- Trial name
- GIDEON (NCT00812175)
- Testing
- Sorafenib (Nexavar, BAY43-9006)
- Where
- 75 sites in United States, Canada and 37 more
- Volunteers
- 3,371 people
- Sponsor
- Bayer
Erectile Dysfunction
Therapeutic Effectiveness of Vardenafil in Patients With Erectile Dysfunction and Metabolic Syndrome in Daily Clinical Practice
The primary goal of this international non-interventional study is to investigate the therapeutic effectiveness of vardenafil (film-coated tablet) in Erectile Dysfunction patients with the Metabolic Syndrome in daily clinical…
- Trial name
- REVITALISE (NCT01106118)
- Testing
- Vardenafil (Levitra, BAY38-9456)
- Where
- 10 sites in Egypt, Israel and 8 more
- Volunteers
- 2,289 people
- Sponsor
- Bayer
Contraception, Menorrhagia
Mirena Observational Program
Mirena is used for long-term in Kazakhstan, and in our observational program we would like to study patients distribution per indications of Mirena, and also patient compliance within a year after Mirena insertion.
- Conditions
- Contraception, Menorrhagia, Endometrial Hyperplasia, Estrogen Replacement Therapy
- Trial name
- NCT00883662
- Testing
- Levonorgestrel (Mirena, BAY86-5028)
- Where
- Kazakhstan
- Volunteers
- 2,725 people
- Sponsor
- Bayer
Vaginal Candidiasis, Bacterial Vaginosis
Observational Program Neo-Penotran® Forte
Vaginitis is the most common gynecologic diagnosis in the primary care setting. In approximately 90 percent of affected women, this condition occurs secondary to bacterial vaginosis, vulvovaginal candidiasis, trichomoniasis or…
- Conditions
- Vaginal Candidiasis, Bacterial Vaginosis, Trichomonal Vaginitis
- Trial name
- NCT01335373
- Testing
- Metronidazole/Miconazole (Neo-Penotran Forte, BAY86-5276)
- Where
- Kazakhstan
- Volunteers
- 13,024 people
- Sponsor
- Bayer
Post-Stroke Cognitive Impairment (PSCI)
Efficacy and Safety of Actovegin in Post-stroke Cognitive Impairment (PSCI)
The aim of this trial is to provide evidence that Actovegin has a symptomatic effect in subjects with post stroke cognitive impairment (PSCI) during a six month treatment period compared to subjects administered placebo.
- Trial name
- ARTEMIDA (NCT01582854)
- Testing
- Actovegin
- Where
- 14 sites in Belarus, Kazakhstan and 1 more
- Volunteers
- 503 people
- Sponsor
- Takeda
Irregular Menstrual Cycle
Treatment Regimen in Menstrual Cycle Regularization and Persistence in Routine Clinical Practice in Russia, Ukraine, Kazakhstan and Uzbekistan
Dydrogesterone is approved in more than 100 countries including Russia, Ukraine, Kazakhstan and Uzbekistan and widely used for the treatment of progesterone deficiencies such as for management of dysmenorrhea, endometriosis…
- Trial name
- NCT01711216
- Where
- 66 sites in Kazakhstan, Russia and 2 more
- Volunteers
- 999 people
- Sponsor
- Abbott
Schizophrenia
A Study of Usage of Paliperidone Palmitate in Patients With Schizophrenia in a Hospital Setting
The purpose of this study to evaluate safety, tolerability, treatment outcomes, appropriate use and pattern of paliperidone palmitate usage in participants with schizophrenia in the hospital setting.
- Trial name
- HOSPIPalm (NCT01926912)
- Testing
- No intervention
- Where
- 39 sites in Belgium, Bulgaria and 6 more
- Volunteers
- 371 people
- Sponsor
- Janssen-Cilag International NV
Pneumonia
CAPRIVI: Community Acquired Pneumonia: Treatment With Avelox® in Hospitalized Patients
The aim of this study is to obtain data from hospitalized Community Acquired Pneumonia (CAP) patients on the disease including disease severity, clinical signs and symptoms and measures used for diagnosis in daily routine…
- Trial name
- NCT00987792
- Testing
- Moxifloxacin (Avelox, BAY12-8039)
- Where
- 11 sites in Croatia, France and 9 more
- Volunteers
- 2,595 people
- Sponsor
- Bayer