Clinical trials: in Pakistan
Scapular Dyskinesis
Scapular Stabilization Versus Proprioceptive Neuromuscular Facilitation Technique in Scapular Dyskinesis
Office workers, typically engaged in administrative or professional roles, are increasingly susceptible to scapular dyskinesis (SD).
- Trial name
- NCT07841652
- Testing
- Scapular Stabilization Exercises+ Proprioceptive Neuromuscular Facilitation, Patient engagement through warm-up and Scapular Stabilization exercises
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- University of Lahore
Postpartum Fatigue, Iron Deficiency Anemia
Maternal Fatigue After Postpartum Anemia Treatment With Intravenous Ferric Carboxymaltose and Oral Iron Therapy
Postpartum Anemia is common after childbirth and may contribute to tiredness and reduced wellbeing in mothers.This randomized controlled trial will compare two treatments for postpartum iron deficiency:intravenous ferric…
- Trial name
- MFI20 (NCT07880314)
- Testing
- INTRAVENOUS FERRIC CARBOXYMALTOSE, oral iron therapy
- Where
- Pakistan
- Volunteers
- 134 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Polycystic Ovary Syndrome
The Effect of Lifestyle Program Women With PCOS
Polycystic Ovary Syndrome (PCOS) is a common hormonal condition affecting women of reproductive age. In addition to physical symptoms such as irregular menstruation, hormonal changes, and changes in body weight, women with PCOS…
- Trial name
- PCOS (NCT07880366)
- Testing
- Lifestyle Modification Program (LMP)
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Palmoplantar Warts
Liquid Nitrogen Cryotherapy Versus CO₂ Laser for Palmoplantar Warts
This randomized clinical trial will compare the effectiveness of liquid nitrogen cryotherapy and carbon dioxide (CO₂) laser therapy for treating palmoplantar warts, which are human papillomavirus-related skin growths occurring on…
- Trial name
- NCT07881198
- Testing
- Liquid Nitrogen Cryotherapy, Carbon Dioxide (CO₂) Laser Therapy
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Bkahtawar Amin Medical and Dental College Multan
Acne Vulgaris
Clascoterone Versus Clindamycin Added to Adapalene/Benzoyl Peroxide for Moderate Facial Acne
This randomised trial compares two treatments added to the same standard acne gel in people with moderate facial acne. All participants will use adapalene 0.1%/benzoyl peroxide 2.5% gel at night.
- Trial name
- CLASCO-ACNE (NCT07881315)
- Testing
- Clascoterone 1% cream, Clindamycin 1% lotion, Adapalene 0.1%/benzoyl peroxide 2.5% gel
- Where
- Pakistan
- Volunteers
- 118 people
- Sponsor
- Allied Hospital Faisalabad
Melasma
Baseline Dermoscopic Vascular Score and Response to Oral Tranexamic Acid in Facial Melasma
Melasma is a common, long-lasting pigmentation disorder of the face. Some patients improve well with treatment and others improve little, and there is no simple way to predict this at the first visit.
- Trial name
- NCT07881328
- Testing
- Tranexamic acid, Standardised sunscreen and emollient
- Where
- Pakistan
- Volunteers
- 128 people
- Sponsor
- Allied Hospital Faisalabad
Non-Alcoholic Fatty Liver Disease
Effect of Dapagliflozin on Metabolic Parameters in Patients With Non-Alcoholic Fatty Liver Disease
This study was designed to assess the effect of dapagliflozin on body weight, blood sugar, liver enzymes, and blood fats in adults with non-alcoholic fatty liver disease (NAFLD), a condition involving excess fat accumulation in…
- Trial name
- NCT07881796
- Testing
- Dapagliflozin (10mg Tab)
- Where
- Pakistan
- Volunteers
- 146 people
- Sponsor
- Shalamar Hospital
Hearing Disorder
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan
Objective: One objective of this study is to genetically map and identify mutated genes for human hereditary hearing loss. A second objective is to study the function of these genes in the auditory system using mouse models.
- Trial name
- NCT00341874
- Where
- Pakistan
- Volunteers
- 18,009 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Atrial Fibrillation, Atrial Flutter
Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF)
The prevention of perioperative atrial fibrillation (AF) and myocardial injury after non-cardiac surgery (MINS) has the potential to reduce mortality, stroke, and hospital stays in patients undergoing major thoracic surgery.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Myocardial Injury After Non-Cardiac Surgery
- Trial name
- COP-AF (NCT03310125)
- Testing
- Active Colchicine
- Where
- 46 sites in United States, Austria and 9 more
- Volunteers
- 3,209 people
- Sponsor
- Population Health Research Institute
Sarcopenia
Ursolic Acid-Standardized Apple Phospholipid-formulated Supplementation for Muscle Strength and Physical Performance in Older Adults With Mild Sarcopenia: A Randomized, Double-Blind, Placebo-Controlled Trial
Sarcopenia is an age-related condition characterized by loss of muscle strength and physical performance, leading to increased risk of falls and disability.
