Clinical trials: completed, in Monaco
Gastrointestinal Bleeding
Efficacy of a Novel Hemostatic Powder in GI Bleeding
Hemospray™ is a new endoscopic hemostatic powder. Aims of this multicenter prospective study is to determine effectiveness of Hemospray™ on short and medium term in different clinical situations, predictive factors of rebleeding…
- Trial name
- GRAPHE (NCT02595853)
- Testing
- Non interventional study
- Where
- 19 sites in France, Monaco
- Volunteers
- 200 people
- Sponsor
- Nantes University Hospital
Mild Traumatic Brain Injury
PROtein S100B for Mild Trauma of the HEad in Emergency Patients
Brain injury is a frequent purpose for consultation in emergency services. Management of brain injury is time and resource consuming, combining clinical monitoring and imaging.
- Trial name
- PROMETHEE (NCT03313505)
- Testing
- S100B protein dosage, Brain CT scan
- Where
- 15 sites in France, Monaco
- Volunteers
- 787 people
- Sponsor
- Centre Hospitalier Princesse Grace
Rheumatoid Arthritis
Effects of Abatacept in Patients With Early Rheumatoid Arthritis
The purpose of this study is to determine if abatacept is effective in the treatment of early rheumatoid arthritis.
- Trial name
- AVERT-2 (NCT02504268)
- Testing
- Abatacept, Methotrexate
- Where
- 201 sites in United States, Argentina and 29 more
- Volunteers
- 994 people
- Sponsor
- Bristol-Myers Squibb
Multiple Sclerosis (MS), Multiple Sclerosis (MS) Relapsing Remitting
Social Cognition in Multiple Sclerosis, From a Study of Eye Movement and Gaze Strategies Using Video-oculography
This study aims to: analyze prospectively the prevalence of subclinical oculomotor disorders (OMDs) in different phenotypes of Multiple Sclerosis (MS) and to study correlations with brain MRI T2 data.
- Conditions
- Multiple Sclerosis (MS), Multiple Sclerosis (MS) Relapsing Remitting, Multiple Sclerosis (MS) Primary Progressive, Multiple Sclerosis (MS) Secondary Progressive
- Trial name
- EYE-SEP (NCT04705610)
- Testing
- Video-oculography / Social cognition tasks / Neuropsychological evaluations
- Where
- Monaco
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Association de Recherche Bibliographique pour les Neurosciences
Metabolic Preparation, Myocardial Inflammation
Impact of 100mL Lipid Emulsion for Intravenous for Suppression of Myocardial Glucose Metabolism in 18F-FDG PET/CT
There is increasing evidence that [18F]-2-fluoro-2-deoxy-D-glucose (18F-FDG) PET/CT is useful in the identification and treatment of disease processes that involve cardiac inflammation and infection.
- Trial name
- NCT04437927
- Where
- Monaco
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Princesse Grace
Coronavirus Infection
HOME-CoV: Hospitalization or Outpatient ManagEment of Patients With a SARS-CoV-2 Infection
COVID-19 pandemic has developed worldwide in less than 4 months. The clinical presentations are variable widely, ranging from simple rhinitis to major lung damage that can lead to death.
- Trial name
- HOME-CoV (NCT04338841)
- Testing
- HOME-CoV rule implementation
- Where
- 29 sites in Belgium, France and 1 more
- Volunteers
- 3,133 people
- Sponsor
- University Hospital, Angers
Rheumatoid Arthritis
VACcination In Methotrexate Treated Rheumatoid Arthritis Patients
To estimate the rate of immunological answer 1 month after antipneumococcal vaccination by the conjugated vaccine Prevenar13 ® in patients suffered from rheumatoid polyarthritis and who begin a treatement by methotrexate either…
- Trial name
- VACIMRA (NCT01942174)
- Testing
- Prevenar 13, Pneumo23 / Pneumovax, Methotrexate - Immediate
- Where
- 21 sites in France, Monaco
- Volunteers
- 276 people
- Sponsor
- University Hospital, Montpellier
Myelodysplastic Syndromes
PREDICTive FactOR of Overall Survival Among Geriatric Assessment Tools and Disease Related Factors in Elderly Patients With High Risk Myelodysplastic Syndromes.
No prospective study was conducted in elderly patients with cancer to assess the relative value of disease-related and patient-related prognosis factors.
- Trial name
- PREDICTOR (NCT02689622)
- Testing
- research of disease-related factors, research of comorbidities, physical performance
- Where
- 31 sites in France, Monaco
- Volunteers
- 157 people
- Sponsor
- University Hospital, Toulouse
COVID-19, FDG PET/CT
Assessment of Lung Inflammation With FDG PET/CT in COVID-19
The aim of the study was to assess the inflammatory status at the presumed peak of the inflammatory phase in non-critically ill patients requiring admission for COVID-19.
- Conditions
- COVID-19, FDG PET/CT, Inflammation
- Trial name
- NCT04441489
- Where
- Monaco
- Volunteers
- 13 people
- Sponsor
- Centre Hospitalier Princesse Grace
Covid19
How Routine Biomarkers and Blood Leucocytes Count Can Assist Diagnosis of COVID-19 in Emergency Department
December 2019 was the onset of an outbreak of an infection related to SARS-CoV-2, a new coronavirus detected in January 2020 and responsible for a disorder termed COVID-19.
- Trial name
- MONACOVID (NCT04401241)
- Where
- Monaco
- Volunteers
- 257 people
- Sponsor
- Centre Hospitalier Princesse Grace
Pneumococcal Infections
An Incitative Multifaceted PROcedure for Pneumococcal Vaccination at the Emergency Department
Background : Community-acquired pneumonia (CAP) is a threat in industrialized countries. It represents the 6th cause of death. CAP also frequently associates with other disorders responsible for admission and death.