- Trial name
- NCT07562698
- Testing
- Ursolic Acid-Standardized Apple Pomace Extract
- Where
- Pakistan
- Volunteers
- 105 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Chronic Non-Specific Neck Pain
Effects of Telerehabilitation and Supervised Clinic Based Rehab With Pain Neuroscience Education for Pain,Kinesiophobia and Functional Disability Among Chronic Non-Specific Neck Pain Patients
Chronic non-specific neck pain is a common musculoskeletal condition affecting a large proportion of the population worldwide. It is characterized by persistent neck pain lasting more than three months without a specific…
- Trial name
- NCT07617623
- Testing
- Telerehabilitation with Pain Neuroscience Education, Supervised Clinic Based Rehab with Pain Neuroscience Education
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Odontogenic Infection, Maxillofacial Infection
Moxifloxacin Versus Clindamycin in the Management of Odontogenic Maxillofacial Infectious Processes
Investigators are conducting a trial to compare moxifloxacin against clindamycin for dental infections that spread to the face and jaw.
- Conditions
- Odontogenic Infection, Maxillofacial Infection, Cellulitis, Cellulitis of Face
- Trial name
- NCT07810244
- Testing
- Clindamycin, Moxifloxacin (400 mg)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Nishtar Medical University
Dental Anxiety, Music Intervention
Effect of Music on Dental Anxiety and Physiological Responses During Dental Drill and Suction Sounds
Dental anxiety is common and may be triggered or increased by sounds associated with dental treatment, particularly the sound of a dental drill and suction device.
- Trial name
- MUS-DENT (NCT07827118)
- Testing
- Music intervention
- Where
- Pakistan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Unilateral S1 Nerve Root Pain
Comparison of Efficacy of Caudal Versus Transforaminal Epidural Steroid Injections in Unilateral S1 Nerve Root Pain: A Randomized Controlled Trial
This study compares caudal and transforaminal epidural steroid injections for treating unilateral S1 nerve root pain. It evaluates pain relief, functional improvement, treatment satisfaction, quality of life, and complications…
- Trial name
- NCT07833553
- Testing
- Caudal Epidural Steroid Injection (CEI), Transforaminal Epidural Steroid Injection (TFI)
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- University of Health Sciences Lahore
Forward Head Posture
Comparative Effects of Pressure and Visual Biofeedback Training on Pain, Disability, Range of Motion Among Patients With Forward Head Posture Correction: A Randomized Controlled Trial
The study will take place at Akbar Niazi Teaching Hospital and AL kauther International hospital, Bhara Kahu, Islamabad with formal permission obtained from the institution.
- Trial name
- NCT07856433
- Testing
- VISUAL FEEDBACK, Pressure Biofeedback
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ibadat International University, Islamabad
Hypertension, Primary Hypertension
Text Message Support to Help Adults With Newly Diagnosed High Blood Pressure Control Their Blood Pressure in Primary Care Clinics in Germany and Pakistan
The goal of this clinical trial is to learn if text messages can help adults with newly diagnosed high blood pressure (hypertension) bring their blood pressure under control.
- Trial name
- NCT07878728
- Testing
- mHealth Text Message Program, Usual Care
- Where
- Pakistan
- Volunteers
- 1,295 people
- Sponsor
- GIFT University
Tourniquet-induced Pain, Procedural Pain
Comparison of Ketorolac and Dexmedetomidine as An Adjunct to Lignocaine in Prevention of Tourniquet Induced Pain During Intravenous Regional Anesthesia
This study compared ketorolac and dexmedetomidine when added to lignocaine to prevent pain caused by a tourniquet during intravenous regional anesthesia.
- Trial name
- NCT07878962
- Testing
- Dexmedetomidine, ketorolac, Lidocaine
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Mayo Hospital Lahore
Obesity, Overweight
Effect of Food Temperature and Diet Composition on Satiety, Satiety Hormones, Chewing Time and Neuronal Activity
Obesity and its related illnesses have become serious health issues, obesity is today the fifth most common cause of death. Obesity rate has dramatically enhanced in both male and female, and across all ages.
- Trial name
- NCT05822167
- Testing
- High Protein Meal at Cold Temperature, High Protein Meal at Warm Temperarute, High Protein Meal at Hot Temperature
- Where
- Pakistan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Wilson's Disease
Trientine Tetrahydrochloride Administered Once a Day for the First Line Treatment of Wilson's Disease Patients.
The goal of this clinical trial is to learn if a new trientine tetrahydrochloride (TETA 4HCl) formulation administered once a day compared to d-Penicillamine (DPA) as a first line treatment for people living with Wilson's disease…
- Trial name
- TRADITiONAL (NCT07465718)
- Testing
- TETA 4HCl formulation, D-Penicillamine
- Where
- 10 sites in United States, China and 2 more
- Volunteers
- 38 people
- Sponsor
- Orphalan
Quality of Life, Sleep
Effect of Simha Pranayama and Bhramari Pranayama Relaxation Technique on Sleep and Quality of Life
Day end work related mental and muscular tension is quite common among young healthy individuals. This tension dramatically disturb sleeping pattern which also effects QoL.
- Trial name
- NCT07729267
- Testing
- Simha pranayama, Bhramari Pranayama
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mohtishim Ahmed
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