- Trial name
- IMPROVED (NCT01899365)
- Where
- 18 sites in France, Monaco
- Volunteers
- 1,475 people
- Sponsor
- Centre Hospitalier Princesse Grace
Breast Cancer
Radiotherapy - Anastrazole Concomitant : Evaluation of the Side Effects
This study is a description of the radiation effects on the healthy tissues in patients receiving Anastrozole, sequential or in association with radiotherapy.
- Trial name
- ORACLES (NCT01183832)
- Where
- 29 sites in France, Monaco
- Volunteers
- 490 people
- Sponsor
- Centre Oscar Lambret
Rheumatoid Arthritis
Study to Assess the Short- and Long-term Efficacy of Certolizumab Pegol Plus Methotrexate Compared to Adalimumab Plus Methotrexate in Subjects With Moderate to Severe Rheumatoid Arthritis (RA) Inadequately Responding to Methotrexate
This study is conducted to evaluate the short (12 Weeks) and long term (104 Weeks) efficacy of Certolizumab Pegol compared with Adalimumab both in combination with Methotrexate (MTX) in the treatment of moderate to severe…
- Trial name
- NCT01500278
- Testing
- Certolizumab Pegol (CZP), Adalimumab (ADA), Methotrexate (MTX)
- Where
- 175 sites in United States, Australia and 18 more
- Volunteers
- 915 people
- Sponsor
- UCB Pharma SA
Rheumatoid Arthritis
An Observational Study of MabThera/Rituxan (Rituximab) and Alternative TNF-Inhibitors in Patients With Rheumatoid Arthritis and an Inadequate Response to a Single Previous TNF-Inhibitor
This multicenter, prospective, observational study will assess the efficacy of MabThera/Rituxan (rituximab) and alternative TNF-inhibitors in patients with rheumatoid arthritis who are non-responders or intolerant to a single…
- Trial name
- NCT01557348
- Where
- 215 sites in Canada, Colombia and 10 more
- Volunteers
- 1,239 people
- Sponsor
- Hoffmann-La Roche
Myelodysplastic Syndromes
Lenalidomide in Subject With Low and Intermediate-1 Risk MDS and Without Chromosome 5 Abnormality.
The goal of the present study is to assess, through a randomized phase II trial, the efficacy and safety of Lenalidomide with or without Epoetin beta in transfusion-dependent, ESA-resistant, IPSS low and intermediate-1 risk MDS…
- Trial name
- NCT01718379
- Testing
- Lenalidomide, Epoetin beta
- Where
- 48 sites in France, Monaco
- Volunteers
- 132 people
- Sponsor
- Groupe Francophone des Myelodysplasies
Jaundice
Prospective Randomized Study of PTC and EUS-guided Drainage of the Bile Duct
At this time, endoscopic retrograde cholangiopancreatography (ERCP) stay the gold standard method to achieve biliary drainage in case of malignant or benign stricture.
- Trial name
- NCT01499537
- Testing
- biliary drainage, EUS guided biliary drainage
- Where
- 3 sites in France, Monaco
- Volunteers
- 65 people
- Sponsor
- Institut Paoli-Calmettes
Frail Elderly Subjects
Omega-3 Fatty Acids and/or Multi-domain Intervention in the Prevention of Age-related Cognitive Decline
Epidemiological and fundamental research carried out in recent years has highlighted the role played by omega-3 fatty acids in the process of cognitive decline that accompanies advancing age and Alzheimer's disease.
- Trial name
- MAPT (NCT00672685)
- Testing
- omega-3, multi-domain intervention
- Where
- 13 sites in France, Monaco
- Volunteers
- 1,680 people
- Sponsor
- University Hospital, Toulouse
No High Risk of Hemorrhage
Efficacy of the Association Mechanical Prophylaxis + Anticoagulant Prophylaxis on Venous Thromboembolism Incidence in Intensive Care Unit (ICU)
This multicentre open-label randomized parallel-group trial aims to compare the association of intermittent pneumatic compression of the lower limbs + elastic stockings + anticoagulant prophylaxis to anticoagulant prophylaxis…
- Trial name
- CIREA2 (NCT00740987)
- Testing
- Intermittent pneumatic compression of the lower limbs
- Where
- 15 sites in France, Monaco
- Volunteers
- 621 people
- Sponsor
- University Hospital, Brest
Active Rheumatoid Arthritis, Arthritis, Rheumatoid
Study Evaluating Etanercept Plus Methotrexate in Early Rheumatoid Arthritis
Study to evaluate whether there is sustained remission and productivity in subjects with early rheumatoid arthritis started on etanercept plus methotrexate treatment.
- Conditions
- Active Rheumatoid Arthritis, Arthritis, Rheumatoid, Rheumatoid Arthritis
- Trial name
- NCT00913458
- Testing
- etanercept
- Where
- 59 sites in France, Germany and 11 more
- Volunteers
- 306 people
- Sponsor
- Pfizer
Unipolar Depression
Repetitive Transcranial Magnetic Stimulation and Venlafaxine in Depression
The purpose of this study is to assess the efficacy of add-on therapy with repetitive Transcranial Magnetic Stimulation (rTMS) and venlafaxine in the treatment of major depressive disorders compared to venlafaxine only (the…
- Trial name
- NCT00714090
- Testing
- active venlafaxine and active rTMS-repetitive transcranial magnetic stimulator, Inomed and Alpine Biomed
- Where
- 18 sites in France, Monaco
- Volunteers
- 170 people
- Sponsor
- Club rTMS et Psychiatrie